-
1
-
-
0031260579
-
Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas
-
Apelqvist A. Ahlgren U. Edlund H. Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas Curr. Biol. 7 1997 801-804
-
(1997)
Curr. Biol.
, vol.7
, pp. 801-804
-
-
Apelqvist, A.1
Ahlgren, U.2
Edlund, H.3
-
2
-
-
0036903270
-
Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation
-
Aubert J. Dunstan H. Chambers I. Smith A. Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation Nat. Biotechnol. 20 2002 1240-1245
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 1240-1245
-
-
Aubert, J.1
Dunstan, H.2
Chambers, I.3
Smith, A.4
-
3
-
-
0036527350
-
Dissection of angiogenic signaling in zebrafish using a chemical genetic approach
-
Chan J. Bayliss P.E. Wood J.M. Roberts T.M. Dissection of angiogenic signaling in zebrafish using a chemical genetic approach Cancer Cell 1 2002 257-267
-
(2002)
Cancer Cell
, vol.1
, pp. 257-267
-
-
Chan, J.1
Bayliss, P.E.2
Wood, J.M.3
Roberts, T.M.4
-
6
-
-
0032486433
-
Teratogen-mediated inhibition of target tissue response to Shh signaling
-
Cooper M.K. Porter J.A. Young K.E. Beachy P.A. Teratogen-mediated inhibition of target tissue response to Shh signaling Science 280 1998 1603-1607
-
(1998)
Science
, vol.280
, pp. 1603-1607
-
-
Cooper, M.K.1
Porter, J.A.2
Young, K.E.3
Beachy, P.A.4
-
7
-
-
0033178766
-
Chemical genetics: Exploring and controlling cellular processes with chemical probes
-
Crews C.M. Splittgerber U. Chemical genetics: exploring and controlling cellular processes with chemical probes Trends Biochem. Sci. 24 1999 317-320
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 317-320
-
-
Crews, C.M.1
Splittgerber, U.2
-
8
-
-
0037181078
-
A combinatorial scaffold approach toward kinase-directed heterocycle libraries
-
Ding S. Gray N.S. Wu X. Ding Q. Schultz P.G. A combinatorial scaffold approach toward kinase-directed heterocycle libraries J. Am. Chem. Soc. 124 2002 1594-1596
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 1594-1596
-
-
Ding, S.1
Gray, N.S.2
Wu, X.3
Ding, Q.4
Schultz, P.G.5
-
11
-
-
0034945354
-
Hindbrain patterning involves graded responses to retinoic acid signalling
-
Dupe V. Lumsden A. Hindbrain patterning involves graded responses to retinoic acid signalling Development 128 2001 2199-2208
-
(2001)
Development
, vol.128
, pp. 2199-2208
-
-
Dupe, V.1
Lumsden, A.2
-
12
-
-
18644368453
-
Small-molecule modulators of Hedgehog signaling: Identification and characterization of Smoothened agonists and antagonists
-
Frank-Kamenetsky M. Zhang X.M. Bottega S. Guicherit O. Wichterle H. Dudek H. Bumcrot D. Wang F.Y. Jones S. Shulok J. Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists J. Biol. 1 2002 10
-
(2002)
J. Biol.
, vol.1
, pp. 10
-
-
Frank-Kamenetsky, M.1
Zhang, X.M.2
Bottega, S.3
Guicherit, O.4
Wichterle, H.5
Dudek, H.6
Bumcrot, D.7
Wang, F.Y.8
Jones, S.9
Shulok, J.10
-
13
-
-
0032126768
-
Initiation of rhombomeric Hoxb4 expression requires induction by somites and a retinoid pathway
-
Gould A. Itasaki N. Krumlauf R. Initiation of rhombomeric Hoxb4 expression requires induction by somites and a retinoid pathway Neuron 21 1998 39-51
-
(1998)
Neuron
, vol.21
, pp. 39-51
-
-
Gould, A.1
Itasaki, N.2
Krumlauf, R.3
-
14
-
-
0031954428
-
Defined concentrations of a posteriorizing signal are critical for MafB/Kreisler segmental expression in the hindbrain
-
Grapin-Botton A. Bonnin M.A. Sieweke M. Le Douarin N.M. Defined concentrations of a posteriorizing signal are critical for MafB/Kreisler segmental expression in the hindbrain Development 125 1998 1173-1181
-
(1998)
Development
, vol.125
, pp. 1173-1181
-
-
Grapin-Botton, A.1
Bonnin, M.A.2
Sieweke, M.3
Le Douarin, N.M.4
-
15
-
-
0031171961
-
Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin
-
Griffith E.C. Zhuang S. Turk B.E. Chen S. Chang Y.-H. Wu Z. Biemann K. Liu J.O. Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin Chem. Biol. 4 1997 461-471
-
(1997)
Chem. Biol.
