-
3
-
-
0034214261
-
Nicotinic receptor function: New perspectives from knockout mice
-
M. Cordero-Erausquin, L. M. Marubio, R. Klink, and J. P. Changeux, "Nicotinic receptor function: new perspectives from knockout mice," Trends Pharmacol. Sci., vol. 21, pp. 211-217, 2000.
-
(2000)
Trends Pharmacol. Sci.
, vol.21
, pp. 211-217
-
-
Cordero-Erausquin, M.1
Marubio, L.M.2
Klink, R.3
Changeux, J.P.4
-
5
-
-
0001930724
-
-
D. L. Martin and R. W. Olsen, Eds. Philadelphia, PA: Lippincott
-
H. Mohler, D. Benke, J. M. Fritschy, and J. Benson, The Benzodiazepine Site of GABAA Receptors, in GABA in the Nervous System: The View at 50 Years, D. L. Martin and R. W. Olsen, Eds. Philadelphia, PA: Lippincott, 2000, pp. 97-112.
-
(2000)
The Benzodiazepine Site of GABAA Receptors, in GABA in the Nervous System: the View at 50 Years
, pp. 97-112
-
-
Mohler, H.1
Benke, D.2
Fritschy, J.M.3
Benson, J.4
-
6
-
-
0030441739
-
Molecular and genetic insights into ligand binding and signal transduction at the inhibitory glycine receptor
-
P. R. Schofield, J. W. Lynch, S. Rajendra, K. D. Pierce, C. A. Handford, and P. H. Barry, "Molecular and genetic insights into ligand binding and signal transduction at the inhibitory glycine receptor," in Proc. Cold Spring Harbor Symp. Quantitative Biology, vol. 61, 1996, pp. 333-342.
-
(1996)
Proc. Cold Spring Harbor Symp. Quantitative Biology
, vol.61
, pp. 333-342
-
-
Schofield, P.R.1
Lynch, J.W.2
Rajendra, S.3
Pierce, K.D.4
Handford, C.A.5
Barry, P.H.6
-
7
-
-
3543062342
-
Ligand-gated ion channels: Mechanisms underlying ion selectivity
-
A. Keramidas, A. J. Moorhouse, P. R. Schofield, and P. H. Barry, "Ligand-gated ion channels: mechanisms underlying ion selectivity," Prog. Biophys. Mol. Biol., vol. 86, pp. 161-204, 2004.
-
(2004)
Prog. Biophys. Mol. Biol.
, vol.86
, pp. 161-204
-
-
Keramidas, A.1
Moorhouse, A.J.2
Schofield, P.R.3
Barry, P.H.4
-
8
-
-
0027506299
-
Nicotinic acetylcholine receptor at 9 A resolution
-
N. Unwin, "Nicotinic acetylcholine receptor at 9 A resolution," J. Mol. Biol., vol. 229, pp. 1101-1124, 1993.
-
(1993)
J. Mol. Biol.
, vol.229
, pp. 1101-1124
-
-
Unwin, N.1
-
9
-
-
0032967642
-
Nicotinic acetylcholine receptor at 4.6 A resolution: Transverse tunnels in the channel wall
-
A. Miyazawa, Y. Fujiyoshi, M. Stowell, and N. Unwin, "Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall," J. Mol. Biol., vol. 288, pp. 765-786, 1999.
-
(1999)
J. Mol. Biol.
, vol.288
, pp. 765-786
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Stowell, M.3
Unwin, N.4
-
10
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
K. Brejc, W. J. van Dijk, R. V. Klaassen, M. Schuurmans, J. van der Oost, A. B. Smit, and T. K. Sixma, "Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors," Nature, vol. 411, pp. 269-276, 2001.
-
(2001)
Nature
, vol.411
, pp. 269-276
-
-
Brejc, K.1
Van Dijk, W.J.2
Klaassen, R.V.3
Schuurmans, M.4
Van Der Oost, J.5
Smit, A.B.6
Sixma, T.K.7
-
11
-
-
2142710947
-
Guide to receptors and channels, 1st edition
-
S. P. Alexander, A. Mathie, and J. A. Peters, "Guide to receptors and channels, 1st edition," Br. J. Pharmacol., vol. 141, pp. S1-S126, 2004.
