-
1
-
-
0034467660
-
5-HT and human anxiety. Evidence from studies using acute tryptophan depletion
-
Anderson I.M., Mortimore C. 5-HT and human anxiety. Evidence from studies using acute tryptophan depletion. Adv. Exp. Med. Biol. 467:1999;43-55.
-
(1999)
Adv. Exp. Med. Biol.
, vol.467
, pp. 43-55
-
-
Anderson, I.M.1
Mortimore, C.2
-
2
-
-
0342829315
-
Post mortem human brain tissue investigations of neurotransmitters in ageing and in AD/SDAT
-
C. Racagni, N. Brunelo, & T. Fukada. Amsterdam: Excerpta Medica
-
Arai H., Takahashi T., Kimura M., Noguchi I., Minami M., Iizuka R. Post mortem human brain tissue investigations of neurotransmitters in ageing and in AD/SDAT. Racagni C., Brunelo N., Fukada T. Biological Psychiatry. 1991;131-133 Excerpta Medica, Amsterdam.
-
(1991)
Biological Psychiatry
, pp. 131-133
-
-
Arai, H.1
Takahashi, T.2
Kimura, M.3
Noguchi, I.4
Minami, M.5
Iizuka, R.6
-
3
-
-
0015837338
-
Tests for emotionality in rats and mice: A review
-
Archer J. Tests for emotionality in rats and mice a review . Animal Behaviour. 21:1973;205-235.
-
(1973)
Animal Behaviour
, vol.21
, pp. 205-235
-
-
Archer, J.1
-
4
-
-
0036318339
-
SWE transgenic mice
-
SWE transgenic mice. Mol. Cell. Neurosci. 20:2002;354-365.
-
(2002)
Mol. Cell. Neurosci.
, vol.20
, pp. 354-365
-
-
Bednar, I.1
Paterson, D.2
Marutle, A.3
Pham, T.M.4
Svedberg, M.5
Hellstrom-Lindahl, E.6
Mousavi, M.7
Court, J.8
Morris, C.9
Perry, E.10
Mohammed, A.11
Zhang, X.12
Nordberg, A.13
-
5
-
-
0035127216
-
Putative mechanisms of action of antidepressant drugs in affective and anxiety disorders and pain
-
Blier P., Abbott F.V. Putative mechanisms of action of antidepressant drugs in affective and anxiety disorders and pain. J. Psych. Neurosci. 26:2001;37-43.
-
(2001)
J. Psych. Neurosci.
, vol.26
, pp. 37-43
-
-
Blier, P.1
Abbott, F.V.2
-
6
-
-
0036315584
-
Expression of human β-secretase in the mouse brain increases the steady-state level of β-amyloid
-
Bodendorf U., Danner S., Fischer F., Stefani M., Sturchler-Pierrat C., Weiderhold K.-H., Staufenbiel M., Paganetti P. Expression of human β-secretase in the mouse brain increases the steady-state level of β-amyloid. J. Neurochem. 80:2002;799-806.
-
(2002)
J. Neurochem.
, vol.80
, pp. 799-806
-
-
Bodendorf, U.1
Danner, S.2
Fischer, F.3
Stefani, M.4
Sturchler-Pierrat, C.5
Weiderhold, K.-H.6
Staufenbiel, M.7
Paganetti, P.8
-
7
-
-
0037080160
-
Amyloid-associated neuron loss and gliogenesis in the neocortex of amyloid precursor protein transgenic mice
-
Bondolfi L., Calhoun M., Ermini F., Kuhn H.G., Wiederhold K.H., Walker L., Staufenbiel M., Jucker M. Amyloid-associated neuron loss and gliogenesis in the neocortex of amyloid precursor protein transgenic mice. J. Neurosci. 22:2002;515-522.
-
(2002)
J. Neurosci.
, vol.22
, pp. 515-522
-
-
Bondolfi, L.1
Calhoun, M.2
Ermini, F.3
Kuhn, H.G.4
Wiederhold, K.H.5
Walker, L.6
Staufenbiel, M.7
Jucker, M.8
-
8
-
-
0035112647
-
BACE1 is the major beta-secretase for generation of Abeta peptides by neurons
-
Cai H., Wang Y., McCarthy D., Wen H., Borchelt D.R., Price D.L., Wong P.C. BACE1 is the major beta-secretase for generation of Abeta peptides by neurons. Nat. Neurosci. 4:2001;233-234.
