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Volumn 116, Issue 3, 2003, Pages 807-816

Dynorphin A toxicity in striatal neurons via an α-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor mechanism

Author keywords

Ampakine; Dizocilpine; N methyl D aspartate receptor complex; Neuroprotection; Neurotoxicology; Striatal neurons; amino 3 hydroxy 5 methylisoxazole 4 propionate receptor complex; opioid receptors

Indexed keywords

1 (1,4 BENZODIOXAN 6 YLCARBONYL)PIPERIDINE; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR; DIZOCILPINE; DYNORPHIN A; GLUTAMIC ACID; KAINIC ACID RECEPTOR; KAPPA OPIATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NALOXONE; PIPERIDINE DERIVATIVE; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

EID: 0037450495     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00563-8     Document Type: Article
Times cited : (18)

References (55)
  • 1
    • 0030436860 scopus 로고    scopus 로고
    • Effects of a memory-enhancing drug on DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor currents and synaptic transmission in hippocampus
    • Arai A., Kessler M., Rogers G., Lynch G. Effects of a memory-enhancing drug on DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor currents and synaptic transmission in hippocampus. J Pharmacol Exp Ther. 278:1996;627-638.
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 627-638
    • Arai, A.1    Kessler, M.2    Rogers, G.3    Lynch, G.4
  • 2
    • 0031581056 scopus 로고    scopus 로고
    • AMPA/kainate receptors modulate the survival in vitro of embryonic brainstem cells
    • Bardoul M., Drian M.J., Konig N. AMPA/kainate receptors modulate the survival in vitro of embryonic brainstem cells. Int J Dev Neurosci. 15:1997;695-701.
    • (1997) Int J Dev Neurosci , vol.15 , pp. 695-701
    • Bardoul, M.1    Drian, M.J.2    Konig, N.3
  • 3
    • 0032934832 scopus 로고    scopus 로고
    • Dynorphin A processing enzyme: Tissue distribution, isolation, and characterization
    • Berman Y., Ageyeva L., Veksler B., Wood D., Devi L.A. Dynorphin A processing enzyme tissue distribution, isolation, and characterization. J Biochem (Tokyo). 125:1999;641-647.
    • (1999) J Biochem (Tokyo) , vol.125 , pp. 641-647
    • Berman, Y.1    Ageyeva, L.2    Veksler, B.3    Wood, D.4    Devi, L.A.5
  • 5
    • 0033954722 scopus 로고    scopus 로고
    • Mitogenic signaling via endogenous kappa-opioid receptors in C6 glioma cells: Evidence for the involvement of protein kinase C and the mitogen-activated protein kinase signaling cascade
    • Bohn L.M., Belcheva M.M., Coscia C.J. Mitogenic signaling via endogenous kappa-opioid receptors in C6 glioma cells evidence for the involvement of protein kinase C and the mitogen-activated protein kinase signaling cascade. J Neurochem. 74:2000;564-573.
    • (2000) J Neurochem , vol.74 , pp. 564-573
    • Bohn, L.M.1    Belcheva, M.M.2    Coscia, C.J.3
  • 6
    • 0033232538 scopus 로고    scopus 로고
    • Ca(2+) permeation of AMPA receptors in cerebellar neurons expressing glu receptor 2
    • Brorson J.R., Zhang Z., Vandenberghe W. Ca(2+) permeation of AMPA receptors in cerebellar neurons expressing glu receptor 2. J Neurosci. 19:1999;9149-9159.
    • (1999) J Neurosci , vol.19 , pp. 9149-9159
    • Brorson, J.R.1    Zhang, Z.2    Vandenberghe, W.3
  • 7
    • 0031971454 scopus 로고    scopus 로고
    • Ifenprodil blocks the excitatory effects of the opioid peptide dynorphin 1-17 on NMDA receptor-mediated currents in the CA3 region of the guinea pig hippocampus
    • Caudle R.M., Dubner R. Ifenprodil blocks the excitatory effects of the opioid peptide dynorphin 1-17 on NMDA receptor-mediated currents in the CA3 region of the guinea pig hippocampus. Neuropeptides. 32:1998;87-95.
    • (1998) Neuropeptides , vol.32 , pp. 87-95
    • Caudle, R.M.1    Dubner, R.2
  • 8
    • 0023854756 scopus 로고
    • A novel interaction between dynorphin(1-13) and an N-methyl-D-aspartate site
    • Caudle R.M., Isaac L. A novel interaction between dynorphin(1-13) and an N-methyl-D-aspartate site. Brain Res. 443:1988;329-332.
