Zebrafish as a pharmacological tool: The how, why and when

Current Opinion in Pharmacology

Volumn 4, Issue 5, 2004, Pages 504-512

  Goldsmith, Paul ^a  

^a VASTox plc   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMITRIPTYLINE; ASTEMIZOLE; ATORVASTATIN; CARBACHOL; CHEMICAL COMPOUND; DIAZEPAM; EPINASTINE; ERYTHROMYCIN; ETIDRONIC ACID; FUMAGILLOL CHLOROACETYLCARBAMATE; INDOMETACIN; MESALAZINE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N(G) NITROARGININE METHYL ESTER; NITROPRUSSIDE SODIUM; POTASSIUM CHANNEL HERG; PREDNISOLONE; QUINIDINE; SOTALOL; TERFENADINE; VATALANIB; WARFARIN;

ABSORPTION; ANIMAL MODEL; ANIMAL TISSUE; DISEASE MODEL; DRUG IDENTIFICATION; EMBRYO; INVERTEBRATE; MEDICAL RESEARCH; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; QT INTERVAL; REVIEW; SEQUENCE HOMOLOGY; VERTEBRATE; ZEBRA FISH; ANIMAL; COMPARATIVE STUDY; DRUG SCREENING; GENETICS; MAMMAL; METHODOLOGY; PHYSIOLOGY; PRENATAL DEVELOPMENT; SPECIES DIFFERENCE;

ANIMALS; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; MAMMALS; SPECIES SPECIFICITY; ZEBRAFISH;

EID: 13444272394     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coph.2004.04.005     Document Type: Review

References (69)

