-
1
-
-
0036084359
-
TGF-beta antagonists: Why suppress a tumor suppressor?
-
Akhurst, R. J. (2002). TGF-beta antagonists: why suppress a tumor suppressor? J. Clin. Invest. 109, 1533-1536.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1533-1536
-
-
Akhurst, R.J.1
-
2
-
-
0032909086
-
Genetic events and the role of TGF beta in epithelial tumour progression
-
Akhurst, R. J. and Balmain, A. (1999). Genetic events and the role of TGF beta in epithelial tumour progression. J. Pathol. 187, 82-90.
-
(1999)
J. Pathol.
, vol.187
, pp. 82-90
-
-
Akhurst, R.J.1
Balmain, A.2
-
3
-
-
0033830945
-
Wnt/beta-catenin signaling
-
Akiyama, T. (2000). Wnt/beta-catenin signaling. Cytokine Growth Factor Rev. 11, 273-282.
-
(2000)
Cytokine Growth Factor Rev.
, vol.11
, pp. 273-282
-
-
Akiyama, T.1
-
4
-
-
0027569092
-
Transforming growth factor beta 1 can induce estrogen-independent tumorigenicity of human breast cancer cells in athymic mice
-
Arteaga, C. L., Carty-Dugger, T., Moses, H. L., Hurd, S. D. and Pietenpol, J. A. (1993). Transforming growth factor beta 1 can induce estrogen-independent tumorigenicity of human breast cancer cells in athymic mice. Cell Growth Differ 4, 193-201.
-
(1993)
Cell Growth Differ.
, vol.4
, pp. 193-201
-
-
Arteaga, C.L.1
Carty-Dugger, T.2
Moses, H.L.3
Hurd, S.D.4
Pietenpol, J.A.5
-
5
-
-
0034469054
-
Transforming growth factor-beta and breast cancer: Mammary gland development
-
Barcellos-Hoff, M. H. and Ewan, K. B. (2000). Transforming growth factor-beta and breast cancer: Mammary gland development. Breast Cancer Res. 2, 92-99.
-
(2000)
Breast Cancer Res.
, vol.2
, pp. 92-99
-
-
Barcellos-Hoff, M.H.1
Ewan, K.B.2
-
6
-
-
0031441041
-
Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene
-
Bottinger, E. P., Jakubczak, J. L., Haines, D. C., Bagnall, K. and Wakefield, L. M. (1997a). Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene. Cancer Res. 57, 5564-5570.
-
(1997)
Cancer Res.
, vol.57
, pp. 5564-5570
-
-
Bottinger, E.P.1
Jakubczak, J.L.2
Haines, D.C.3
Bagnall, K.4
Wakefield, L.M.5
-
7
-
-
0342460497
-
Expression of a dominant-negative mutant TGF-beta type II receptor in transgenic mice reveals essential roles for TGF-beta in regulation of growth and differentiation in the exocrine pancreas
-
Bottinger, E. P., Jakubczak, J. L., Roberts, I. S., Mumy, M., Hemmati, P., Bagnall, K., Merlino, G. and Wakefield, L. M. (1997b). Expression of a dominant-negative mutant TGF-beta type II receptor in transgenic mice reveals essential roles for TGF-beta in regulation of growth and differentiation in the exocrine pancreas. EMBO J. 16, 2621-2633.
-
(1997)
EMBO J.
, vol.16
, pp. 2621-2633
-
-
Bottinger, E.P.1
Jakubczak, J.L.2
Roberts, I.S.3
Mumy, M.4
Hemmati, P.5
Bagnall, K.6
Merlino, G.7
Wakefield, L.M.8
-
8
-
-
0035953393
-
Reducing mammary cancer risk through premature stem cell senescence
-
Boulanger, C. A. and Smith, G. H. (2001). Reducing mammary cancer risk through premature stem cell senescence. Oncogene 20, 2264-2272.
-
(2001)
Oncogene
, vol.20
, pp. 2264-2272
-
-
Boulanger, C.A.1
Smith, G.H.2
-
9
-
-
0035932348
-
Inactivation of p53 tumor suppressor gene acts synergistically with c-neu oncogene in salivary gland tumorigenesis
-
Brodie, S. G., Xu, X., Li, C., Kuo, A., Leder, P. and Deng, C. X. (2001). Inactivation of p53 tumor suppressor gene acts synergistically with c-neu oncogene in salivary gland tumorigenesis. Oncogene 20, 1445-1454.