    • (1988) Brain Res , vol.443 , pp. 329-332
    • Caudle, R.M.1    Isaac, L.2
  • 9
    • 0034253821 scopus 로고    scopus 로고
    • Dynorphin: Friend or foe?
    • Caudle R.M., Mannes A.J. Dynorphin friend or foe? Pain. 87:2000;235-239.
    • (2000) Pain , vol.87 , pp. 235-239
    • Caudle, R.M.1    Mannes, A.J.2
  • 10
    • 0029005428 scopus 로고
    • The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphin
    • Chen L., Gu Y., Huang L.Y. The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphin. J Neurosci. 15:1995;4602-4611.
    • (1995) J Neurosci , vol.15 , pp. 4602-4611
    • Chen, L.1    Gu, Y.2    Huang, L.Y.3
  • 11
    • 0028949109 scopus 로고
    • The opioid peptide dynorphin directly blocks NMDA receptor channels in the rat
    • Chen L., Gu Y., Huang L.Y. The opioid peptide dynorphin directly blocks NMDA receptor channels in the rat. J Physiol. 482:1995;575-581.
    • (1995) J Physiol , vol.482 , pp. 575-581
    • Chen, L.1    Gu, Y.2    Huang, L.Y.3
  • 12
    • 0026552808 scopus 로고
    • Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation
    • Chen L., Huang L.Y. Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation. Nature. 356:1992;521-523.
    • (1992) Nature , vol.356 , pp. 521-523
    • Chen, L.1    Huang, L.Y.2
  • 13
    • 0028884653 scopus 로고
    • Glutamate-mediated excitotoxic death of cultured striatal neurons is mediated by non-NMDA receptors
    • Chen Q., Harris C., Brown C.S., Howe A., Surmeier D.J., Reiner A. Glutamate-mediated excitotoxic death of cultured striatal neurons is mediated by non-NMDA receptors. Exp Neurol. 136:1995;212-224.
    • (1995) Exp Neurol , vol.136 , pp. 212-224
    • Chen, Q.1    Harris, C.2    Brown, C.S.3    Howe, A.4    Surmeier, D.J.5    Reiner, A.6
  • 15
    • 0031985151 scopus 로고    scopus 로고
    • Prodynorphin processing by proprotein convertase 2. Cleavage at single basic residues and enhanced processing in the presence of carboxypeptidase activity
    • Day R., Lazure C., Basak A., Boudreault A., Limperis P., Dong W., Lindberg I. Prodynorphin processing by proprotein convertase 2. Cleavage at single basic residues and enhanced processing in the presence of carboxypeptidase activity. J Biol Chem. 273:1998;829-836.
    • (1998) J Biol Chem , vol.273 , pp. 829-836
    • Day, R.1    Lazure, C.2    Basak, A.3    Boudreault, A.4    Limperis, P.5    Dong, W.6    Lindberg, I.7
  • 16
    • 0035102603 scopus 로고    scopus 로고
    • Blockade of AMPA/kainate receptors can either decrease or increase the survival of cultured neocortical cells depending on the stage of maturation
    • Drian M., Bardoul M., Konig N. Blockade of AMPA/kainate receptors can either decrease or increase the survival of cultured neocortical cells depending on the stage of maturation. Neurochem Int. 38:2001;509-517.
    • (2001) Neurochem Int , vol.38 , pp. 509-517
    • Drian, M.1    Bardoul, M.2    Konig, N.3
  • 17
    • 0026500432 scopus 로고
    • Activity-dependent neuronal plasticity following tissue injury and inflammation
    • Dubner R., Ruda M.A. Activity-dependent neuronal plasticity following tissue injury and inflammation. Trends Neurosci. 15:1992;96-103.
    • (1992) Trends Neurosci , vol.15 , pp. 96-103
    • Dubner, R.1    Ruda, M.A.2
  • 18
    • 0027884838 scopus 로고
    • Experimental neurobiology of central nervous system trauma
    • Faden A.I. Experimental neurobiology of central nervous system trauma. Crit Rev Neurobiol. 7:1993;175-186.
    • (1993) Crit Rev Neurobiol , vol.7 , pp. 175-186
    • Faden, A.I.1
  • 19
    • 0026540898 scopus 로고
    • Pharmacological strategies in CNS trauma
    • Faden A.I., Salzman S. Pharmacological strategies in CNS trauma. Trends Pharmacol Sci. 13:1992;29-35.
