Monoaminergic neurotransmitters, their precursors and metabolites in brains of Alzheimer patients

Neuroscience Letters

Volumn 203, Issue 1, 1996, Pages 29-32

  Storga, D ^a   Vrecko, K ^a   Birkmayer, J G D ^b   Reibnegger, G ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b Lehr und Forschungseinrichtung BIPT   (Austria)

Author keywords

5 Hydroxytryptamine; Alzheimer's disease; Catecholamines; Postmortem brain; Tryptophan; Tyrosine

Indexed keywords

CATECHOLAMINE; LEVODOPA; SEROTONIN; TRYPTOPHAN; TYROSINE;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; MALE; MONOAMINE METABOLISM; PRIORITY JOURNAL;

EID: 0030071206     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(95)12256-7     Document Type: Article

References (20)

1. Adolfsson, R., Gottfries, C.G., Ross, B.E. and Winbald, B., Changes in the brain catecholamines in patients with dementia of Alzheimer type. Br. J. Psychiatry, 135 (1979) 216-223.
2. 3H]GBR-12935 in Alzheimer's disease, Eur. Neurol., 30 (1990) 181-185.
3. Arai, H., Kosaka, K. and Iizuka, R., Changes of biogenic amines and their metabolites in postmortem brains from patients with Alzheimer-type dementia, J. Neurochem., 43 (1984) 388-393.
4. Bierer, L.M., Haroutunian, V., Gabriel, S., Knott, P.J., Carlin, L.S., Purohit, D.P., Perl, D.P., Schmeidler, J., Kanof, P. and Davis, K.L., Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits, J. Neurochem., 64 (1995) 749-760.
5. Birkmayer, J.G.D., The coenzyme nicocinamide adenine dinucleotide, the new therapeutic approach for improving dementia of the Alzheimer type, Ann. Clin. Lab. Sci., 25 (1995) in press.
6. Cross, A.J., Crow, T.J., Perry, E.K., Perry, R.H., Blessed, G. and Tomlinson, B.E., Reduced dopamine-beta hydroxylase activity in Alzheimer's disease, Br. Med. J., 282 (1981) 93-94.
7. Cross, A.J., Crow, T.J., Johnson, J.A., Joseph, M.H., Perry, E.K., Perry, R.H., Blessed, G. and Tomlinson, B.E., Monoamine metabolism in senile dementia of Alzheimer type, J. Neurol. Sci., 60 (1983) 383-392.
8. Gottfries, C.G., Pharmacology of mental aging and dementia disorders, Clin. Neuropharmacol., 10 (1987) 313-329.
9. Jossan, S.S., Gillberg, P.G., Gottfries, C.G., Karlsson, I. and Oreland, L., Monoamine oxidase B in brains from patients with Alzheimer's disease: a biochemical and autoradiographical study, Neuroscience, 45 (1991) 1-12.
10. Kopelman, M.D., The cholinergic neurotransmitter system in human memory and dementia, Q. J. Exp. Psychol., 38A (1986) 535-573.
11. Mann, D.M.A, Yates, P.O. and Hawkes, J., The noradrenergic system in Alzheimer and multiinfarct dementias, J. Neurol. Neurosurg. Psychiatry, 45 (1982) 113-119.
12. Martinez, M., Frank, A., Dieztejedor, E. and Hernanz, A., Amino-acid concentrations in cerebrospinal fluid and serum in Alzheimer's disease and vascular dementia, J. Neural Transm. (P-D Sect.), 6 (1993) 1-9.
13. Nazarali, A.J. and Reynolds, G.P., Monoamine neurotransmitters and their metabolites in brain regions in Alzheimer's disease: a postmortem study, Cell. Mol. Neurobiol., 12 (1992) 581-587.
14. Palmer, A.M., Wilcock, G.K., Esiri, M.M., Francis, P.T. and Bowen, D.M., Monoaminergic innervation of the frontal and temporal lobes in Alzheimer's disease, Brain Res., 401 (1987) 231-238.
15. Regland, B., Alzheimer's disease and senile dementia: biochemical characteristics. In M. Nicolini, P.F. Zatta and B. Corain (Eds.), Alzheimer's Disease and Related Disorders, Advances in the Biosciences, Vol. 87, Pergamon Press, Oxford, 1993, pp. 441-444.
16. Reinikainen, K.J., Soininen, H. and Riekkinen, P.J., Neurotransmitter changes in Alzheimer's disease: implications to diagnostics and therapy, J. Neurosci. Res., 27 (1990) 576-586.
17. Sawada, M., Hirata, Y., Arai, H., Iizuka, R. and Nagatsu, T., Tyrosine hydroxylase, tryptophan hydroxylase, biopterin, and neopterin in brains of normal controls and patients with senile dementia of Alzheimer type, J. Neurochem., 48 (1987) 760-764.
18. Spokes, E.G.S., An analysis of factors influencing measurements of dopamine, noradrenaline, glutamate decarboxylase and choline acetylase in human postmortem brain tissue, Brain, 102 (1979) 333-346.
19. Vrecko, K., Birkmayer, J.G.D. and Krainz, J., Stimulation of dopamine biosynthesis in cultured PC12 pheochromocytoma cells by the coenzyme nicotinamide adenine dinucleotide (NADH), J. Neural Transm. (P-D Sect.), 5 (1993) 147-156.
20. Yang, J.C., Liu, T.Y., Chang, Y.F., Liu, H.C., Shih, Y.H., Lee, L.S. and Chi, C.W., Simultaneous determination of fourteen catecholamines and their metabolites by high performance liquid chromatography with electrochemical detection, J. Liquid Chromatogr., 14 (1991) 3559-3573.