-
(2001)
Oncogene
, vol.20
, pp. 1445-1454
-
-
Brodie, S.G.1
Xu, X.2
Li, C.3
Kuo, A.4
Leder, P.5
Deng, C.X.6
-
10
-
-
0035874055
-
Impairment of mammary lobular development induced by expression of TGFbeta1 under the control of WAP promoter does not suppress tumorigenesis in MMTV-infected transgenic mice
-
Buggiano, V., Schere-Levy, C., Abe, K., Vanzulli, S., Piazzon, I., Smith, G. H. and Kordon, E. C. (2001). Impairment of mammary lobular development induced by expression of TGFbeta1 under the control of WAP promoter does not suppress tumorigenesis in MMTV-infected transgenic mice. Int. J. Cancer 92, 568-576.
-
(2001)
Int. J. Cancer
, vol.92
, pp. 568-576
-
-
Buggiano, V.1
Schere-Levy, C.2
Abe, K.3
Vanzulli, S.4
Piazzon, I.5
Smith, G.H.6
Kordon, E.C.7
-
11
-
-
0030051927
-
No evidence for mutations in the alpha- and beta-catenin genes in human gastric and breast carcinomas
-
Candidus, S., Bischoff, P., Becker, K. F. and Hofler, H. (1996). No evidence for mutations in the alpha- and beta-catenin genes in human gastric and breast carcinomas. Cancer Res. 56, 49-52.
-
(1996)
Cancer Res.
, vol.56
, pp. 49-52
-
-
Candidus, S.1
Bischoff, P.2
Becker, K.F.3
Hofler, H.4
-
12
-
-
0034696279
-
The mammary pathology of genetically engineered mice: The consensus report and recommendations from the Annapolis meeting
-
Cardiff, R. D., Anver, M. R., Gusterson, B. A., Hennighausen, L., Jensen, R. A., Merino, M. J., Rehm, S., Russo, J., Tavassoli, F. A., Wakefield, L. M., Ward, J. M. and Green, J. E. (2000). The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting. Oncogene 19, 968-988.
-
(2000)
Oncogene
, vol.19
, pp. 968-988
-
-
Cardiff, R.D.1
Anver, M.R.2
Gusterson, B.A.3
Hennighausen, L.4
Jensen, R.A.5
Merino, M.J.6
Rehm, S.7
Russo, J.8
Tavassoli, F.A.9
Wakefield, L.M.10
Ward, J.M.11
Green, J.E.12
-
13
-
-
0033162687
-
Expression and secretion of TGF-beta isoforms and expression of TGF-beta-receptors I, II and III in normal and neoplastic human breast
-
Chakravarthy, D., Green, A. R., Green, V. L., Kerin, M. J. and Speirs, V. (1999). Expression and secretion of TGF-beta isoforms and expression of TGF-beta-receptors I, II and III in normal and neoplastic human breast. Int. J. Oncol. 15, 187-194.
-
(1999)
Int. J. Oncol.
, vol.15
, pp. 187-194
-
-
Chakravarthy, D.1
Green, A.R.2
Green, V.L.3
Kerin, M.J.4
Speirs, V.5
-
14
-
-
0030598681
-
TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
-
Cui, W., Fowlis, D. J., Bryson, S., Duffie, E., Ireland, H., Balmain, A. and Akhurst, R. J. (1996). TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cell 86, 531-542.
-
(1996)
Cell
, vol.86
, pp. 531-542
-
-
Cui, W.1
Fowlis, D.J.2
Bryson, S.3
Duffie, E.4
Ireland, H.5
Balmain, A.6
Akhurst, R.J.7
-
15
-
-
0030251460
-
The role of TGF-beta in patterning and growth of the mammary ductal tree
-
Daniel, C. W., Robinson, S. and Silberstein, G. B. (1996). The role of TGF-beta in patterning and growth of the mammary ductal tree. J. Mamm. Gland Biol. Neoplasia 1, 331-341.