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 29-35
    • Faden, A.I.1    Salzman, S.2
  • 20
    • 0026763483 scopus 로고
    • Kappa opioid agonists inhibit transmitter release from guinea pig hippocampal mossy fiber synaptosomes
    • Gannon R.L., Terrian D.M. Kappa opioid agonists inhibit transmitter release from guinea pig hippocampal mossy fiber synaptosomes. Neurochem Res. 17:1992;741-747.
    • (1992) Neurochem Res , vol.17 , pp. 741-747
    • Gannon, R.L.1    Terrian, D.M.2
  • 21
    • 0028917372 scopus 로고
    • Nitric oxide signaling in the central nervous system
    • Garthwaite J., Boulton C.L. Nitric oxide signaling in the central nervous system. Ann Rev Physiol. 57:1995;683-706.
    • (1995) Ann Rev Physiol , vol.57 , pp. 683-706
    • Garthwaite, J.1    Boulton, C.L.2
  • 22
    • 0021381221 scopus 로고
    • Dynorphin: Potent analgesic effect in spinal cord of the rat
    • Han J.S., Xie C.W. Dynorphin potent analgesic effect in spinal cord of the rat. Sci Sin [B]. 27:1984;169-177.
    • (1984) Sci Sin [B] , vol.27 , pp. 169-177
    • Han, J.S.1    Xie, C.W.2
  • 23
    • 0032786125 scopus 로고    scopus 로고
    • Dynorphin A (1-13) neurotoxicity in vitro: Opioid and non-opioid mechanisms in mouse spinal cord neurons
    • Hauser K.F., Foldes J.K., Turbek C.S. Dynorphin A (1-13) neurotoxicity in vitro opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 160:1999;361-375.
    • (1999) Exp Neurol , vol.160 , pp. 361-375
    • Hauser, K.F.1    Foldes, J.K.2    Turbek, C.S.3
  • 24
    • 0035120270 scopus 로고    scopus 로고
    • Structure-activity analysis of dynorphin A toxicity in spinal cord neurons: Intrinsic neurotoxicity of dynorphin A and its carboxyl-terminal, nonopioid metabolites
    • Hauser K.F., Knapp P.E., Turbek C.S. Structure-activity analysis of dynorphin A toxicity in spinal cord neurons intrinsic neurotoxicity of dynorphin A and its carboxyl-terminal, nonopioid metabolites. Exp Neurol. 168:2001;78-87.
    • (2001) Exp Neurol , vol.168 , pp. 78-87
    • Hauser, K.F.1    Knapp, P.E.2    Turbek, C.S.3
  • 25
    • 0024550983 scopus 로고
    • Androgen increases the number of cells in fetal mouse spinal cord cultures: Implications for motoneuron survival
    • Hauser K.F., Toran-Allerand C.D. Androgen increases the number of cells in fetal mouse spinal cord cultures implications for motoneuron survival. Brain Res. 485:1989;157-164.
    • (1989) Brain Res , vol.485 , pp. 157-164
    • Hauser, K.F.1    Toran-Allerand, C.D.2
  • 26
    • 0021952580 scopus 로고
    • Antinociception and paralysis induced by intrathecal dynorphine A
    • Herman B.H., Goldstein A. Antinociception and paralysis induced by intrathecal dynorphine A. J Pharmacol Exp Ther. 232:1985;27-32.
    • (1985) J Pharmacol Exp Ther , vol.232 , pp. 27-32
    • Herman, B.H.1    Goldstein, A.2
  • 27
    • 0030040450 scopus 로고    scopus 로고
    • Dynorphin neurotoxicity induced nitric oxide synthase expression in ventral horn cells of rat spinal cord
    • Hu W.H., Lee F.C., Wan X.S., Chen Y.T., Jen M.F. Dynorphin neurotoxicity induced nitric oxide synthase expression in ventral horn cells of rat spinal cord. Neurosci Lett. 203:1996;13-16.
    • (1996) Neurosci Lett , vol.203 , pp. 13-16
    • Hu, W.H.1    Lee, F.C.2    Wan, X.S.3    Chen, Y.T.4    Jen, M.F.5
  • 29
    • 0035424106 scopus 로고    scopus 로고
    • Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons
    • Jensen J.B., Lund T.M., Timmermann D.B., Schousboe A., Pickering D.S. Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons. J Neurosci Res. 65:2001;267-277.
