-
1
-
-
0029037649
-
Pathophysiology of insulin resistance in human disease
-
Reaven GM. Pathophysiology of insulin resistance in human disease. Physiol Rev 1995; 75: 473-86
-
(1995)
Physiol Rev
, vol.75
, pp. 473-486
-
-
Reaven, G.M.1
-
2
-
-
0035912744
-
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
-
Kim JK, Fillmore JJ, Chen Y, et al. Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc Natl Acad Sci U S A 2001; 98: 7522-7
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 7522-7527
-
-
Kim, J.K.1
Fillmore, J.J.2
Chen, Y.3
-
3
-
-
0037016727
-
Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructosefed hamster model of insulin resistance
-
Taghibiglou C, Rashid-Kolvear F, Van Iderstine SC, et al. Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructosefed hamster model of insulin resistance. J Biol Chem 2002; 277: 793-803
-
(2002)
J Biol Chem
, vol.277
, pp. 793-803
-
-
Taghibiglou, C.1
Rashid-Kolvear, F.2
Van Iderstine, S.C.3
-
4
-
-
0037047384
-
Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster
-
Carpentier A, Taghibiglou C, Leung N, et al. Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster. J Biol Chem 2002; 277: 28795-802
-
(2002)
J Biol Chem
, vol.277
, pp. 28795-28802
-
-
Carpentier, A.1
Taghibiglou, C.2
Leung, N.3
-
5
-
-
0035431018
-
Nonalcoholic fatty liver disease: A feature of the metabolic syndrome
-
Marchesini G, Brizi M, Blanchi G, et al. Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes 2001; 50: 1844-50
-
(2001)
Diabetes
, vol.50
, pp. 1844-1850
-
-
Marchesini, G.1
Brizi, M.2
Blanchi, G.3
-
6
-
-
0036312905
-
Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men
-
Seppala-Lindroos A, Vehkavaara S, Hakkinen AM, et al. Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. J Clin Endocrinol Metab 2002; 87: 3023-8
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 3023-3028
-
-
Seppala-Lindroos, A.1
Vehkavaara, S.2
Hakkinen, A.M.3
-
7
-
-
0036114844
-
Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
-
Petersen KF, Oral EA, Dufour S, et al. Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. J Clin Invest 2002; 109: 1345-50
-
(2002)
J Clin Invest
, vol.109
, pp. 1345-1350
-
-
Petersen, K.F.1
Oral, E.A.2
Dufour, S.3
-
8
-
-
0026040907
-
Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats
-
Kraegen EW, Clark PW, Jenkins AB, et al. Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats. Diabetes 1991; 40: 1397-403
-
(1991)
Diabetes
, vol.40
, pp. 1397-1403
-
-
Kraegen, E.W.1
Clark, P.W.2
Jenkins, A.B.3
-
9
-
-
0037324750
-
Insulin signaling is required for insulin's direct and indirect action on hepatic glucose production
-
Fisher SJ, Kahn CR. Insulin signaling is required for insulin's direct and indirect action on hepatic glucose production. J Clin Invest 2003; 111: 463-8
-
(2003)
J Clin Invest
, vol.111
, pp. 463-468
-
-
Fisher, S.J.1
Kahn, C.R.2
-
10
-
-
0034905540
-
Insulin stimulation of hepatic triacylglycerol secretion and the etiology of insulin resistance
-
Zammit VA, Waterman IJ, Topping D, et al. Insulin stimulation of hepatic triacylglycerol secretion and the etiology of insulin resistance. J Nutr 2001; 131: 2074-7
-
(2001)
J Nutr
, vol.131
, pp. 2074-2077
-
-
Zammit, V.A.1
Waterman, I.J.2
Topping, D.3
-
11
-
-
0033636523
-
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
-
Michael MD, Kulkarni RN, Postic C, et al. Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. Mol Cell 2000; 6: 87-97
-
(2000)
Mol Cell
, vol.6
, pp. 87-97
-
-
Michael, M.D.1
Kulkarni, R.N.2
Postic, C.3
-
12
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001; 414: 799-806
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
14
-
-
0034671645
-
Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo
-
Previs SF, Withers DJ, Ren JM, et al. Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo. J Biol Chem 2000; 275: 38990-4
-
(2000)
J Biol Chem
, vol.275
, pp. 38990-38994
-
-
Previs, S.F.1
Withers, D.J.2
