-
1
-
-
0028267236
-
Location of stem cells of human hair follicles by clonal analysis
-
Rochat A, Konayashi K, Barrandon Y. Location of stem cells of human hair follicles by clonal analysis. Cell 1994; 76: 1063-1073.
-
(1994)
Cell
, vol.76
, pp. 1063-1073
-
-
Rochat, A.1
Konayashi, K.2
Barrandon, Y.3
-
3
-
-
0025313294
-
Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
-
Cotsarelis G, Sun T-T, Lavker RM. Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 1990; 61: 1329-1337.
-
(1990)
Cell
, vol.61
, pp. 1329-1337
-
-
Cotsarelis, G.1
Sun, T.-T.2
Lavker, R.M.3
-
4
-
-
0025641727
-
Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties: Lessons from the crypt
-
Potten CS, Loeffler M. Stem cells: attributes, cycles, spirals, pitfalls and uncertainties: lessons from the crypt. Development 1990; 110: 1001-1020.
-
(1990)
Development
, vol.110
, pp. 1001-1020
-
-
Potten, C.S.1
Loeffler, M.2
-
5
-
-
0024523631
-
Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells
-
Cotsarelis G, Cheng S-Z, Dong G, Sun T-TLRM. Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells. Cell 1989; 57: 21.
-
(1989)
Cell
, vol.57
, pp. 21
-
-
Cotsarelis, G.1
Cheng, S.-Z.2
Dong, G.3
Sun, T.-T.L.R.M.4
-
6
-
-
0026074818
-
Co-operation between oncogenes
-
Hunter T. Co-operation between oncogenes. Cell 1991; 64: 249-270.
-
(1991)
Cell
, vol.64
, pp. 249-270
-
-
Hunter, T.1
-
7
-
-
0024399684
-
Oncogenes, anti-oncogenes and the molecular bases of multistep carcinogenesis
-
Weinberg RA. Oncogenes, anti-oncogenes and the molecular bases of multistep carcinogenesis. Cancer Res 1989; 49: 3713-3721.
-
(1989)
Cancer Res
, vol.49
, pp. 3713-3721
-
-
Weinberg, R.A.1
-
8
-
-
0026361479
-
Functional loss of tumour suppressor genes in multi-stage chemical carcinogenesis
-
Balmain A, Kemp CJ, Burns PA, Stoler AB, Fowlis DJ, Akhurst RJ. Functional loss of tumour suppressor genes in multi-stage chemical carcinogenesis. Princess Takematsu Symp 1991; 22: 97-108.
-
(1991)
Princess Takematsu Symp
, vol.22
, pp. 97-108
-
-
Balmain, A.1
Kemp, C.J.2
Burns, P.A.3
Stoler, A.B.4
Fowlis, D.J.5
Akhurst, R.J.6
-
9
-
-
0028081191
-
Human tumor vaccines and genetic engineering of tumors with cytokine and histocompalibility genes to enhance immunogenicity
-
Rosenthal FM. Human tumor vaccines and genetic engineering of tumors with cytokine and histocompalibility genes to enhance immunogenicity. Curr Opin Oncol 1994; 6: 611-615.
-
(1994)
Curr Opin Oncol
, vol.6
, pp. 611-615
-
-
Rosenthal, F.M.1
-
10
-
-
0022179539
-
Induction of papillomas with a high probability of conversion to malignancy
-
Hennings H, Spangler EF, Shores R, et al. Induction of papillomas with a high probability of conversion to malignancy. Carcinogenesis 1985; 6: 1607-1610.
-
(1985)
Carcinogenesis
, vol.6
, pp. 1607-1610
-
-
Hennings, H.1
Spangler, E.F.2
Shores, R.3
-
11
-
-
0024469982
-
Multistage chemical carcinogenesis protocols produce spindle cell carcinomas of the mouse skin
-
Klein-Szanto AJ, Larcher F, Bonfil RD, Conn CJ. Multistage chemical carcinogenesis protocols produce spindle cell carcinomas of the mouse skin. Carcinogenesis 1989; 10: 2169-2172.