    • (2001) J Neurosci Res , vol.65 , pp. 267-277
    • Jensen, J.B.1    Lund, T.M.2    Timmermann, D.B.3    Schousboe, A.4    Pickering, D.S.5
  • 30
    • 0035313417 scopus 로고    scopus 로고
    • Protective effects of morphine in peroxynitrite-induced apoptosis of primary rat neonatal astrocytes: Potential involvement of G protein and phosphatidylinositol 3-kinase (PI3 kinase)
    • Kim M.S., Cheong Y.P., So H.S., Lee K.M., Kim T.Y., Oh J., Chung Y.T., Son Y., Kim B.R., Park R. Protective effects of morphine in peroxynitrite-induced apoptosis of primary rat neonatal astrocytes potential involvement of G protein and phosphatidylinositol 3-kinase (PI3 kinase). Biochem Pharmacol. 61:2001;779-786.
    • (2001) Biochem Pharmacol , vol.61 , pp. 779-786
    • Kim, M.S.1    Cheong, Y.P.2    So, H.S.3    Lee, K.M.4    Kim, T.Y.5    Oh, J.6    Chung, Y.T.7    Son, Y.8    Kim, B.R.9    Park, R.10
  • 31
    • 0028861259 scopus 로고
    • The opioid peptide dynorphin modulates AMPA and kainate responses in acutely isolated neurons from the dorsal horn
    • Kolaj M., Cerne R., Randic M. The opioid peptide dynorphin modulates AMPA and kainate responses in acutely isolated neurons from the dorsal horn. Brain Res. 671:1995;227-244.
    • (1995) Brain Res , vol.671 , pp. 227-244
    • Kolaj, M.1    Cerne, R.2    Randic, M.3
  • 32
    • 0035123249 scopus 로고    scopus 로고
    • Cortical and striatal neuronal cultures of the same embryonic origin show intrinsic differences in glutamate receptor expression and vulnerability to excitotoxicity
    • Kovacs A.D., Cebers G., Cebere A., Moreira T., Liljequist S. Cortical and striatal neuronal cultures of the same embryonic origin show intrinsic differences in glutamate receptor expression and vulnerability to excitotoxicity. Exp Neurol. 168:2001;47-62.
    • (2001) Exp Neurol , vol.168 , pp. 47-62
    • Kovacs, A.D.1    Cebers, G.2    Cebere, A.3    Moreira, T.4    Liljequist, S.5
  • 33
    • 0030879183 scopus 로고    scopus 로고
    • Spinally administered dynorphin A produces long-lasting allodynia: Involvement of NMDA but not opioid receptors
    • Laughlin T.M., Vanderah T.W., Lashbrook J., Nichols M.L., Ossipov M., Porreca F., Wilcox G.L. Spinally administered dynorphin A produces long-lasting allodynia involvement of NMDA but not opioid receptors. Pain. 72:1997;253-260.
    • (1997) Pain , vol.72 , pp. 253-260
    • Laughlin, T.M.1    Vanderah, T.W.2    Lashbrook, J.3    Nichols, M.L.4    Ossipov, M.5    Porreca, F.6    Wilcox, G.L.7
  • 34
    • 0028344182 scopus 로고
    • Dynorphin A-induced rat spinal cord injury: Evidence for excitatory amino acid involvement in a pharmacological model of ischemic spinal cord injury
    • Long J.B., Rigamonti D.D., Oleshansky M.A., Wingfield C.P., Martinez-Arizala A. Dynorphin A-induced rat spinal cord injury evidence for excitatory amino acid involvement in a pharmacological model of ischemic spinal cord injury. J Pharmacol Exp Ther. 269:1994;358-366.
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 358-366
    • Long, J.B.1    Rigamonti, D.D.2    Oleshansky, M.A.3    Wingfield, C.P.4    Martinez-Arizala, A.5
  • 35
    • 0026721863 scopus 로고
    • Cholinergic and opioid mediation of traumatic brain injury
    • Lyeth B.G., Hayes R.L. Cholinergic and opioid mediation of traumatic brain injury. J Neurotrauma. 9:1992;S463-474.
    • (1992) J Neurotrauma , vol.9 , pp. 463-474
    • Lyeth, B.G.1    Hayes, R.L.2
  • 36
    • 0032484534 scopus 로고    scopus 로고
    • AMPA receptor protein in developing rat brain: Glutamate receptor-1 expression and localization change at regional, cellular, and subcellular levels with maturation
    • Martin L.J., Furuta A., Blackstone C.D. AMPA receptor protein in developing rat brain glutamate receptor-1 expression and localization change at regional, cellular, and subcellular levels with maturation. Neuroscience. 83:1998;917-928.
