Alterations in mitogen-activated protein kinase kinase and extracellular regulated kinase signaling in theca cells contribute to excessive androgen production in polycystic ovary syndrome

Molecular Endocrinology

Volumn 19, Issue 2, 2005, Pages 379-390

  Nelson Degrave, Velen L ^a   Wickenheisser, Jessica K ^a   Hendricks, Karen L ^a   Asano, Tomoichiro ^b   Fujishiro, Midori ^b   Legro, Richard S ^a   Kimball, Scot R ^a   Strauss III, Jerome F ^c   McAllister, Jan M ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYTOCHROME P450 17; INSULIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PRASTERONE;

ANDROGEN SYNTHESIS; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFECTION; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; THECA CELL;

ADENOVIRIDAE; ANDROGENS; ANIMALS; BLOTTING, WESTERN; CELL LINE; CELLS, CULTURED; DEHYDROEPIANDROSTERONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FLAVONOIDS; GENES, DOMINANT; HUMANS; INSULIN; LAC OPERON; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MUTATION; OVARY; PHOSPHORYLATION; POLYCYSTIC OVARY SYNDROME; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; STEROID 17-ALPHA-HYDROXYLASE; STEROIDS; THECA CELLS; TIME FACTORS; TRANSFECTION;

FALLOPIA;

EID: 13544276291     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2004-0178     Document Type: Article

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