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Volumn 70, Issue 5, 1998, Pages 1809-1818

A DEVD-inhibited caspase other than CPP32 is involved in the commitment of cerebellar granule neurons to apoptosis induced by K+ deprivation

Author keywords

Benzyloxycarbonyl Val Ala Asp fluoromethyl ketone; CPP32; Nedd2; Neuronal survival; Poly(ADP ridose)polymerase; Tert Butoxycarbonyl Asp (O methyl) fluoromethyl ketone

Indexed keywords

BENZYLOXYCARBONYLPHENYLALANYLALANYL FLUOROMETHYL KETONE;

EID: 0031958511     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70051809.x     Document Type: Article
Times cited : (68)

References (54)
  • 1
    • 0031044652 scopus 로고    scopus 로고
    • Mammalian cell death proteases: A family of highly conserved aspartate specific cysteine proteases
    • Alnemri E. S. (1997) Mammalian cell death proteases: a family of highly conserved aspartate specific cysteine proteases. J. Cell. Biochem. 64, 33-42.
    • (1997) J. Cell. Biochem. , vol.64 , pp. 33-42
    • Alnemri, E.S.1
  • 3
    • 0029614765 scopus 로고
    • Neural apoptosis
    • Bredesen D. E. (1995) Neural apoptosis. Ann. Neurol. 38, 839-851.
    • (1995) Ann. Neurol. , vol.38 , pp. 839-851
    • Bredesen, D.E.1
  • 5
    • 0023896376 scopus 로고
    • Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones
    • Cull-Candy S. G., Howe J. R., and Ogden D. C. (1988) Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones. J. Physiol. (Lond.) 400, 189-222.
    • (1988) J. Physiol. (Lond.) , vol.400 , pp. 189-222
    • Cull-Candy, S.G.1    Howe, J.R.2    Ogden, D.C.3
  • 6
    • 0030995802 scopus 로고    scopus 로고
    • Programmed cell death in neurons: Focus on the pathway of nerve growth factor-induced death of sympathetic neurons
    • Deshmukh M. and Johnson E. M. Jr. (1997) Programmed cell death in neurons: focus on the pathway of nerve growth factor-induced death of sympathetic neurons. Mol. Pharmacol. 51, 897-906.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 897-906
    • Deshmukh, M.1    Johnson Jr., E.M.2
  • 7
    • 0030458720 scopus 로고    scopus 로고
    • Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases
    • Deshmukh M., Vasilakos J., Deckwerth T. L., Lampe P. A., Shrivers B. D., and Johnson E. M. Jr. (1996) Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases. J. Cell Biol. 135, 1341-1354.
    • (1996) J. Cell Biol. , vol.135 , pp. 1341-1354
    • Deshmukh, M.1    Vasilakos, J.2    Deckwerth, T.L.3    Lampe, P.A.4    Shrivers, B.D.5    Johnson Jr., E.M.6
  • 8
    • 0027483920 scopus 로고
    • Induction of apoptosis in cerebellar granule neurons by lowering of extracellular potassium: Inhibition of death by IGF-I and cAMP
    • D'Mello S. R., Galli C., Ciotti T., and Calissano P. (1993) Induction of apoptosis in cerebellar granule neurons by lowering of extracellular potassium: inhibition of death by IGF-I and cAMP. Proc. Natl. Acad. Sci. USA 90, 10989-10993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10989-10993
    • D'Mello, S.R.1    Galli, C.2    Ciotti, T.3    Calissano, P.4
  • 10
    • 0029853389 scopus 로고    scopus 로고
    • Pivotal role of a DEVD-sensitive step in etoposide-induced and Fas-mediated apoptotic pathways
    • Dubrez L., Savoy I., Hamman A., and Solary E. (1996) Pivotal role of a DEVD-sensitive step in etoposide-induced and Fas-mediated apoptotic pathways. EMBO J. 15, 5504-5512.
