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Volumn 19, Issue 3, 2005, Pages 331-341

Antibody phage display technologies with special reference to angiogenesis

Author keywords

Angiogenic therapy; CD105; Vascular targeting; Vasculogenesis; VEGF

Indexed keywords

ANGIOGENESIS INHIBITOR; AUTOANTIBODY; BASIC FIBROBLAST GROWTH FACTOR; CELL MARKER; CILENGITIDE; ENDOGLIN; FIBRONECTIN; IMMUNOSUPPRESSIVE AGENT; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD105; MONOCLONAL ANTIBODY LM 609; PLATELET DERIVED GROWTH FACTOR; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2;

EID: 14644436317     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.04-2863rev     Document Type: Review
Times cited : (28)

References (107)
  • 1
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman, J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1, 27-31
    • (1995) Nat. Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 2
    • 0032705201 scopus 로고    scopus 로고
    • New vessels, new approaches: Angiogenesis as a therapeutic target in musculoskeletal disorders
    • Ballara, S. C., Miotla, J. M., and Paleolog, E. M. (1999) New vessels, new approaches: angiogenesis as a therapeutic target in musculoskeletal disorders. Int. J. Exp. Pathol. 80, 235-250
    • (1999) Int. J. Exp. Pathol. , vol.80 , pp. 235-250
    • Ballara, S.C.1    Miotla, J.M.2    Paleolog, E.M.3
  • 3
    • 0038725471 scopus 로고    scopus 로고
    • CD105 is important for angiogenesis: Evidence and potential applications
    • Duff, S. E., Li, C., Garland, J. M., and Kumar, S. (2003) CD105 is important for angiogenesis: evidence and potential applications. FASEB J. 17, 984-992
    • (2003) FASEB J. , vol.17 , pp. 984-992
    • Duff, S.E.1    Li, C.2    Garland, J.M.3    Kumar, S.4
  • 4
    • 0037235949 scopus 로고    scopus 로고
    • Engineered antibodies
    • Hudson, P. J., and Souriau, C. (2003) Engineered antibodies. Nat. Med. 9, 129-134
    • (2003) Nat. Med. , vol.9 , pp. 129-134
    • Hudson, P.J.1    Souriau, C.2
  • 5
    • 1242340428 scopus 로고    scopus 로고
    • Antiangiogenic cancer therapy
    • Cao, Y. (2004) Antiangiogenic cancer therapy. Semin. Cancer Biol. 14, 139-145
    • (2004) Semin. Cancer Biol. , vol.14 , pp. 139-145
    • Cao, Y.1
  • 6
    • 0026362940 scopus 로고
    • Switch to the angiogenic phenotype during tumorigenesis
    • Folkman, J., and Hanahan, D. (1991) Switch to the angiogenic phenotype during tumorigenesis. Princess Takamatsu Symp. 22, 339-347
    • (1991) Princess Takamatsu Symp. , vol.22 , pp. 339-347
    • Folkman, J.1    Hanahan, D.2
  • 7
    • 1542516508 scopus 로고    scopus 로고
    • Therapeutic angiogenesis. Devising new strategies based on past experiences
    • Lei, Y., Haider, H. K., Shujia, J., and Sim, E. S. (2004) Therapeutic angiogenesis. Devising new strategies based on past experiences. Basic Res. Cardiol. 99, 121-132
    • (2004) Basic Res. Cardiol. , vol.99 , pp. 121-132
    • Lei, Y.1    Haider, H.K.2    Shujia, J.3    Sim, E.S.4
  • 8
    • 0028873980 scopus 로고
    • Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity diabetic ulcers
    • Diabetic Ulcer Study Group
    • Steed, D. L. (1995) Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity diabetic ulcers. Diabetic Ulcer Study Group. J Vasc. Surg. 21, 71-78
    • (1995) J Vasc. Surg. , vol.21 , pp. 71-78
    • Steed, D.L.1
  • 11
    • 0034033152 scopus 로고    scopus 로고
    • Enhancement of angiogenesis by the implantation of self bone marrow cells in a rat ischemic heart model
    • Kobayashi, T., Hamano, K., Li, T. S., Katoh, T., Kobayashi, S., Matsuzaki, M., and Esato, K. (2000) Enhancement of angiogenesis by the implantation of self bone marrow cells in a rat ischemic heart model. J. Surg. Res. 89, 189-195
    • (2000) J. Surg. Res. , vol.89 , pp. 189-195
    • Kobayashi, T.1    Hamano, K.2    Li, T.S.3    Katoh, T.4    Kobayashi, S.5    Matsuzaki, M.6    Esato, K.7
  • 12
    • 0344304667 scopus 로고    scopus 로고
    • Stem cell-derived angiogenic/vasculogenic cells: Possible therapies for tissue repair and tissue engineering
    • Zwaginga, J. J., and Doevendans, P. (2003) Stem cell-derived angiogenic/vasculogenic cells: possible therapies for tissue repair and tissue engineering. Clin. Exp. Pharmacol. Physiol. 30, 900-908
    • (2003) Clin. Exp. Pharmacol. Physiol. , vol.30 , pp. 900-908
    • Zwaginga, J.J.1    Doevendans, P.2
  • 13
    • 0034060755 scopus 로고    scopus 로고
    • Imaging of tumour neovasculature by targeting the TGF-beta binding receptor endoglin
    • Bredow, S., Lewin, M., Hofmann, B., Marecos, E., and Weissleder, R. (2000) Imaging of tumour neovasculature by targeting the TGF-beta binding receptor endoglin. Eur. J. Cancer 36, 675-681
    • (2000) Eur. J. Cancer , vol.36 , pp. 675-681
    • Bredow, S.1    Lewin, M.2    Hofmann, B.3    Marecos, E.4    Weissleder, R.5
  • 14
    • 0030006897 scopus 로고    scopus 로고
    • Intratumoral blood flow in uterine myoma correlated with a lower tumor size and volume, but not correlated with cell proliferation or angiogenesis