    • (1998) Neuroscience , vol.83 , pp. 917-928
    • Martin, L.J.1    Furuta, A.2    Blackstone, C.D.3
  • 37
    • 0029175202 scopus 로고
    • Calcium, free radicals, and excitotoxic neuronal death in primary cell culture
    • Mattson M.P., Barger S.W., Begley J.G., Mark R.J. Calcium, free radicals, and excitotoxic neuronal death in primary cell culture. Methods Cell Biol. 46:1995;187-216.
    • (1995) Methods Cell Biol , vol.46 , pp. 187-216
    • Mattson, M.P.1    Barger, S.W.2    Begley, J.G.3    Mark, R.J.4
  • 38
    • 0028041046 scopus 로고
    • Central and systemic kappa-opioid agonists exacerbate neurobehavioral response to brain injury in rats
    • McIntosh T.K., Fernyak S., Yamakami I., Faden A.I. Central and systemic kappa-opioid agonists exacerbate neurobehavioral response to brain injury in rats. Am J Physiol. 267:1994;R665-672.
    • (1994) Am J Physiol , vol.267 , pp. 665-672
    • McIntosh, T.K.1    Fernyak, S.2    Yamakami, I.3    Faden, A.I.4
  • 39
    • 0023553426 scopus 로고
    • Alterations in regional concentrations of endogenous opioids following traumatic brain injury in the cat
    • McIntosh T.K., Head V.A., Faden A.I. Alterations in regional concentrations of endogenous opioids following traumatic brain injury in the cat. Brain Res. 425:1987;225-233.
    • (1987) Brain Res , vol.425 , pp. 225-233
    • McIntosh, T.K.1    Head, V.A.2    Faden, A.I.3
  • 40
    • 0032737064 scopus 로고    scopus 로고
    • Role of cyclic GMP in glutamate neurotoxicity in primary cultures of cerebellar neurons
    • Montoliu C., Llansola M., Kosenko E., Corbalan R., Felipo V. Role of cyclic GMP in glutamate neurotoxicity in primary cultures of cerebellar neurons. Neuropharmacology. 38:1999;1883-1891.
    • (1999) Neuropharmacology , vol.38 , pp. 1883-1891
    • Montoliu, C.1    Llansola, M.2    Kosenko, E.3    Corbalan, R.4    Felipo, V.5
  • 41
    • 0034793047 scopus 로고    scopus 로고
    • Mechanism and impact of allosteric AMPA receptor modulation by the ampakine CX546
    • Nagarajan N., Quast C., Boxall A.R., Shahid M., Rosenmund C. Mechanism and impact of allosteric AMPA receptor modulation by the ampakine CX546. Neuropharmacology. 41:2001;650-663.
    • (2001) Neuropharmacology , vol.41 , pp. 650-663
    • Nagarajan, N.1    Quast, C.2    Boxall, A.R.3    Shahid, M.4    Rosenmund, C.5
  • 42
    • 0021951669 scopus 로고
    • Analgesic effects of dynorphin-A and morphine in mice
    • Nakazawa T., Ikeda M., Kaneko T., Yamatsu K. Analgesic effects of dynorphin-A and morphine in mice. Peptides. 6:1985;75-78.
    • (1985) Peptides , vol.6 , pp. 75-78
    • Nakazawa, T.1    Ikeda, M.2    Kaneko, T.3    Yamatsu, K.4
  • 44
    • 0032483540 scopus 로고    scopus 로고
    • Mu-Opioid receptor activates signaling pathways implicated in cell survival and translational control
    • Polakiewicz R.D., Schieferl S.M., Gingras A.C., Sonenberg N., Comb M.J. mu-Opioid receptor activates signaling pathways implicated in cell survival and translational control. J Biol Chem. 273:1998;23534-23541.
    • (1998) J Biol Chem , vol.273 , pp. 23534-23541
    • Polakiewicz, R.D.1    Schieferl, S.M.2    Gingras, A.C.3    Sonenberg, N.4    Comb, M.J.5
  • 45
    • 0020643094 scopus 로고
    • Studies in vivo with dynorphin-(1-9): Analgesia but not gastrointestinal effects following intrathecal administration to mice
    • Porreca F., Filla A., Burks T.F. Studies in vivo with dynorphin-(1-9) analgesia but not gastrointestinal effects following intrathecal administration to mice. Eur J Pharmacol. 91:1983;291-294.