-
(2004)
Br. J. Pharmacol.
, vol.141
-
-
Alexander, S.P.1
Mathie, A.2
Peters, J.A.3
-
12
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
A. Miyazawa, Y. Fujiyoshi, and N. Unwin, "Structure and gating mechanism of the acetylcholine receptor pore," Nature, vol. 423, pp. 949-955, 2003.
-
(2003)
Nature
, vol.423
, pp. 949-955
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Unwin, N.3
-
13
-
-
0242488935
-
Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy
-
N. Unwin, "Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy," FEBS Lett., vol. 555, pp. 91-95, 2003.
-
(2003)
FEBS Lett.
, vol.555
, pp. 91-95
-
-
Unwin, N.1
-
14
-
-
0034731271
-
The Croonian lecture 2000. Nicotinic acetylcholine receptor and the structural basis of fast synaptic transmission
-
_, "The Croonian lecture 2000. Nicotinic acetylcholine receptor and the structural basis of fast synaptic transmission," Philos. Trans. R. Soc. London B, Biol. Sci., vol. 355, pp. 1813-1829, 2000.
-
(2000)
Philos. Trans. R. Soc. London B, Biol. Sci.
, vol.355
, pp. 1813-1829
-
-
-
15
-
-
4344616080
-
Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel
-
C. Bouzat, F. Gumilar, G. Spitzmaul, H. L. Wang, D. Rayes, S. B. Hansen, P. Taylor, and S. M. Sine, "Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel," Nature, vol. 430, pp. 896-900, 2004.
-
(2004)
Nature
, vol.430
, pp. 896-900
-
-
Bouzat, C.1
Gumilar, F.2
Spitzmaul, G.3
Wang, H.L.4
Rayes, D.5
Hansen, S.B.6
Taylor, P.7
Sine, S.M.8
-
16
-
-
17544372511
-
Nicotinic receptors at the amino acid level
-
P. J. Corringer, N. Le Novere, and J. P. Changeux, "Nicotinic receptors at the amino acid level," Annu. Rev. Pharmacol. Toxicol., vol. 40, pp. 431-458, 2000.
-
(2000)
Annu. Rev. Pharmacol. Toxicol.
, vol.40
, pp. 431-458
-
-
Corringer, P.J.1
Le Novere, N.2
Changeux, J.P.3
-
17
-
-
4644265039
-
Molecular structure and function of the glycine receptor chloride channel
-
J. W. Lynch, "Molecular structure and function of the glycine receptor chloride channel," Physiol. Rev., vol. 84, pp. 1051-1095, 2004.
-
(2004)
Physiol. Rev.
, vol.84
, pp. 1051-1095
-
-
Lynch, J.W.1
-
18
-
-
0019441262
-
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
-
O. P. Hamill, A. Marty, E. Neher, B. Sakmann, and F. J. Sigworth, "Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches," Pflugers Arch., vol. 391, pp. 85-100, 1981.
-
(1981)
Pflugers Arch.
, vol.391
, pp. 85-100
-
-
Hamill, O.P.1
Marty, A.2
Neher, E.3
Sakmann, B.4
Sigworth, F.J.5
-
19
-
-
15244355046
-
Fifty years of progress in ion channel research
-
Mar.
-
P. C. Jordan, "Fifty years of progress in ion channel research," IEEE Trans. Nanobiosci., vol. 4, no. 1, pp. 1-9, Mar. 2005.
-
(2005)
IEEE Trans. Nanobiosci.
, vol.4
, Issue.1
, pp. 1-9
-
-
Jordan, P.C.1
-
20
-
-
0027224010
-
Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers
-
J. Bormann, N. Rundstrom, H. Betz, and D. Langosch, "Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers," EMBO J., vol. 12, pp. 3729-3737, 1993.
-
(1993)
EMBO J.
