Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells

Journal of Experimental Medicine

Volumn 184, Issue 4, 1996, Pages 1495-1505

  Kanzler, Holger ^a   Küppers, Ralf ^a   Hansmann, Martin Leo ^a   Rajewsky, Klaus ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; CLONE; FEMALE; GENE REARRANGEMENT; GERMINAL CENTER; HODGKIN DISEASE; HUMAN; HUMAN CELL; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REED STERNBERG CELL; SOMATIC MUTATION; STOP CODON;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; B-LYMPHOCYTES; BASE SEQUENCE; CELL LINEAGE; FEMALE; GENE REARRANGEMENT, B-LYMPHOCYTE; GERMINAL CENTER; HODGKIN DISEASE; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOHISTOCHEMISTRY; MALE; MICROMANIPULATION; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; REED-STERNBERG CELLS; SEQUENCE ANALYSIS, DNA;

EID: 0029952779     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.184.4.1495     Document Type: Article

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