메뉴 건너뛰기




Volumn 77, Issue 9, 2003, Pages 5529-5534

Itchy, a Nedd4 ubiquitin ligase, downregulates latent membrane protein 2A activity in B-cell signaling

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD19 ANTIGEN; IMMUNOGLOBULIN M; INTERLEUKIN 7; LATENT MEMBRANE PROTEIN 1; LATENT MEMBRANE PROTEIN 2A; PROTEIN ITCHY; PROTEIN TYROSINE KINASE; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

EID: 0037404527     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.9.5529-5534.2003     Document Type: Article
Times cited : (47)

References (26)
  • 1
    • 0033981052 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A-induced B-cell survival in two unique classes of EmuLMP2A transgenic mice
    • Caldwell, R. G., R. C. Brown, and R. Longnecker. 2000. Epstein-Barr virus LMP2A-induced B-cell survival in two unique classes of EmuLMP2A transgenic mice. J. Virol. 74:1101-1113.
    • (2000) J. Virol. , vol.74 , pp. 1101-1113
    • Caldwell, R.G.1    Brown, R.C.2    Longnecker, R.3
  • 2
    • 0032169313 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals
    • Caldwell, R. G., J. B. Wilson, S. J. Anderson, and R. Longnecker. 1998. Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals. Immunity 9:405-411.
    • (1998) Immunity , vol.9 , pp. 405-411
    • Caldwell, R.G.1    Wilson, J.B.2    Anderson, S.J.3    Longnecker, R.4
  • 3
    • 0035126502 scopus 로고    scopus 로고
    • Epstein-Barr virus co-opts lipid rafts to block the signaling and antigen transport functions of the BCR
    • Dykstra, M. L., R. Longnecker, and S. K. Pierce. 2001. Epstein-Barr virus co-opts lipid rafts to block the signaling and antigen transport functions of the BCR. Immunity 14:57-67.
    • (2001) Immunity , vol.14 , pp. 57-67
    • Dykstra, M.L.1    Longnecker, R.2    Pierce, S.K.3
  • 4
    • 0035817250 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling module
    • Engels, N., M. Merchant, R. Pappu, A. C. Chan, R. Longnecker, and J. Wienands. 2001. Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling module. J. Exp. Med. 194:255-264.
    • (2001) J. Exp. Med. , vol.194 , pp. 255-264
    • Engels, N.1    Merchant, M.2    Pappu, R.3    Chan, A.C.4    Longnecker, R.5    Wienands, J.6
  • 5
    • 0026019627 scopus 로고
    • Differentiation of growth signal requirement of B lymphocyte precursor is directed by expression of immunoglobulin
    • Era, T., M. Ogawa, S. Nishikawa, M. Okamoto, T. Honjo, K. Akagi, J. Miyazaki, and K. Yamamura. 1991. Differentiation of growth signal requirement of B lymphocyte precursor is directed by expression of immunoglobulin. EMBO J. 10:337-342.
    • (1991) EMBO J. , vol.10 , pp. 337-342
    • Era, T.1    Ogawa, M.2    Nishikawa, S.3    Okamoto, M.4    Honjo, T.5    Akagi, K.6    Miyazaki, J.7    Yamamura, K.8
  • 7
    • 9444288215 scopus 로고    scopus 로고
    • Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transduction
    • Fruehling, S., S. K. Lee, R. Herrold, B. Frech, G. Laux, E. Kremmer, F. A. Grasser, and R. Longnecker. 1996. Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transduction. J. Virol. 70:6216-6226.
    • (1996) J. Virol. , vol.70 , pp. 6216-6226
    • Fruehling, S.1    Lee, S.K.2    Herrold, R.3    Frech, B.4    Laux, G.5    Kremmer, E.6    Grasser, F.A.7    Longnecker, R.8
  • 8
    • 0030754766 scopus 로고    scopus 로고
    • The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction
