Endoproteolytic processing of integrin pro-α subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7

Biochemical Journal

Volumn 346, Issue 1, 2000, Pages 133-138

  Lissitzky, Jean Claude ^a   Luis, José ^a   Munzer, Jon Scott ^b   Benjannet, Suzanne ^b   Parat, Francis ^a   Chrétien, Michel ^b,c   Marvaldi, Jacques ^a   Seidah, Nabil Georges ^b  

^a AIX MARSEILLE UNIVERSITY   (France)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^c OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

Cellular expression; Integrin processing; Proteolytic cleavage; Vaccinia virus

Indexed keywords

AMINO ACID; DIPEPTIDYL CARBOXYPEPTIDASE; FURIN; INTEGRIN; PROTEIN SUBUNIT; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CALCIUM; FURIN; GENE EXPRESSION; HUMANS; HYDROLYSIS; INTEGRINS; KINETICS; MEMBRANE PROTEINS; MOLECULAR WEIGHT; PRECIPITIN TESTS; PROPROTEIN CONVERTASE 5; PROPROTEIN CONVERTASES; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY; SUBTILISINS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0034652182     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3460133     Document Type: Article

References (50)

1. 1 Seidah, N. G. and Chrétien, M. (1997) Curr. Opin. Biotechnol. 8, 602-507
2. 2 Seidah, N. G., Day, R., Marcinkiewicz, M. and Chrétien, M. (1998) Ann. N. Y. Acad. Sci. 839, 9-24
3. 3 Benjannet, S., Rondeau, N., Day, R., Chrétien, M. and Seidah, N. G. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 3564-3568
4. 4 Jones, B. G., Thomas, L., Molloy, S. S., Thulin, C. D., Fry, M. D., Walsh, K. A. and Thomas, G. (1995) EMBO J. 14, 5869-5883
5. 5 van de Loo, J. W., Creemers, J. W., Bright, N. A., Young, B. D., Roebroek, A. J. and Van de Yen, W. J. (1997) J. Biol. Chem. 272, 27116-27123
6. 6 Schafer, W., Stroh, A., Berghofer, S., Seiler, J., Vey, M., Kruse, M. L. Kern, H. F., Klenk, H. D. and Garten, W. (1995) EMBO J. 14, 2424-2435
7. 7 Takahashi, S., Nakagawa, T., Banno, T., Watanabe, T., Murakami, K. and Nakayama, K. (1995) J. Biol. Chem. 270, 28397-28401
8. 8 Seidah, N. G., Benjannet, S., Pareek, S., Savaria, D., Hamelin, J., Goulet, B., Laliberté, J., Lazure, C., Chrétien, M. and Murphy, R. A. (1996) Biochem. J. 314, 951-960
9. 9 Komada, M., Hatsuzawa, K., Shibamoto, S., Ito, F., Nakayama, K. and Kitamura, N. (1993) FEBS Lett. 328, 25-29
10. 10 Lehmann, M., Andre, F., Bellan, C., Remaclebonnet, M., Garrouste, F., Parat, F., Lissitsky, J. C., Marvaldi, J. and Pommier, G. (1998) Endocrinology (Baltimore) 139, 3763-3771
11. 11 Logeat, F., Bessia, C., Brou, C., Lebail, O., Jarriault, S., Seidah, N. G. and Israël, A. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 8108-8112
12. 12 Lonnqvist, L., Reinhardt, D., Sakai, L. and Peltonen, L. (1998) Hum. Mol. Genet. 7, 2039-2044
13. 13 Schacke, H., Schumann, H., Hammami-Hauasli, N., Raghunath, M. and Bruckner-Tuderman, L. (1998) J. Biol. Chem. 273, 25937-25943
14. 14 Santavicca, M., Noël, A., Angliker, H., Stoll, I., Segain, J. P., Anglard, P., Chrétien, M., Seidah, N. G. and Basset, P. (1996) Biochem. J. 315, 953-958
15. 15 Hubbard, F. C., Goodrow, T. L., Liu, S. C., Brilliant, M. H., Basset, P., Mains, R. E. and Kleinszanto, A. J. P. (1997) Cancer Res. 57, 5226-5231
16. 16 Decroly, E., Wouters, S., Dibello, C., Lazure, C. Ruysschaert, J. M. and Seidah, N. G. (1996) J. Biol. Chem. 271, 30442-30450
17. 17 Decroly, E., Benjannet, S., Savaria, D. and Seidah, N. G. (1997) FEBS Lett. 405, 68-72
18. 18 Hynes, R. O. (1987) Cell 48, 549-554
19. 19 Hynes, R. O. (1992) Cell 69, 11-25
20. 20 Aplin, A. E., Howe, A., Alahari, S. K. and Juliano, R. L. (1998) Pharmacol. Rev. 50, 197-263
21. 21 Delwel, G. O., Hogervorst, F. and Sonnenberg, A. (1996) J. Biol. Chem. 271, 7293-7296