Ren, J.M.3
-
16
-
-
0035002183
-
Insulin signalling
-
Bevan P. Insulin signalling. J Cell Sci 2001; 114: 1429-30
-
(2001)
J Cell Sci
, vol.114
, pp. 1429-1430
-
-
Bevan, P.1
-
18
-
-
0037908675
-
mNAT3, an N-system amino acid transporter expressed in hepatocytes and regulated by an insulin-activated and PI3 dinase-dependent signaling
-
Gu S, Langlais P, Liu F, et al. mNAT3, an N-system amino acid transporter expressed in hepatocytes and regulated by an insulin-activated and PI3 dinase-dependent signaling. Biochem J 2003; 371 (Pt 3): 721-31
-
(2003)
Biochem J
, vol.371
, Issue.PART 3
, pp. 721-731
-
-
Gu, S.1
Langlais, P.2
Liu, F.3
-
19
-
-
0021436667
-
Turnover and splanchnic metabolism of free fatty acids and ketones in insulin-dependent diabetics at rest and in response to exercise
-
Wahren J, Sato Y, Ostman J, et al. Turnover and splanchnic metabolism of free fatty acids and ketones in insulin-dependent diabetics at rest and in response to exercise. J Clin Invest 1984; 73: 1367-76
-
(1984)
J Clin Invest
, vol.73
, pp. 1367-1376
-
-
Wahren, J.1
Sato, Y.2
Ostman, J.3
-
21
-
-
0035084699
-
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
-
Sanyal AJ, Campbell-Sargent C, Mirshahi F, et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001; 120: 1183-92
-
(2001)
Gastroenterology
, vol.120
, pp. 1183-1192
-
-
Sanyal, A.J.1
Campbell-Sargent, C.2
Mirshahi, F.3
-
22
-
-
0344406146
-
Mechanisms of the free fatty acid-induced increase in hepatic glucose production
-
Lam TK, Carpentier A, Lewis GF, et al. Mechanisms of the free fatty acid-induced increase in hepatic glucose production. Am J Physiol Endocrinol Metab 2003; 284: E863-73
-
(2003)
Am J Physiol Endocrinol Metab
, vol.284
-
-
Lam, T.K.1
Carpentier, A.2
Lewis, G.F.3
-
23
-
-
0026627736
-
The lipolysis/esterification cycle of hepatic triacylglycerol: Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas
-
Wiggins D, Gibbons GF. The lipolysis/esterification cycle of hepatic triacylglycerol: its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas. Biochem J 1992; 284 (Pt 2): 457-62
-
(1992)
Biochem J
, vol.284
, Issue.PART 2
, pp. 457-462
-
-
Wiggins, D.1
Gibbons, G.F.2
-
24
-
-
0036330904
-
Plasma total and free fatty acids composition in human non-alcoholic steatohepatitis
-
de Almeida IT, Cortez-Pinto H, Fidalgo G, et al. Plasma total and free fatty acids composition in human non-alcoholic steatohepatitis. Clin Nutr 2002; 21: 219-23
-
(2002)
Clin Nutr
, vol.21
, pp. 219-223
-
-
De Almeida, I.T.1
Cortez-Pinto, H.2
Fidalgo, G.3
-
25
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI. Cellular mechanisms of insulin resistance. J Clin Invest 2000; 106: 171-6
-
(2000)
J Clin Invest
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
26
-
-
0033965557
-
Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice
-
Gavrilova O, Marcus-Samuels B, Graham D, et al. Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice. J Clin Invest 2000; 105: 271-8
-
(2000)
J Clin Invest
, vol.105
, pp. 271-278
-
-
Gavrilova, O.1
Marcus-Samuels, B.2
Graham, D.3
-
27
-
-
0026538763
-
Adipose tissue metabolism in obesity: Lipase action in vivo before and after a mixed meal
-
Coppack SW, Evans RD, Fisher RM, et al. Adipose tissue metabolism in obesity: lipase action in vivo before and after a mixed meal. Metabolism 1992; 41: 264-72
-
(1992)
Metabolism
, vol.41
, pp. 264-272
-
-
Coppack, S.W.1
Evans, R.D.2
Fisher, R.M.3
-
28
-
-
0033961009
-
Insulin regulation of plasma free fatty acid concentrations is abnormal in healthy subjects with muscle insulin resistance
-
Abbasi F, McLaughlin T, Lamendola C, et al. Insulin regulation of plasma free fatty acid concentrations is abnormal in healthy subjects with muscle insulin resistance. Metabolism 2000; 49: 151-4
-
(2000)
Metabolism
, vol.49
, pp. 151-154
-
-
Abbasi, F.1
McLaughlin, T.2
Lamendola, C.3
-
29
-
-
0034033372
-
Visceral fat and insulin resistance: Causative or correlative?
