Site of chemical modifications in CpG containing phosphorothioate oligodeoxynucleotide modulates its immunostimulatory activity

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 24, 1999, Pages 3453-3458

  Zhao, Qiuyan ^a   Yu, Dong ^a   Agrawal, Sudhir ^a  

^a HYBRIDON INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOSTIMULATING AGENT; NUCLEOSIDE DERIVATIVE; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHEMICAL MODIFICATION; DRUG SYNTHESIS; IMMUNOSTIMULATION; IN VIVO STUDY; LYMPHOCYTE; MOUSE; NONHUMAN; REACTION ANALYSIS; SPLEEN;

EID: 0033590264     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-894x(99)00635-6     Document Type: Article

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21. 2 laser. Molecular weight observed and calculated (in brackets) for each oligonucelotide were as follows: Oligo 1, 6041, (6043); Oligo 2, 6103, (6103); Oligo 3, 6091, (6089); Oligo 4, 6091, (6089); Oligo 5, 6105, (6103); Oligo 6, 6075, (6075); Oligo 7, 6087, (6089); Oligo 8, 6102, (6103); Oligo 9, 6089, (6089); Oligo 10, 6090, (6089); Oligo 11, 6102, (6103); Oligo 12, 6151, (6149); Oligo 13, 6149, (6149); Oligo 14, 6181, (6209); Oligo 15, 6364, (6363); Oligo 16, 6410, (6409); Oligo 17, 6407, (6409); Oligo 18, 6458, (6455).
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