-
(1989)
Carcinogenesis
, vol.10
, pp. 2169-2172
-
-
Klein-Szanto, A.J.1
Larcher, F.2
Bonfil, R.D.3
Conn, C.J.4
-
12
-
-
0027200650
-
The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event
-
Stoler A, Stenback F, Balmain A. The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event. J Cell Biol 1993; 122: 1103-1117.
-
(1993)
J Cell Biol
, vol.122
, pp. 1103-1117
-
-
Stoler, A.1
Stenback, F.2
Balmain, A.3
-
13
-
-
0030034510
-
The expression of the cell adhesion molecules E-cadherin, P-cadherin and α6β4 integrin is altered in premalignant skin tumours of p53-deficient mice
-
Cano A, Gamalla C, Kemp CJ, et al. The expression of the cell adhesion molecules E-cadherin, P-cadherin and α6β4 integrin is altered in premalignant skin tumours of p53-deficient mice. Int J Cancer 1996; 65: 254-262.
-
(1996)
Int J Cancer
, vol.65
, pp. 254-262
-
-
Cano, A.1
Gamalla, C.2
Kemp, C.J.3
-
14
-
-
0025932528
-
A role for the E-cadherin cell cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis
-
Navarro P, Gomez M, Pizarro A, Gamallo C, Quintanilla M, Cano A. A role for the E-cadherin cell cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis. J Cell Biol 1991; 115: 517-533.
-
(1991)
J Cell Biol
, vol.115
, pp. 517-533
-
-
Navarro, P.1
Gomez, M.2
Pizarro, A.3
Gamallo, C.4
Quintanilla, M.5
Cano, A.6
-
15
-
-
0011493380
-
Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons
-
Bizub D, Wood AW, Skalka AM. Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons. Proc Natl Acad Sci USA 1986; 83: 6048-6051.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 6048-6051
-
-
Bizub, D.1
Wood, A.W.2
Skalka, A.M.3
-
16
-
-
0022527161
-
Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
-
Quintanilla M, Brown K, Ramsden M, Balmain A. Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature (London) 1986; 322: 78-80.
-
(1986)
Nature (London)
, vol.322
, pp. 78-80
-
-
Quintanilla, M.1
Brown, K.2
Ramsden, M.3
Balmain, A.4
-
17
-
-
0021871265
-
Direct mutagenests of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats
-
Zarbl H, Sukumar S, Arthur AV, Martin-Zanca D, Barbacid M. Direct mutagenests of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats. Nature 1985; 315: 382-385.
-
(1985)
Nature
, vol.315
, pp. 382-385
-
-
Zarbl, H.1
Sukumar, S.2
Arthur, A.V.3
Martin-Zanca, D.4
Barbacid, M.5
-
18
-
-
0025038030
-
Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression
-
Brown K, Buchmann A, Balmain A. Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression. Proc Natl Acad Sci USA 1990; 87: 538-542.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 538-542
-
-
Brown, K.1
Buchmann, A.2
Balmain, A.3
-
19
-
-
0022977903
-
An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue
-
Roop DR, Lowy DR, Tambourin PE, et al. An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue. Nature 1986; 323: 822-824.
-
(1986)
Nature
, vol.323
, pp. 822-824
-
-
Roop, D.R.1
Lowy, D.R.2
Tambourin, P.E.3
-
20
-
-
0022458856
-
v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis
-
Brown K, Quintanilla M, Ramsden M, Kerr IB, Young S, Balmain A. v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis. Cell 1986; 46: 447-456.
-
(1986)
Cell
, vol.46
, pp. 447-456
-
-
Brown, K.1
Quintanilla, M.2
Ramsden, M.3
Kerr, I.B.4
Young, S.5
Balmain, A.6
-
21
-
-
0025986954
-
Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo
-
Quintanilla M, Haddow S, Jonas D, Jaffe D, Bowden GT, Balmain A. Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo. Carcinogenesis 1991; 12: 1875-1881.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1875-1881
-
-
Quintanilla, M.1
Haddow, S.2
Jonas, D.3
Jaffe, D.4
Bowden, G.T.5
Balmain, A.6
-
22
-
-
0025365140
-
Genetic changes in skin tumor progression: Correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7
-
Bremner R, Balmain A. Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7. Cell 1990; 61: 407-417.