1. D.J. Grunwald G. Streisinger Induction of recessive lethal and specific locus mutations in the zebrafish with ethyl nitrosourea Genet Res 59 1992 103-116
2. E.W. Knapik ENU mutagenesis in zebrafish - from genes to complex diseases Mamm Genome 11 2000 511-519
3. A. Amsterdam S. Burgess G. Golling W. Chen Z. Sun K. Townsend S. Farrington M. Haldi N. Hopkins A large-scale insertional mutagenesis screen in zebrafish Genes Dev 13 1999 2713-2724
4. R. Hampson S.M. Hughes Acridine mutagenesis of zebrafish (Danio rerio) Mutat Res 525 2003 1-9
5. A. Nasevicius S.C. Ekker Effective targeted gene 'knockdown' in zebrafish Nat Genet 26 2000 216-220
6. T. Schwerte D. Uberbacher B. Pelster Non-invasive imaging of blood cell concentration and blood distribution in zebrafish Danio rerio incubated in hypoxic conditions in vivo J Exp Biol 206 2003 1299-1307
7. J.Y. Sire F. Allizard O. Babiar J. Bourguignon A. Quilhac Scale development in zebrafish (Danio rerio) J Anat 190 1997 545-561
8. S.Y. Ho M. Pack S.A. Farber Analysis of small molecule metabolism in zebrafish Methods Enzymol 364 2003 408-426
9. S.K. Tong B.C. Chung Analysis of zebrafish cyp19 promoters J Steroid Biochem Mol Biol 86 2003 381-386
10. T. Sugahara C.C. Liu G. Carter T. Govind Pai M.C. Liu cDNA cloning, expression, and functional characterization of a zebrafish SULT1 cytosolic sulfotransferase Arch Biochem Biophys 414 2003 67-73
11. H. Teraoka W. Dong T. Hiraga Zebrafish as a novel experimental model for developmental toxicology Congenit Anom (Kyoto) 43 2003 123-132
12. Z. Lele P.H. Krone The zebrafish as a model system in developmental, toxicological and transgenic research Biotechnol Adv 14 1996 57-72
13. P. Mirkes M.E. McClure J.J. Heindel M. Sander Developmental toxicology in the 21st century: Multidisciplinary approaches using model organisms and genomics Birth Defects Res Part A Clin Mol Teratol 67 2003 21-34
14. J.M. Spitsbergen M.L. Kent The state of the art of the zebrafish model for toxicology and toxicologic pathology research-advantages and current limitations Toxicol Pathol 31 Suppl 2003 62-87
15. R.T. Peterson B.A. Link J.E. Dowling S.L. Schreiber Small molecule developmental screens reveal the logic and timing of vertebrate development Proc Natl Acad Sci USA 97 2000 12965-12969
16. M.S. Clark Y.J. Edwards D. Peterson S.W. Clifton A.J. Thompson M. Sasaki Y. Suzuki K. Kikuchi S. Watabe K. Kawakami Fugu et al. ESTs: New resources for transcription analysis and genome annotation Genome Res 13 2003 2747-2753
17. J.F. Caceres A.R. Kornblihtt Alternative splicing: Multiple control mechanisms and involvement in human disease Trends Genet 18 2002 186-193
18. R.V. Davuluri I. Grosse M.Q. Zhang Computational identification of promoters and first exons in the human genome Nat Genet 29 2001 412-417
19. U. Langheinrich G. Vacun T. Wagner Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia Toxicol Appl Pharmacol 193 2003 370-382
20. K.C. Cheng R. Levenson J.D. Robishaw Functional genomic dissection of multimeric protein families in zebrafish Dev Dyn 228 2003 555-567
21. G. Jansen D. Weinkove R.H. Plasterk The G-protein gamma subunit gpc-1 of the nematode C. elegans is involved in taste adaptation EMBO J 21 2002 986-994
22. J.C. Venter M.D. Adams E.W. Myers P.W. Li R.J. Mural G.G. Sutton H.O. Smith M. Yandell C.A. Evans R.A. Holt et al. The sequence of the human genome Science 291 2001 1304-1351
23. R. Fredriksson E.T. Larson Y.L. Yan J.H. Postlethwait D. Larhammar Novel neuropeptide Y Y2-like receptor subtype in zebrafish and frogs supports early vertebrate chromosome duplications J Mol Evol 58 2004 106-114
24. N. Sin L. Meng M.Q. Wang J.J. Wen W.G. Bornmann C.M. Crews The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2 Proc Natl Acad Sci USA 94 1997 6099-6103
25. J.R. Yeh C.M. Crews Chemical genetics: Adding to the developmental biology toolbox Dev Cell 5 2003 11-19
26. R.T. Peterson J.D. Mably J.N. Chen M.C. Fishman Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul Curr Biol 11 2001 1481-1491
27. S.M. Khersonsky D.W. Jung T.W. Kang D.P. Walsh H.S. Moon H. Jo E.M. Jacobson V. Shetty T.A. Neubert Y.T. Chang Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening J Am Chem Soc 125 2003 11804-11805
28. M.R. Taylor J.B. Hurley H.A. Van Epps S.E. Brockerhoff A zebrafish model for pyruvate dehydrogenase deficiency: Rescue of neurological dysfunction and embryonic lethality using a ketogenic diet Proc Natl Acad Sci USA 101 2004 4584-4589
29. J.F. Rawls B.S. Samuel J.I. Gordon Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota Proc Natl Acad Sci USA 101 2004 4596-4601
30. J.T. Shin M.C. Fishman From zebrafish to human: Modular medical models Annu Rev Genomics Hum Genet 3 2002 311-340
31. K. Dooley L.I. Zon Zebrafish: A model system for the study of human disease Curr Opin Genet Dev 10 2000 252-256
32. T. Piotrowski D.G. Ahn T.F. Schilling S. Nair I. Ruvinsky R. Geisler G.J. Rauch P. Haffter L.I. Zon Y. Zhou et al. The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans Development 130 2003 5043-5052
33. P. Goldsmith W.A. Harris The zebrafish as a tool for understanding the biology of visual disorders Semin Cell Dev Biol 14 2003 11-18
34. R. Adler C. Curcio D. Hicks D. Price F. Wong Cell death in age-related macular degeneration Mol Vis 5 1999 31
35. P. Goldsmith H. Baier W.A. Harris Two zebrafish mutants, ebony and ivory, uncover benefits of neighborhood on photoreceptor survival J Neurobiol 57 2003 235-245
