Down-regulation of steroidogenic response to gonadotropins in human and rat preovulatory granulosa cells involves mitogen-activated protein kinase activation and modulation of DAX-1 and steroidogenic factor-1

Journal of Clinical Endocrinology and Metabolism

Volumn 88, Issue 5, 2003, Pages 2288-2299

  Tajima, Kimihisa ^a   Dantes, Ada ^a   Yao, Zhong ^a   Sorokina, Ksenia ^c   Kotsuji, Fumikazu ^b   Seger, Rony ^a   Amsterdam, Abraham ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF FUKUI   (Japan)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYTOCHROME P450; DOSAGE SENSITIVE SEX REVERSAL ADRENAL HYPOPLASIA CONGENITAL CRITICAL REGION ON THE X CHROMOSOME GENE 1 TRANSCRIPTION FACTOR; FOLLITROPIN; FORSKOLIN; GONADOTROPIN; LUTEINIZING HORMONE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROGESTERONE; STEROIDOGENIC ACUTE REGULATORY PROTEIN; STEROIDOGENIC FACTOR 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; ATTENUATION; CELL CULTURE; CELL LEVEL; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; FERTILIZATION IN VITRO; GRANULOSA CELL; HORMONE ACTION; HORMONE RESPONSE; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; INCUBATION TIME; INTRACELLULAR SPACE; LUTEINIZATION; MITOCHONDRION; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STEROIDOGENESIS;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; CELL NUCLEUS; CELLS, CULTURED; CHORIONIC GONADOTROPIN; DNA-BINDING PROTEINS; ENZYME ACTIVATION; ENZYME INHIBITORS; FEMALE; FLAVONOIDS; FOLLICLE STIMULATING HORMONE; FORSKOLIN; FUSHI TARAZU TRANSCRIPTION FACTORS; GENE EXPRESSION; GONADOTROPINS; GRANULOSA CELLS; HOMEODOMAIN PROTEINS; HUMANS; LUTEINIZING HORMONE; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; OVULATION; PHOSPHOPROTEINS; PHOSPHORYLATION; RATS; RATS, WISTAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; REPRESSOR PROTEINS; STEROIDS; TRANSCRIPTION FACTORS;

EID: 0037692855     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2002-020913     Document Type: Article

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