γ-secretase inhibitors: Still in the running as Alzheimer's therapeutics

Drug Discovery Today: Therapeutic Strategies

Volumn 1, Issue 1, 2004, Pages 1-6

  Marjaux, Els ^a   De Strooper, Bart ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; ASPARTIC PROTEINASE; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR 4; FLURBIPROFEN; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; IMATINIB; ISOCOUMARIN DERIVATIVE; KENPAULLONE; LITHIUM CHLORIDE; LY 411575; MEMBRANE PROTEIN; N [N (3,5 DIFLUOROPHENACETYL)ALANYL] S PHENYLGLYCINE TERT BUTYL ESTER; NICASTRIN; NONSTEROID ANTIINFLAMMATORY AGENT; NOTCH RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHOTRANSFERASE INHIBITOR; PRESENILIN 1; PROSTAGLANDIN SYNTHASE; PROTEINASE; PROTEINASE INHIBITOR; RHO FACTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALZHEIMER DISEASE; ARTICLE; CLINICAL TRIAL; DRUG BINDING SITE; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; GASTROINTESTINAL TOXICITY; HUMAN; MENTAL DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

EID: 13444274739     PISSN: 17406773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddstr.2004.05.001     Document Type: Review

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