    • (1996) EMBO J. , vol.15 , pp. 5504-5512
    • Dubrez, L.1    Savoy, I.2    Hamman, A.3    Solary, E.4
  • 11
    • 0031055018 scopus 로고    scopus 로고
    • Characterization of anti-peptide antibodies directed towards the automodification domain and apoptotic fragment of poly(ADP-ribose) polymerase
    • Duriez P. J., Desnoyers S., Hoflack J.-C., Shah G. M., Morelle B., Bourassa S., Poirier G. G., and Talbot B. (1997) Characterization of anti-peptide antibodies directed towards the automodification domain and apoptotic fragment of poly(ADP-ribose) polymerase. Biochim. Biophys. Acta 1334, 65-72.
    • (1997) Biochim. Biophys. Acta , vol.1334 , pp. 65-72
    • Duriez, P.J.1    Desnoyers, S.2    Hoflack, J.-C.3    Shah, G.M.4    Morelle, B.5    Bourassa, S.6    Poirier, G.G.7    Talbot, B.8
  • 12
    • 0030804678 scopus 로고    scopus 로고
    • The role of ced-3-related cysteine proteases in apoptosis of cerebellar granule cells
    • Eldadah B. A., Yakolev A. G., and Faden A. I. (1997) The role of ced-3-related cysteine proteases in apoptosis of cerebellar granule cells. J. Neurosci. 17, 6105-6113.
    • (1997) J. Neurosci. , vol.17 , pp. 6105-6113
    • Eldadah, B.A.1    Yakolev, A.G.2    Faden, A.I.3
  • 13
    • 0029745387 scopus 로고    scopus 로고
    • Involvement of P53 in DNA strand break-induced apoptosis in postmitotic CNS neurons
    • Enokido Y., Araki T., Tanaka K., Aizawa S., and Hatanaka H. (1996) Involvement of P53 in DNA strand break-induced apoptosis in postmitotic CNS neurons. Eur. J. Neurosci. 8, 1812-1821.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1812-1821
    • Enokido, Y.1    Araki, T.2    Tanaka, K.3    Aizawa, S.4    Hatanaka, H.5
  • 14
    • 0029894283 scopus 로고    scopus 로고
    • Activation of CPP32 apoptotic protease by distinct signaling pathways with differential sensitivity to Bcl-XL
    • Erhardt P. and Cooper G. M. (1996) Activation of CPP32 apoptotic protease by distinct signaling pathways with differential sensitivity to Bcl-XL. J. Biol. Chem. 271, 17601-17604.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17601-17604
    • Erhardt, P.1    Cooper, G.M.2
  • 15
    • 0028924891 scopus 로고
    • Apoptosis in cerebellar granule neurons is blocked by high KCl, forskolin, and IGF-I through distinct mechanisms of action: The involvement of intracellular calcium and RNA synthesis
    • Galli C., Meucci O., Scorziello A., Werge T. M., Calissano P., and Schettini G. (1995) Apoptosis in cerebellar granule neurons is blocked by high KCl, forskolin, and IGF-I through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. J. Neurosci. 15, 1172-1179.
    • (1995) J. Neurosci. , vol.15 , pp. 1172-1179
    • Galli, C.1    Meucci, O.2    Scorziello, A.3    Werge, T.M.4    Calissano, P.5    Schettini, G.6
  • 16
    • 0023244774 scopus 로고
    • The role of depolarization in the survival and differentiation of cerebellar granule cells in culture
    • Gallo V., Kingsbury A., Balázs R., and Jorgensen O. S. (1987) The role of depolarization in the survival and differentiation of cerebellar granule cells in culture. J. Neurosci. 7, 2203-2213.
    • (1987) J. Neurosci. , vol.7 , pp. 2203-2213
    • Gallo, V.1    Kingsbury, A.2    Balázs, R.3    Jorgensen, O.S.4
  • 17
    • 0027464867 scopus 로고
    • Polyvinylpyrrolidine as a blocking agent in immunocytochemical studies
    • Haycock J. W. (1993) Polyvinylpyrrolidine as a blocking agent in immunocytochemical studies. Anal. Biochem. 208, 397-399.