, vol.12
, pp. 3729-3737
-
-
Bormann, J.1
Rundstrom, N.2
Betz, H.3
Langosch, D.4
-
21
-
-
0028831226
-
Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonists
-
S. Rajendra, J. W. Lynch, K. D. Pierce, C. R. French, P. H. Barry, and P. R. Schofield, "Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonists," Neuron, vol. 14, pp. 169-175, 1995.
-
(1995)
Neuron
, vol.14
, pp. 169-175
-
-
Rajendra, S.1
Lynch, J.W.2
Pierce, K.D.3
French, C.R.4
Barry, P.H.5
Schofield, P.R.6
-
22
-
-
0001802726
-
Ionic selectivity of channels at the end plate
-
P. H. Barry and P. W. Gage, "Ionic selectivity of channels at the end plate," Curr. Top. Membr. Transport, vol. 21, pp. 1-51, 1984.
-
(1984)
Curr. Top. Membr. Transport
, vol.21
, pp. 1-51
-
-
Barry, P.H.1
Gage, P.W.2
-
23
-
-
0023748825
-
Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance
-
K. Imoto, C. Busch, B. Sakmann, M. Mishina, T. Konno, J. Nakai, H. Bujo, Y. Mori, K. Fukuda, and S. Numa, "Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance," Nature, vol. 335, pp. 645-648, 1988.
-
(1988)
Nature
, vol.335
, pp. 645-648
-
-
Imoto, K.1
Busch, C.2
Sakmann, B.3
Mishina, M.4
Konno, T.5
Nakai, J.6
Bujo, H.7
Mori, Y.8
Fukuda, K.9
Numa, S.10
-
24
-
-
0028016521
-
Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia
-
D. Langosch, B. Laube, N. Rundstrom, V. Schmieden, J. Bormann, and H. Betz, "Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia," EMBO J., vol. 13, pp. 4223-4228, 1994.
-
(1994)
EMBO J.
, vol.13
, pp. 4223-4228
-
-
Langosch, D.1
Laube, B.2
Rundstrom, N.3
Schmieden, V.4
Bormann, J.5
Betz, H.6
-
25
-
-
0035999832
-
Single channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channels
-
A. J. Moorhouse, A. Keramidas, A. Zaykin, P. R. Schofield, and P. H. Barry, "Single channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channels," J. Gen. Physiol., vol. 119, pp. 411-425, 2002.
-
(2002)
J. Gen. Physiol.
, vol.119
, pp. 411-425
-
-
Moorhouse, A.J.1
Keramidas, A.2
Zaykin, A.3
Schofield, P.R.4
Barry, P.H.5
-
26
-
-
0041806486
-
A cytoplasmic region determines single-channel conductance in 5-HT3 receptors
-
S. P. Kelley, J. I. Dunlop, E. F. Kirkness, J. J. Lambert, and J. A. Peters, "A cytoplasmic region determines single-channel conductance in 5-HT3 receptors," Nature, vol. 424, pp. 321-324, 2003.
-
(2003)
Nature
, vol.424
, pp. 321-324
-
-
Kelley, S.P.1
Dunlop, J.I.2
Kirkness, E.F.3
Lambert, J.J.4
Peters, J.A.5
-
27
-
-
0030848203
-
Hippocampal GABA(A) channel conductance increased by diazepam
-
M. Eghbali, J. P. Curmi, B. Birnir, and P. W. Gage, "Hippocampal GABA(A) channel conductance increased by diazepam," Nature, vol. 388, pp. 71-75, 1997.
-
(1997)
Nature
, vol.388
, pp. 71-75
-
-
Eghbali, M.1
Curmi, J.P.2
Birnir, B.3
Gage, P.W.4
-
28
-
-
0026082583
-
Location of a threonine residue in the alpha-subunit M2 transmembrane segment that determines the ion flow through the acetylcholine receptor channel
-
A. Villarroel, S. Herlitze, M. Koenen, and B. Sakmann, "Location of a threonine residue in the alpha-subunit M2 transmembrane segment that determines the ion flow through the acetylcholine receptor channel," Proc. R. Soc. London B, Biol. Sci., vol. 243, pp. 69-74, 1991.