-
Frayn KN. Visceral fat and insulin resistance: causative or correlative? Br J Nutr 2000; 83 Suppl. 1: S71-7
-
(2000)
Br J Nutr
, vol.83
, Issue.SUPPL. 1
-
-
Frayn, K.N.1
-
30
-
-
0028091785
-
Regional adiposity and morbidity
-
Kissebah AH, Krakower GR. Regional adiposity and morbidity. Physiol Rev 1994; 74: 761-811
-
(1994)
Physiol Rev
, vol.74
, pp. 761-811
-
-
Kissebah, A.H.1
Krakower, G.R.2
-
31
-
-
0030809807
-
Intraabdominal adipose tissue and anthropometric surrogates in African American women with upper- and lower-body obesity
-
Conway JM, Chanetsa FF, Wang P. Intraabdominal adipose tissue and anthropometric surrogates in African American women with upper- and lower-body obesity. Am J Clin Nutr 1997; 66: 1345-51
-
(1997)
Am J Clin Nutr
, vol.66
, pp. 1345-1351
-
-
Conway, J.M.1
Chanetsa, F.F.2
Wang, P.3
-
32
-
-
0025151910
-
Metabolism of adipose tissue in intraabdominal depots in severely obese men and women
-
Rebuffe-Scrive M, Anderson B, Olbe L, et al. Metabolism of adipose tissue in intraabdominal depots in severely obese men and women. Metabolism 1990; 39: 1021-5
-
(1990)
Metabolism
, vol.39
, pp. 1021-1025
-
-
Rebuffe-Scrive, M.1
Anderson, B.2
Olbe, L.3
-
33
-
-
0038178062
-
Visceral fat and liver fat are independent predictors of metabolic risk factors in men
-
Nguyen-Duy TB, Nichaman MZ, Church TS, et al. Visceral fat and liver fat are independent predictors of metabolic risk factors in men. Am J Physiol Endocrinol Metab 2003; 284 (6): E1065-71
-
(2003)
Am J Physiol Endocrinol Metab
, vol.284
, Issue.6
-
-
Nguyen-Duy, T.B.1
Nichaman, M.Z.2
Church, T.S.3
-
34
-
-
0036310157
-
Extreme insulin resistance of the central adipose depot in vivo
-
Mittelman SD, Van Citters GW, Kirkman EL, et al. Extreme insulin resistance of the central adipose depot in vivo. Diabetes 2002; 51: 755-61
-
(2002)
Diabetes
, vol.51
, pp. 755-761
-
-
Mittelman, S.D.1
Van Citters, G.W.2
Kirkman, E.L.3
-
35
-
-
0032990467
-
Catecholamine-induced lipolysis in obesity
-
Arner P. Catecholamine-induced lipolysis in obesity. Int J Obes Relat Metab Disord 1999; 23 Suppl. 1: 10-3
-
(1999)
Int J Obes Relat Metab Disord
, vol.23
, Issue.SUPPL. 1
, pp. 10-13
-
-
Arner, P.1
-
36
-
-
0032999369
-
Free fatty acids impair hepatic insulin extraction in vivo
-
Wiesenthal SR, Sandhu H, McCall RH, et al. Free fatty acids impair hepatic insulin extraction in vivo. Diabetes 1999; 48: 766-74
-
(1999)
Diabetes
, vol.48
, pp. 766-774
-
-
Wiesenthal, S.R.1
Sandhu, H.2
McCall, R.H.3
-
37
-
-
0017286061
-
Mechanisms and regulation of biosynthesis of saturated fatty acids
-
Volpe JJ, Vagelos PR. Mechanisms and regulation of biosynthesis of saturated fatty acids. Physiol Rev 1976; 56: 339-417
-
(1976)
Physiol Rev
, vol.56
, pp. 339-417
-
-
Volpe, J.J.1
Vagelos, P.R.2
-
38
-
-
0029023184
-
Effects of acute exercise on hepatic lipogenic enzymes in fasted and refed rats
-
Griffiths MA, Baker DH, Yu XX, et al. Effects of acute exercise on hepatic lipogenic enzymes in fasted and refed rats. J Appl Physiol 1995; 79: 879-85
-
(1995)
J Appl Physiol
, vol.79
, pp. 879-885
-
-
Griffiths, M.A.1
Baker, D.H.2
Yu, X.X.3
-
39
-
-
0029964729
-
Contributions of de novo synthesis of fatty acids to total VLDL-triglyceride secretion during prolonged hyperglycemia/hyperinsulinemia in normal man
-
Aarsland A, Chinkes D, Wolfe RR. Contributions of de novo synthesis of fatty acids to total VLDL-triglyceride secretion during prolonged hyperglycemia/hyperinsulinemia in normal man. J Clin Invest 1996; 98: 2008-17
-
(1996)
J Clin Invest
, vol.98
, pp. 2008-2017
-
-
Aarsland, A.1
Chinkes, D.2
Wolfe, R.R.3
-
40
-
-
0033636780
-
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
-
Shimomura I, Matsuda M, Hammer RE, et al. Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. Mol Cell 2000; 6: 77-86
-
(2000)
Mol Cell
, vol.6
, pp. 77-86
-
-
Shimomura, I.1
Matsuda, M.2
Hammer, R.E.3
-
41
-
-
0037216466
-
Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, lowcarbohydrate and low-fat, high-carbohydrate isoenergetic diets
-
Schwarz JM, Linfoot P, Dare D, et al. Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, lowcarbohydrate and low-fat, high-carbohydrate isoenergetic diets. Am J Clin Nutr 2003; 77: 43-50