, vol.4
, pp. 461-471
-
-
Griffith, E.C.1
Zhuang, S.2
Turk, B.E.3
Chen, S.4
Chang, Y.-H.5
Wu, Z.6
Biemann, K.7
Liu, J.O.8
-
16
-
-
0035173514
-
Expression patterns of Fgf-8 during development and limb regeneration of the axolotl
-
Han M.J. An J.Y. Kim W.S. Expression patterns of Fgf-8 during development and limb regeneration of the axolotl Dev. Dyn. 220 2001 40-48
-
(2001)
Dev. Dyn.
, vol.220
, pp. 40-48
-
-
Han, M.J.1
An, J.Y.2
Kim, W.S.3
-
17
-
-
2642589990
-
Notochord repression of endodermal Sonic hedgehog permits pancreas development
-
Hebrok M. Kim S.K. Melton D.A. Notochord repression of endodermal Sonic hedgehog permits pancreas development Genes Dev. 12 1998 1705-1713
-
(1998)
Genes Dev.
, vol.12
, pp. 1705-1713
-
-
Hebrok, M.1
Kim, S.K.2
Melton, D.A.3
-
18
-
-
0035797907
-
Positional cloning of heart and soul reveals multiple roles for PKC lambda in zebrafish organogenesis
-
Horne-Badovinac S. Lin D. Waldron S. Schwarz M. Mbamalu G. Pawson T. Jan Y. Stainier D.Y. Abdelilah-Seyfried S. Positional cloning of heart and soul reveals multiple roles for PKC lambda in zebrafish organogenesis Curr. Biol. 11 2001 1492-1502
-
(2001)
Curr. Biol.
, vol.11
, pp. 1492-1502
-
-
Horne-Badovinac, S.1
Lin, D.2
Waldron, S.3
Schwarz, M.4
Mbamalu, G.5
Pawson, T.6
Jan, Y.7
Stainier, D.Y.8
Abdelilah-Seyfried, S.9
-
19
-
-
0018232837
-
Cyclopamine and related steroidal alkaloid teratogens: Their occurrence, structural relationship, and biologic effects
-
Keeler R.F. Cyclopamine and related steroidal alkaloid teratogens: their occurrence, structural relationship, and biologic effects Lipids 13 1978 708-715
-
(1978)
Lipids
, vol.13
, pp. 708-715
-
-
Keeler, R.F.1
-
20
-
-
0031214668
-
Transcriptional control: Calling in histone deacetylase
-
Kiermaier A. Eilers M. Transcriptional control: calling in histone deacetylase Curr. Biol. 7 1997 R505-R507
-
(1997)
Curr. Biol.
, vol.7
-
-
Kiermaier, A.1
Eilers, M.2
-
21
-
-
0032573227
-
Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor
-
Kim S.K. Melton D.A. Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor Proc. Natl. Acad. Sci. USA 95 1998 13036-13041
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13036-13041
-
-
Kim, S.K.1
Melton, D.A.2
-
22
-
-
0033485896
-
Chemistry or biology: Which comes first after the genome is sequenced?
-
King R.W. Chemistry or biology: which comes first after the genome is sequenced? Chem. Biol. 6 1999 R327-R333
-
(1999)
Chem. Biol.
, vol.6
-
-
King, R.W.1
-
23
-
-
0037079077
-
Chemical genetics: A small molecule approach to neurobiology
-
Koh B. Crews C.M. Chemical genetics: a small molecule approach to neurobiology Neuron 36 2002 563-566
-
(2002)
Neuron
, vol.36
, pp. 563-566
-
-
Koh, B.1
Crews, C.M.2
-
24
-
-
18844467411
-
T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities
-
Lee G. Elwood F. McNally J. Weiszmann J. Lindstrom M. Amaral K. Nakamura M. Miao S. Cao P. Learned R.M. et al. T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities J. Biol. Chem. 277 2002 19649-19657
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19649-19657
-
-
Lee, G.1
Elwood, F.2
McNally, J.3
Weiszmann, J.4
Lindstrom, M.5
Amaral, K.6
Nakamura, M.7
Miao, S.8
Cao, P.9
Learned, R.M.10
-
25
-
-
0036897351
-
Histone deacetylase activity is necessary for oligodendrocyte lineage progression
-
Marin-Husstege M. Muggironi M. Liu A. Casaccia-Bonnefil P. Histone deacetylase activity is necessary for oligodendrocyte lineage progression J. Neurosci. 22 2002 10333-10345
-
(2002)
