The origin of Hodgkin and Reed/Sternberg cells in Hodgkin's disease

Annual Review of Immunology

Volumn 16, Issue , 1998, Pages 471-493

  Küppers, Ralf ^a   Rajewsky, Klaus ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Clonality; Epstein Barr virus; Germinal center; Single cell studies; Somatic hypermutation

Indexed keywords

CD15 ANTIGEN; CD20 ANTIGEN; CD30 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ANTIGEN SPECIFICITY; APOPTOSIS; CELL LINE; CLONING; EPSTEIN BARR VIRUS; GENE MUTATION; GERMINAL CENTER; HODGKIN DISEASE; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN GENE; LYMPHOMA; POLYCLONAL ACTIVATION; PRIORITY JOURNAL; REED STERNBERG CELL; REVIEW; STEM CELL;

ANIMALS; CLONE CELLS; GENE REARRANGEMENT; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 4, HUMAN; HODGKIN DISEASE; HUMANS; REED-STERNBERG CELLS; TUMOR VIRUS INFECTIONS;

EID: 0031919997     PISSN: 07320582     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.immunol.16.1.471     Document Type: Review

References (14)

1. Hodgkin T. 1832. On some morbid appearances of the absorbent glands and spleen. Med. Chir. Trans. 17:68-114
2. Reed D. 1902. On the pathological changes in Hodgkin's disease, with special reference to its relationship to tuberculosis. J. Hopkins Hasp. Rep. 10:133-96
3. Stemberg C. 1898. Über eine eigenartige unter dem Bilde der Pseudoleukämie verlaufende Tuberkulose des lymphatischen Apparates. Z. Heilkunde 19:21-90
4. Drexler HG. 1992. Recent results on the biology of Hodgkin and Reed-Stemberg cells. I. Biopsy material. Leuk. Lymph. 8:283-313
5. Burke JS. 1992. Hodgkin's disease: histopathology and differential diagnosis. In Neoplastic Hematopathology, ed. DM Knowles, pp. 497-533. Baltimore: Williams & Wilkins
6. Harris ML, Jaffe ES, Stein H, Banks PM, Chan JKC, Cleary ML, Delsol G, de Wolf-Peeters C, Falini B, Gatter KC, Grogan TM, Isaacson PG, Knowles DM, Mason DY, Müller-Hermelink HK, Pileri SA, Pins MA, Ralkiaer E, Warnke RA. 1994. A revised European-American classification of lymphoid neoplasms: a proposal from the international lymphoma study group. Blood 84:1361-92
7. Mason DY, Banks PM, Chan J, Cleary ML, Delsol G, de Wolf Peelers C, Falini B, Gatter K, Grogan TM, Harris NL, Isaacson PG, Jaffe ES, Knowles DM, Müller-Hermelink HK, Pileri S, Ralfkiaer E, Stein H, Warnke R. 1994. Nodular lymphocyte predominance Hodgkin's disease. A clinicopathological entity. Am. J. Surg. Pathol. 18:526-30
8. Trümper L, Brady G, Bagg A, Gray D, Loke SL, Griesser H, Wagman R, Braziel R, Gascoyne RD, Vicini S, Iscove NN, Cossman J, Mak TW. 1993. Single-cell analysis of Hodgkin and Reed-Sternberg cells: molecular heterogeneity of gene expression and p53 mutations. Blood 81: 3097-15
9. Waldmann TA. 1987. The arrangement of immunoglobulin and T cell receptor genes in human lymphoproliferative disorders. Adv. Immunol. 40:247-321
10. Drexler HG. 1993. Recent results on the biology of Hodgkin and Reed-Stemberg cells. II. Continuous cell lines. Leuk. Lymph. 9:1-25
11. Bargou RC, Mapara MY, Zugck C, Daniel PT, Pawlita M, Döhner H, Dörken B. 1993. Characterization of a novel Hodgkin cell line, HD-Myz, with myelomonocytoid features mimicking Hodgkin's disease in severe combined immunodeficient mice. J. Exp. Med. 177:1257-68
12. Wolf J, Kapp U, Bohlen H, Kornacker M, Schoch C, Stahl B, Mücke S, von Kalle C, Fonatsch C, Schaefer HE, Hansmann ML, Diehl V. 1996. Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Stemberg cells. Blood 87:3418-28
13. Kanzler H, Hansmann ML, Kapp U, Wolf J, Diehl V, Rajewsky K, Küppers R. 1996. Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient. Blood 87:3429-36
14. Barrios L, Caballin MR, Miro R, Fuster C, Berrozpe G, Subias A, Batlle X, Egpzcue J. 1988. Chromosomal abnormalities in peripheral blood lymphocytes from untreated Hodgkin's patients. Hum. Genetics 78:320-24