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 233-234
-
-
Cai, H.1
Wang, Y.2
Mccarthy, D.3
Wen, H.4
Borchelt, D.R.5
Price, D.L.6
Wong, P.C.7
-
9
-
-
0021891119
-
Cortical neurons immunoreactive with antisera against neuropeptide Y are altered in Alzheimer's-type dementia
-
Chan-Palay V., Lang W., Allen Y.S., Haesler U., Polak J.M. Cortical neurons immunoreactive with antisera against neuropeptide Y are altered in Alzheimer's-type dementia. J. Comp. Neurol. 238:1985;390-400.
-
(1985)
J. Comp. Neurol.
, vol.238
, pp. 390-400
-
-
Chan-Palay, V.1
Lang, W.2
Allen, Y.S.3
Haesler, U.4
Polak, J.M.5
-
10
-
-
0033360356
-
Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice
-
Chapman P.F., White G.L., Jones M.W., Cooper-Blacketer D., Marshall V.J., Irizarry M., Younkin L., Good M.A., Bliss T.V.P., Hyman B.T., Younkin S.G., Hsiao K.K. Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. Nat. Neurosci. 2:1999;271-276.
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 271-276
-
-
Chapman, P.F.1
White, G.L.2
Jones, M.W.3
Cooper-Blacketer, D.4
Marshall, V.J.5
Irizarry, M.6
Younkin, L.7
Good, M.A.8
Bliss, T.V.P.9
Hyman, B.T.10
Younkin, S.G.11
Hsiao, K.K.12
-
11
-
-
0031925702
-
The role of serotonin in depression and anxiety
-
Deakin J.F.W. The role of serotonin in depression and anxiety. Eur. Psychiat. 13:(S2):1998;57s-63s.
-
(1998)
Eur. Psychiat.
, vol.13
, Issue.S2
-
-
Deakin, J.F.W.1
-
12
-
-
0034648738
-
Neuropepotides in hippocampus and cortex in transgenic mice overexpressing V717F β-amyloid precursor protein - Initial observations
-
Diez M., Koistinaho J., Kahn K., Games D., Hokfelt T. Neuropepotides in hippocampus and cortex in transgenic mice overexpressing V717F β-amyloid precursor protein - initial observations. Neuroscience. 100:2000;259-286.
-
(2000)
Neuroscience
, vol.100
, pp. 259-286
-
-
Diez, M.1
Koistinaho, J.2
Kahn, K.3
Games, D.4
Hokfelt, T.5
-
13
-
-
0038664363
-
Reconstitution of γ-secretase activity
-
Edbauer D., Winkler E., Regula J.T., Pesold B., Steiner H., Haass C. Reconstitution of γ-secretase activity. Nat. Cell Biol. 5:2003;486-488.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 486-488
-
-
Edbauer, D.1
Winkler, E.2
Regula, J.T.3
Pesold, B.4
Steiner, H.5
Haass, C.6
-
15
-
-
0033982103
-
Alzheimer disease: Mouse models pave the way for therapeutic opportunities
-
Emilien G., Maloteaux J.M., Beyreuther K., Masters C.L. Alzheimer disease mouse models pave the way for therapeutic opportunities . Arch. Neurol. 57:2000;176-181.
-
(2000)
Arch. Neurol.
, vol.57
, pp. 176-181
-
-
Emilien, G.1
Maloteaux, J.M.2
Beyreuther, K.3
Masters, C.L.4
-
16
-
-
0030499463
-
Pyramidal neurone modulation: A therapeutic target for Alzheimer's disease
-
Francis P.T. Pyramidal neurone modulation a therapeutic target for Alzheimer's disease . Neurodegeneration. 5:1996;461-465.
-
(1996)
Neurodegeneration
, vol.5
, pp. 461-465
-
-
Francis, P.T.1
-
17
-
-
0026664554
-
Animal and drug modelling for Alzheimer synaptic pathology
-
Francis P.T., Pangalos M.N., Bowen D.M. Animal and drug modelling for Alzheimer synaptic pathology. Prog. Neurobiol. 39:1992;517-545.
