Distance-restrained docking of rifampicin and rifamycin SV to RNA polymerase using systematic FRET measurements: Developing benchmarks of model quality and reliability

Biophysical Journal

Volumn 88, Issue 2, 2005, Pages 925-938

  Knight, Jennifer L ^a   Mekler, Vladimir ^a,b   Mukhopadhyay, Jayanta ^a,b   Ebright, Richard H ^a,b   Levy, Ronald M ^a  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIFAMPICIN; RIFAMYCIN; RNA POLYMERASE; DNA DIRECTED RNA POLYMERASE; MULTIPROTEIN COMPLEX;

ACCURACY; ARTICLE; BINDING SITE; DNA RNA HYBRIDIZATION; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; FLUORESCENCE RESONANCE ENERGY TRANSFER; MACROMOLECULE; MATHEMATICAL MODEL; NONHUMAN; QUALITY CONTROL; SIMULATION; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; COMPUTER SIMULATION; EVALUATION; METHODOLOGY; MOTION; PROTEIN ANALYSIS; PROTEIN BINDING; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; ULTRASTRUCTURE; VALIDATION STUDY;

BINDING SITES; COMPUTER SIMULATION; DNA-DIRECTED RNA POLYMERASES; FLUORESCENCE RESONANCE ENERGY TRANSFER; MODELS, CHEMICAL; MODELS, MOLECULAR; MOTION; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; RIFAMPIN; RIFAMYCINS; SENSITIVITY AND SPECIFICITY;

EID: 15444372003     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.104.050187     Document Type: Article

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