-
(1991)
Proc. R. Soc. London B, Biol. Sci.
, vol.243
, pp. 69-74
-
-
Villarroel, A.1
Herlitze, S.2
Koenen, M.3
Sakmann, B.4
-
29
-
-
0026656037
-
Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic
-
J.-L. Galzi, A. Devillers-Thiery, N. Hussy, S. Bertrand, J. P. Changeux, and D. Bertrand, "Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic," Nature, vol. 359, pp. 500-505, 1992.
-
(1992)
Nature
, vol.359
, pp. 500-505
-
-
Galzi, J.-L.1
Devillers-Thiery, A.2
Hussy, N.3
Bertrand, S.4
Changeux, J.P.5
Bertrand, D.6
-
30
-
-
0033119869
-
Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor
-
P. J. Corringer, S. Bertrand, J.-L. Galzi, A. Devillers-Thiery, J. P. Changeux, and D. Bertrand, "Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor," Neuron, vol. 22, pp. 831-843, 1999.
-
(1999)
Neuron
, vol.22
, pp. 831-843
-
-
Corringer, P.J.1
Bertrand, S.2
Galzi, J.-L.3
Devillers-Thiery, A.4
Changeux, J.P.5
Bertrand, D.6
-
31
-
-
0033916254
-
M2 pore mutations convert the glycine receptor channel from being anion- To cation-selective
-
A. Keramidas, A. J. Moorhouse, C. R. French, P. R. Schofield, and P. H. Barry, "M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective," Biophys. J., vol. 79, pp. 247-259, 2000.
-
(2000)
Biophys. J.
, vol.79
, pp. 247-259
-
-
Keramidas, A.1
Moorhouse, A.J.2
French, C.R.3
Schofield, P.R.4
Barry, P.H.5
-
32
-
-
0035999831
-
Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity
-
A. Keramidas, A. J. Moorhouse, K. D. Pierce, P. R. Schofield, and P. H. Barry, "Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity," J. Gen. Physiol., vol. 119, pp. 393-410, 2002.
-
(2002)
J. Gen. Physiol.
, vol.119
, pp. 393-410
-
-
Keramidas, A.1
Moorhouse, A.J.2
Pierce, K.D.3
Schofield, P.R.4
Barry, P.H.5
-
33
-
-
0242416182
-
The contribution of proline 250 (P-2′) to pore diameter and ion selectivity in the human glycine receptor channel
-
D. J.-S. Lee, A. Keramidas, A. J. Moorhouse, P. R. Schofield, and P. H. Barry, "The contribution of proline 250 (P-2′) to pore diameter and ion selectivity in the human glycine receptor channel," Neurosci. Lett., vol. 351, pp. 196-200, 2003.
-
(2003)
Neurosci. Lett.
, vol.351
, pp. 196-200
-
-
Lee, D.J.-S.1
Keramidas, A.2
Moorhouse, A.J.3
Schofield, P.R.4
Barry, P.H.5
-
34
-
-
0035815730
-
Conversion of the ion selectivity of the 5-HT(3A) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily
-
M. J. Gunthorpe and S. C. Lummis, "Conversion of the ion selectivity of the 5-HT(3A) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily," J. Biol. Chem., vol. 276, pp. 10977-10983, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10977-10983
-
-
Gunthorpe, M.J.1
Lummis, S.C.2
-
35
-
-
0038069026
-
Mutations at the GABA receptor selectivity filter: A possible role for effective charges
-
V. E. Wotring, T. S. Miller, and D. S. Weiss, "Mutations at the GABA receptor selectivity filter: a possible role for effective charges," J. Physiol., vol. 548, pp. 527-540, 2003.
-
(2003)
J. Physiol.
, vol.548
, pp. 527-540
-
-
Wotring, V.E.1
Miller, T.S.2
Weiss, D.S.3
-
36
-
-
11144230053
-
Charged residues at the 2′ position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability
-
J. E. Carland, A. J. Moorhouse, P. H. Barry, G. A. Johnston, and M. Chebib, "Charged residues at the 2′ position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability," J. Biol. Chem., vol. 279, pp. 54 153-54 160, 2004.