-
(1992)
Prog. Neurobiol.
, vol.39
, pp. 517-545
-
-
Francis, P.T.1
Pangalos, M.N.2
Bowen, D.M.3
-
18
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F Beta-amyloid precursor protein
-
Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C., Carr T., Clemens J., Donaldson T., Gillespie F., Guido T., Hagopian S., Johnson-wood K., Khan K., Lee M., Leibowitz P., Lieberburg I., Little S., Masliah E., Mcconlogue L., Montoya-zavala M., Mucke L., Paganini L., Penniman E., Power M., Schenk D., et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F Beta-amyloid precursor protein. Nature. 373:1995;523-527.
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
Guido, T.11
Hagopian, S.12
Johnson-Wood, K.13
Khan, K.14
Lee, M.15
Leibowitz, P.16
Lieberburg, I.17
Little, S.18
Masliah, E.19
Mcconlogue, L.20
Montoya-Zavala, M.21
Mucke, L.22
Paganini, L.23
Penniman, E.24
Power, M.25
Schenk, D.26
more..
-
19
-
-
0019983405
-
Effects of agents which enhance GABA-mediated neurotransmission on licking conflict in rats and exploration in mice
-
Gardner C.R., Piper D.C. Effects of agents which enhance GABA-mediated neurotransmission on licking conflict in rats and exploration in mice. Eur. J. Pharmacol. 83:1982;25-33.
-
(1982)
Eur. J. Pharmacol.
, vol.83
, pp. 25-33
-
-
Gardner, C.R.1
Piper, D.C.2
-
20
-
-
73049155988
-
The isolation of nerve endings from brain: An electron microscopic study of cell fragments derived by homogenisation and centrifugation
-
Gray E.G., Whittaker P. The isolation of nerve endings from brain an electron microscopic study of cell fragments derived by homogenisation and centrifugation . J. Anat. 96:1962;79-88.
-
(1962)
J. Anat.
, vol.96
, pp. 79-88
-
-
Gray, E.G.1
Whittaker, P.2
-
21
-
-
0037135111
-
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J., Selkoe D.J. Medicine - the amyloid hypothesis of Alzheimer's disease progress and problems on the road to therapeutics . Science. 297:2002;353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
22
-
-
0035947141
-
Survival and plasticity of basal forebrain cholinergic systems in mice transgenic for presenilin-1 and amyloid precursor protein mutant genes
-
Hernandez D., Sugaya K., Qu T., McGowan E., Duff K., McKinney M. Survival and plasticity of basal forebrain cholinergic systems in mice transgenic for presenilin-1 and amyloid precursor protein mutant genes. Neuroreport. 12:2001;1377-1384.
-
(2001)
Neuroreport
, vol.12
, pp. 1377-1384
-
-
Hernandez, D.1
Sugaya, K.2
Qu, T.3
Mcgowan, E.4
Duff, K.5
Mckinney, M.6
-
23
-
-
0003799070
-
Manipulating the Mouse Embryo: A Laboratory Manual
-
New York: Cold Spring Harbor Laboratory Press
-
Hogan B., Beddington R., Costantini F., Lacey E. Manipulating the Mouse Embryo A Laboratory Manual . second ed :1994;Cold Spring Harbor Laboratory Press, New York.
-
(1994)
second ed
-
-
Hogan, B.1
Beddington, R.2
Costantini, F.3
Lacey, E.4
-
24
-
-
0029742199
-
Correlative memory deficits, A-beta elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., Cole G. Correlative memory deficits, A-beta elevation, and amyloid plaques in transgenic mice. Science. 274:1996;99-103.
-
(1996)
Science
, vol.274
, pp. 99-103
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
25
-
-
0033382226
-
Identification of a novel aspartic protease (Asp2) as beta-secretase
-
Hussain I., Powell D., Howlett D.R., Tew D.G., Meek T.D., Chapman C., Gloger I.S., Murphy K.E., Southan C.D., Ryan D.M., Smith T.S., Simmons D.L., Walsh F.S., Dingwall C., Christie G. Identification of a novel aspartic protease (Asp2) as beta-secretase. Mol. Cell. Neurosci. 14:1999;419-427.
-
(1999)
Mol. Cell. Neurosci.