-
(1996)
J. Mamm. Gland Biol. Neoplasia
, vol.1
, pp. 331-341
-
-
Daniel, C.W.1
Robinson, S.2
Silberstein, G.B.3
-
16
-
-
0034748550
-
Knockout mouse models and mammary tumorigenesis
-
Deng, C. X. and Brodie, S. G. (2001). Knockout mouse models and mammary tumorigenesis. Semin. Cancer Biol. 11, 387-394.
-
(2001)
Semin. Cancer Biol.
, vol.11
, pp. 387-394
-
-
Deng, C.X.1
Brodie, S.G.2
-
17
-
-
0034785348
-
TGF-beta signaling in tumor suppression and cancer progression
-
Derynck, R., Akhurst, R. J. and Balmain, A. (2001). TGF-beta signaling in tumor suppression and cancer progression. Nat. Genet. 29, 117-129.
-
(2001)
Nat. Genet.
, vol.29
, pp. 117-129
-
-
Derynck, R.1
Akhurst, R.J.2
Balmain, A.3
-
18
-
-
0035872426
-
Transforming growth factor beta 1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation
-
Ellenrieder, V., Hendler, S. F., Boeck, W., Seufferlein, T., Menke, A., Ruhland, C., Adler, G. and Gress, T. M. (2001). Transforming growth factor beta 1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation. Cancer Res. 61, 4222-4228.
-
(2001)
Cancer Res.
, vol.61
, pp. 4222-4228
-
-
Ellenrieder, V.1
Hendler, S.F.2
Boeck, W.3
Seufferlein, T.4
Menke, A.5
Ruhland, C.6
Adler, G.7
Gress, T.M.8
-
19
-
-
0033601179
-
Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription
-
Engel, M. E., McDonnell, M. A., Law, B. K. and Moses, H. L. (1999). Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription. J. Biol. Chem. 274, 37413-37420.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37413-37420
-
-
Engel, M.E.1
McDonnell, M.A.2
Law, B.K.3
Moses, H.L.4
-
20
-
-
0032771825
-
Frequent 4-bp deletion in exon 9 of the SMAD4/MADH4 gene in familial juvenile polyposis patients
-
Friedl, W., Kruse, R., Uhlhaas, S., Stolte, M., Schartmann, B., Keller, K. M., Jungck, M., Stern, M., Loff, S., Back, W., Propping, P. and Jenne, D. E. (1999). Frequent 4-bp deletion in exon 9 of the SMAD4/MADH4 gene in familial juvenile polyposis patients. Genes Chromosomes Cancer 25, 403-406.
-
(1999)
Genes Chromosomes Cancer
, vol.25
, pp. 403-406
-
-
Friedl, W.1
Kruse, R.2
Uhlhaas, S.3
Stolte, M.4
Schartmann, B.5
Keller, K.M.6
Jungck, M.7
Stern, M.8
Loff, S.9
Back, W.10
Propping, P.11
Jenne, D.E.12
-
21
-
-
0031927686
-
Dominant-negative interference of the transforming growth factor beta type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice
-
Gorska, A. E., Joseph, H., Derynck, R., Moses, H. L. and Serra, R. (1998). Dominant-negative interference of the transforming growth factor beta type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice. Cell Growth Differ 9, 229-238.
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 229-238
-
-
Gorska, A.E.1
Joseph, H.2
Derynck, R.3
Moses, H.L.4
Serra, R.5
-
22
-
-
9044243025
-
Homozygous deletion map at 18q21.1 in pancreatic cancer
-
Hahn, S. A., Hoque, A. T., Moskaluk, C. A., da Costa, L. T., Schutte, M., Rozenblum, E., Seymour, A. B., Weinstein, C. L., Yeo, C. J., Hruban, R. H. and Kern, S. E. (1996a). Homozygous deletion map at 18q21.1 in pancreatic cancer. Cancer Res. 56, 490-494.
-
(1996)
Cancer Res.