36. I.V. Zhdanova S.Y. Wang O.U. Leclair N.P. Danilova Melatonin promotes sleep-like state in zebrafish Brain Res 903 2001 263-268
37. R.J. Greenspan G. Tononi C. Cirelli P.J. Shaw Sleep and the fruit fly Trends Neurosci 24 2001 142-145
38. J. Kaslin J.M. Nystedt M. Ostergard N. Peitsaro P. Panula The orexin/ hypocretin system in zebrafish is connected to the aminergic and cholinergic systems J Neurosci 24 2004 2678-2689
39. F. Delaunay C. Thisse B. Thisse V. Laudet Differential regulation of Period 2 and Period 3 expression during development of the zebrafish circadian clock Gene Expr Patterns 3 2003 319-324
40. R. Gerlai Zebra fish: An uncharted behavior genetic model Behav Genet 33 2003 461-468
41. R. Gerlai M. Lahav S. Guo A. Rosenthal Drinks like a fish: Zebra fish (Danio rerio) as a behavior genetic model to study alcohol effects Pharmacol Biochem Behav 67 2000 773-782
42. K.R. Svoboda S. Vijayaraghavan R.L. Tanguay Nicotinic receptors mediate changes in spinal motoneuron development and axonal pathfinding in embryonic zebrafish exposed to nicotine J Neurosci 22 2002 10731-10741
43. V. Gonzalez-Nunez R. Gonzalez-Sarmiento R.E. Rodriguez Identification of two proopiomelanocortin genes in zebrafish (Danio rerio) Brain Res Mol Brain Res 120 2003 1-8
44. D.J. Milan T.A. Peterson J.N. Ruskin R.T. Peterson C.A. MacRae Drugs that induce repolarization abnormalities cause bradycardia in zebrafish Circulation 107 2003 1355-1358
45. G.A. Gintant J.T. Limberis J.S. McDermott C.D. Wegner B.F. Cox The canine Purkinje fiber: An in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis J Cardiovasc Pharmacol 37 2001 607-618
46. K. Yamamoto T. Tamura R. Imai M. Yamamoto Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole Toxicol Sci 60 2001 165-176
47. J. Chen A. Zou I. Splawski M.T. Keating M.C. Sanguinetti Long QT syndrome-associated mutations in the Per-Arnt-Sim (PAS) domain of HERG potassium channels accelerate channel deactivation J Biol Chem 274 1999 10113-10118
48. J.F. Amatruda J.L. Shepard H.M. Stern L.I. Zon Zebrafish as a cancer model system Cancer Cell 1 2002 229-231
49. D.M. Langenau D. Traver A.A. Ferrando J.L. Kutok J.C. Aster J.P. Kanki S. Lin E. Prochownik N.S. Trede L.I. Zon et al. Myc-induced T cell leukemia in transgenic zebrafish Science 299 2003 887-890
50. D. Sapede [Zebrafish, a model for migration of cancer cells?]. Med Sci (Paris) 19 2003 780-782
51. U. Langheinrich E. Hennen G. Stott G. Vacun Zebrafish as a model organism for the identification and characterization of drugs and genes affecting p53 signaling Curr Biol 12 2002 2023-2028
52. T.X. Liu N.G. Howlett M. Deng D.M. Langenau K. Hsu J. Rhodes J.P. Kanki A.D. D'Andrea A.T. Look Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis Dev Cell 5 2003 903-914
53. E. Chen S. Hermanson S.C. Ekker Syndecan-2 is essential for angiogenic sprouting during zebrafish development Blood 103 2004 1710-1719
54. J. Chan P.E. Bayliss J.M. Wood T.M. Roberts Dissection of angiogenic signaling in zebrafish using a chemical genetic approach Cancer Cell 1 2002 257-267
55. H.M. Stern L.I. Zon Cancer genetics and drug discovery in the zebrafish Nat Rev Cancer 3 2003 533-539
56. G.S. Tsao-Wu C.H. Weber L.R. Budgeon K.C. Cheng Agarose-embedded tissue arrays for histologic and genetic analysis Biotechniques 25 1998 614-618
57. M.A. Mohideen L.G. Beckwith G.S. Tsao-Wu J.L. Moore A.C. Wong M.R. Chinoy K.C. Cheng Histology-based screen for zebrafish mutants with abnormal cell differentiation Dev Dyn 228 2003 414-423
58. T. Kudoh M. Tsang N.A. Hukriede X. Chen M. Dedekian C.J. Clarke A. Kiang S. Schultz J.A. Epstein R. Toyama et al. A gene expression screen in zebrafish embryogenesis Genome Res 11 2001 1979-1987
59. H.G. Tomasiewicz D.B. Flaherty J.P. Soria J.G. Wood Transgenic zebrafish model of neurodegeneration J Neurosci Res 70 2002 734-745
60. A.C. Oates A.E. Bruce R.K. Ho Too much interference: Injection of double-stranded RNA has nonspecific effects in the zebrafish embryo Dev Biol 224 2000 20-28
61. Y.L. Yan C.T. Miller R.M. Nissen A. Singer D. Liu A. Kirn B. Draper J. Willoughby P.A. Morcos A. Amsterdam et al. A zebrafish sox9 gene required for cartilage morphogenesis Development 129 2002 5065-5079
62. M.L. McWhorter U.R. Monani A.H. Burghes C.E. Beattie Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding J Cell Biol 162 2003 919-931
63. J.R. Guyon A.N. Mosley Y. Zhou K.F. O'Brien X. Sheng K. Chiang A.J. Davidson J.M. Volinski L.I. Zon L.M. Kunkel The dystrophin associated protein complex in zebrafish Hum Mol Genet 12 2003 601-615
64. K.Y. Lee H. Huang B. Ju Z. Yang S. Lin Cloned zebrafish by nuclear transfer from long-term-cultured cells Nat Biotechnol 20 2002 795-799
65. K. Kurita S.M. Burgess N. Sakai Transgenic zebrafish produced by retroviral infection of in vitro-cultured sperm Proc Natl Acad Sci USA 101 2004 1263-1267
66. E. Wienholds F. van Eeden M. Kosters J. Mudde R.H. Plasterk E. Cuppen Efficient target-selected mutagenesis in zebrafish Genome Res 13 2003 2700-2707
67. J. Lo S. Lee M. Xu F. Liu H. Ruan A. Eun Y. He W. Ma W. Wang Z. Wen et al. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis Genome Res 13 2003 455-466
68. P.R. Wheater H.G. Burkitt V.G. Daniels Functional Histology: Text & Colour Atlas 1987 Churchill Livingstone Edinburgh
69. R.T. Peterson S.Y. Shaw T.A. Peterson D.J. Milan T.P. Zhong S.L. Schreiber C.A. MacRae M.C. Fishman Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation Nat Biotechnol 22 2004 595-599