Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen

Journal of Experimental Medicine

Volumn 194, Issue 11, 2001, Pages 1691-1697

  Schneider, Pascal ^a   Takatsuka, Hisakazu ^a   Wilson, Anne ^a   Mackay, Fabienne ^b   Tardivel, Aubry ^a   Lens, Susanne ^a   Cachero, Teresa G ^c   Finke, Daniela ^a   Beermann, Friedrich ^a   Tschopp, Jürg ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b ST VINCENT S HOSPITAL   (Australia)

^c BIOGEN   (United States)

Author keywords

Ligand; Lymphocyte; Receptor; TNF; Transgene

Indexed keywords

ANTIGEN; APRIL PROTEIN; B CELL ACTIVATING FACTOR; B CELL MATURATION ANTIGEN; LIGAND; RECEPTOR; TRANSMEMBRANE ACTIVATOR AND CYCLOPHILIN LIGAND INTERACTOR; TUMOR NECROSIS FACTOR DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE DIFFERENTIATION; CELL MATURATION; HOMEOSTASIS; LYMPHOCYTOPENIA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; B-CELL ACTIVATING FACTOR; B-CELL MATURATION ANTIGEN; B-LYMPHOCYTES; CELL DIFFERENTIATION; HUMANS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; RECEPTORS, TUMOR NECROSIS FACTOR; TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035803468     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.11.1691     Document Type: Article

References (29)

1. B cell development pathways
2. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals
3. Selection events operating at various stages in B cell development
4. T-Independent immune response: New aspects of B cell biology
5. A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria
6. B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory"
7. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
8. Severe B cell hyperptasia and autoimmune disease in TALL-1 transgenic mice
9. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
10. Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI
11. APRIL and TALL-I and receptors BCMA and TACI: System for regulating humoral immunity
12. B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses
13. Regulation of the T-independent humoral response by TACI
14. Activation and accumulation of B cells in TACI-deficient mice
15. Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections
16. BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population
17. Effect of mature lymphocytes and lymphotoxin on the development of the follicle-associated epithelium and M cells in mouse Peyer's patches
18. BAFF mediates survival of peripheral immature B lymphocytes
19. Rapid elimination of mature autoreactive B cells demonstrated by Cre-induced change in B cell antigen receptor specificity in vivo
20. Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response
21. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
22. Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease
23. The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression
24. Baff-r, a newly identified TNF receptor that specifically interacts with BAFF
25. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. Impaired B cell maturation in mice lacking blys
26. Bcmd decreases the life span of B-2 but not B-1 cells in A/WySnJ mice
27. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
28. Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor
29. B-cell commitment, development and selection