, vol.56
, pp. 490-494
-
-
Hahn, S.A.1
Hoque, A.T.2
Moskaluk, C.A.3
da Costa, L.T.4
Schutte, M.5
Rozenblum, E.6
Seymour, A.B.7
Weinstein, C.L.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
23
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn, S. A., Schutte, M., Hoque, A. T., Moskaluk, C. A., da Costa, L. T., Rozenblum, E., Weinstein, C. L., Fischer, A., Yeo, C. J., Hruban, R. H. and Kern, S. E. (1996b). DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271, 350-353.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Moskaluk, C.A.4
da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
24
-
-
0031438047
-
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
-
Heldin, C. H., Miyazono, K. and ten Dijke, P. (1997). TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 390, 465-471.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
ten Dijke, P.3
-
25
-
-
0035489712
-
Signaling pathways in mammary gland development
-
Hennighausen, L. and Robinson, G. W. (2001). Signaling pathways in mammary gland development. Dev. Cell 1, 467-475.
-
(2001)
Dev. Cell
, vol.1
, pp. 467-475
-
-
Hennighausen, L.1
Robinson, G.W.2
-
26
-
-
0033104505
-
TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway
-
Hocevar, B. A., Brown, T. L. and Howe, P. H. (1999). TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway. EMBO J. 18, 1345-1356.
-
(1999)
EMBO J.
, vol.18
, pp. 1345-1356
-
-
Hocevar, B.A.1
Brown, T.L.2
Howe, P.H.3
-
27
-
-
0032524069
-
Mutations in the SMAD4/DPC4 gene in juvenile polyposis
-
Howe, J. R., Roth, S., Ringold, J. C., Summers, R. W., Jarvinen, H. J., Sistonen, P., Tomlinson, I. P., Houlston, R. S., Bevan, S., Mitros, F. A., Stone, E. M. and Aaltonen, L. A. (1998). Mutations in the SMAD4/DPC4 gene in juvenile polyposis. Science 280, 1086-1088.
-
(1998)
Science
, vol.280
, pp. 1086-1088
-
-
Howe, J.R.1
Roth, S.2
Ringold, J.C.3
Summers, R.W.4
Jarvinen, H.J.5
Sistonen, P.6
Tomlinson, I.P.7
Houlston, R.S.8
Bevan, S.9
Mitros, F.A.10
Stone, E.M.11
Aaltonen, L.A.12
-
28
-
-
0032910954
-
Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branching
-
Joseph, H., Gorska, A. E., Sohn, P., Moses, H. L. and Serra, R. (1999). Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branching. Mol. Biol. Cell 10, 1221-1234.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 1221-1234
-
-
Joseph, H.1
Gorska, A.E.2
Sohn, P.3
Moses, H.L.4
Serra, R.5
-
29
-
-
0035093364
-
Expression patterns of beta-catenin in in situ and invasive breast cancer
-
Karayiannakis, A. J., Nakopoulou, L., Gakiopoulou, H., Keramopoulos, A., Davaris, P. S. and Pignatelli, M. (2001). Expression patterns of beta-catenin in in situ and invasive breast cancer. Eur. J. Surg. Oncol. 27, 31-36.
-
(2001)
Eur. J. Surg. Oncol.
, vol.27
, pp. 31-36
-
-
Karayiannakis, A.J.1
Nakopoulou, L.2
Gakiopoulou, H.3
Keramopoulos, A.4
Davaris, P.S.5
Pignatelli, M.6
-
30
-
-
0033106484
-
A mechanism of repression of TGFbeta/ Smad signaling by oncogenic
-
Kretzschmar, M., Doody, J., Timokhina, I. and Massague, J. (1999). A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras. Genes Dev. 13, 804-816.
-
(1999)
Ras. Genes Dev.
, vol.13
, pp. 804-816
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
Massague, J.4
-
31
-
-
0031685620
-
TGF-beta signal transduction
-
Massague, J. (1998). TGF-beta signal transduction. Annu. Rev. Biochem. 67, 753-791.
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
32
-
-
0037039355
-
Activation of beta-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias
-
Miyoshi, K., Shillingford, J. M., le Provost, F., Gounari, F., Bronson, R., von Boehmer, H., Taketo, M. M., Cardiff, R. D., Hennighausen, L. and Khazaie, K. (2002). Activation of beta-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias. Proc. Natl. Acad. Sci. USA 99, 219-224.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 219-224
-
-
Miyoshi, K.1
Shillingford, J.M.2
le Provost, F.3
Gounari, F.4
Bronson, R.5
von Boehmer, H.6
Taketo, M.M.7
Cardiff, R.D.8
Hennighausen, L.9
Khazaie, K.10
-
33
-
-
0034023127
-
Role of Ras and Mapks in TGFbeta signaling
-
Mulder, K. M. (2000). Role of Ras and Mapks in TGFbeta signaling. Cytokine Growth Factor Rev. 11, 23-35.
-
(2000)
Cytokine Growth Factor Rev.
, vol.11
, pp. 23-35
-
-
Mulder, K.M.1
-
34
-
-
0036086409
-
Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases
-
Muraoka, R. S., Dumont, N., Ritter, C. A., Dugger, T. C., Brantley, D. M., Chen, J., Easterly, E., Roebuck, L. R., Ryan, S., Gotwals, P. J., Koteliansky, V. and Arteaga, C. L. (2002). Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases. J. Clin. Invest. 109, 1551-1559.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1551-1559
-
-
Muraoka, R.S.1
Dumont, N.2
Ritter, C.A.3
Dugger, T.C.4
Brantley, D.M.5
Chen, J.6
Easterly, E.7
Roebuck, L.R.8
Ryan, S.9
Gotwals, P.J.10
Koteliansky, V.11
Arteaga, C.L.12
-
35
-
-
0033858512
-
Transforming growth factor beta3 induces cell death during the first stage of mammary gland involution
-
Nguyen, A. V. and Pollard, J. W. (2000). Transforming growth factor beta3 induces cell death during the first stage of mammary gland involution. Development 127, 3107-3118.
-
(2000)
Development
, vol.127
, pp. 3107-3118
-
-
Nguyen, A.V.1
Pollard, J.W.2
-
36
-
-
0036304111
-
Metastasis is driven by sequential elevation of H-ras and Smad2 levels
-
Oft, M., Akhurst, R. J. and Balmain, A. (2002). Metastasis is driven by sequential elevation of H-ras and Smad2 levels. Nat. Cell Biol. 4, 487-494.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 487-494
-
-
Oft, M.1
Akhurst, R.J.2
Balmain, A.3
-
37
-
-
0029662049
-
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
-
Oft, M., Peli, J., Rudaz, C., Schwarz, H., Beug, H. and Reichmann, E. (1996). TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev. 10, 2462-2477.
-
(1996)
Genes Dev.
, vol.10
, pp. 2462-2477
-
-
Oft, M.1
Peli, J.2
Rudaz, C.3
Schwarz, H.4
Beug, H.5
Reichmann, E.6
-
38
-
-
0032763469
-
Specificity, diversity, and regulation in TGF-beta superfamily signaling
-
Piek, E., Heldin, C. H. and ten Dijke, P. (1999a). Specificity, diversity, and regulation in TGF-beta superfamily signaling. FASEB J. 13, 2105-2124.
-
(1999)
FASEB J.
, vol.13
, pp. 2105-2124
-
-
Piek, E.1
Heldin, C.H.2
ten Dijke, P.3
-
39
-
-
0033377867
-
TGF-(beta) type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells
-
Piek, E., Moustakas, A., Kurisaki, A., Heldin, C. H. and ten Dijke, P. (1999b). TGF-(beta) type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells. J. Cell Sci. 112, 4557-4568.
-
(1999)
J. Cell Sci.
, vol.112
, pp. 4557-4568
-
-
Piek, E.1
Moustakas, A.2
Kurisaki, A.3
Heldin, C.H.4
ten Dijke, P.5
-
40
-
-
0029010734
-
Mammary tumor suppression by transforming growth factor beta 1 transgene expression
-
Pierce, D. F., Jr, Gorska, A. E., Chytil, A., Meise, K. S., Page, D. L., Coffey, R. J., Jr and Moses, H. L. (1995). Mammary tumor suppression by transforming growth factor beta 1 transgene expression. Proc. Natl. Acad. Sci. USA 92, 4254-4258.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4254-4258
-
-
Pierce Jr., D.F.1
Gorska, A.E.2
Chytil, A.3
Meise, K.S.4
Page, D.L.5
Coffey Jr., R.J.6
Moses, H.L.7
-
41
-
-
0035369302
-
More than one way to skin a catenin
-
Polakis, P. (2001). More than one way to skin a catenin. Cell 105, 563-566.
