Origins and functions of B-1 cells with notes on the role of CD5

Annual Review of Immunology

Volumn 20, Issue , 2002, Pages 253-300

  Berland, Robert ^a   Wortis, Henry H ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antigen; Autoimmunity; B cells; Repertoire; T independent type 2 (TI 2); Tolerance

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD5 ANTIGEN; DNA NUCLEOTIDYLEXOTRANSFERASE; IMMUNOGLOBULIN;

ANTIGEN FUNCTION; ANTIGEN SPECIFICITY; AUTOIMMUNITY; B LYMPHOCYTE; HUMAN; MUCOSAL IMMUNITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; STEM CELL; TRANSGENE;

ANIMALS; ANTIGENS, CD5; AUTOIMMUNITY; B-LYMPHOCYTE SUBSETS; BONE MARROW CELLS; CELL DIFFERENTIATION; FETUS; HUMANS; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN M; LYMPHOCYTE ACTIVATION; MICE; PHENOTYPE; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION;

EID: 0036217975     PISSN: 07320582     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.immunol.20.100301.064833     Document Type: Review

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249. CD5 is associated with the human B cell antigen receptor complex
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251. CD5 is phosphorylated on tyrosine after stimulation of the T-cell antigen receptor complex
252. Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase
253. CD5 negatively regulates the T-cell antigen receptor signal transduction pathway: Involvement of SH2-containing phosphotyrosine phosphatase SHP-1
254. Specificity of the SH2 domains of SHP-1 in the interaction with the immunoreceptor tyrosine-based inhibitory motif-bearing receptor gp49B
255. The pseudo-immunoreceptor tyrosine-based activation motif of CD5 mediates its inhibitory action on B-cell receptor signaling
256. Negative regulation of antigen receptor-mediated signaling by constitutive association of CD5 with the SHP-1 protein tyrosine phosphatase in B-1 B cells
257. +/calmodulin-dependent kinase IIdelta
258. Anti-immunoglobulin M activates nuclear calcium/calmodulin-dependent protein kinase II in human B lymphocytes
259. Regulation of casein kinase 2 by direct interaction with cell surface receptor CD5
260. Human CD5 signaling and constitutive phosphorylation of C-terminal serine residues by casein kinase II
261. Interaction of CD163 with the regulatory subunit of casein kinase II (CKII) and dependence of CD 163 signaling on CKII and protein kinase C
262. Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists
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264. A role for CD5 in TCR-mediated signal transduction and thymocyte selection
265. Several different cell surface molecules control negative selection of medullary thymocytes
266. Negative regulation of CD4 lineage development and responses by CD5
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268. The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response
269. Defective B cell development and function in Btk-deficient mice
270. Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage
271. Immunodeficiency in protein kinase c-beta-deficient mice
272. Phospholipase C-gamma-2 is essential in the functions of B-cell and several Fc-receptors
273. Cutting edge: Essential role of phospholipase C-gamma 2 in B cell development and function
274. Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85-alpha
275. Xid-like immunodeficiency in mice with disruption of the p85-alpha subunit of phosphoinositide 3-kinase
276. Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule
277. Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice
278. An essential role for BLNK in human B cell development
279. Requirement for B cell linker protein (BLNK) in B cell development
280. Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65
281. The B cell-restricted adaptor BASH is required for normal development and antigen receptor-mediated activation of B cells
282. Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen
283. Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2
284. Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav
285. Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene
286. oct-2 gene disruption eliminates the peritoneal B-1 lymphocyte lineage and attenuates B-2 cell maturation and function
287. Aiolos regulates B cell activation and maturation to effector state
288. + B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses
289. Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5R alpha-deficient mice
290. Deficiency of IL-5 receptor alpha-chain selectively influences the development of the common mucosal immune system independent IgA-producing B-1 cell in mucosa-associated tissues
291. Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development
292. + B cells in viable motheaten and normal mice
293. CD72-deficient mice reveal nonredundant roles of CD72 in B cell development and activation
294. CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity
295. An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes
296. Transgenic mice expressing a B cell growth and differentiation factor gene (interleukin 5) develop eosinophilia and autoantibody production
297. Interleukin 9-induced in vivo expansion of the B-1 lymphocyte population
298. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes
299. Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection