In vivo metabolic profile of a phosphorothioate oligodeoxyribonucleotide

Antisense and Nucleic Acid Drug Development

Volumn 7, Issue 3, 1997, Pages 159-165

  Temsamani, Jamal ^a   Roskey, Allysen ^a   Chaix, Carole ^a,b   Agrawal, Sudhir ^a  

^a HYBRIDON INC   (United States)

^b UNIVERSITÉ DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; GAG PROTEIN; MESSENGER RNA; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; TRECOVIRSEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; DNA DEGRADATION; DNA METABOLISM; DNA SEQUENCE; DRUG BLOOD LEVEL; DRUG DEGRADATION; DRUG DETERMINATION; DRUG LIVER LEVEL; DRUG METABOLISM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECOMBINANT PLASMID; VIRUS GENE;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030810546     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1997.7.159     Document Type: Article

References (6)

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4. AGRAWAL, S., and TEMSAMANI, J. (1996). Comparative pharmacokinetics of antisense oligonucleotides. In: Methods in Molecular Medicine: Antisense Therapeutics. S. Agrawal, ed. (Humana Press, Totowa, NJ), pp. 247-270.
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