    • Huang, S. C., Yu, C. H., Huang, R. T., Hsu, K. F., Tsai, Y. C., and Chou, C. Y. (1996) Intratumoral blood flow in uterine myoma correlated with a lower tumor size and volume, but not correlated with cell proliferation or angiogenesis. Obstet. Gynecol. 87, 1019-1024
    • (1996) Obstet. Gynecol. , vol.87 , pp. 1019-1024
    • Huang, S.C.1    Yu, C.H.2    Huang, R.T.3    Hsu, K.F.4    Tsai, Y.C.5    Chou, C.Y.6
  • 15
    • 0032171619 scopus 로고    scopus 로고
    • Rocking the foundations of solid tumor growth by attacking the tumor's blood supply
    • Molema, G., and Griffioen, A. W. (1998) Rocking the foundations of solid tumor growth by attacking the tumor's blood supply. Immunol. Today 19, 392-394
    • (1998) Immunol. Today , vol.19 , pp. 392-394
    • Molema, G.1    Griffioen, A.W.2
  • 16
    • 0032532656 scopus 로고    scopus 로고
    • Infarction of solid Hodgkin's tumors in mice by antibody-directed targeting of tissue factor to tumor vasculature
    • Ran, S., Gao, B., Duffy, S., Watkins, L., Rote, N., and Thorpe, P. E. (1998) Infarction of solid Hodgkin's tumors in mice by antibody-directed targeting of tissue factor to tumor vasculature. Cancer Res. 58, 4646-4653
    • (1998) Cancer Res. , vol.58 , pp. 4646-4653
    • Ran, S.1    Gao, B.2    Duffy, S.3    Watkins, L.4    Rote, N.5    Thorpe, P.E.6
  • 17
    • 0033573982 scopus 로고    scopus 로고
    • Synergy between an antiangiogenic integrin alphav antagonist and an antibody-cytokine fusion protein eradicates spontaneous tumor metastases
    • Lode, H. N., Moehler, T., Xiang, R., Jonczyk, A., Gillies, S. D., Cheresh, D. A., and Reisfeld, R. A. (1999) Synergy between an antiangiogenic integrin alphav antagonist and an antibody-cytokine fusion protein eradicates spontaneous tumor metastases. Proc. Natl. Acad. Sci. USA 96, 1591-1596
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 1591-1596
    • Lode, H.N.1    Moehler, T.2    Xiang, R.3    Jonczyk, A.4    Gillies, S.D.5    Cheresh, D.A.6    Reisfeld, R.A.7
  • 18
    • 0042165831 scopus 로고    scopus 로고
    • Alpha v integrin inhibitors and cancer therapy
    • Tucker, G. C. (2003) Alpha v integrin inhibitors and cancer therapy. Curr. Opin. Investig. Drugs 4, 722-731
    • (2003) Curr. Opin. Investig. Drugs , vol.4 , pp. 722-731
    • Tucker, G.C.1
  • 19
    • 0032893957 scopus 로고    scopus 로고
    • Decreased angiogenesis and arthritic disease in rabbits treated with an alphavbeta3 antagonist
    • Storgard, C. M., Stupack, D. G., Jonczyk, A., Goodman, S. L., Fox, R. I., and Cheresh, D. A. (1999) Decreased angiogenesis and arthritic disease in rabbits treated with an alphavbeta3 antagonist. J. Clin. Invest. 103, 47-54
    • (1999) J. Clin. Invest. , vol.103 , pp. 47-54
    • Storgard, C.M.1    Stupack, D.G.2    Jonczyk, A.3    Goodman, S.L.4    Fox, R.I.5    Cheresh, D.A.6
  • 21
    • 0037105721 scopus 로고    scopus 로고
    • Significance of blood vessel leakiness in cancer
    • McDonald, D. M., and Baluk, P. (2002) Significance of blood vessel leakiness in cancer. Cancer Res. 62, 5381-5385
    • (2002) Cancer Res. , vol.62 , pp. 5381-5385
    • McDonald, D.M.1    Baluk, P.2
  • 22
    • 0032578961 scopus 로고    scopus 로고
    • Gene therapy for myocardial angiogenesis: Initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia
    • Losordo, D. W., Vale, P. R., Symes, J. F., Dunnington, C. H., Esakof, D. D., Maysky, M., Ashare, A. B., Lathi, K., and Isner, J. M. (1998) Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. Circulation 98, 2800-2804
    • (1998) Circulation , vol.98 , pp. 2800-2804
    • Losordo, D.W.1    Vale, P.R.2    Symes, J.F.3    Dunnington, C.H.4    Esakof, D.D.5    Maysky, M.6    Ashare, A.B.7    Lathi, K.8    Isner, J.M.9
  • 23
    • 0033033210 scopus 로고    scopus 로고
    • Therapeutic angiogenesis
    • Henry, T. D. (1999) Therapeutic angiogenesis. BMJ 318, 1536-1539
    • (1999) BMJ , vol.318 , pp. 1536-1539
    • Henry, T.D.1
  • 25
    • 0032997008 scopus 로고    scopus 로고
    • The clinical manipulation of angiogenesis: Pathology, side effects, surprises, and opportunities with novel human therapies
    • Thompson, W. D., Li, W. W., and Maragoudakis, M. (1999) The clinical manipulation of angiogenesis: pathology, side effects, surprises, and opportunities with novel human therapies. J. Pathol. 187, 503-510
    • (1999) J. Pathol. , vol.187 , pp. 503-510
    • Thompson, W.D.1    Li, W.W.2    Maragoudakis, M.3
  • 27
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Kohler, G., and Milstein, C. (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature (London) 256, 495-497
    • (1975) Nature (London) , vol.256 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 28
    • 0031449358 scopus 로고    scopus 로고
    • FcRn: The MHC class I-related receptor that is more than an IgG transporter
    • Ghetie, V., and Ward, E. S. (1997) FcRn: the MHC class I-related receptor that is more than an IgG transporter. Immunol. Today 18, 592-598