-
(2003)
Am J Clin Nutr
, vol.77
, pp. 43-50
-
-
Schwarz, J.M.1
Linfoot, P.2
Dare, D.3
-
42
-
-
0038517194
-
Concurrent exercise prevents highfat-diet-induced macrovesicular hepatic steatosis
-
Gauthier MS, Couturier K, Latour JG, et al. Concurrent exercise prevents highfat-diet-induced macrovesicular hepatic steatosis. J Appl Physiol 2003; 94: 2127-34
-
(2003)
J Appl Physiol
, vol.94
, pp. 2127-2134
-
-
Gauthier, M.S.1
Couturier, K.2
Latour, J.G.3
-
43
-
-
0024236326
-
Dependence of lipid-lipoprotein metabolism on exercise intensity in experimental fatty liver rats
-
Terao T, Fujise T, Yamashita Y, et al. Dependence of lipid-lipoprotein metabolism on exercise intensity in experimental fatty liver rats. Tokai J Exp Clin Med 1988; 13: 99-107
-
(1988)
Tokai J Exp Clin Med
, vol.13
, pp. 99-107
-
-
Terao, T.1
Fujise, T.2
Yamashita, Y.3
-
44
-
-
0029987520
-
Changes in insulin action, triglycerides, and lipid composition during sucrose feeding in rats
-
Pagliassotti MJ, Prach PA, Koppenhafer TA, et al. Changes in insulin action, triglycerides, and lipid composition during sucrose feeding in rats. Am J Physiol 1996; 271: R1319-26
-
(1996)
Am J Physiol
, vol.271
-
-
Pagliassotti, M.J.1
Prach, P.A.2
Koppenhafer, T.A.3
-
45
-
-
0036077035
-
Elevated basal PI 3-kinase activity and reduced insulin signaling in sucrose-induced hepatic insulin resistance
-
Pagliassotti MJ, Kang J, Thresher IS, et al. Elevated basal PI 3-kinase activity and reduced insulin signaling in sucrose-induced hepatic insulin resistance. Am J Physiol Endocrinol Metab 2002; 282: E170-6
-
(2002)
Am J Physiol Endocrinol Metab
, vol.282
-
-
Pagliassotti, M.J.1
Kang, J.2
Thresher, I.S.3
-
46
-
-
0031467268
-
Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia
-
Mittelman SD, Fu YY, Rebrin K, et al. Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia. J Clin Invest 1997; 100: 3121-30
-
(1997)
J Clin Invest
, vol.100
, pp. 3121-3130
-
-
Mittelman, S.D.1
Fu, Y.Y.2
Rebrin, K.3
-
47
-
-
0025297310
-
Peripheral effects of insulin dominate suppression of fasting hepatic glucose production
-
Ader M, Bergman RN. Peripheral effects of insulin dominate suppression of fasting hepatic glucose production. Am Physiol 1990; 258: E1020-32
-
(1990)
Am Physiol
, vol.258
-
-
Ader, M.1
Bergman, R.N.2
-
48
-
-
0030975131
-
Fatty acids mediate the acute extrahepatic effects of insulin on hepatic glucose production in humans
-
Lewis GF, Vranic M, Harley P, et al. Fatty acids mediate the acute extrahepatic effects of insulin on hepatic glucose production in humans. Diabetes 1997; 46: 1111-9
-
(1997)
Diabetes
, vol.46
, pp. 1111-1119
-
-
Lewis, G.F.1
Vranic, M.2
Harley, P.3
-
49
-
-
0036725464
-
Interaction between free fatty acids and glucose metabolism
-
Boden G. Interaction between free fatty acids and glucose metabolism. Curr Opin Clin Nutr Metab Care 2002; 5: 545-9
-
(2002)
Curr Opin Clin Nutr Metab Care
, vol.5
, pp. 545-549
-
-
Boden, G.1
-
50
-
-
0036092239
-
Banting lecture 2001: Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes
-
McGarry JD. Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 2002; 51: 7-18
-
(2002)
Diabetes
, vol.51
, pp. 7-18
-
-
McGarry, J.D.1
-
51
-
-
0031731373
-
Hyperglycemia-induced inhibition of splanchnic fatty acid oxidation increases hepatic triacylglycerol secretion
-
Sidossis LS, Mittendorfer B, Walser E, et al. Hyperglycemia-induced inhibition of splanchnic fatty acid oxidation increases hepatic triacylglycerol secretion. Am J Physiol 1998; 275: E798-805
-
(1998)
Am J Physiol
, vol.275
-
-
Sidossis, L.S.1
Mittendorfer, B.2
Walser, E.3
-
52
-
-
0029044495
-
Induction of fatty-acid-synthase gene expression by glucose in primary culture of rat hepatocytes: Dependency upon glucokinase activity
-
Prip-Buus C, Perdereau D, Foufelle F, et al. Induction of fatty-acid-synthase gene expression by glucose in primary culture of rat hepatocytes: dependency upon glucokinase activity. Eur J Biochem 1995; 230: 309-15
-
(1995)
Eur J Biochem
, vol.230
, pp. 309-315
-
-
Prip-Buus, C.1
Perdereau, D.2
Foufelle, F.3
-
53
