Signalling through the insulin receptor

Current Opinion in Cell Biology

Volumn 12, Issue 2, 2000, Pages 222-228

  Whitehead, Jonathan P ^a   Clark, Sharon F ^a   Ursø, Birgitte ^b   James, David E ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2;

CYTOSKELETON; INSULIN RESISTANCE; INSULIN SENSITIVITY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVIEW; SIGNAL TRANSDUCTION;

EID: 0034009229     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-0674(99)00079-4     Document Type: Review

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66. •].
67. •].
68. •] provide considerable evidence supporting a role for the atypical PKCs (ζ/λ), in insulin-stimulated glucose uptake.
69. •] the authors show that insulin stimulates PIP3 production at the plasma membrane to a greater magnitude and in more cells than PDGF, consistent with the findings in [43].
70. -/- and wild-type mice may be due to alterations in hypothalamic function, where high levels of IRS-4 mRNA have been detected.