    • (1997) Immunol. Today , vol.18 , pp. 592-598
    • Ghetie, V.1    Ward, E.S.2
  • 29
    • 0141758337 scopus 로고    scopus 로고
    • New technologies in therapeutic antibody development
    • Brekke, O. H., and Loset, G. A. (2003) New technologies in therapeutic antibody development. Curr. Opin. Pharmacol. 3, 544-550
    • (2003) Curr. Opin. Pharmacol. , vol.3 , pp. 544-550
    • Brekke, O.H.1    Loset, G.A.2
  • 30
    • 0033855859 scopus 로고    scopus 로고
    • Clinical trials of antibody therapy
    • Glennie, M. J., and Johnson, P. W. (2000) Clinical trials of antibody therapy. Immunol. Today 21, 403-410
    • (2000) Immunol. Today , vol.21 , pp. 403-410
    • Glennie, M.J.1    Johnson, P.W.2
  • 31
    • 0032872567 scopus 로고    scopus 로고
    • Monoclonal antibody drug conjugates in the treatment of cancer
    • Trail, P. A., and Bianchi, A. B. (1999) Monoclonal antibody drug conjugates in the treatment of cancer. Curr. Opin. Immunol. 11, 584-588
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 584-588
    • Trail, P.A.1    Bianchi, A.B.2
  • 32
    • 0029143898 scopus 로고
    • Treatment of active refractory rheumatoid arthritis with humanized monoclonal antibody CAMPATH-1H administered by daily subcutaneous injection
    • Matteson, E. L., Yocum, D. E., St Clair, E. W., Achkar, A. A., Thakor, M. S., Jacobs, M. R., Hays, A. E., Heitman, C. K., and Johnston, J. M. (1995) Treatment of active refractory rheumatoid arthritis with humanized monoclonal antibody CAMPATH-1H administered by daily subcutaneous injection. Arthritis Rheum. 38, 1187-1193
    • (1995) Arthritis Rheum. , vol.38 , pp. 1187-1193
    • Matteson, E.L.1    Yocum, D.E.2    St Clair, E.W.3    Achkar, A.A.4    Thakor, M.S.5    Jacobs, M.R.6    Hays, A.E.7    Heitman, C.K.8    Johnston, J.M.9
  • 33
    • 0033506131 scopus 로고    scopus 로고
    • Generating improved single-chain Fv molecules for tumor targeting
    • Adams, G. P., and Schier, R. (1999) Generating improved single-chain Fv molecules for tumor targeting. J. Immunol. Methods 231, 249-260
    • (1999) J. Immunol. Methods , vol.231 , pp. 249-260
    • Adams, G.P.1    Schier, R.2
  • 34
    • 0345504113 scopus 로고    scopus 로고
    • Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: A comparison of conjugation chemistries and compounds
    • Lee, L. S., Conover, C., Shi, C., Whitlow, M., and Filpula, D. (1999) Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: a comparison of conjugation chemistries and compounds. Bioconjug. Chem. 10, 973-981
    • (1999) Bioconjug. Chem. , vol.10 , pp. 973-981
    • Lee, L.S.1    Conover, C.2    Shi, C.3    Whitlow, M.4    Filpula, D.5
  • 36
    • 0033970095 scopus 로고    scopus 로고
    • New approaches for cell-specific targeting: Identification of cell-selective peptides from combinatorial libraries
    • Brown, K. C. (2000) New approaches for cell-specific targeting: identification of cell-selective peptides from combinatorial libraries. Curr. Opin. Chem. Biol. 4, 16-21
    • (2000) Curr. Opin. Chem. Biol. , vol.4 , pp. 16-21
    • Brown, K.C.1
  • 37
    • 0037379630 scopus 로고    scopus 로고
    • Phage display selection and evaluation of cancer drug targets
    • Romanov, V. I. (2003) Phage display selection and evaluation of cancer drug targets. Curr. Cancer Drug Targets 3, 119-129
    • (2003) Curr. Cancer Drug Targets , vol.3 , pp. 119-129
    • Romanov, V.I.1
  • 39
    • 0030803394 scopus 로고    scopus 로고
    • Comparison of fusion phage libraries displaying VH or single-chain Fv antibody fragments derived from the antibody repertoire of a vaccinated melanoma patient as a source of melanoma-specific targeting molecules
    • Cai, X., and Garen, A. (1997) Comparison of fusion phage libraries displaying VH or single-chain Fv antibody fragments derived from the antibody repertoire of a vaccinated melanoma patient as a source of melanoma-specific targeting molecules. Proc. Natl. Acad. Sci. USA 94, 9261-9266
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9261-9266
    • Cai, X.1    Garen, A.2
  • 40
    • 0031791593 scopus 로고    scopus 로고
    • A novel tumor-specific human single-chain Fv selected from an active specific immunotherapy phage display library
    • Hall, B. L., Boroughs, J., and Kobrin, B. J. (1998) A novel tumor-specific human single-chain Fv selected from an active specific immunotherapy phage display library. Immunotechnology 4, 127-140
    • (1998) Immunotechnology , vol.4 , pp. 127-140
    • Hall, B.L.1    Boroughs, J.2    Kobrin, B.J.3
  • 45
    • 0031081318 scopus 로고    scopus 로고
    • Designing and optimizing library selection strategies for generating high-affinity antibodies
    • Hoogenboom, H. R. (1997) Designing and optimizing library selection strategies for generating high-affinity antibodies. Trends Biotechnol. 15, 62-70
    • (1997) Trends Biotechnol. , vol.15 , pp. 62-70
    • Hoogenboom, H.R.1
  • 47
    • 0026938962 scopus 로고
    • Antibody expression in bacteriophage systems: The future of monoclonal antibodies?