, vol.14
, pp. 419-427
-
-
Hussain, I.1
Powell, D.2
Howlett, D.R.3
Tew, D.G.4
Meek, T.D.5
Chapman, C.6
Gloger, I.S.7
Murphy, K.E.8
Southan, C.D.9
Ryan, D.M.10
Smith, T.S.11
Simmons, D.L.12
Walsh, F.S.13
Dingwall, C.14
Christie, G.15
-
26
-
-
0030611097
-
Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse
-
Irizarry M.C., Soriano F., McNamara M., Page K.J., Schenk D., Games D., Hyman B.T. Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse. J. Neurosci. 17:1997;7053-7059.
-
(1997)
J. Neurosci.
, vol.17
, pp. 7053-7059
-
-
Irizarry, M.C.1
Soriano, F.2
Mcnamara, M.3
Page, K.J.4
Schenk, D.5
Games, D.6
Hyman, B.T.7
-
28
-
-
0038652102
-
γ-Secretase is a membrane protein comples comprised of presenilin, nicastrin, aph-1 and pen-2
-
Kimberly W.T., LaVole M.J., Ostaszewski B.L., Ye W., Wolfe M.S., Selkoe D.J. γ-Secretase is a membrane protein comples comprised of presenilin, nicastrin, aph-1 and pen-2. Proc. Natl. Acad. Sci. USA. 100:2003;6382-6387.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 6382-6387
-
-
Kimberly, W.T.1
Lavole, M.J.2
Ostaszewski, B.L.3
Ye, W.4
Wolfe, M.S.5
Selkoe, D.J.6
-
29
-
-
0033199822
-
Progressive and gender-dependent cognitive impairment in the APPSW transgenic mouse model for Alzheimer's disease
-
King D.L., Arendash G.W., Crawford F., Sterka T., Menendeza J., Mullan M.J. Progressive and gender-dependent cognitive impairment in the APPSW transgenic mouse model for Alzheimer's disease. Behav. Brain Res. 103:1999;145-162.
-
(1999)
Behav. Brain Res.
, vol.103
, pp. 145-162
-
-
King, D.L.1
Arendash, G.W.2
Crawford, F.3
Sterka, T.4
Menendeza, J.5
Mullan, M.J.6
-
30
-
-
0035116273
-
Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation
-
Luo Y., Bolon B., Kahn S., Bennett B.D., Babu-Khan S., Denis P., Fan W., Kha H., Zhang J., Gong Y., Martin L., Louis J.C., Yan Q., Richards W.G., Citron M., Vassar R. Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation. Nat. Neurosci. 4:2001;231-232.
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 231-232
-
-
Luo, Y.1
Bolon, B.2
Kahn, S.3
Bennett, B.D.4
Babu-Khan, S.5
Denis, P.6
Fan, W.7
Kha, H.8
Zhang, J.9
Gong, Y.10
Martin, L.11
Louis, J.C.12
Yan, Q.13
Richards, W.G.14
Citron, M.15
Vassar, R.16
-
31
-
-
0033793248
-
Coordinated expression of beta-amyloid precursor protein and the putative beta-secretase BACE and alpha-secretase ADAM10 in mouse and human brain
-
Marcinkiewicz M., Seidah N.G. Coordinated expression of beta-amyloid precursor protein and the putative beta-secretase BACE and alpha-secretase ADAM10 in mouse and human brain. J. Neurochem. 75:2000;2133-2143.
-
(2000)
J. Neurochem.
, vol.75
, pp. 2133-2143
-
-
Marcinkiewicz, M.1
Seidah, N.G.2
-
32
-
-
0029807527
-
Control of memory formation through regulated expression of a CamKII transgene
-
Mayford M., Bach M.E., Huang Y.Y., Wang L., Hawkins R.D., Kandel E.R. Control of memory formation through regulated expression of a CamKII transgene. Science. 274:1996;1678-1683.
-
(1996)
Science
, vol.274
, pp. 1678-1683
-
-
Mayford, M.1
Bach, M.E.2
Huang, Y.Y.3
Wang, L.4
Hawkins, R.D.5
Kandel, E.R.6
-
33
-
-
0031944188
-
Serotonin in aging, late-life depression, and Alzheimers disease - The emerging role of functional imaging
-
Meltzer C.C., Smith G., DeKosky S.T., Pollock B.G., Mathis C.A., Moore R.Y., Kupfer D.J., Reynolds C.F. Serotonin in aging, late-life depression, and Alzheimers disease - the emerging role of functional imaging. Neuropsychopharmacology. 18:1998;407-430.
