DREAM is a critical transcriptional repressor for pain modulation

Cell

Volumn 108, Issue 1, 2002, Pages 31-43

  Cheng, Hai Ying M ^a,b,c,d   Pitcher, Graham M ^f,g   Laviolette, Steven R ^h   Whishaw, Ian Q ⁱ   Tong, Kit I ^c,d   Kockeritz, Lisa K ^c,d   Wada, Teiji ^a,b   Joza, Nicholas A ^a,b,e   Crackower, Michael ^a,b,c   Goncalves, Jason ^c,d   Sarosi, Ildiko ^j   Woodgett, James R ^c,d   Oliveira dos Santos, Antonio J ^a,b   Ikura, Mitsuhiko ^c,d   Van der Kooy, Derek ^h   Salter, Michael W ^f,g   Penninger, Josef M ^a,b,c,d,e  

^a AMGEN INSTITUTE   (Canada)

^b INSTITUTE OF MOLECULAR BIOTECHNOLOGY   (Austria)

^c PRINCESS MARGARET HOSPITAL   (Canada)

^d Department of Medical Biophysics ^*  (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f HOSPITAL FOR SICK CHILDREN   (Canada)

^g UNIVERSITY OF TORONTO   (Canada)

^h UNIVERSITY OF TORONTO   (Canada)

ⁱ NeuroDetective Inc   (Canada)

^j AMGEN INC   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALSENILIN; DYNORPHIN A; KAPPA OPIATE RECEPTOR; MESSENGER RNA; PRODYNORPHIN; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BEHAVIOR; CHRONIC PAIN; CONTROLLED STUDY; EMBRYO; EXPERIMENTAL MODEL; GENE REPRESSION; INFLAMMATION; LEARNING; MECHANICAL STIMULATION; MEMORY; MOTOR PERFORMANCE; MOUSE; NEUROPATHY; NOCICEPTION; NONHUMAN; PAIN ASSESSMENT; PRIORITY JOURNAL; PROTEIN DEPLETION; REGULATORY MECHANISM; SPINAL CORD; THERMAL STIMULATION; TRANSCRIPTION REGULATION; VISCERAL PAIN;

ANIMALIA;

EID: 18244378838     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00629-8     Document Type: Article

References (58)

1. Antagonism of stimulation-produced analgesia by naloxone, a narcotic antagonist
2. Cloning and characterization of multiple opioid receptors
3. Modulation of A-type potassium channels by a family of calcium sensors
4. Agonist-induced phosphorylation of the κ-opioid receptor
5. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
6. Calsenilin: A calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment
7. Primary afferent tachykinins are required to experience moderate to intense pain
8. Protein kinase A-dependent derepression of the human prodynorphin gene via differential binding to an intragenic silencer element
9. 2+-regulated transcriptional repressor
10. κ 2 opioid receptors inhibit NMDA receptor-mediated synaptic currents in guinea pig CA3 pyramidal cells
11. Dynorphin block of N-methyl-D-aspartate channels increases with the peptide length
12. The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphin
13. Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2
14. Estrogen and progesterone activate spinal κ-opiate receptor analgesic mechanisms
15. Mechanisms of the analgesic actions of opiates and opioids
16. The D2 receptor is critical in mediating opiate motivation only in opiate-dependent and withdrawn mice
17. The molecular evolution of neuropeptides: Prospects for the '90s
18. Multiple opioid receptors: Ligand selectivity profiles and binding site signatures
19. κ-opioid receptors also increase potassium conductance
20. Dynorphin A (1-13) neurotoxicity in vitro: Opioid and non-opioid mechanisms in mouse spinal cord neurons
21. Putative κ-2 opioid agonists are antihyperalgesic in a rat model of inflammation
22. Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development
23. Intrathecal morphine in mice: A new technique
24. Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: Stimulus specificity, behavioral parameters and opioid receptor binding
25. Clonidine potentiates the neuropathic pain-relieving action of MK-801 while preventing its neurotoxic and hyperactivity side effects
26. Pro-apoptotic function of calsenilin/DREAM/KChIP3
27. Dynorphin increases in the dorsal spinal cord in rats with a painful peripheral neuropathy
28. Dynorphin uses a non-opioid mechanism to potentiate N-methyl-D-aspartate currents in single rat periaqueductal gray neurons
29. Spinally administered dynorphin A produces long-lasting allodynia: Involvement of NMDA but not opioid receptors
30. Mechanisms of induction of persistent nociception by dynorphin
31. Molecular mechanisms of pain: Serotonin1A receptor agonists trigger transactivation by c-fos of the prodynorphin gene in spinal cord neurons
32. Antinociceptive effects of NMDA and non-NMDA receptor antagonists in the tail flick test in mice
33. Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats
34. Anatomy of CNS opioid receptors
35. Cannabinoid modulation of dynorphin A: Correlation to cannabinoid-induced antinociception
36. Basal and inducible transcriptional activity of an upstream AP-1/CRE element (DYNCRE3) in the prodynorphin promoter
37. Fixed-diameter polyethylene cuffs applied to the rat sciatic nerve induce a painful neuropathy: Ultrastructural morphometric analysis of axonal alterations
38. +-currents
39. Dynorphin exerts both postsynaptic and presynaptic effects in the Globus pallidus of the rat
40. Nerve constriction in the rat: Model of neuropathic, surgical and central pain
41. κ-opioid receptor agonists modulate excitatory transmission in substantia gelatinosa neurons of the rat spinal cord
42. 2+ currents and secretion in isolated neuroendocrine nerve terminals
43. Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue
44. Generation of dynorphin knockout mice
45. Mouse dream/calsenilin/kchip3: Gene structure, coding potential, and expression
46. The effectiveness of spinal and systemic morphine on rat dorsal horn neuronal responses in the spinal nerve ligation model of neuropathic pain
47. High-affinity interaction of (des-Tyrosyl)dynorphin A(2-17) with NMDA receptors
48. Inhibition of dynorphin-converting enzymes prolongs the antinociceptive effect of intrathecally administered dynorphin in the mouse formalin test
49. Endogenous opiates: 1999
50. Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: Blockade by MK-801 but not naloxone
51. 2+-binding protein
52. Pronociceptive actions of dynorphin maintain chronic neuropathic pain
53. Analysis of behavior in laboratory rodents
54. Targeted expression of a dominant-negative K(v)4.2 K(+) channel subunit in the mouse heart
55. Dynorphin A-mediated reduction in multiple calcium currents involves a G(o) alpha-subtype G protein in rat primary afferent neurons
56. Neuropathic pain: Aetiology, symptoms, mechanisms, and management
57. Neuronal plasticity: Increasing the gain in pain
58. Dynorphin-(1-8) inhibits the release of substance P-like immunoreactivity in the spinal cord of rats following a noxious mechanical stimulus