    • Garrard, L. J., and Zhukovsky, E. A. (1992) Antibody expression in bacteriophage systems: the future of monoclonal antibodies? Curr. Opin. Biotechnol. 3, 474-480
    • (1992) Curr. Opin. Biotechnol. , vol.3 , pp. 474-480
    • Garrard, L.J.1    Zhukovsky, E.A.2
  • 48
    • 0029150047 scopus 로고
    • Domain libraries: Synthetic diversity for de novo design of antibody V-regions
    • Soderlind, E., Vergeles, M., and Borrebaeck, C. A. (1995) Domain libraries: synthetic diversity for de novo design of antibody V-regions. Gene 160, 269-272
    • (1995) Gene , vol.160 , pp. 269-272
    • Soderlind, E.1    Vergeles, M.2    Borrebaeck, C.A.3
  • 50
    • 0034635335 scopus 로고    scopus 로고
    • Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides
    • Knappik, A., Ge, L., Honegger, A., Pack, P., Fischer, M., Wellnhofer, G., Hoess, A., Wolle, J., Pluckthun, A., and Virnekas, B. (2000) Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides. J. Mol. Biol. 296, 57-86
    • (2000) J. Mol. Biol. , vol.296 , pp. 57-86
    • Knappik, A.1    Ge, L.2    Honegger, A.3    Pack, P.4    Fischer, M.5    Wellnhofer, G.6    Hoess, A.7    Wolle, J.8    Pluckthun, A.9    Virnekas, B.10
  • 51
    • 1842426593 scopus 로고    scopus 로고
    • Isolation of endothelial cell-specific human antibodies from a novel fully synthetic scFv library
    • Volkel, T., Muller, R., and Kontermann, R. E. (2004) Isolation of endothelial cell-specific human antibodies from a novel fully synthetic scFv library. Biochem. Biophys. Res. Commun. 317, 515-521
    • (2004) Biochem. Biophys. Res. Commun. , vol.317 , pp. 515-521
    • Volkel, T.1    Muller, R.2    Kontermann, R.E.3
  • 52
    • 0034244316 scopus 로고    scopus 로고
    • By-passing selection: Direct screening for antibody-antigen interactions using protein arrays
    • Holt, L. J., Bussow, K., Walter, G., and Tomlinson, I. M. (2000) By-passing selection: direct screening for antibody-antigen interactions using protein arrays. Nucleic Acids Res. 28, E72
    • (2000) Nucleic Acids Res. , vol.28
    • Holt, L.J.1    Bussow, K.2    Walter, G.3    Tomlinson, I.M.4
  • 53
    • 0036181477 scopus 로고    scopus 로고
    • Recombinant monoclonal antibody technology
    • Siegel, D. L. (2002) Recombinant monoclonal antibody technology. Transfus. Clin. Biol. 9, 15-22
    • (2002) Transfus. Clin. Biol. , vol.9 , pp. 15-22
    • Siegel, D.L.1
  • 56
    • 0033103199 scopus 로고    scopus 로고
    • Complementarity-determining region (CDR) implantation: A theme of recombination
    • Soderlind, E., Ohlin, M., and Carlsson, R. (1999) Complementarity- determining region (CDR) implantation: a theme of recombination. Immunotechnology 4, 279-285
    • (1999) Immunotechnology , vol.4 , pp. 279-285
    • Soderlind, E.1    Ohlin, M.2    Carlsson, R.3
  • 57
    • 0035558749 scopus 로고    scopus 로고
    • n-CoDeR concept: Unique types of antibodies for diagnostic use and therapy
    • Carlsson, R., and Soderlind, E. (2001) n-CoDeR concept: unique types of antibodies for diagnostic use and therapy. Expert Rev. Mol. Diagn. 1, 102-108
    • (2001) Expert Rev. Mol. Diagn. , vol.1 , pp. 102-108
    • Carlsson, R.1    Soderlind, E.2
  • 58
    • 0033584889 scopus 로고    scopus 로고
    • Selection for improved protein stability by phage display
    • Jung, S., Honegger, A., and Pluckthun, A. (1999) Selection for improved protein stability by phage display. J. Mol. Biol. 294, 163-180
    • (1999) J. Mol. Biol. , vol.294 , pp. 163-180
    • Jung, S.1    Honegger, A.2    Pluckthun, A.3
  • 59
    • 0029021085 scopus 로고
    • Anti-melanoma antibodies from melanoma patients immunized with genetically modified autologous tumor cells: Selection of specific antibodies from single-chain Fv fusion phage libraries
    • Cai, X., and Garen, A. (1995) Anti-melanoma antibodies from melanoma patients immunized with genetically modified autologous tumor cells: selection of specific antibodies from single-chain Fv fusion phage libraries. Proc. Natl. Acad. Sci. USA 92, 6537-6541
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 6537-6541
    • Cai, X.1    Garen, A.2
  • 61
    • 0036489777 scopus 로고    scopus 로고
    • Recombinant antibodies for the selective targeting of tumor neovasculature
    • Viti, F., Giovannoni, L., and Neri, D. (2002) Recombinant antibodies for the selective targeting of tumor neovasculature. Curr. Opin. Drug Discov. Dev. 5, 204-213
    • (2002) Curr. Opin. Drug Discov. Dev. , vol.5 , pp. 204-213
    • Viti, F.1    Giovannoni, L.2    Neri, D.3
  • 63
    • 0033507360 scopus 로고    scopus 로고
    • Phage antibodies against human dendritic cell subpopulations obtained by flow cytometry-based selection on freshly isolated cells
    • Lekkerkerker, A., and Logtenberg, T. (1999) Phage antibodies against human dendritic cell subpopulations obtained by flow cytometry-based selection on freshly isolated cells. J. Immunol. Methods 231, 53-63
    • (1999) J. Immunol. Methods , vol.231 , pp. 53-63
    • Lekkerkerker, A.1    Logtenberg, T.2
  • 64
  • 65
    • 0038746649 scopus 로고    scopus 로고
    • Use of a phage display library to identify oligopeptides binding to the lumenal surface of polarized endothelium by ex vivo perfusion of human umbilical veins
    • Maruta, F., Parker, A. L., Fisher, K. D., Murray, P. G., Kerr, D. J., and Seymour, L. W. (2003) Use of a phage display library to identify oligopeptides binding to the lumenal surface of polarized endothelium by ex vivo perfusion of human umbilical veins. J. Drug Target. 11, 53-59
    • (2003) J. Drug Target. , vol.11 , pp. 53-59
    • Maruta, F.1    Parker, A.L.2    Fisher, K.D.3    Murray, P.G.4    Kerr, D.J.5    Seymour, L.W.6
  • 67
    • 0031733866 scopus 로고    scopus 로고
    • Stabilizing the subtilisin BPN' pro-domain by phage display selection: How restrictive is the amino acid code for maximum protein stability?
