scFv multimers of the anti-neuraminidase antibody NC10: Length of the linker between V(H) and V(L) domains dictates precisely the transition between diabodies and triabodies

Protein Engineering

Volumn 12, Issue 7, 1999, Pages 597-604

  Atwell, John L ^a   Breheney, Kerry A ^a   Lawrence, Lynne J ^a   McCoy, Airlie J ^b   Kortt, Alexander A ^a   Hudson, Peter J ^a  

^a CSIRO   (Australia)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

Antibody; Diabody; Dimers; Shorter linkers; Single chain Fvs; Triabody; Trimers

Indexed keywords

ANTIBODY; DIMER; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN FRAGMENT; NEURAMINIDASE ANTIBODY; POLYMER; SIALIDASE; UNCLASSIFIED DRUG;

ANTIBODY COMBINING SITE; ANTIBODY STRUCTURE; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; DIMERIZATION; ELECTRON MICROSCOPY; GEL PERMEATION CHROMATOGRAPHY; MOLECULAR MODEL; PRIORITY JOURNAL;

EID: 0032767275     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/12.7.597     Document Type: Article

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