-
(1998)
Neuropsychopharmacology
, vol.18
, pp. 407-430
-
-
Meltzer, C.C.1
Smith, G.2
Dekosky, S.T.3
Pollock, B.G.4
Mathis, C.A.5
Moore, R.Y.6
Kupfer, D.J.7
Reynolds, C.F.8
-
34
-
-
0033525520
-
Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain
-
Moechars D., Dewachter I., Lorent K., Reverse D., Baekelandt V., Naidu A., Tesseur I., Spittaels K., Van Den Haute C., Checler F., Godaux E., Cordell B., Van Leuven F. Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain. J. Biologic. Chem. 274:1999;6483-6492.
-
(1999)
J. Biologic. Chem.
, vol.274
, pp. 6483-6492
-
-
Moechars, D.1
Dewachter, I.2
Lorent, K.3
Reverse, D.4
Baekelandt, V.5
Naidu, A.6
Tesseur, I.7
Spittaels, K.8
Van Den Haute, C.9
Checler, F.10
Godaux, E.11
Cordell, B.12
Van Leuven, F.13
-
35
-
-
0034213718
-
High-level neuronal expression of A beta(1-42) in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
-
Mucke L., Masliah E., Yu G.Q., Mallory M., Rockenstein E.M., Tatsuno G., Hu K., Kholodenko D., Johnson-Wood K., McConlogue L. High-level neuronal expression of A beta(1-42) in wild-type human amyloid protein precursor transgenic mice synaptotoxicity without plaque formation . J. Neurosci. 20:2000;4050-4058.
-
(2000)
J. Neurosci.
, vol.20
, pp. 4050-4058
-
-
Mucke, L.1
Masliah, E.2
Yu, G.Q.3
Mallory, M.4
Rockenstein, E.M.5
Tatsuno, G.6
Hu, K.7
Kholodenko, D.8
Johnson-Wood, K.9
Mcconlogue, L.10
-
36
-
-
0038117796
-
Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline
-
Naslund J., Haroutunian V., Mohs R., Davis K.L., Davies P., Greengard P., Buxbaum J.D. Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. JAMA. 283:2000;1571-1577.
-
(2000)
JAMA
, vol.283
, pp. 1571-1577
-
-
Naslund, J.1
Haroutunian, V.2
Mohs, R.3
Davis, K.L.4
Davies, P.5
Greengard, P.6
Buxbaum, J.D.7
-
37
-
-
0033082456
-
Adaptation of the circular platform spatial memory task for mice: Use in detecting cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease
-
Pompl P.N., Mullan M.J., Bjugstad K., Arendash G.W. Adaptation of the circular platform spatial memory task for mice use in detecting cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease . J. Neurosci. Methods. 87:1999;87-95.
-
(1999)
J. Neurosci. Methods
, vol.87
, pp. 87-95
-
-
Pompl, P.N.1
Mullan, M.J.2
Bjugstad, K.3
Arendash, G.W.4
-
38
-
-
0034948116
-
Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice
-
Prosser H.M., Gill C.H., Hirst W.D., Grau E., Robbins M., Calver A., Soffin E.M., Farmer C.E., Lanneau C., Gray J., Schenck E., Warmerdam B.S., Clapham C., Reavill C., Rogers D.C., Stean T., Upton N., Humphreys K., Randall A., Geppert M., Davies C.H., Pangalos M.N. Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice. Mol. Cell. Neurosci. 17:2001;1059-1070.
-
(2001)
Mol. Cell. Neurosci.
, vol.17
, pp. 1059-1070
-
-
Prosser, H.M.1
Gill, C.H.2
Hirst, W.D.3
Grau, E.4
Robbins, M.5
Calver, A.6
Soffin, E.M.7
Farmer, C.E.8
Lanneau, C.9
Gray, J.10
Schenck, E.11
Warmerdam, B.S.12
Clapham, C.13
Reavill, C.14
Rogers, D.C.15
Stean, T.16
Upton, N.17
Humphreys, K.18
Randall, A.19
Geppert, M.20
Davies, C.H.21
Pangalos, M.N.22
more..