    • Ruan, B., Hoskins, J., Wang, L., and Bryan, P. N. (1998) Stabilizing the subtilisin BPN' pro-domain by phage display selection: how restrictive is the amino acid code for maximum protein stability? Protein Sci. 7, 2345-2353
    • (1998) Protein Sci. , vol.7 , pp. 2345-2353
    • Ruan, B.1    Hoskins, J.2    Wang, L.3    Bryan, P.N.4
  • 68
    • 0031729179 scopus 로고    scopus 로고
    • Selecting proteins with improved stability by a phage-based method
    • Sieber, V., Pluckthun, A., and Schmid, F. X. (1998) Selecting proteins with improved stability by a phage-based method. Nat. Biotechnol. 16, 955-960
    • (1998) Nat. Biotechnol. , vol.16 , pp. 955-960
    • Sieber, V.1    Pluckthun, A.2    Schmid, F.X.3
  • 69
    • 0031979136 scopus 로고    scopus 로고
    • Improving the tumor specificity and retention of antibody-based molecules
    • Adams, G. P. (1998) Improving the tumor specificity and retention of antibody-based molecules. In Vivo 12, 11-21
    • (1998) In Vivo , vol.12 , pp. 11-21
    • Adams, G.P.1
  • 70
    • 0030575802 scopus 로고    scopus 로고
    • Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site
    • Schier, R., McCall, A., Adams, G. P., Marshall, K. W., Merritt, H., Yim, M., Crawford, R. S., Weiner, L. M., Marks, C., and Marks, J. D. (1996) Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site. J. Mol. Biol. 263, 551-567
    • (1996) J. Mol. Biol. , vol.263 , pp. 551-567
    • Schier, R.1    McCall, A.2    Adams, G.P.3    Marshall, K.W.4    Merritt, H.5    Yim, M.6    Crawford, R.S.7    Weiner, L.M.8    Marks, C.9    Marks, J.D.10
  • 71
    • 0242353266 scopus 로고    scopus 로고
    • Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity
    • Lu, D., Shen, J., Vil, M. D., Zhang, H., Jimenez, X., Bohlen, P., Witte, L., and Zhu, Z. (2003) Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity. J. Biol. Chem. 278, 43496-43507
    • (2003) J. Biol. Chem. , vol.278 , pp. 43496-43507
    • Lu, D.1    Shen, J.2    Vil, M.D.3    Zhang, H.4    Jimenez, X.5    Bohlen, P.6    Witte, L.7    Zhu, Z.8
  • 72
    • 0032767275 scopus 로고    scopus 로고
    • ScFv multimers of the anti-neuraminidase antibody NC10: Length of the linker between VH and VL domains dictates precisely the transition between diabodies and triabodies
    • Atwell, J. L., Breheney, K. A., Lawrence, L. J., McCoy, A. J., Kortt, A. A., and Hudson, P. J. (1999) scFv multimers of the anti-neuraminidase antibody NC10: length of the linker between VH and VL domains dictates precisely the transition between diabodies and triabodies. Protein Eng. 12, 597-604
    • (1999) Protein Eng. , vol.12 , pp. 597-604
    • Atwell, J.L.1    Breheney, K.A.2    Lawrence, L.J.3    McCoy, A.J.4    Kortt, A.A.5    Hudson, P.J.6
  • 73
    • 3042587472 scopus 로고    scopus 로고
    • Involvement of the VEGF receptor 3 in tubular morphogenesis demonstrated with a human anti-human VEGFR-3 monoclonal antibody that antagonizes receptor activation by VEGF-C
    • Persaud, K., Tille, J. C., Liu, M., Zhu, Z., Jimenez, X., Pereira, D. S., Miao, H. Q., Brennan, L. A., Witte, L., Pepper, M. S., et al. (2004) Involvement of the VEGF receptor 3 in tubular morphogenesis demonstrated with a human anti-human VEGFR-3 monoclonal antibody that antagonizes receptor activation by VEGF-C. J. Cell Sci. 117, 2745-2756
    • (2004) J. Cell Sci. , vol.117 , pp. 2745-2756
    • Persaud, K.1    Tille, J.C.2    Liu, M.3    Zhu, Z.4    Jimenez, X.5    Pereira, D.S.6    Miao, H.Q.7    Brennan, L.A.8    Witte, L.9    Pepper, M.S.10
  • 74
    • 0034963191 scopus 로고    scopus 로고
    • Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105)
    • Nettelbeck, D. M., Miller, D. W., Jerome, V., Zuzarte, M., Watkins, S. J., Hawkins, R. E., Muller, R., and Kontermann, R. E. (2001) Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105). Mol. Ther. 3, 882-891
    • (2001) Mol. Ther. , vol.3 , pp. 882-891