    • Fruehling, S., and R. Longnecker. 1997. The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction. Virology 235:241-251.
    • (1997) Virology , vol.235 , pp. 241-251
    • Fruehling, S.1    Longnecker, R.2
  • 9
    • 0031661310 scopus 로고    scopus 로고
    • Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency
    • Fruehling, S., R. Swart, K. M. Dolwick, E. Kremmer, and R. Longnecker. 1998. Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency. J. Virol. 72:7796-7806.
    • (1998) J. Virol. , vol.72 , pp. 7796-7806
    • Fruehling, S.1    Swart, R.2    Dolwick, K.M.3    Kremmer, E.4    Longnecker, R.5
  • 10
    • 85031646563 scopus 로고    scopus 로고
    • B-cell commitment, development and selection
    • Hardy, R. R. 2000. B-cell commitment, development and selection. Curr. Opin. Immunol. 12:346-353.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 346-353
    • Hardy, R.R.1
  • 11
    • 0034007009 scopus 로고    scopus 로고
    • The Epstein-Barr virus latent membrane protein 2A PY motif recruits WW domain-containing ubiquitin-protein ligases
    • Ikeda, M., A. Ikeda, L. C. Longan, and R. Longnecker. 2000. The Epstein-Barr virus latent membrane protein 2A PY motif recruits WW domain-containing ubiquitin-protein ligases. Virology 268:178-191.
    • (2000) Virology , vol.268 , pp. 178-191
    • Ikeda, M.1    Ikeda, A.2    Longan, L.C.3    Longnecker, R.4
  • 12
    • 0036382917 scopus 로고    scopus 로고
    • Lysine-independent ubiquitination of Epstein-Barr virus LMP2A
    • Ikeda, M., A. Ikeda, and R. Longnecker. 2002. Lysine-independent ubiquitination of Epstein-Barr virus LMP2A. Virology 300:153-159.
    • (2002) Virology , vol.300 , pp. 153-159
    • Ikeda, M.1    Ikeda, A.2    Longnecker, R.3
  • 13
    • 0035009189 scopus 로고    scopus 로고
    • PY motifs of Epstein-Barr virus LMP2A regulate protein stability and phosphorylation of LMP2A-associated proteins
    • Ikeda, M., A. Ikeda, and R. Longnecker. 2001. PY motifs of Epstein-Barr virus LMP2A regulate protein stability and phosphorylation of LMP2A-associated proteins. J. Virol. 75:5711-5718.
    • (2001) J. Virol. , vol.75 , pp. 5711-5718
    • Ikeda, M.1    Ikeda, A.2    Longnecker, R.3
  • 14
    • 0001658316 scopus 로고    scopus 로고
    • Epstein-Barr virus and its replication
    • B. N. Fields, D. M, Knipe, and P. M. Howley (ed.), Lippincoft-Raven, New York, N.Y.
    • Kieff, E. 1996. Epstein-Barr virus and its replication, p. 1109-1162. In B. N. Fields, D. M, Knipe, and P. M. Howley (ed.), Fundamental virology. Lippincoft-Raven, New York, N.Y.
    • (1996) Fundamental Virology , pp. 1109-1162
    • Kieff, E.1
  • 15
    • 0001403023 scopus 로고    scopus 로고
    • Molecular biology of Epstein-Barr virus
    • D. J. McCance (ed.), American Society for Microbiology, Washington, D.C.
    • Longnecker, R. 1998. Molecular biology of Epstein-Barr virus, p. 133-172. In D. J. McCance (ed.), Human tumor viruses. American Society for Microbiology, Washington, D.C.
    • (1998) Human Tumor Viruses , pp. 133-172
    • Longnecker, R.1
  • 16
    • 0025305417 scopus 로고
    • A second Epstein-Barr virus membrane protein (LMP2) is expressed in latent infection and colocalizes with LMP1
    • Longnecker, R., and E. Kieff. 1990. A second Epstein-Barr virus membrane protein (LMP2) is expressed in latent infection and colocalizes with LMP1. J. Virol. 64:2319-2326.