    • (1983) Eur J Pharmacol , vol.91 , pp. 291-294
    • Porreca, F.1    Filla, A.2    Burks, T.F.3
  • 46
    • 0026986667 scopus 로고
    • Central non-opioid physiological and pathophysiological effects of dynorphin A and related peptides
    • Shukla V.K., Lemaire S. Central non-opioid physiological and pathophysiological effects of dynorphin A and related peptides. J Psychiatry Neurosci. 17:1992;106-119.
    • (1992) J Psychiatry Neurosci , vol.17 , pp. 106-119
    • Shukla, V.K.1    Lemaire, S.2
  • 47
    • 0028080298 scopus 로고
    • Non-opioid effects of dynorphins: Possible role of the NMDA receptor
    • Shukla V.K., Lemaire S. Non-opioid effects of dynorphins possible role of the NMDA receptor. Trends Pharmacol Sci. 15:1994;420-424.
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 420-424
    • Shukla, V.K.1    Lemaire, S.2
  • 48
    • 0032077679 scopus 로고    scopus 로고
    • Nitric oxide and carbon monoxide: Parallel roles as neural messengers
    • Snyder S.H., Jaffrey S.R., Zakhary R. Nitric oxide and carbon monoxide parallel roles as neural messengers. Brain Res Rev. 26:1998;167-175.
    • (1998) Brain Res Rev , vol.26 , pp. 167-175
    • Snyder, S.H.1    Jaffrey, S.R.2    Zakhary, R.3
  • 49
    • 0021992303 scopus 로고
    • Characterization of dynorphin A-induced antinociception at spinal level
    • Spampinato S., Candeletti S. Characterization of dynorphin A-induced antinociception at spinal level. Eur J Pharmacol. 110:1985;21-30.
    • (1985) Eur J Pharmacol , vol.110 , pp. 21-30
    • Spampinato, S.1    Candeletti, S.2
  • 51
    • 0034128003 scopus 로고    scopus 로고
    • Dynorphin A elicits an increase in intracellular calcium in cultured neurons via a non-opioid, non-NMDA mechanism
    • Tang Q., Lynch R.M., Porreca F., Lai J. Dynorphin A elicits an increase in intracellular calcium in cultured neurons via a non-opioid, non-NMDA mechanism. J Neurophysiol. 83:2000;2610-2615.
    • (2000) J Neurophysiol , vol.83 , pp. 2610-2615
    • Tang, Q.1    Lynch, R.M.2    Porreca, F.3    Lai, J.4
  • 53
    • 17344385566 scopus 로고    scopus 로고
    • Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: Blockade by MK-801 but not naloxone
    • Vanderah T.W., Laughlin T., Lashbrook J.M., Nichols M.L., Wilcox G.L., Ossipov M.H., Malan T.P. Jr, Porreca F. Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats blockade by MK-801 but not naloxone. Pain. 68:1996;275-281.
    • (1996) Pain , vol.68 , pp. 275-281
    • Vanderah, T.W.1    Laughlin, T.2    Lashbrook, J.M.3    Nichols, M.L.4    Wilcox, G.L.5    Ossipov, M.H.6    Malan, T.P.7    Porreca, F.8
  • 54
    • 0029293997 scopus 로고
    • Comparative study of the analgesic and paralytic effects induced by intrathecal dynorphin a in rats
    • Xue J.C., Yu Y.X., Han J.S., Jen M.F. Comparative study of the analgesic and paralytic effects induced by intrathecal dynorphin a in rats. Int J Neurosci. 82:1995;83-93.
    • (1995) Int J Neurosci , vol.82 , pp. 83-93
    • Xue, J.C.1    Yu, Y.X.2    Han, J.S.3    Jen, M.F.4
  • 55
    • 0028124241 scopus 로고
    • The developmental expression in rat of proteases furin, PC1, PC2, and carboxypeptidase E: Implications for early maturation of proteolytic processing capacity
    • Zheng M., Streck R.D., Scott R.E., Seidah N.G., Pintar J.E. The developmental expression in rat of proteases furin, PC1, PC2, and carboxypeptidase E implications for early maturation of proteolytic processing capacity. J Neurosci. 14:1994;4656-4673.
    • (1994) J Neurosci , vol.14 , pp. 4656-4673
    • Zheng, M.1    Streck, R.D.2    Scott, R.E.3    Seidah, N.G.4    Pintar, J.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.