J. Neurosci.
, vol.22
, pp. 10333-10345
-
-
Marin-Husstege, M.1
Muggironi, M.2
Liu, A.3
Casaccia-Bonnefil, P.4
-
27
-
-
0033387974
-
The development of the pattern of retinal ganglion cells in the chick retina: Mechanisms that control differentiation
-
McCabe K.L. Gunther E.C. Reh T.A. The development of the pattern of retinal ganglion cells in the chick retina: mechanisms that control differentiation Development 126 1999 5713-5724
-
(1999)
Development
, vol.126
, pp. 5713-5724
-
-
McCabe, K.L.1
Gunther, E.C.2
Reh, T.A.3
-
28
-
-
0037271081
-
Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila
-
Micchelli C.A. Esler W.P. Kimberly W.T. Jack C. Berezovska O. Kornilova A. Hyman B.T. Perrimon N. Wolfe M.S. Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila FASEB J. 17 2003 79-81
-
(2003)
FASEB J.
, vol.17
, pp. 79-81
-
-
Micchelli, C.A.1
Esler, W.P.2
Kimberly, W.T.3
Jack, C.4
Berezovska, O.5
Kornilova, A.6
Hyman, B.T.7
Perrimon, N.8
Wolfe, M.S.9
-
29
-
-
0034949207
-
Binary specification of nerve cord and notochord cell fates in ascidian embryos
-
Minokawa T. Yagi K. Makabe K.W. Nishida H. Binary specification of nerve cord and notochord cell fates in ascidian embryos Development 128 2001 2007-2017
-
(2001)
Development
, vol.128
, pp. 2007-2017
-
-
Minokawa, T.1
Yagi, K.2
Makabe, K.W.3
Nishida, H.4
-
32
-
-
0032841827
-
Zebrafish sparse corresponds to an orthologue of c-kit and is required for the morphogenesis of a subpopulation of melanocytes, but is not essential for hematopoiesis or primordial germ cell development
-
Parichy D.M. Rawls J.F. Pratt S.J. Whitfield T.T. Johnson S.L. Zebrafish sparse corresponds to an orthologue of c-kit and is required for the morphogenesis of a subpopulation of melanocytes, but is not essential for hematopoiesis or primordial germ cell development Development 126 1999 3425-3436
-
(1999)
Development
, vol.126
, pp. 3425-3436
-
-
Parichy, D.M.1
Rawls, J.F.2
Pratt, S.J.3
Whitfield, T.T.4
Johnson, S.L.5
-
33
-
-
0036233469
-
Inhibition and reversal of myogenic differentiation by purine-based microtubule assembly inhibitors
-
Perez O.D. Chang Y.T. Rosania G. Sutherlin D. Schultz P.G. Inhibition and reversal of myogenic differentiation by purine-based microtubule assembly inhibitors Chem. Biol. 9 2002 475-483
-
(2002)
Chem. Biol.
, vol.9
, pp. 475-483
-
-
Perez, O.D.1
Chang, Y.T.2
Rosania, G.3
Sutherlin, D.4
Schultz, P.G.5
-
34
-
-
0034700166
-
Small molecule developmental screens reveal the logic and timing of vertebrate development
-
Peterson R.T. Link B.A. Dowling J.E. Schreiber S.L. Small molecule developmental screens reveal the logic and timing of vertebrate development Proc. Natl. Acad. Sci. USA 97 2000 12965-12969
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12965-12969
-
-
Peterson, R.T.1
Link, B.A.2
Dowling, J.E.3
Schreiber, S.L.4
-
35
-
-
0035797939
-
Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul
-
Peterson R.T. Mably J.D. Chen J.N. Fishman M.C. Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul Curr. Biol. 11 2001 1481-1491
-
(2001)
Curr. Biol.
, vol.11
, pp. 1481-1491
-
-
Peterson, R.T.1
Mably, J.D.2
Chen, J.N.3
Fishman, M.C.4
-
37
-
-
0037337952
-
Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes
-
Rangappa S. Fen C. Lee E.H. Bongso A. Wei E.S. Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes Ann. Thorac. Surg. 75 2003 775-779
-
(2003)
Ann. Thorac. Surg.