    • Nettelbeck, D.M.1    Miller, D.W.2    Jerome, V.3    Zuzarte, M.4    Watkins, S.J.5    Hawkins, R.E.6    Muller, R.7    Kontermann, R.E.8
  • 75
    • 0034662636 scopus 로고    scopus 로고
    • Inhibition of tumor angiogenesis by a single-chain antibody directed against vascular endothelial growth factor
    • Vitaliti, A., Wittmer, M., Steiner, R., Wyder, L., Neri, D., and Klemenz, R. (2000) Inhibition of tumor angiogenesis by a single-chain antibody directed against vascular endothelial growth factor. Cancer Res. 60, 4311-4314
    • (2000) Cancer Res. , vol.60 , pp. 4311-4314
    • Vitaliti, A.1    Wittmer, M.2    Steiner, R.3    Wyder, L.4    Neri, D.5    Klemenz, R.6
  • 76
    • 0035328576 scopus 로고    scopus 로고
    • A strategy for antitumor vascular therapy by targeting the vascular endothelial growth factor: Receptor complex
    • Cooke, S. P., Boxer, G. M., Lawrence, L., Pedley, R. B., Spencer, D. I., Begent, R. H., and Chester, K. A. (2001) A strategy for antitumor vascular therapy by targeting the vascular endothelial growth factor: receptor complex. Cancer Res. 61, 3653-3659
    • (2001) Cancer Res. , vol.61 , pp. 3653-3659
    • Cooke, S.P.1    Boxer, G.M.2    Lawrence, L.3    Pedley, R.B.4    Spencer, D.I.5    Begent, R.H.6    Chester, K.A.7
  • 77
    • 0141788204 scopus 로고    scopus 로고
    • Single chain Fv antibody against angiopoietin-2 inhibits VEGF-induced endothelial cell proliferation and migration in vitro
    • Cai, M., Zhang, H., and Hui, R. (2003) Single chain Fv antibody against angiopoietin-2 inhibits VEGF-induced endothelial cell proliferation and migration in vitro. Biochem. Biophys. Res. Commun. 309, 946-951
    • (2003) Biochem. Biophys. Res. Commun. , vol.309 , pp. 946-951
    • Cai, M.1    Zhang, H.2    Hui, R.3
  • 78
    • 0035407983 scopus 로고    scopus 로고
    • Species-crossreactive scFv against the tumor stroma marker "fibroblast activation protein" selected by phage display from an immunized FAP-/- Knock-out mouse
    • Brocks, B., Garin-Chesa, P., Behrle, E., Park, J. E., Rettig, W. J., Pfizenmaier, K., and Moosmayer, D. (2001) Species-crossreactive scFv against the tumor stroma marker "fibroblast activation protein" selected by phage display from an immunized FAP-/- knock-out mouse. Mol. Med. 7, 461-469
    • (2001) Mol. Med. , vol.7 , pp. 461-469
    • Brocks, B.1    Garin-Chesa, P.2    Behrle, E.3    Park, J.E.4    Rettig, W.J.5    Pfizenmaier, K.6    Moosmayer, D.7
  • 79
    • 0034254216 scopus 로고    scopus 로고
    • Fusion of the tissue factor extracellular domain to a tumour stroma specific single-chain fragment variable antibody results in an antigen-specific coagulation-promoting molecule
    • Rippmann, J. F., Pfizenmaier, K., Mattes, R., Rettig, W. J., and Moosmayer, D. (2000) Fusion of the tissue factor extracellular domain to a tumour stroma specific single-chain fragment variable antibody results in an antigen-specific coagulation-promoting molecule. Biochem. J. 349, 805-812
    • (2000) Biochem. J. , vol.349 , pp. 805-812
    • Rippmann, J.F.1    Pfizenmaier, K.2    Mattes, R.3    Rettig, W.J.4    Moosmayer, D.5
  • 81
    • 0033555628 scopus 로고    scopus 로고
    • Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis
    • Viti, F., Tarli, L., Giovannoni, L., Zardi, L., and Neri, D. (1999) Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis. Cancer Res. 59, 347-352
    • (1999) Cancer Res. , vol.59 , pp. 347-352
    • Viti, F.1    Tarli, L.2    Giovannoni, L.3    Zardi, L.4    Neri, D.5
  • 82
    • 0036053161 scopus 로고    scopus 로고
    • Single-chain antibody-based gene therapy: Inhibition of tumor growth by in situ production of phage-derived human antibody fragments blocking functionally active sites of cell-associated matrices
    • Sanz, L., Kristensen, P., Blanco, B., Facteau, S., Russell, S. J., Winter, G., and Alvarez-Vallina, L. (2002) Single-chain antibody-based gene therapy: inhibition of tumor growth by in situ production of phage-derived human antibody fragments blocking functionally active sites of cell-associated matrices. Gene Ther. 9, 1049-1053