-
(2004)
J. Biol. Chem.
, vol.279
-
-
Carland, J.E.1
Moorhouse, A.J.2
Barry, P.H.3
Johnston, G.A.4
Chebib, M.5
-
37
-
-
0242349200
-
A model of the glycine receptor deduced from Brownian dynamics studies
-
M. O'Mara, P. H. Barry, and S. H. Chung, "A model of the glycine receptor deduced from Brownian dynamics studies," Proc. Nat. Acad. Sci. USA, vol. 100, pp. 4310-4315, 2003.
-
(2003)
Proc. Nat. Acad. Sci. USA
, vol.100
, pp. 4310-4315
-
-
O'Mara, M.1
Barry, P.H.2
Chung, S.H.3
-
38
-
-
0032215090
-
Allosteric receptors after 30 years
-
J. P. Changeux and S. J. Edelstein, "Allosteric receptors after 30 years," Neuron, vol. 21, pp. 959-980, 1998.
-
(1998)
Neuron
, vol.21
, pp. 959-980
-
-
Changeux, J.P.1
Edelstein, S.J.2
-
39
-
-
0013863816
-
Comparison of experimental binding data and theoretical models in proteins containing subunits
-
D. E. Koshland Jr., G. Nemethy, and D. Filmer, "Comparison of experimental binding data and theoretical models in proteins containing subunits," Biochemistry, vol. 5, pp. 365-385, 1966.
-
(1966)
Biochemistry
, vol.5
, pp. 365-385
-
-
Koshland Jr., D.E.1
Nemethy, G.2
Filmer, D.3
-
40
-
-
0038149197
-
Life at the top: The transition state of AChR gating
-
A. Auerbach, "Life at the top: the transition state of AChR gating," Sci. STKE, vol. 2003, p. re11, 2003.
-
(2003)
Sci. STKE
, vol.2003
-
-
Auerbach, A.1
-
41
-
-
2542432136
-
Cys-loop receptors: New twists and turns
-
H. A. Lester, M. I. Dibas, D. S. Dahan, J. F. Leite, and D. A. Dougherty, "Cys-loop receptors: new twists and turns," Trends Neurosci., vol. 27, pp. 329-336, 2004.
-
(2004)
Trends Neurosci.
, vol.27
, pp. 329-336
-
-
Lester, H.A.1
Dibas, M.I.2
Dahan, D.S.3
Leite, J.F.4
Dougherty, D.A.5
-
42
-
-
0032514762
-
From ab initio quantum mechanics to molecular neurobiology: A cation-pi binding site in the nicotinic receptor
-
W. Zhong, J. P. Gallivan, Y. Zhang, L. Li, H. A. Lester, and D. A. Dougherty, "From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor," Proc. Nat. Acad. Sci. USA, vol. 95, pp. 12088-12093, 1998.
-
(1998)
Proc. Nat. Acad. Sci. USA
, vol.95
, pp. 12088-12093
-
-
Zhong, W.1
Gallivan, J.P.2
Zhang, Y.3
Li, L.4
Lester, H.A.5
Dougherty, D.A.6
-
43
-
-
1842475289
-
Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures
-
P. H. Celie, S. E. van Rossum-Fikkert, W. J. van Dijk, K. Brejc, A. B. Smit, and T. K. Sixma, "Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures," Neuron, vol. 41, pp. 907-914, 2004.
-
(2004)
Neuron
, vol.41
, pp. 907-914
-
-
Celie, P.H.1
Van Rossum-Fikkert, S.E.2
Van Dijk, W.J.3
Brejc, K.4
Smit, A.B.5
Sixma, T.K.6
-
44
-
-
0028921479
-
Acetylcholine receptor channel imaged in the open state
-
N. Unwin, "Acetylcholine receptor channel imaged in the open state," Nature, vol. 373, pp. 37-43, 1995.
-
(1995)
Nature
, vol.373
, pp. 37-43
-
-
Unwin, N.1
-
45
-
-
0036304564
-
Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits
-
N. Unwin, A. Miyazawa, J. Li, and Y. Fujiyoshi, "Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits," J. Mol. Biol., vol. 319, pp. 1165-1176, 2002.
