The canine Purkinje fiber: An in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis

Journal of Cardiovascular Pharmacology

Volumn 37, Issue 5, 2001, Pages 607-618

  Gintant, Gary A ^a   Limberis, James T ^a   McDermott, Jeff S ^a   Wegner, Craig D ^a   Cox, Bryan F ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Acquired long QT interval; Action potential duration; Canine Purkinje fibers; iKr; Repolarization arrhythmias; Torsade de pointes

Indexed keywords

AZITHROMYCIN; CISAPRIDE; ENALAPRIL; ERYTHROMYCIN; FLUOXETINE; GREPAFLOXACIN; INDOMETACIN; MOXIFLOXACIN; PINACIDIL; SERTINDOLE; SOTALOL; TERFENADINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARRHYTHMOGENESIS; ARTICLE; CONTROLLED STUDY; DOG; DOSE RESPONSE; DRUG EFFECT; FEMALE; HEART REPOLARIZATION; IN VITRO STUDY; MALE; MUSCLE FIBER MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PURKINJE FIBER; QT INTERVAL; SWINE; TORSADE DES POINTES;

ACTION POTENTIALS; ANIMALS; ANTI-INFECTIVE AGENTS; ARRHYTHMIA; AZA COMPOUNDS; CISAPRIDE; DOGS; ERYTHROMYCIN; FEMALE; FLUOROQUINOLONES; IMIDAZOLES; INDOLES; LONG QT SYNDROME; MALE; MODELS, BIOLOGICAL; PERFUSION; PIPERAZINES; PURKINJE FIBERS; QUINOLINES; SOTALOL; SWINE; TORSADES DE POINTES;

EID: 0035038217     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200105000-00012     Document Type: Article

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