    • (1993) Anal. Biochem. , vol.208 , pp. 397-399
    • Haycock, J.W.1
  • 18
    • 0023337650 scopus 로고
    • Immunocytochemical and electrophysiological differentiation of rat cerebellar granule cells in explant cultures
    • Hockberger P. E., Tseng H. Y., and Connor J. A. (1987) Immunocytochemical and electrophysiological differentiation of rat cerebellar granule cells in explant cultures. J. Neurosci. 7, 1370-1383.
    • (1987) J. Neurosci. , vol.7 , pp. 1370-1383
    • Hockberger, P.E.1    Tseng, H.Y.2    Connor, J.A.3
  • 19
    • 0027396983 scopus 로고
    • Molecular mechanisms of developmental neuronal death
    • Johnson E. M. and Deckwerth T. L. (1993) Molecular mechanisms of developmental neuronal death. Annu. Rev. Neurosci. 16, 31-46.
    • (1993) Annu. Rev. Neurosci. , vol.16 , pp. 31-46
    • Johnson, E.M.1    Deckwerth, T.L.2
  • 20
    • 0021925444 scopus 로고
    • An improved method to determine cell viability by simultaneous staining with fluorescein diacetate and propidium iodide
    • Jones K. H. and Senft J. A. (1985) An improved method to determine cell viability by simultaneous staining with fluorescein diacetate and propidium iodide. J. Histochem. Cytochem. 33, 77-79.
    • (1985) J. Histochem. Cytochem. , vol.33 , pp. 77-79
    • Jones, K.H.1    Senft, J.A.2
  • 22
    • 0030960657 scopus 로고    scopus 로고
    • Immunohistochemical analysis of in vivo patterns of expression of CPP32 (caspase-3), a cell death protease
    • Krajewska M., Wang H. G., Krajewski S., Zapata J. M., Shabaik A., Gascoyne R., and Reed J. C. (1997) Immunohistochemical analysis of in vivo patterns of expression of CPP32 (caspase-3), a cell death protease. Cancer Res. 57, 1605-1613.
    • (1997) Cancer Res. , vol.57 , pp. 1605-1613
    • Krajewska, M.1    Wang, H.G.2    Krajewski, S.3    Zapata, J.M.4    Shabaik, A.5    Gascoyne, R.6    Reed, J.C.7
  • 23
    • 0028920863 scopus 로고
    • Altered cytokine export and apoptosis in mice deficient in interleukin-1β-converting enzyme
    • Kuida K., Lippke J. A., Ku G., Harding M. W., Livingston D. J., Su M. S., and Flavell R. A. (1995) Altered cytokine export and apoptosis in mice deficient in interleukin-1β-converting enzyme. Science 267, 2000-2002.
    • (1995) Science , vol.267 , pp. 2000-2002
    • Kuida, K.1    Lippke, J.A.2    Ku, G.3    Harding, M.W.4    Livingston, D.J.5    Su, M.S.6    Flavell, R.A.7
  • 25
    • 0029069295 scopus 로고
    • ICE-like proteases in apoptosis
    • Kumar S. (1995) ICE-like proteases in apoptosis. Trends Biochem. Sci. 20, 198-202.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 198-202
    • Kumar, S.1
  • 26
    • 0027990778 scopus 로고
    • Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1β-converting enzyme
    • Kumar S., Kinoshita M., Noda M., Copeland N. G., and Jenkins N. A. (1994) Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1β-converting enzyme. Genes Dev. 8, 1613-1626.