-
39
-
-
0019223566
-
Acetylcholine and choline levels in post-mortem human brain tissue: Preliminary observations in Alzheimer's disease
-
Richter J.A., Perry E.K., Tomlinson B.E. Acetylcholine and choline levels in post-mortem human brain tissue preliminary observations in Alzheimer's disease . Life Sci. 26:1980;1683-1689.
-
(1980)
Life Sci.
, vol.26
, pp. 1683-1689
-
-
Richter, J.A.1
Perry, E.K.2
Tomlinson, B.E.3
-
40
-
-
0035928732
-
Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts
-
Riddell D.R., Christie G., Hussain I., Dingwall C. Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts. Curr. Biol. 11:2001;1288-1293.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1288-1293
-
-
Riddell, D.R.1
Christie, G.2
Hussain, I.3
Dingwall, C.4
-
41
-
-
17344388652
-
BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: Implications for Alzheimer's disease therapeutics
-
Roberds S.L., Anderson J., Basi G., Bienkowski M.J., Branstetter D.G., Chen K.S., Freedman S.B., Frigon N.L., Games D., Hu K., Johnson-Wood K., Kappenman K.E., Kawabe T.T., Kola I., Kuehn R., Lee M., Liu W., Motter R., Nichols N.F., Power M., Robertson D.W., Schenk D., Schoor M., Shopp G.M., Shuck M.E., Sinha S., Svensson K.A., Tatsuno G., Tintrup H., Wijsman J., Wright S., McConlogue L. BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain implications for Alzheimer's disease therapeutics . Human Mol. Genet. 10:2001;1317-1324.
-
(2001)
Human Mol. Genet.
, vol.10
, pp. 1317-1324
-
-
Roberds, S.L.1
Anderson, J.2
Basi, G.3
Bienkowski, M.J.4
Branstetter, D.G.5
Chen, K.S.6
Freedman, S.B.7
Frigon, N.L.8
Games, D.9
Hu, K.10
Johnson-Wood, K.11
Kappenman, K.E.12
Kawabe, T.T.13
Kola, I.14
Kuehn, R.15
Lee, M.16
Liu, W.17
Motter, R.18
Nichols, N.F.19
Power, M.20
Robertson, D.W.21
Schenk, D.22
Schoor, M.23
Shopp, G.M.24
Shuck, M.E.25
Sinha, S.26
Svensson, K.A.27
Tatsuno, G.28
Tintrup, H.29
Wijsman, J.30
Wright, S.31
Mcconlogue, L.32
more..
-
42
-
-
0031255352
-
Behavioural and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment
-
Rogers D.C., Fisher E.M., Brown S.D., Peters J., Hunter A.J., Martin J.E. Behavioural and functional analysis of mouse phenotype SHIRPA, a proposed protocol for comprehensive phenotype assessment . Mammalian Genome. 8:1997;711-713.
-
(1997)
Mammalian Genome
, vol.8
, pp. 711-713
-
-
Rogers, D.C.1
Fisher, E.M.2
Brown, S.D.3
Peters, J.4
Hunter, A.J.5
Martin, J.E.6
-
43
-
-
0030779784
-
Skeletal and CNS defects in Presenilin-1-deficient mice
-
Shen J., Bronson R.T., Chen D.F., Xia W., Selkoe D.J., Tonegawa S. Skeletal and CNS defects in Presenilin-1-deficient mice. Cell. 89:1997;629-639.
-
(1997)
Cell
, vol.89
, pp. 629-639
-
-
Shen, J.1
Bronson, R.T.2
Chen, D.F.3
Xia, W.4
Selkoe, D.J.5
Tonegawa, S.6
-
44
-
-
0029935765
-
Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons
-
Simons M., De Strooper B., Multhaup G., Tienari P.J., Dotti C.G., Beyreuther K. Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons. J. Neurosci. 16:1996;899-908.