-
-
0035123353
-
Glucokinase gene locus transgenic mice are resistant to the development of obesity-induced type 2 diabetes
-
Shiota M, Postic C, Fujimoto Y, et al. Glucokinase gene locus transgenic mice are resistant to the development of obesity-induced type 2 diabetes. Diabetes 2001; 50: 622-9
-
(2001)
Diabetes
, vol.50
, pp. 622-629
-
-
Shiota, M.1
Postic, C.2
Fujimoto, Y.3
-
54
-
-
0347477364
-
Long-term overexpression of glucokinase in the liver of transgenic mice leads to insulin resistance
-
Ferre T, Riu E, Franckhauser S, et al. Long-term overexpression of glucokinase in the liver of transgenic mice leads to insulin resistance. Diabetologia 2003; 46: 1662-8
-
(2003)
Diabetologia
, vol.46
, pp. 1662-1668
-
-
Ferre, T.1
Riu, E.2
Franckhauser, S.3
-
55
-
-
0037303077
-
Free fatty acids increase basal hepatic glucose production and induce hepatic insulin resistance at different sites
-
Lam TK, van de Werve G, Giacca A. Free fatty acids increase basal hepatic glucose production and induce hepatic insulin resistance at different sites. Am J Physiol Endocrinol Metab 2003; 284: E281-90
-
(2003)
Am J Physiol Endocrinol Metab
, vol.284
-
-
Lam, T.K.1
Van De Werve, G.2
Giacca, A.3
-
56
-
-
0020479806
-
Specific inhibition of glucokinase by long chain acyl coenzymes A below the critical micelle concentration
-
Tippett PS, Neet KE. Specific inhibition of glucokinase by long chain acyl coenzymes A below the critical micelle concentration. J Biol Chem 1982; 257: 12839-45
-
(1982)
J Biol Chem
, vol.257
, pp. 12839-12845
-
-
Tippett, P.S.1
Neet, K.E.2
-
57
-
-
0030152610
-
Disordered expression of glycolytic and gluconeogenic liver enzymes of juvenile visceral steatosis mice with systemic carnitine deficiency
-
Hotta K, Kuwajima M, Ono A, et al. Disordered expression of glycolytic and gluconeogenic liver enzymes of juvenile visceral steatosis mice with systemic carnitine deficiency. Diabetes Res Clin Pract 1996; 32: 117-23
-
(1996)
Diabetes Res Clin Pract
, vol.32
, pp. 117-123
-
-
Hotta, K.1
Kuwajima, M.2
Ono, A.3
-
58
-
-
0346671143
-
Glyceroneogenesis revisited
-
Hanson RW, Reshef L. Glyceroneogenesis revisited. Biochimie 2003; 85: 1199-205
-
(2003)
Biochimie
, vol.85
, pp. 1199-1205
-
-
Hanson, R.W.1
Reshef, L.2
-
59
-
-
0035918167
-
Glyceroneogenesis and the source of glycerol for hepatic triacylglycerol synthesis in humans
-
Kalhan SC, Mahajan S, Burkett E, et al. Glyceroneogenesis and the source of glycerol for hepatic triacylglycerol synthesis in humans. J Biol Chem 2001; 276: 12928-31
-
(2001)
J Biol Chem
, vol.276
, pp. 12928-12931
-
-
Kalhan, S.C.1
Mahajan, S.2
Burkett, E.3
-
60
-
-
0021959445
-
Hormonal regulation of fat esterification & oxidation in hepatocytes from fed rats: Modulation by 3-mercaptopicolinate
-
Schofield PS, Kirk CJ, Sugden MC. Hormonal regulation of fat esterification & oxidation in hepatocytes from fed rats: modulation by 3-mercaptopicolinate. Biochem Int 1985; 10: 695-704
-
(1985)
Biochem Int
, vol.10
, pp. 695-704
-
-
Schofield, P.S.1
Kirk, C.J.2
Sugden, M.C.3
-
61
-
-
0037189517
-
Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice
-
Sun Y, Liu S, Ferguson S, et al. Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice. J Biol Chem 2002; 277: 23301-7
-
(2002)
J Biol Chem
, vol.277
, pp. 23301-23307
-
-
Sun, Y.1
Liu, S.2
Ferguson, S.3
-
62
-
-
0026604851
-
Inhibition of glycolysis by 5-amino-4-imidazolecarboxamide riboside in isolated rat hepatocytes
-
Vincent MF, Bontemps F, Van den Berghe G. Inhibition of glycolysis by 5-amino-4-imidazolecarboxamide riboside in isolated rat hepatocytes. Biochem J 1992; 281 (Pt 1): 267-72
-
(1992)
Biochem J
, vol.281
, Issue.PART 1
, pp. 267-272
-
-
Vincent, M.F.1
Bontemps, F.2
Van Den Berghe, G.3
-
63
-
-
0031568242
-
Control of hepatic fatty acid oxidation by 5́-AMP-activated protein kinase involves a malonyl-CoA-dependent and a malonyl-CoA-independent mechanism
-
Velasco G, Geelen MJ, Guzman M. Control of hepatic fatty acid oxidation by 5́-AMP-activated protein kinase involves a malonyl-CoA-dependent and a malonyl-CoA-independent mechanism. Arch Biochem Biophys 1997; 337: 169-75
-
(1997)