, vol.75
, pp. 775-779
-
-
Rangappa, S.1
Fen, C.2
Lee, E.H.3
Bongso, A.4
Wei, E.S.5
-
38
-
-
0034016816
-
Myoseverin, a microtubule-binding molecule with novel cellular effects
-
Rosania G.R. Chang Y.T. Perez O. Sutherlin D. Dong H. Lockhart D.J. Schultz P.G. Myoseverin, a microtubule-binding molecule with novel cellular effects Nat. Biotechnol. 18 2000 304-308
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 304-308
-
-
Rosania, G.R.1
Chang, Y.T.2
Perez, O.3
Sutherlin, D.4
Dong, H.5
Lockhart, D.J.6
Schultz, P.G.7
-
39
-
-
0036628520
-
Cyclopamine induces digit loss in regenerating axolotl limbs
-
Roy S. Gardiner D.M. Cyclopamine induces digit loss in regenerating axolotl limbs J. Exp. Zool. 293 2002 186-190
-
(2002)
J. Exp. Zool.
, vol.293
, pp. 186-190
-
-
Roy, S.1
Gardiner, D.M.2
-
40
-
-
0031710509
-
Chemical genetics resulting from a passion for synthetic organic chemistry
-
Schreiber S.L. Chemical genetics resulting from a passion for synthetic organic chemistry Bioorg. Med. Chem. 6 1998 1127-1152
-
(1998)
Bioorg. Med. Chem.
, vol.6
, pp. 1127-1152
-
-
Schreiber, S.L.1
-
41
-
-
0035170549
-
Fgf signalling through MAPK cascade is required for development of the subpallial telencephalon in zebrafish embryos
-
Shinya M. Koshida S. Sawada A. Kuroiwa A. Takeda H. Fgf signalling through MAPK cascade is required for development of the subpallial telencephalon in zebrafish embryos Development 128 2001 4153-4164
-
(2001)
Development
, vol.128
, pp. 4153-4164
-
-
Shinya, M.1
Koshida, S.2
Sawada, A.3
Kuroiwa, A.4
Takeda, H.5
-
42
-
-
0030924753
-
The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2
-
Sin N. Meng L. Wang M.Q. Wen J.J. Bornmann W.G. Crews C.M. The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2 Proc. Natl. Acad. Sci. USA 94 1997 6099-6103
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6099-6103
-
-
Sin, N.1
Meng, L.2
Wang, M.Q.3
Wen, J.J.4
Bornmann, W.G.5
Crews, C.M.6
-
43
-
-
0036296171
-
Wnt-1 promotes neuronal differentiation and inhibits gliogenesis in P19 cells
-
Tang K. Yang J. Gao X. Wang C. Liu L. Kitani H. Atsumi T. Jing N. Wnt-1 promotes neuronal differentiation and inhibits gliogenesis in P19 cells Biochem. Biophys. Res. Commun. 293 2002 167-173
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.293
, pp. 167-173
-
-
Tang, K.1
Yang, J.2
Gao, X.3
Wang, C.4
Liu, L.5
Kitani, H.6
Atsumi, T.7
Jing, N.8
-
44
-
-
0033427808
-
Cell cycle arrest induced by ectopic expression of p27 is not sufficient to promote oligodendrocyte differentiation
-
Tang X.M. Beesley J.S. Grinspan J.B. Seth P. Kamholz J. Cambi F. Cell cycle arrest induced by ectopic expression of p27 is not sufficient to promote oligodendrocyte differentiation J. Cell. Biochem. 76 1999 270-279
-
(1999)
J. Cell. Biochem.
, vol.76
, pp. 270-279
-
-
Tang, X.M.1
Beesley, J.S.2
Grinspan, J.B.3
Seth, P.4
Kamholz, J.5
Cambi, F.6
-
47
-
-
0037065356
-
A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells
-
Wu X. Ding S. Ding Q. Gray N.S. Schultz P.G. A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells J. Am. Chem. Soc. 124 2002 14520-14521
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 14520-14521
-
-
Wu, X.1
Ding, S.2
Ding, Q.3
Gray, N.S.4
Schultz, P.G.5
-
48
-
-
0037144701
-
Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells
-
Xu C. Police S. Rao N. Carpenter M.K. Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells Circ. Res. 91 2002 501-508
-
(2002)
Circ. Res.
, vol.91
, pp. 501-508
-
-
Xu, C.1
Police, S.2
Rao, N.3
Carpenter, M.K.4
-
49
-
-
0029294663
-
Trichostatin A and trapoxin: Novel chemical probes for the role of histone acetylation in chromatin structure and function
-
Yoshida M. Horinouchi S. Beppu T. Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function Bioessays 17 1995 423-430
-
(1995)
Bioessays
, vol.17
, pp. 423-430
-
-
Yoshida, M.1
Horinouchi, S.2
Beppu, T.3
|