-
(2002)
J. Mol. Biol.
, vol.319
, pp. 1165-1176
-
-
Unwin, N.1
Miyazawa, A.2
Li, J.3
Fujiyoshi, Y.4
-
46
-
-
0035141668
-
Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation
-
D. A. Wagner and C. Czajkowski, "Structure and dynamics of the GABA binding pocket: a narrowing cleft that constricts during activation," J. Neurosci., vol. 21, pp. 67-74, 2001.
-
(2001)
J. Neurosci.
, vol.21
, pp. 67-74
-
-
Wagner, D.A.1
Czajkowski, C.2
-
47
-
-
0037544107
-
An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors
-
T. Grutter, L. Prado de Carvalho, N. Le Novere, P. J. Corringer, S. Edelstein, and J. P. Changeux, "An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors," EMBO J., vol. 22, pp. 1990-2003, 2003.
-
(2003)
EMBO J.
, vol.22
, pp. 1990-2003
-
-
Grutter, T.1
Prado De Carvalho, L.2
Le Novere, N.3
Corringer, P.J.4
Edelstein, S.5
Changeux, J.P.6
-
48
-
-
0031027684
-
Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel
-
J. W. Lynch, S. Rajendra, K. D. Pierce, C. A. Handford, P. H. Barry, and P. R. Schofield, "Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel," EMBO J., vol. 16, pp. 110-120, 1997.
-
(1997)
EMBO J.
, vol.16
, pp. 110-120
-
-
Lynch, J.W.1
Rajendra, S.2
Pierce, K.D.3
Handford, C.A.4
Barry, P.H.5
Schofield, P.R.6
-
49
-
-
0347379903
-
Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor
-
N. L. Absalom, T. M. Lewis, W. Kaplan, K. D. Pierce, and P. R. Schofield, "Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor," J. Biol Chem., vol. 278, pp. 50151-50157, 2003.
-
(2003)
J. Biol Chem.
, vol.278
, pp. 50151-50157
-
-
Absalom, N.L.1
Lewis, T.M.2
Kaplan, W.3
Pierce, K.D.4
Schofield, P.R.5
-
50
-
-
0037448581
-
Coupling of agonist binding to channel gating in the GABA(A) receptor
-
T. L. Kash, A. Jenkins, J. C. Kelley, J. R. Trudell, and N. L. Harrison, "Coupling of agonist binding to channel gating in the GABA(A) receptor," Nature, vol. 421, pp. 272-275, 2003.
-
(2003)
Nature
, vol.421
, pp. 272-275
-
-
Kash, T.L.1
Jenkins, A.2
Kelley, J.C.3
Trudell, J.R.4
Harrison, N.L.5
-
51
-
-
1042301377
-
Charged residues in the beta2 subunit involved in GABAA receptor activation
-
T. L. Kash, M. J. Dizon, J. R. Trudell, and N. L. Harrison, "Charged residues in the beta2 subunit involved in GABAA receptor activation," J. Biol. Chem., vol. 279, pp. 4887-4893, 2004.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4887-4893
-
-
Kash, T.L.1
Dizon, M.J.2
Trudell, J.R.3
Harrison, N.L.4
-
52
-
-
0029163027
-
Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors
-
C. Labarca, M. W. Nowak, H. Zhang, L. Tang, P. Deshpande, and H. A. Lester, "Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors," Nature, vol. 376, pp. 514-516, 1995.