Arch Biochem Biophys
, vol.337
, pp. 169-175
-
-
Velasco, G.1
Geelen, M.J.2
Guzman, M.3
-
64
-
-
0033559856
-
AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: Evidence that sn-glycerol-3-phosphate acyltransferase is a novel target
-
Muoio DM, Seefeld K, Witters LA, et al. AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target. Biochem J 1999; 338 (Pt 3): 783-91
-
(1999)
Biochem J
, vol.338
, Issue.PART 3
, pp. 783-791
-
-
Muoio, D.M.1
Seefeld, K.2
Witters, L.A.3
-
65
-
-
0032792665
-
AMP-activated protein kinase, a metabolic master switch: Possible roles in type 2 diabetes
-
Winder WW, Hardie DG. AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes. Am J Physiol 1999; 277: E1-10
-
(1999)
Am J Physiol
, vol.277
-
-
Winder, W.W.1
Hardie, D.G.2
-
66
-
-
0036788292
-
AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats
-
Iglesias MA, Ye JM, Frangioudakis G, et al. AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats. Diabetes 2002; 51: 2886-94
-
(2002)
Diabetes
, vol.51
, pp. 2886-2894
-
-
Iglesias, M.A.1
Ye, J.M.2
Frangioudakis, G.3
-
67
-
-
0036086955
-
Prior exercise and the response to insulin-induced hypoglycemia in the dog
-
Koyama Y, Galassetti P, Coker RH, et al. Prior exercise and the response to insulin-induced hypoglycemia in the dog. Am J Physiol Endocrinol Metab 2002; 282: E1128-38
-
(2002)
Am J Physiol Endocrinol Metab
, vol.282
-
-
Koyama, Y.1
Galassetti, P.2
Coker, R.H.3
-
68
-
-
0042767653
-
Interaction of insulin and prior exercise in control of hepatic metabolism of a glucose load
-
Pencek RR, James F, Lacy DB, et al. Interaction of insulin and prior exercise in control of hepatic metabolism of a glucose load. Diabetes 2003; 52: 1897-903
-
(2003)
Diabetes
, vol.52
, pp. 1897-1903
-
-
Pencek, R.R.1
James, F.2
Lacy, D.B.3
-
69
-
-
0023579696
-
Enhanced peripheral and splanchnic insulin sensitivity in NIDDM men after single bout of exercise
-
Devlin JT, Hirshman M, Horton ED, et al. Enhanced peripheral and splanchnic insulin sensitivity in NIDDM men after single bout of exercise. Diabetes 1987; 36: 434-9
-
(1987)
Diabetes
, vol.36
, pp. 434-439
-
-
Devlin, J.T.1
Hirshman, M.2
Horton, E.D.3
-
70
-
-
0022386539
-
Effects of prior high-intensity exercise on glucose metabolism in normal and insulin-resistant men
-
Devlin JT, Horton ES. Effects of prior high-intensity exercise on glucose metabolism in normal and insulin-resistant men. Diabetes 1985; 34: 973-9
-
(1985)
Diabetes
, vol.34
, pp. 973-979
-
-
Devlin, J.T.1
Horton, E.S.2
-
71
-
-
0342314436
-
Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients
-
Ryysy L, Hakkinen AM, Goto T, et al. Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients. Diabetes 2000; 49: 749-58
-
(2000)
Diabetes
, vol.49
, pp. 749-758
-
-
Ryysy, L.1
Hakkinen, A.M.2
Goto, T.3
-
72
-
-
0030740659
-
Therapeutic effects of restricted diet and exercise in obese patients with fatty liver
-
Ueno T, Sugawara H, Sujaku K, et al. Therapeutic effects of restricted diet and exercise in obese patients with fatty liver. J Hepatol 1997; 27: 103-7
-
(1997)
J Hepatol
, vol.27
, pp. 103-107
-
-
Ueno, T.1
Sugawara, H.2
Sujaku, K.3
-
73
-
-
0032958218
-
Short-term effects of exercise on plasma very low density lipoproteins (VLDL) and fatty acids
-
Borsheim E, Knardahl S, Hostmark AT. Short-term effects of exercise on plasma very low density lipoproteins (VLDL) and fatty acids. Med Sci Sports Exerc 1999; 31: 522-30
-
(1999)
Med Sci Sports Exerc
, vol.31
, pp. 522-530
-
-
Borsheim, E.1
Knardahl, S.2
Hostmark, A.T.3
-
74
-
-
0020410451
-
Fatty acid oxidation by liver and muscle preparations of exhaustively exercised rats
-
Barakat HA, Kasperek GJ, Dohm GL, et al. Fatty acid oxidation by liver and muscle preparations of exhaustively exercised rats. Biochem J 1982; 208: 419-24
-
(1982)
Biochem J
, vol.208
, pp. 419-424
-
-
Barakat, H.A.1
Kasperek, G.J.2
Dohm, G.L.3
-
75
-
-
0023893873
-
Effect of prolonged exercise on the level of triglycerides in the rat liver
-
Gorski J, Nowacka M, Namiot Z, et al. Effect of prolonged exercise on the level of triglycerides in the rat liver. Eur J Appl Physiol Occup Physiol 1988; 57: 554-7