    • (1994) Genes Dev. , vol.8 , pp. 1613-1626
    • Kumar, S.1    Kinoshita, M.2    Noda, M.3    Copeland, N.G.4    Jenkins, N.A.5
  • 27
    • 0015519878 scopus 로고
    • The effect of potassium on neuronal differentiation in cultures of dissociated new born rat cerebellum
    • Lasher R. S. and Zaigon I. S. (1972) The effect of potassium on neuronal differentiation in cultures of dissociated new born rat cerebellum. Brain Res. 41, 428-488.
    • (1972) Brain Res. , vol.41 , pp. 428-488
    • Lasher, R.S.1    Zaigon, I.S.2
  • 28
    • 0021335259 scopus 로고
    • Autoradiographic localization and depolarization-induced release of acidic amino acids in differentiating cerebellar granule cell cultures
    • Levi G., Aloisi F., Ciotti M. T., and Gallo V. (1984) Autoradiographic localization and depolarization-induced release of acidic amino acids in differentiating cerebellar granule cell cultures. Brain Res. 290, 77-86.
    • (1984) Brain Res. , vol.290 , pp. 77-86
    • Levi, G.1    Aloisi, F.2    Ciotti, M.T.3    Gallo, V.4
  • 31
    • 0031044283 scopus 로고    scopus 로고
    • In vitro and in vivo studies of ICE inhibitors
    • Livingston D. J. (1997) In vitro and in vivo studies of ICE inhibitors. J. Cell. Biochem. 64, 19-26.
    • (1997) J. Cell. Biochem. , vol.64 , pp. 19-26
    • Livingston, D.J.1
  • 32
    • 0030959653 scopus 로고    scopus 로고
    • Inhibition of the interleukin-1 beta converting enzyme family rescues neurons from apoptotic death
    • Lynch T., Vasilakos J. P., Raser K., Keane K. M., and Shivers B. D. (1997) Inhibition of the interleukin-1 beta converting enzyme family rescues neurons from apoptotic death. Mol. Psychiatry 2, 227-238.
    • (1997) Mol. Psychiatry , vol.2 , pp. 227-238
    • Lynch, T.1    Vasilakos, J.P.2    Raser, K.3    Keane, K.M.4    Shivers, B.D.5
  • 33
    • 0030897988 scopus 로고    scopus 로고
    • Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases
    • Margolin N., Raybuck S. A., Wilson K. P., Chen W., Fox T., Gu Y., and Livingston D. J. (1997) Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases. J. Biol. Chem. 272, 7223-7228.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7223-7228
    • Margolin, N.1    Raybuck, S.A.2    Wilson, K.P.3    Chen, W.4    Fox, T.5    Gu, Y.6    Livingston, D.J.7
  • 34
    • 0031033274 scopus 로고    scopus 로고
    • Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak
    • McCarthy J. N., Whyte M. K. B., Gilbert C. S., and Evan G. I. (1997) Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak. J. Cell Biol. 136, 215-227.
    • (1997) J. Cell Biol. , vol.136 , pp. 215-227
    • McCarthy, J.N.1    Whyte, M.K.B.2    Gilbert, C.S.3    Evan, G.I.4
  • 35
    • 1842456916 scopus 로고    scopus 로고
    • Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development
    • Michaelidis T. M., Sendtner M., Cooper J. D., Airaksinen M. S., Holtmann B., Meyer M., and Thoenen H. (1996) Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development. Neuron 17, 75-89.
    • (1996) Neuron , vol.17 , pp. 75-89
    • Michaelidis, T.M.1    Sendtner, M.2    Cooper, J.D.3    Airaksinen, M.S.4    Holtmann, B.5    Meyer, M.6    Thoenen, H.7
  • 36
    • 0029909560 scopus 로고    scopus 로고
    • Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule neurons
    • Miller T. M. and Johnson E. M. Jr. (1996) Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule neurons. J. Neurosci. 16, 7487-7495.