-
(2001)
Cell
, vol.105
, pp. 563-566
-
-
Polakis, P.1
-
42
-
-
0031817391
-
Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: Implications for tumor invasion
-
Portella, G., Cumming, S. A., Liddell, J., Cui, W., Ireland, H., Akhurst, R. J. and Balmain, A. (1998). Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion. Cell Growth Differ. 9, 393-404.
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 393-404
-
-
Portella, G.1
Cumming, S.A.2
Liddell, J.3
Cui, W.4
Ireland, H.5
Akhurst, R.J.6
Balmain, A.7
-
43
-
-
0030873168
-
Inhibins and activins regulate mammary epithelial cell differentiation through mesenchymal-epithelial interactions
-
Robinson, G. W. and Hennighausen, L. (1997). Inhibins and activins regulate mammary epithelial cell differentiation through mesenchymal-epithelial interactions. Development 124, 2701-2708.
-
(1997)
Development
, vol.124
, pp. 2701-2708
-
-
Robinson, G.W.1
Hennighausen, L.2
-
44
-
-
0034020480
-
Suppression of polypogenesis in a new mouse strain with a truncated Apc(Delta474) by a novel COX-2 inhibitor, JTE-522
-
Sasai, H., Masaki, M. and Wakitani, K. (2000). Suppression of polypogenesis in a new mouse strain with a truncated Apc(Delta474) by a novel COX-2 inhibitor, JTE-522. Carcinogenesis 21, 953-958.
-
(2000)
Carcinogenesis
, vol.21
, pp. 953-958
-
-
Sasai, H.1
Masaki, M.2
Wakitani, K.3
-
45
-
-
0023631608
-
Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo
-
Sinn, E., Muller, W., Pattengale, P., Tepler, I., Wallace, R. and Leder, P. (1987). Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo. Cell 49, 465-475.
-
(1987)
Cell
, vol.49
, pp. 465-475
-
-
Sinn, E.1
Muller, W.2
Pattengale, P.3
Tepler, I.4
Wallace, R.5
Leder, P.6
-
46
-
-
15444348295
-
The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo
-
Sirard, C., de la Pompa, J. L., Elia, A., Itie, A., Mirtsos, C., Cheung, A., Hahn, S., Wakeham, A., Schwartz, L., Kern, S. E., Rossant, J. and Mak, T. W. (1998). The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo. Genes Dev. 12, 107-119.
-
(1998)
Genes Dev.
, vol.12
, pp. 107-119
-
-
Sirard, C.1
de la Pompa, J.L.2
Elia, A.3
Itie, A.4
Mirtsos, C.5
Cheung, A.6
Hahn, S.7
Wakeham, A.8
Schwartz, L.9
Kern, S.E.10
Rossant, J.11
Mak, T.W.12
-
47
-
-
0034234268
-
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice
-
Stambolic, V., Tsao, M. S., Macpherson, D., Suzuki, A., Chapman, W. B. and Mak, T. W. (2000). High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice. Cancer Res. 60, 3605-3611.
-
(2000)
Cancer Res.
, vol.60
, pp. 3605-3611
-
-
Stambolic, V.1
Tsao, M.S.2
Macpherson, D.3
Suzuki, A.4
Chapman, W.B.5
Mak, T.W.6
-
48
-
-
0030456980
-
Allelotype of adenoma and differentiated adenocarcinoma of the stomach
-
Tamura, G., Sakata, K., Nishizuka, S., Maesawa, C., Suzuki, Y., Terashima, M., Eda, Y. and Satodate, R. (1996). Allelotype of adenoma and differentiated adenocarcinoma of the stomach. J. Pathol. 180, 371-377.