    • (1990) J. Virol. , vol.64 , pp. 2319-2326
    • Longnecker, R.1    Kieff, E.2
  • 17
    • 0033808329 scopus 로고    scopus 로고
    • The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo
    • Merchant, M., R. G. Caldwell, and R. Longnecker. 2000. The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo. J. Virol. 74:9115-9124.
    • (2000) J. Virol. , vol.74 , pp. 9115-9124
    • Merchant, M.1    Caldwell, R.G.2    Longnecker, R.3
  • 18
    • 0035814496 scopus 로고    scopus 로고
    • LMP2A survival and developmental signals are transmitted through Btk-dependent and Btk-independent pathways
    • Merchant, M., and R. Longnecker. 2001. LMP2A survival and developmental signals are transmitted through Btk-dependent and Btk-independent pathways. Virology 291:46-54.
    • (2001) Virology , vol.291 , pp. 46-54
    • Merchant, M.1    Longnecker, R.2
  • 19
    • 0028970289 scopus 로고
    • Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases
    • Miller, C. L., A. L. Burkhardt, J. H. Lee, B. Stealey, R. Longnecker, J. B. Bolen, and E. Kieff. 1995. Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases. Immunity 2:155-166.
    • (1995) Immunity , vol.2 , pp. 155-166
    • Miller, C.L.1    Burkhardt, A.L.2    Lee, J.H.3    Stealey, B.4    Longnecker, R.5    Bolen, J.B.6    Kieff, E.7
  • 21
    • 0037213918 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A interferes with global transcription factor regulation when expressed during B-lymphocyte development
    • Portis, T., and R. Longnecker. 2003. Epstein-Barr virus LMP2A interferes with global transcription factor regulation when expressed during B-lymphocyte development. J. Virol. 77:105-114.
    • (2003) J. Virol. , vol.77 , pp. 105-114
    • Portis, T.1    Longnecker, R.2
  • 22
    • 0024535280 scopus 로고
    • Two related Epstein-Barr virus membrane proteins are encoded by separate genes
    • Sample, J., D. Liebowitz, and E. Kieff. 1989. Two related Epstein-Barr virus membrane proteins are encoded by separate genes. J. Virol. 63:933-937.
    • (1989) J. Virol. , vol.63 , pp. 933-937
    • Sample, J.1    Liebowitz, D.2    Kieff, E.3
  • 24
    • 0035316576 scopus 로고    scopus 로고
    • Cb1: Many adaptafions adaptations to regulate protein tyrosine kinases
    • Thien, C. B., and W. Y. Langdon. 2001. Cb1: many adaptafions adaptations to regulate protein tyrosine kinases. Nat. Rev. Mol. Cell. Biol. 2:294-307.
    • (2001) Nat. Rev. Mol. Cell. Biol. , vol.2 , pp. 294-307
    • Thien, C.B.1    Langdon, W.Y.2
  • 25
    • 0035496101 scopus 로고    scopus 로고
    • Epstein-Barr virus: Exploiting the immune system
    • Thorley-Lawson, D. A. 2001. Epstein-Barr virus: exploiting the immune system. Nat. Rev. Immunol. 1:75-82.
    • (2001) Nat. Rev. Immunol. , vol.1 , pp. 75-82
    • Thorley-Lawson, D.A.1
  • 26
    • 0033756590 scopus 로고    scopus 로고
    • Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases
    • Winberg, G., L. Matskova, F. Chen, P. Plant, D. Rotin, G. Gish, R. Ingham, I. Ernberg, and T. Pawson. 2000. Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases. Mol. Cell. Biol. 20:8526-8535.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8526-8535
    • Winberg, G.1    Matskova, L.2    Chen, F.3    Plant, P.4    Rotin, D.5    Gish, G.6    Ingham, R.7    Ernberg, I.8    Pawson, T.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.