    • (1996) J. Neurosci. , vol.16 , pp. 7487-7495
    • Miller, T.M.1    Johnson Jr., E.M.2
  • 37
    • 0030994236 scopus 로고    scopus 로고
    • Evidence for CPP32 activation in the absence of apoptosis during T lymphocyte stimulation
    • Moissec C., Dutilleul V., Fassy F., and Diu-Hercend A. (1997) Evidence for CPP32 activation in the absence of apoptosis during T lymphocyte stimulation. J. Biol. Chem. 272, 13459-13462.
    • (1997) J. Biol. Chem. , vol.272 , pp. 13459-13462
    • Moissec, C.1    Dutilleul, V.2    Fassy, F.3    Diu-Hercend, A.4
  • 38
    • 0031021770 scopus 로고    scopus 로고
    • Biochemical and temporal analysis of events associated with apoptosis induced by lowering the extracellular potassium concentration in mouse cerebellar granule neurons
    • Nardi N., Abidan G., Daily D., Zilkha-Falb R. Z., and Barzilai A. (1997) Biochemical and temporal analysis of events associated with apoptosis induced by lowering the extracellular potassium concentration in mouse cerebellar granule neurons. J. Neurochem. 68, 750-759.
    • (1997) J. Neurochem. , vol.68 , pp. 750-759
    • Nardi, N.1    Abidan, G.2    Daily, D.3    Zilkha-Falb, R.Z.4    Barzilai, A.5
  • 39
    • 0031051502 scopus 로고    scopus 로고
    • Cloning and expression of a rat brain interleukin-1-β-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons
    • Ni B., Wu X., Du Y., Su Y., Hamilton-Byrd E., Rockey P. K., Rosteck P., Poirier G. G., and Paul S. M. (1997) Cloning and expression of a rat brain interleukin-1-β-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons. J. Neurosci. 17, 1561-1569.
    • (1997) J. Neurosci. , vol.17 , pp. 1561-1569
    • Ni, B.1    Wu, X.2    Du, Y.3    Su, Y.4    Hamilton-Byrd, E.5    Rockey, P.K.6    Rosteck, P.7    Poirier, G.G.8    Paul, S.M.9
  • 41
    • 0030788276 scopus 로고    scopus 로고
    • Bax accelerates staurosporine-induced but suppresses nigericin-induced neuronal cell death
    • Oh J. H. O'Malley K. L., Krajewski S., Reed J. C., and Oh Y. J. (1997) Bax accelerates staurosporine-induced but suppresses nigericin-induced neuronal cell death. Neuroreport 8, 1861-1856.
    • (1997) Neuroreport , vol.8 , pp. 1861-11856
    • Oh, J.H.1    O'Malley, K.L.2    Krajewski, S.3    Reed, J.C.4    Oh, Y.J.5
  • 42
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim R. W. (1991) Cell death during development of the nervous system. Annu. Rev. Neurosci. 14, 453-501.
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 43
    • 0031042902 scopus 로고    scopus 로고
    • Macromolecular substrates for the ICE-like proteases during apoptosis
    • Rosen A. and Casciola-Rosen L. (1997) Macromolecular substrates for the ICE-like proteases during apoptosis. J. Cell. Biochem. 64, 50-54.
    • (1997) J. Cell. Biochem. , vol.64 , pp. 50-54
    • Rosen, A.1    Casciola-Rosen, L.2
  • 44
    • 0029954311 scopus 로고    scopus 로고
    • Potassium deprivation-induced apoptosis of cerebellar granule neurons: A sequential requirement for new mRNa and protein synthesis, ICE-like protease activity, and reactive oxygen species
    • Schulz J. B., Weller M., and Klockgether T. (1996) Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J. Neurosci. 16, 4696-4706.
    • (1996) J. Neurosci. , vol.16 , pp. 4696-4706
    • Schulz, J.B.1    Weller, M.2    Klockgether, T.3
  • 45
    • 0027081202 scopus 로고
    • Changes in neurotrophin responsiveness during the development of cerebellar granule neurons
    • Segal R. A., Takahashi H., and McKay R. D. (1992) Changes in neurotrophin responsiveness during the development of cerebellar granule neurons. Neuron 9, 1041-1052.
