Activation of β-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 1, 2002, Pages 219-224

  Miyoshi, Keiko ^a,f   Shillingford, Jonathan M ^a   Le Provost, Fabienne ^a,b   Gounari, Fotini ^c   Bronson, Roderick ^c   Von Boehmer, Harald ^c   Taketo, Makoto M ^d   Cardiff, Robert D ^e   Hennighausen, Lothar ^a   Khazaie, Khashayarsha ^c  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b CEMAGREF   (France)

^c HARVARD MEDICAL SCHOOL   (United States)

^d KYOTO UNIVERSITY   (Japan)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Cell identity; Cre; Dedifferentiation; Mammary gland; Wnt signaling

Indexed keywords

BETA CATENIN; GENE PRODUCT; LYMPHOID ENHANCER FACTOR 1; UNCLASSIFIED DRUG; WHEY ACIDIC PROTEIN;

ADENOCARCINOMA; ANIMAL CELL; ARTICLE; BREAST EPITHELIUM; CELL DIFFERENTIATION; CELL STRUCTURE; CELL TRANSFORMATION; CONTROLLED STUDY; EPIDERMIS; GENE ACTIVATION; GENE DELETION; LONG TERMINAL REPEAT; MOUSE; NERVE FIBER; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN STABILITY; SECRETORY CELL; SIGNAL TRANSDUCTION; SQUAMOUS CELL METAPLASIA; TRANSGENIC MOUSE;

ADENOCARCINOMA; ANIMALS; BETA CATENIN; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL DIFFERENTIATION; CYTOPLASM; CYTOSKELETAL PROTEINS; EPIDERMIS; EXONS; GENE DELETION; IMMUNOHISTOCHEMISTRY; METAPLASIA; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; MILK PROTEINS; MODELS, BIOLOGICAL; PROMOTER REGIONS (GENETICS); SIGNAL TRANSDUCTION; TIME FACTORS; TRANS-ACTIVATORS;

ANIMALIA; MOUSE MAMMARY TUMOR VIRUS; MUS MUSCULUS;

EID: 0037039355     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.012414099     Document Type: Article

References (20)