-
(1988)
Eur J Appl Physiol Occup Physiol
, vol.57
, pp. 554-557
-
-
Gorski, J.1
Nowacka, M.2
Namiot, Z.3
-
76
-
-
0018931882
-
The post-exercise recovery of triglycerides in rat tissues
-
Gorski J, Kiryluk T. The post-exercise recovery of triglycerides in rat tissues. Eur J Appl Physiol Occup Physiol 1980; 45: 33-41
-
(1980)
Eur J Appl Physiol Occup Physiol
, vol.45
, pp. 33-41
-
-
Gorski, J.1
Kiryluk, T.2
-
77
-
-
0036300538
-
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha
-
Itani SI, Ruderman NB, Schmieder F, et al. Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha. Diabetes 2002; 51: 2005-11
-
(2002)
Diabetes
, vol.51
, pp. 2005-2011
-
-
Itani, S.I.1
Ruderman, N.B.2
Schmieder, F.3
-
78
-
-
0020636516
-
Metabolic control of hepatic gluconeogenesis during exercise
-
Dohm GL, Newsholme EA. Metabolic control of hepatic gluconeogenesis during exercise. Biochem J 1983; 212: 633-9
-
(1983)
Biochem J
, vol.212
, pp. 633-639
-
-
Dohm, G.L.1
Newsholme, E.A.2
-
79
-
-
3042558990
-
Effect of muscular exercise and glycogen depletion on rat liver and kidney phosphoenolpyruvate carboxykinase
-
Sanchez-Medina F, Sanchez-Urrutia L, Medina JM, et al. Effect of muscular exercise and glycogen depletion on rat liver and kidney phosphoenolpyruvate carboxykinase. FEBS Lett 1971; 19: 128-30
-
(1971)
FEBS Lett
, vol.19
, pp. 128-130
-
-
Sanchez-Medina, F.1
Sanchez-Urrutia, L.2
Medina, J.M.3
-
80
-
-
0024563492
-
Effects of long-term feeding of highprotein or high-fat diets on the response to exercise in the rat
-
Satabin P, Bois-Joyeux B, Chanez M, et al. Effects of long-term feeding of highprotein or high-fat diets on the response to exercise in the rat. Eur J Appl Physiol Occup Physiol 1989; 58: 583-90
-
(1989)
Eur J Appl Physiol Occup Physiol
, vol.58
, pp. 583-590
-
-
Satabin, P.1
Bois-Joyeux, B.2
Chanez, M.3
-
81
-
-
0028231673
-
Role of glucocorticoids in activation of hepatic PEPCK gene transcription during exercise
-
Friedman JE. Role of glucocorticoids in activation of hepatic PEPCK gene transcription during exercise. Am J Physiol 1994; 266: E560-6
-
(1994)
Am J Physiol
, vol.266
-
-
Friedman, J.E.1
-
82
-
-
0033016641
-
Liver AMP-activated protein kinase and acetyl-CoA carboxylase during and after exercise
-
Carlson CL, Winder WW. Liver AMP-activated protein kinase and acetyl-CoA carboxylase during and after exercise. J Appl Physiol 1999; 86: 669-74
-
(1999)
J Appl Physiol
, vol.86
, pp. 669-674
-
-
Carlson, C.L.1
Winder, W.W.2
-
83
-
-
0024209883
-
Effects of endurance exercise on carnitine palmitoyltransferase I from rat heart, skeletal muscle and liver mitochondria
-
Guzman M, Castro J. Effects of endurance exercise on carnitine palmitoyltransferase I from rat heart, skeletal muscle and liver mitochondria. Biochim Biophys Acta 1988; 963: 562-5
-
(1988)
Biochim Biophys Acta
, vol.963
, pp. 562-565
-
-
Guzman, M.1
Castro, J.2
-
84
-
-
0034843401
-
Exercise down-regulates hepatic fatty acid synthase in streptozotocin-treated rats
-
Fiebig RG, Hollander JM, Ji LL. Exercise down-regulates hepatic fatty acid synthase in streptozotocin-treated rats. J Nutr 2001; 131: 2252-9
-
(2001)
J Nutr
, vol.131
, pp. 2252-2259
-
-
Fiebig, R.G.1
Hollander, J.M.2
Ji, L.L.3
-
85
-
-
0016710115
-
Effect of exercise on response of liver lipogenic enzymes to a high fructose diet
-
Winder WW, Booth FW, Fitts RH, et al. Effect of exercise on response of liver lipogenic enzymes to a high fructose diet. Proc Soc Exp Biol Med 1975; 148: 1150-4
-
(1975)
Proc Soc Exp Biol Med
, vol.148
, pp. 1150-1154
-
-
Winder, W.W.1
Booth, F.W.2
Fitts, R.H.3
-
86
-
-
0032511053
-
AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes
-
Foretz M, Carling D, Guichard C, et al. AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes. J Biol Chem 1998; 273: 14767-71
-
(1998)
J Biol Chem
, vol.273
, pp. 14767-14771
-
-
Foretz, M.1
Carling, D.2
Guichard, C.3
-
87
-
-
0021321296
-
Effects of physical training and diet therapy on carbohydrate metabolism in patients with glucose intolerance and non-insulin-dependent diabetes mellitus
-