    • (2002) Gene Ther. , vol.9 , pp. 1049-1053
    • Sanz, L.1    Kristensen, P.2    Blanco, B.3    Facteau, S.4    Russell, S.J.5    Winter, G.6    Alvarez-Vallina, L.7
  • 83
    • 0033512542 scopus 로고    scopus 로고
    • Model systems to study the parameters determining the success of phage antibody selections on complex antigens
    • Mutuberria, R., Hoogenboom, H. R., van der, L. E., De Bruine, A. P., and Roovers, R. C. (1999) Model systems to study the parameters determining the success of phage antibody selections on complex antigens. J. Immunol. Methods 231, 65-81
    • (1999) J. Immunol. Methods , vol.231 , pp. 65-81
    • Mutuberria, R.1    Hoogenboom, H.R.2    Van Der, L.E.3    De Bruine, A.P.4    Roovers, R.C.5
  • 85
    • 0037133279 scopus 로고    scopus 로고
    • Molecular specialization of breast vasculature: A breast-homing phage-displayed peptide binds to aminopeptidase P in breast vasculature
    • Essler, M., and Ruoslahti, E. (2002) Molecular specialization of breast vasculature: a breast-homing phage-displayed peptide binds to aminopeptidase P in breast vasculature. Proc. Natl. Acad. Sci. USA 99, 2252-2257
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 2252-2257
    • Essler, M.1    Ruoslahti, E.2
  • 86
    • 1342330882 scopus 로고    scopus 로고
    • Perfusion of 99Tcm-labeled CD105 Mab into kidneys from patients with renal carcinoma suggests that CD105 is a promising vascular target
    • Costello, B., Li, C., Duff, S., Butterworth, D., Khan, A., Perkins, M., Owens, S., Al Mowallad, A. F., O'Dwyer, S., and Kumar, S. (2004) Perfusion of 99Tcm-labeled CD105 Mab into kidneys from patients with renal carcinoma suggests that CD105 is a promising vascular target. Int. J. Cancer 109, 436-441
    • (2004) Int. J. Cancer , vol.109 , pp. 436-441
    • Costello, B.1    Li, C.2    Duff, S.3    Butterworth, D.4    Khan, A.5    Perkins, M.6    Owens, S.7    Al Mowallad, A.F.8    O'Dwyer, S.9    Kumar, S.10
  • 88
    • 1042275537 scopus 로고    scopus 로고
    • Inhibitors of gelatinase B/matrix metalloproteinase-9 activity comparison of a peptidomimetic and polyhistidine with single-chain derivatives of a neutralizing monoclonal antibody
    • Hu, J., Van den Steen, P. E., Houde, M., Ilenchuk, T. T., and Opdenakker, G. (2004) Inhibitors of gelatinase B/matrix metalloproteinase-9 activity comparison of a peptidomimetic and polyhistidine with single-chain derivatives of a neutralizing monoclonal antibody. Biochem. Pharmacol. 67, 1001-1009
    • (2004) Biochem. Pharmacol. , vol.67 , pp. 1001-1009
    • Hu, J.1    Van Den Steen, P.E.2    Houde, M.3    Ilenchuk, T.T.4    Opdenakker, G.5
  • 89
    • 0036985699 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: Therapeutic implications
    • Ferrara, N. (2002) Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications. Semin. Oncol. 29, 10-14
    • (2002) Semin. Oncol. , vol.29 , pp. 10-14
    • Ferrara, N.1
  • 91
    • 0033870756 scopus 로고    scopus 로고
    • Targeted antiangiogenic therapy for cancer using Vitaxin: A humanized monoclonal antibody to the integrin alphavbeta3
    • Gutheil, J. C., Campbell, T. N., Pierce, P. R., Watkins, J. D., Huse, W. D., Bodkin, D. J., and Cheresh, D. A. (2000) Targeted antiangiogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin alphavbeta3. Clin. Cancer Res. 6, 3056-3061
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3056-3061
    • Gutheil, J.C.1    Campbell, T.N.2    Pierce, P.R.3    Watkins, J.D.4    Huse, W.D.5    Bodkin, D.J.6    Cheresh, D.A.7
  • 92
    • 0036839554 scopus 로고    scopus 로고
    • Integrin alpha V beta 3 as a target for treatment of rheumatoid arthritis and related rheumatic diseases
    • Wilder, R. L. (2002) Integrin alpha V beta 3 as a target for treatment of rheumatoid arthritis and related rheumatic diseases. Ann. Rheum. Dis. 61, Suppl 2, ii96-ii99
    • (2002) Ann. Rheum. Dis. , vol.61 , Issue.2 SUPPL.