-
(1995)
Nature
, vol.376
, pp. 514-516
-
-
Labarca, C.1
Nowak, M.W.2
Zhang, H.3
Tang, L.4
Deshpande, P.5
Lester, H.A.6
-
53
-
-
1642565156
-
Loose protein packing around the extracellular half of the GABA(A) receptor beta1 subunit M2 channel-lining segment
-
E. N. Goren, D. C. Reeves, and M. H. Akabas, "Loose protein packing around the extracellular half of the GABA(A) receptor beta1 subunit M2 channel-lining segment," J. Biol. Chem., vol. 279, pp. 11198-11205, 2004.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 11198-11205
-
-
Goren, E.N.1
Reeves, D.C.2
Akabas, M.H.3
-
54
-
-
0035042719
-
Protein mobility and GABA-induced conformational changes in GABA(A) receptor pore-lining M2 segment
-
J. Horenstein, D. A. Wagner, C. Czajkowski, and M. H. Akabas, "Protein mobility and GABA-induced conformational changes in GABA(A) receptor pore-lining M2 segment," Nature Neurosci., vol. 4, pp. 477-485, 2001.
-
(2001)
Nature Neurosci.
, vol.4
, pp. 477-485
-
-
Horenstein, J.1
Wagner, D.A.2
Czajkowski, C.3
Akabas, M.H.4
-
55
-
-
4143126482
-
A model of the closed form of the nicotinic acetylcholine receptor m2 channel pore
-
S. Kim, A. K. Chamberlain, and J. U. Bowie, "A model of the closed form of the nicotinic acetylcholine receptor m2 channel pore," Biophys. J., vol. 87, pp. 792-799, 2004.
-
(2004)
Biophys. J.
, vol.87
, pp. 792-799
-
-
Kim, S.1
Chamberlain, A.K.2
Bowie, J.U.3
-
56
-
-
0036522962
-
Evidence for a centrally located gate in the pore of a serotonin-gated ion channel
-
S. Panicker, H. Cruz, C. Arrabit, and P. A. Slesinger, "Evidence for a centrally located gate in the pore of a serotonin-gated ion channel," J. Neurosci., vol. 22, pp. 1629-1639, 2002.
-
(2002)
J. Neurosci.
, vol.22
, pp. 1629-1639
-
-
Panicker, S.1
Cruz, H.2
Arrabit, C.3
Slesinger, P.A.4
-
57
-
-
0027987062
-
Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit
-
M. H. Akabas, C. Kaufmann, P. Archdeacon, and A. Karlin, "Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit," Neuron, vol. 13, pp. 919-927, 1994.
-
(1994)
Neuron
, vol.13
, pp. 919-927
-
-
Akabas, M.H.1
Kaufmann, C.2
Archdeacon, P.3
Karlin, A.4
-
58
-
-
2442682764
-
Evidence that the TM1-TM2 to the rho1 GABA receptor pore
-
N. Filippova, V. E. Wotring, and D. S. Weiss, "Evidence that the TM1-TM2 to the rho1 GABA receptor pore," J. Biol. Chem., vol. 279, pp. 20906-20914, 2004.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20906-20914
-
-
Filippova, N.1
Wotring, V.E.2
Weiss, D.S.3
-
59
-
-
0029865892
-
Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit
-
M. Xu and M. H. Akabas, "Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit," J. Gen. Physiol., vol. 107, pp. 195-205, 1996.
-
(1996)
J. Gen. Physiol.
, vol.107
, pp. 195-205
-
-
Xu, M.1
Akabas, M.H.2
-
60
-
-
0032102496
-
The location of the gate in the acetylcholine receptor channel
-
G. G. Wilson and A. Karlin, "The location of the gate in the acetylcholine receptor channel," Neuron, vol. 20, pp. 1269-1281, 1998.
-
(1998)
Neuron
, vol.20
, pp. 1269-1281
-
-
Wilson, G.G.1
Karlin, A.2
-
61
-
-
0037389775
-
Structural effects of quinacrine binding in the open channel of the acetylcholine receptor
-
Y. Yu, L. Shi, and A. Karlin, "Structural effects of quinacrine binding in the open channel of the acetylcholine receptor," Proc. Nat. Acad. Sci. USA, vol. 100, pp. 3907-3912, 2003.
-
(2003)
Proc. Nat. Acad. Sci. USA
, vol.100
, pp. 3907-3912
-
-
Yu, Y.1
Shi, L.2
Karlin, A.3
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