Bogardus C, Ravussin E, Robbins DC, et al. Effects of physical training and diet therapy on carbohydrate metabolism in patients with glucose intolerance and non-insulin-dependent diabetes mellitus. Diabetes 1984; 33: 311-8
-
(1984)
Diabetes
, vol.33
, pp. 311-318
-
-
Bogardus, C.1
Ravussin, E.2
Robbins, D.C.3
-
89
-
-
0023675110
-
Physical training and changes in regional adipose tissue distribution
-
Despres JP, Tremblay A, Nadeau A, et al. Physical training and changes in regional adipose tissue distribution. Acta Med Scand Suppl 1988; 723: 205-12
-
(1988)
Acta Med Scand Suppl
, vol.723
, pp. 205-212
-
-
Despres, J.P.1
Tremblay, A.2
Nadeau, A.3
-
90
-
-
0027236677
-
Marked reduction of acyl-CoA synthetase activity and mRNA in intra-abdominal visceral fat by physical exercise
-
Shimomura I, Tokunaga K, Kotani K, et al. Marked reduction of acyl-CoA synthetase activity and mRNA in intra-abdominal visceral fat by physical exercise. Am J Physiol 1993; 265: E44-50
-
(1993)
Am J Physiol
, vol.265
-
-
Shimomura, I.1
Tokunaga, K.2
Kotani, K.3
-
91
-
-
0025901052
-
Reciprocal responses to exercise in hepatic ketogenesis and lipid secretion in the rat
-
Fukuda N, Tojho M, Hidaka T, et al. Reciprocal responses to exercise in hepatic ketogenesis and lipid secretion in the rat. Ann Nutr Metab 1991; 35: 233-41
-
(1991)
Ann Nutr Metab
, vol.35
, pp. 233-241
-
-
Fukuda, N.1
Tojho, M.2
Hidaka, T.3
-
92
-
-
0028023412
-
Influence of endurance training on the age-related decline in hepatic glyconeogenesis
-
Podolin DA, Pagliassotti MJ, Gleeson TT, et al. Influence of endurance training on the age-related decline in hepatic glyconeogenesis. Mech Ageing Dev 1994; 75: 81-93
-
(1994)
Mech Ageing Dev
, vol.75
, pp. 81-93
-
-
Podolin, D.A.1
Pagliassotti, M.J.2
Gleeson, T.T.3
-
93
-
-
0020344939
-
Influence of physical training on insulin release and glucose utilization by islet cells and liver glucokinase activity in the rat
-
Zawalich W, Maturo S, Felig P. Influence of physical training on insulin release and glucose utilization by islet cells and liver glucokinase activity in the rat. Am J Physiol 1982; 243: E464-9
-
(1982)
Am J Physiol
, vol.243
-
-
Zawalich, W.1
Maturo, S.2
Felig, P.3
-
94
-
-
0035986085
-
Invited review: Intracellular signaling in contracting skeletal muscle
-
Sakamoto K, Goodyear LJ. Invited review: intracellular signaling in contracting skeletal muscle. J Appl Physiol 2002; 93: 369-83
-
(2002)
J Appl Physiol
, vol.93
, pp. 369-383
-
-
Sakamoto, K.1
Goodyear, L.J.2
-
95
-
-
0036214110
-
Modulation of insulin signaling in human skeletal muscle in response to exercise
-
Kirwan JP, Jing M. Modulation of insulin signaling in human skeletal muscle in response to exercise. Exerc Sport Sci Rev 2002; 30: 85-90
-
(2002)
Exerc Sport Sci Rev
, vol.30
, pp. 85-90
-
-
Kirwan, J.P.1
Jing, M.2
-
96
-
-
0033968126
-
Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle
-
Cusi K, Maezono K, Osman A, et al. Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle. J Clin Invest 2000; 105: 311-20
-
(2000)
J Clin Invest
, vol.105
, pp. 311-320
-
-
Cusi, K.1
Maezono, K.2
Osman, A.3
-
97
-
-
0033977444
-
Regular exercise enhances insulin activation of IRS-1-associated PI3-kinase in human skeletal muscle
-
Kirwan JP, del Aguila LF, Hernandez JM, et al. Regular exercise enhances insulin activation of IRS-1-associated PI3-kinase in human skeletal muscle. J Appl Physiol 2000; 88: 797-803
-
(2000)
J Appl Physiol
, vol.88
, pp. 797-803
-
-
Kirwan, J.P.1
Del Aguila, L.F.2
Hernandez, J.M.3
-
98
-
-
0033373480
-
Effect of short-term exercise training on insulin-stimulated PI 3-kinase activity in human skeletal muscle
-
Houmard JA, Shaw CD, Hickey MS, et al. Effect of short-term exercise training on insulin-stimulated PI 3-kinase activity in human skeletal muscle. Am J Physiol 1999; 277: E1055-60
-
(1999)
Am J Physiol
, vol.277
-
-
Houmard, J.A.1
Shaw, C.D.2
Hickey, M.S.3
-
99
-
-
0022547759
-
Chronic exercise increases insulin binding in muscles but not liver
-
Bonen A, Clune PA, Tan MH. Chronic exercise increases insulin binding in muscles but not liver. Am J Physiol 1986; 251: E196-203
-
(1986)
Am J Physiol
, vol.251
-
-
Bonen, A.1
Clune, P.A.2
Tan, M.H.3
|