    • Wilder, R.L.1
  • 93
    • 0037054942 scopus 로고    scopus 로고
    • Strategies for vascular targeting in tumors
    • Brekken, R. A., Li, C., and Kumar, S. (2002) Strategies for vascular targeting in tumors. Int. J. Cancer 100, 123-130
    • (2002) Int. J. Cancer , vol.100 , pp. 123-130
    • Brekken, R.A.1    Li, C.2    Kumar, S.3
  • 95
    • 1442286971 scopus 로고    scopus 로고
    • Bispecific single-chain diabody-mediated killing of endoglin-positive endothelial cells by cytotoxic T lymphocytes
    • Korn, T., Muller, R., and Kontermann, R. E. (2004) Bispecific single-chain diabody-mediated killing of endoglin-positive endothelial cells by cytotoxic T lymphocytes. J. Immunother. 27, 99-106
    • (2004) J. Immunother. , vol.27 , pp. 99-106
    • Korn, T.1    Muller, R.2    Kontermann, R.E.3
  • 96
    • 18744427000 scopus 로고    scopus 로고
    • Targeting of immunoliposomes to endothelial cells using a single-chain Fv fragment directed against human endoglin (CD105)
    • Volkel, T., Holig, P., Merdan, T., Muller, R., and Kontermann, R. E. (2004) Targeting of immunoliposomes to endothelial cells using a single-chain Fv fragment directed against human endoglin (CD105). Biochim. Biophys. Acta 1663, 158-166
    • (2004) Biochim. Biophys. Acta , vol.1663 , pp. 158-166
    • Volkel, T.1    Holig, P.2    Merdan, T.3    Muller, R.4    Kontermann, R.E.5
  • 97
    • 0035096320 scopus 로고    scopus 로고
    • Selective targeting of tumour neovasculature by a radiohalogenated human antibody fragment specific for the ED-B domain of fibronectin
    • Demartis, S., Tarli, L., Borsi, L., Zardi, L., and Neri, D. (2001) Selective targeting of tumour neovasculature by a radiohalogenated human antibody fragment specific for the ED-B domain of fibronectin. Eur. J. Nucleic Med. 28, 534-539
    • (2001) Eur. J. Nucleic Med. , vol.28 , pp. 534-539
    • Demartis, S.1    Tarli, L.2    Borsi, L.3    Zardi, L.4    Neri, D.5
  • 98
    • 0032827243 scopus 로고    scopus 로고
    • Selective targeting and photocoagulation of ocular angiogenesis mediated by a phage-derived human antibody fragment
    • Birchler, M., Viti, F., Zardi, L., Spiess, B., and Neri, D. (1999) Selective targeting and photocoagulation of ocular angiogenesis mediated by a phage-derived human antibody fragment. Nat. Biotechnol. 17, 984-988
    • (1999) Nat. Biotechnol. , vol.17 , pp. 984-988
    • Birchler, M.1    Viti, F.2    Zardi, L.3    Spiess, B.4    Neri, D.5
  • 99
    • 0036194917 scopus 로고    scopus 로고
    • Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature
    • Halin, C., Rondini, S., Nilsson, F., Berndt, A., Kosmehl, H., Zardi, L., and Neri, D. (2002) Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature. Nat. Biotechnol. 20, 264-269
    • (2002) Nat. Biotechnol. , vol.20 , pp. 264-269
    • Halin, C.1    Rondini, S.2    Nilsson, F.3    Berndt, A.4    Kosmehl, H.5    Zardi, L.6    Neri, D.7
  • 100
    • 0036493867 scopus 로고    scopus 로고
    • Enhancement of the antitumor properties of interleukin-2 by its targeted delivery to the tumor blood vessel extracellular matrix
    • Carnemolla, B., Borsi, L., Balza, E., Castellani, P., Meazza, R., Berndt, A., Ferrini, S., Kosmehl, H., Neri, D., and Zardi, L. (2002) Enhancement of the antitumor properties of interleukin-2 by its targeted delivery to the tumor blood vessel extracellular matrix. Blood 99, 1659-1665
    • (2002) Blood , vol.99 , pp. 1659-1665
    • Carnemolla, B.1    Borsi, L.2    Balza, E.3    Castellani, P.4    Meazza, R.5    Berndt, A.6    Ferrini, S.7    Kosmehl, H.8    Neri, D.9    Zardi, L.10
  • 101
    • 0035863566 scopus 로고    scopus 로고
    • Targeted delivery of tissue factor to the ED-B domain of fibronectin, a marker of angiogenesis, mediates the infarction of solid tumors in mice
    • Nilsson, F., Kosmehl, H., Zardi, L., and Neri, D. (2001) Targeted delivery of tissue factor to the ED-B domain of fibronectin, a marker of angiogenesis, mediates the infarction of solid tumors in mice. Cancer Res. 61, 711-716
    • (2001) Cancer Res. , vol.61 , pp. 711-716
    • Nilsson, F.1    Kosmehl, H.2    Zardi, L.3    Neri, D.4
  • 102
    • 0036649819 scopus 로고    scopus 로고
    • Cytotoxic targeting of F9 teratocarcinoma tumours with anti-ED-B fibronectin scFv antibody modified liposomes
    • Marty, C., Odermatt, B., Schott, H., Neri, D., Ballmer-Hofer, K., Klemenz, R., and Schwendener, R. A. (2002) Cytotoxic targeting of F9 teratocarcinoma tumours with anti-ED-B fibronectin scFv antibody modified liposomes. Br. J. Cancer 87, 106-112
    • (2002) Br. J. Cancer , vol.87 , pp. 106-112
    • Marty, C.1    Odermatt, B.2    Schott, H.3    Neri, D.4    Ballmer-Hofer, K.5    Klemenz, R.6    Schwendener, R.A.7
  • 104
    • 0035909785 scopus 로고    scopus 로고
    • Construction of a bispecific single chain antibody for recruitment of cytotoxic T cells to the tumour stroma associated antigen fibroblast activation protein
    • Wuest, T., Moosmayer, D., and Pfizenmaier, K. (2001) Construction of a bispecific single chain antibody for recruitment of cytotoxic T cells to the tumour stroma associated antigen fibroblast activation protein. J. Biotechnol. 92, 159-168
    • (2001) J. Biotechnol. , vol.92 , pp. 159-168
    • Wuest, T.1    Moosmayer, D.2    Pfizenmaier, K.3
  • 105
  • 106
    • 0036366705 scopus 로고    scopus 로고
    • Overview of antibody phage-display technology and its applications
    • Hoogenboom, H. R. (2002) Overview of antibody phage-display technology and its applications. Methods Mol. Biol. 178, 1-37
    • (2002) Methods Mol. Biol. , vol.178 , pp. 1-37
    • Hoogenboom, H.R.1
  • 107
    • 0036753710 scopus 로고    scopus 로고
    • Phage display technology: Clinical applications and recent innovations
    • Azzazy, H. M., and Highsmith, W. E., Jr. (2002) Phage display technology: clinical applications and recent innovations. Clin. Biochem. 35, 425-445
    • (2002) Clin. Biochem. , vol.35 , pp. 425-445
    • Azzazy, H.M.1    Highsmith Jr., W.E.2


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