    • (1992) Neuron , vol.9 , pp. 1041-1052
    • Segal, R.A.1    Takahashi, H.2    McKay, R.D.3
  • 46
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller H. (1995) Mechanisms and genes of cellular suicide. Science 267, 1445-1449.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 47
    • 0030939043 scopus 로고    scopus 로고
    • Apoptosis in cerebellar granule neurons: Involvement of interleukin-1β-converting enzyme-like proteases
    • Taylor J., Gatchalian C. L., Keen G., and Rubin L. L. (1997) Apoptosis in cerebellar granule neurons: involvement of interleukin-1β-converting enzyme-like proteases. J. Neurochem. 68, 1598-1605.
    • (1997) J. Neurochem. , vol.68 , pp. 1598-1605
    • Taylor, J.1    Gatchalian, C.L.2    Keen, G.3    Rubin, L.L.4
  • 48
    • 0028990125 scopus 로고
    • Yama/CPP32B, a mammalian homolog of CED-3, is a crmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose)polymerase
    • Tewari M., Quan L. G., O'Rourke K., Desnoyers S., Zeng Z., Beidler D. R., Poirier G. G., Salvesan G. S., and Dixit V. M. (1995) Yama/CPP32B, a mammalian homolog of CED-3, is a crmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose)polymerase. Cell 81, 801-809.
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari, M.1    Quan, L.G.2    O'Rourke, K.3    Desnoyers, S.4    Zeng, Z.5    Beidler, D.R.6    Poirier, G.G.7    Salvesan, G.S.8    Dixit, V.M.9
  • 49
    • 0020993019 scopus 로고
    • Observations on rat cerebellar granule cells in vitro: Influence of substratum, potassium concentration and relationship between neurons and astrocytes
    • Thangnipon W., Kingsbury A., Webb M., and Balazs R. (1983) Observations on rat cerebellar granule cells in vitro: influence of substratum, potassium concentration and relationship between neurons and astrocytes. Dev. Brain Res. 11, 177-189.
    • (1983) Dev. Brain Res. , vol.11 , pp. 177-189
    • Thangnipon, W.1    Kingsbury, A.2    Webb, M.3    Balazs, R.4
  • 50
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson C. B. (1995) Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 51
    • 0031018396 scopus 로고    scopus 로고
    • Nedd2 is required for apoptosis after trophic factor withdrawal but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells
    • Troy C. M., Stefanis L., Greene L. A., and Shelanski M. L. (1997) Nedd2 is required for apoptosis after trophic factor withdrawal but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells. J. Neurosci. 17, 1911-1918.
    • (1997) J. Neurosci. , vol.17 , pp. 1911-1918
    • Troy, C.M.1    Stefanis, L.2    Greene, L.A.3    Shelanski, M.L.4
  • 52
    • 0029880987 scopus 로고    scopus 로고
    • The Caenorhabditis elegans cell death protein ced-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease
    • Xue D., Shaham S., and Horvitz H. R. (1996) The Caenorhabditis elegans cell death protein ced-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease. Genes Dev. 10, 1073-1083.
    • (1996) Genes Dev. , vol.10 , pp. 1073-1083
    • Xue, D.1    Shaham, S.2    Horvitz, H.R.3
  • 53
    • 0028133050 scopus 로고
    • Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons
    • Yan G. M., Ni B., Weller M., Wood K., and Paul S. M. (1994) Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons. Brain Res. 656, 43-52.
    • (1994) Brain Res. , vol.656 , pp. 43-52
    • Yan, G.M.1    Ni, B.2    Weller, M.3    Wood, K.4    Paul, S.M.5
  • 54
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian-1β-converting enzyme
    • Yuan J., Shaham S., Ledoux S., Ellis H., and Horvitz H. R. (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian-1β-converting enzyme. Cell 75, 641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.4    Horvitz, H.R.5


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