Oral administration of second-generation immunomodulatory oligonucleotides induces mucosal Th1 immune responses and adjuvant activity

Vaccine

Volumn 23, Issue 20, 2005, Pages 2614-2622

  Wang, Daqing ^a   Kandimalla, Ekambar R ^a   Yu, Dong ^a   Tang, Jimmy X ^a   Agrawal, Sudhir ^a  

^a HYBRIDON INC   (United States)

Author keywords

CpG motif; Immunomodulatory oligonucleotides; Mucosal immune responses; Oral administration; Th1 cytokines

Indexed keywords

DNA VACCINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOLOGICAL ADJUVANT; IMMUNOMODULATING AGENT; IMMUNOMODULATORY OLIGONUCLEOTIDE 1 VACCINE; IMMUNOMODULATORY OLIGONUCLEOTIDE 2 VACCINE; IMMUNOMODULATORY OLIGONUCLEOTIDE 3 VACCINE; INTERLEUKIN 12; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; OVALBUMIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CPG ISLAND; CYTOKINE PRODUCTION; DRUG STABILITY; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; INTESTINE MUCOSA; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; TH1 CELL; TISSUE LEVEL;

EID: 15044356671     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2004.11.028     Document Type: Article

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