22. 22 Takahashi, S., Nakagawa, T., Kasai, K., Banno, T., Duguay, S. J., Van de Ven, W., Murakami, K. and Nakayama, K. (1995) J. Biol. Chem. 270. 26565-26569
23. 23 Lehmann, M., Rigot, V., Seidah, N. G., Marvaldi, J. and Lissitzky, J. C. (1996) Biochem. J. 317, 803-809
24. 24 Molloy, S. S., Thomas, L., Vanslyke, J. K., Stenberg, P. E. and Thomas, G. (1994) EMBO J. 13, 18-33
25. 25 Apletalina, E., Appel, J., Lamango, N. S., Hoghten, R. A. and Lindberg, I. (1998) J. Biol. Chem. 273, 26589-26595
26. 26 Anderson, E. D., Thomas, L., Hayflick, J. S. and Thomas, G. (1993) J. Biol. Chem. 268, 24887-24891
27. 27 Benjannet, S., Savaria, D., Laslop, A., Munzer, J. S., Chrétien, M., Marcinkiewicz, M. and Seidah, N. G. (1997) J. Biol. Chem. 272, 26210-26218
28. 28 Rompaey, L. V., Ayoubi, T., Van de Ven, W. and Marynen, P. (1997) Biochem. J. 326, 507-514
29. 29 Boudreault, A., Gauthier, D. and Lazure, C. (1998) J. Biol. Chem. 273, 31574-31580
30. 30 Zhong, M., Munzer, J. S., Basak, A., Benjannet, S., Mowla, S. J., Decroly, E., Chrétien, M. and Seidah, N. G. (1999) J. Biol. Chem. 274, 33913-33920
31. 31 Rovère, C., Luis, J., Lissitzky, J. C., Basak, A., Marvaldi, J., Chrétien, M. and Seidah, N. G. (1999) J. Biol. Chem. 274, 12461-12467
32. 32 Munzer, J. S., Basak, A., Zhong, M., Mamarbachi, A., Hamelin, J., Savaria, D., Lazure, C., Benjannet, S., Chrétien, M. and Seidah, N. G. (1997) J. Biol. Chem. 272, 19672-19681
33. 33 Lehmann, M., Rabenandrasana, C., Tamura, R., Lissitzky, J. C., Quaranta, V., Pichon, J. and Marvaldi, J. (1994) Cancer Res. 54, 2102-2107
34. 34 Benjannet, S., Reudelhuber, T., Mercure, C., Rondeau, N., Chrétien, M. and Seidah, N. G. (1992) J. Biol. Chem. 267, 11417-11423
35. 35 Seidah, N. G., Chrétien, M. and Day, R. (1994) Biochimie 76, 197-209
36. 36 Vollenweider, F., Benjannet, S., Decroly, E., Savaria, D., Lazure, C., Thomas, G., Chrétien, M. and Seidah, N. G. (1996) Biochem. J. 314, 521-532
37. 37 Furuta, M., Yano, H., Zhou, A., Rouillé, Y., Holst, J. J., Carroll, R., Ravazzola, M., Orci, L., Furuta, H. and Steiner, D. F. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 6646-6651
38. 38 Delwel, G. O., Kuikman, I., van der Schors, R. C., de Melker, A. A. and Sonnenberg, A. (1997) Biochem. J. 324, 263-272
39. 39 Campan, M., Yoshizumi, M., Seidah, N. G., Lee, M. E., Bianchi, C. and Haber, E. (1996) Biochemistry 35, 3797-3802
40. 40 De Bie, I., Marcinkiewicz, M., Malide, D., Lazure, C., Nakayama, K., Bendayan, M and Seidah, N. G. (1996) J. Cell Biol 135, 1261-1275
41. 41 Barbero, P., Rovère, C., De Bie, I., Seidah, N. G., Beaudet, A. and Kitabgi, P. (1998) J. Biol. Chem. 273, 25339-25346
42. 42 Nachtigal, M. W. and Ingraham, H. A. (1996) Proc. Natl. Acad. Sci. U.S.A. 93 7711-7716
43. 43 Posthaus, H., Dubois, C. M., Laprise, M. H., Grondin, F., Suter, M. M. and Muller, E. (1998) FEBS Lett. 438, 306-310
44. 44 Beaubien, G., Schafer, M. K. H., Weihe, E., Dong, W. J., Chrétien, M., Seidah, N. G. and Day, R. (1995) Cell Tiss. Res. 279, 539-549
45. 45 Hoshiga, M., Alpers, C. E., Smith, L. L., Giachelli, C. M. and Schwartz, S. M. (1995) Circ. Res. 77, 1129-1135
46. 46 Horton, M. A. (1997) Int. J. Biochem. Cell Biol. 29, 721-725
47. 47 Brooks, P. C., Clark, R. A. and Cheresh, D. A. (1994) Science 264, 569-571
48. 48 Brown, S. L., Lundgren, C. H., Nordt, T. and Fujii, S. (1994) Cardiovasc. Res. 28, 1815-1820
49. 49 Jean, F., Stella, K., Thomas, L. Liu, G. P., Xiang, Y., Reason, A. J. and Thomas, G. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 7293-7298
50. 50 Wouters, S., Leruth, M., Decroly, E., Vandenbranden, M., Creerners, J. W., van de Loo, J. W., Ruysschaert, J. M. and Courtoy, P. J. (1998) Biochem. J. 336, 311-316