-
(1996)
J. Pathol.
, vol.180
, pp. 371-377
-
-
Tamura, G.1
Sakata, K.2
Nishizuka, S.3
Maesawa, C.4
Suzuki, Y.5
Terashima, M.6
Eda, Y.7
Satodate, R.8
-
49
-
-
0030658840
-
Cre-mediated gene deletion in the mammary gland
-
Wagner, K. U., Wall, R. J., St-Onge, L., Gruss, P., Wynshaw-Boris, A., Garrett, L., Li, M., Furth, P. A. and Hennighausen, L. (1997). Cre-mediated gene deletion in the mammary gland. Nucleic Acids Res. 25, 4323-4330.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 4323-4330
-
-
Wagner, K.U.1
Wall, R.J.2
St-Onge, L.3
Gruss, P.4
Wynshaw-Boris, A.5
Garrett, L.6
Li, M.7
Furth, P.A.8
Hennighausen, L.9
-
50
-
-
0035230598
-
TGF-beta signaling in mammary gland development and tumorigenesis
-
Wakefield, L. M., Piek, E. and Bottinger, E. P. (2001). TGF-beta signaling in mammary gland development and tumorigenesis. J Mamm. Gland Biol. Neoplasia 6, 67-82.
-
(2001)
J. Mamm. Gland Biol. Neoplasia
, vol.6
, pp. 67-82
-
-
Wakefield, L.M.1
Piek, E.2
Bottinger, E.P.3
-
51
-
-
0036467496
-
TGF-beta signaling: Positive and negative effects on tumorigenesis
-
Wakefield, L. M. and Roberts, A. B. (2002). TGF-beta signaling: positive and negative effects on tumorigenesis. Curr. Opin. Genet. Dev. 12, 22-29.
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 22-29
-
-
Wakefield, L.M.1
Roberts, A.B.2
-
52
-
-
0034002124
-
Transforming growth factor beta and its receptors: Their role in breast cancer
-
Walker, R. A. (2000). Transforming growth factor beta and its receptors: their role in breast cancer. Histopathology 36, 178-180.
-
(2000)
Histopathology
, vol.36
, pp. 178-180
-
-
Walker, R.A.1
-
53
-
-
0034023371
-
Functions of mammalian Smad genes as revealed by targeted gene disruption in mice
-
Weinstein, M., Yang, X. and Deng, C. (2000). Functions of mammalian Smad genes as revealed by targeted gene disruption in mice. Cytokine Growth Factor Rev. 11, 49-58.
-
(2000)
Cytokine Growth Factor Rev.
, vol.11
, pp. 49-58
-
-
Weinstein, M.1
Yang, X.2
Deng, C.3
-
54
-
-
0032587877
-
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation
-
Xu, X., Wagner, K. U., Larson, D., Weaver, Z., Li, C., Ried, T., Hennighausen, L., Wynshaw-Boris, A. and Deng, C. X. (1999). Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. Nat. Genet. 22, 37-43.
-
(1999)
Nat. Genet.
, vol.22
, pp. 37-43
-
-
Xu, X.1
Wagner, K.U.2
Larson, D.3
Weaver, Z.4
Li, C.5
Ried, T.6
Hennighausen, L.7
Wynshaw-Boris, A.8
Deng, C.X.9
-
55
-
-
0032584068
-
The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice
-
Yang, X., Li, C., Xu, X. and Deng, C. (1998). The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice. Proc. Natl. Acad. Sci. USA 95, 3667-3672.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 3667-3672
-
-
Yang, X.1
Li, C.2
Xu, X.3
Deng, C.4
-
56
-
-
0036193069
-
Generation of Smad4/Dpc4 conditional knockout mice
-
Yang, X., Li, C., Herrera, P. L. and Deng, C. X. (2002a). Generation of Smad4/Dpc4 conditional knockout mice. Genesis 32, 80-81.
-
(2002)
Genesis
, vol.32
, pp. 80-81
-
-
Yang, X.1
Li, C.2
Herrera, P.L.3
Deng, C.X.4
-
57
-
-
0036087521
-
Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects
-
Yang, Y. A., Dukhanina, O., Tang, B., Mamura, M., Letterio, J. J., MacGregor, J., Patel, S. C., Khozin, S., Liu, Z. Y., Green, J., Anver, M. R., Merlino, G. and Wakefield, L. M. (2002b). Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects. J. Clin. Invest. 109, 1607-1615.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1607-1615
-
-
Yang, Y.A.1
Dukhanina, O.2
Tang, B.3
Mamura, M.4
Letterio, J.J.5
MacGregor, J.6
Patel, S.C.7
Khozin, S.8
Liu, Z.Y.9
Green, J.10
Anver, M.R.11
Merlino, G.12
Wakefield, L.M.13
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