-
(1996)
J. Neurosci.
, vol.16
, pp. 899-908
-
-
Simons, M.1
De Strooper, B.2
Multhaup, G.3
Tienari, P.J.4
Dotti, C.G.5
Beyreuther, K.6
-
45
-
-
0033518251
-
Purification and cloning of amyloid precursor protein beta-secretase from human brain
-
Sinha S., Anderson J.P., Barbour R., Basi G.S., Caccavello R., Davis D., Doan M., Dovey H.F., Frigon N., Hong J., Jacobson-Croak K., Jewett N., Keim P., Knops J., Lieberburg I., Power M., Tan H., Tatsuno G., Tung J., Schenk D., Seubert P., Suomensaari S.M., Wang S., Walker D., John V. Purification and cloning of amyloid precursor protein beta-secretase from human brain. Nature. 402:1999;537-540.
-
(1999)
Nature
, vol.402
, pp. 537-540
-
-
Sinha, S.1
Anderson, J.P.2
Barbour, R.3
Basi, G.S.4
Caccavello, R.5
Davis, D.6
Doan, M.7
Dovey, H.F.8
Frigon, N.9
Hong, J.10
Jacobson-Croak, K.11
Jewett, N.12
Keim, P.13
Knops, J.14
Lieberburg, I.15
Power, M.16
Tan, H.17
Tatsuno, G.18
Tung, J.19
Schenk, D.20
Seubert, P.21
Suomensaari, S.M.22
Wang, S.23
Walker, D.24
John, V.25
more..
-
46
-
-
0032923739
-
Generalised LacZ expression with the ROSA26 Cre reporter strain
-
Soriano P. Generalised LacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21:1999;70-71.
-
(1999)
Nat. Genet.
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
47
-
-
0030071206
-
Monoaminergic neurotransmitters, their precursors and metabolites in brains of Alzheimer patients
-
Storga D., Vrecko K., Birkmayer J.G.D., Reibnegger G. Monoaminergic neurotransmitters, their precursors and metabolites in brains of Alzheimer patients. Neurosci. Lett. 203:1996;29-32.
-
(1996)
Neurosci. Lett.
, vol.203
, pp. 29-32
-
-
Storga, D.1
Vrecko, K.2
Birkmayer, J.G.D.3
Reibnegger, G.4
-
48
-
-
0034014950
-
Single and multiple transgenic mice as models for Alzheimer's disease
-
van Leuven F. Single and multiple transgenic mice as models for Alzheimer's disease. Prog. Neurobiol. 61:2000;305-312.
-
(2000)
Prog. Neurobiol.
, vol.61
, pp. 305-312
-
-
Van Leuven, F.1
-
49
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R., Bennett B.D., Babu-Khan S., Kahn S., Mendiaz E.A., Denis P., Teplow D.B., Ross S., Amarante P., Loeloff R., Luo Y., Fisher S., Fuller J., Edenson S., Lile J., Jarosinski M.A., Biere A.L., Curran E., Burgess T., Louis J.C., Collins F., Treanor J., Rogers G., Citron M. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science. 286:1999;735-741.
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
50
-
-
0033989793
-
Measurement of anxiety in transgenic mice
-
Weiss S.M., Lightowler S., Stanhope K.J., Kennett G.A., Dourish C.T. Measurement of anxiety in transgenic mice. Rev. Neurosci. 11:2000;59-74.
-
(2000)
Rev. Neurosci.
, vol.11
, pp. 59-74
-
-
Weiss, S.M.1
Lightowler, S.2
Stanhope, K.J.3
Kennett, G.A.4
Dourish, C.T.5
-
51
-
-
0033518264
-
Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity
-
Yan R., Bienkowski M.J., Shuck M.E., Miao H., Tory M.C., Pauley A.M., Brashier J.R., Stratman N.C., Mathews W.R., Buhl A.E., Carter D.B., Tomasselli A.G., Parodi L.A., Heinrikson R.L., Gurney M.E. Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity. Nature. 402:1999;533-537.
-
(1999)
Nature
, vol.402
, pp. 533-537
-
-
Yan, R.1
Bienkowski, M.J.2
Shuck, M.E.3
Miao, H.4
Tory, M.C.5
Pauley, A.M.6
Brashier, J.R.7
Stratman, N.C.8
Mathews, W.R.9
Buhl, A.E.10
Carter, D.B.11
Tomasselli, A.G.12
Parodi, L.A.13
Heinrikson, R.L.14
Gurney, M.E.15
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