Dynorphin A (1-17) induces apoptosis in striatal neurons in vitro through α-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor-mediated cytochrome C release and caspase-3 activation

Neuroscience

Volumn 122, Issue 4, 2003, Pages 1013-1023

  Singh, I N ^a   Goody, R J ^a   Goebel, S M ^a   Martin, K M ^a   Knapp, P E ^a   Marinova, Z ^b   Hirschberg, D ^b   Yakovleva, T ^b   Bergman, T ^b   Bakalkin, G ^b   Hauser, K F ^a,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

AMPA receptors; CX546; Drug abuse; Neurotoxicity; NMDA receptors; Opioid receptors

Indexed keywords

1 (1,4 BENZODIOXAN 6 YLCARBONYL)PIPERIDINE; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; BENZYLOXYCARBONYLASPARTYLVALYLGLUTAMYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 3 INHIBITOR; CYTOCHROME C; DIZOCILPINE; DIZOCILPINE MALEATE; DYNORPHIN A; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NALOXONE; OPIATE ANTAGONIST; OPIATE RECEPTOR; PIPERIDINE DERIVATIVE; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATTENUATION; CELL MEMBRANE PERMEABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYONAL TISSUE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; MITOCHONDRION; MOUSE; NERVE CELL; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL;

EID: 10744229214     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2003.08.033     Document Type: Article

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