-
(1990)
Cell
, vol.61
, pp. 407-417
-
-
Bremner, R.1
Balmain, A.2
-
23
-
-
0028138796
-
Induction of different genetic changes by different classes ol chemical carcinogens during progression of mouse skin tumors
-
Bremner R, Kemp CJ, Balmain A. Induction of different genetic changes by different classes ol chemical carcinogens during progression of mouse skin tumors. Mol Carcinog 1994; 11: 90-97.
-
(1994)
Mol Carcinog
, vol.11
, pp. 90-97
-
-
Bremner, R.1
Kemp, C.J.2
Balmain, A.3
-
24
-
-
0025052266
-
Nonrandom duplication of the chromosome bearing it mutated Ha-ras-1 allele in mouse skin tumors
-
Bianchi AB, Aldaz CM, Conti CJ. Nonrandom duplication of the chromosome bearing it mutated Ha-ras-1 allele in mouse skin tumors. Proc Nall Acad Sci USA 1990; 87: 6902-6906.
-
(1990)
Proc Nall Acad Sci USA
, vol.87
, pp. 6902-6906
-
-
Bianchi, A.B.1
Aldaz, C.M.2
Conti, C.J.3
-
26
-
-
0025166072
-
Graded changes in dose of a Xenopus activin a homologue elicit stepwise transitions in embryonic cell fate
-
Green JBA, Smith JC. Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate. Nature 1990; 347: 391-394.
-
(1990)
Nature
, vol.347
, pp. 391-394
-
-
Green, J.B.A.1
Smith, J.C.2
-
27
-
-
0026611442
-
Involvement of p21ras in Xenopus mesoderm induction
-
Whitman M, Melton DA. Involvement of p21ras in Xenopus mesoderm induction. Nature 1992; 357: 252-254.
-
(1992)
Nature
, vol.357
, pp. 252-254
-
-
Whitman, M.1
Melton, D.A.2
-
28
-
-
0026611053
-
Involvement of p21ras in activation of extracellular signal-regulated kinase 2
-
de Vries-Smits AM, Burgering BM, Leevers SJ, Marshall CJ, Bos JL. Involvement of p21ras in activation of extracellular signal-regulated kinase 2. Nature 1992; 357: 602-604.
-
(1992)
Nature
, vol.357
, pp. 602-604
-
-
De Vries-Smits, A.M.1
Burgering, B.M.2
Leevers, S.J.3
Marshall, C.J.4
Bos, J.L.5
-
29
-
-
0028152333
-
MAP kinase kinase kinase. MAP kinase kinase and MAP kinase
-
Marshall CJ. MAP kinase kinase kinase. MAP kinase kinase and MAP kinase. Curr Opin Genet Dev 1994; 4: 82-89.
-
(1994)
Curr Opin Genet Dev
, vol.4
, pp. 82-89
-
-
Marshall, C.J.1
-
32
-
-
0025041030
-
Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a saprabasal keratin promotor
-
Bailleul B, Surani MA, White S, et al. Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a saprabasal keratin promotor. Cell 1990; 62: 697-708.
-
(1990)
Cell
, vol.62
, pp. 697-708
-
-
Bailleul, B.1
Surani, M.A.2
White, S.3
-
33
-
-
0027516110
-
Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene
-
Greenhalgh DA, Rothnagel JA, Quintanilla MI, et al. Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene. Mol Carcinog 1993; 7: 99-110.
-
(1993)
Mol Carcinog
, vol.7
, pp. 99-110
-
-
Greenhalgh, D.A.1
Rothnagel, J.A.2
Quintanilla, M.I.3
-
34
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p161NK4a
-
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p161NK4a. Cell 1997; 88: 593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
35
-
-
0027359975
-
Cooperation between v-fos and v-rasHA induces autonomous papillomas in transgenic epidermis but not malignant conversion
-
Greenhalgh DA, Quintanilla MI, Orengo CC, et al. Cooperation between v-fos and v-rasHA induces autonomous papillomas in transgenic epidermis but not malignant conversion. Cancer Res 1993; 53: 5071-5075.
-
(1993)
Cancer Res
, vol.53
, pp. 5071-5075
-
-
Greenhalgh, D.A.1
Quintanilla, M.I.2
Orengo, C.C.3
-
36
-
-
0032559976
-
The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted
-
Brown K, Strathdee D, Bryson S, Lambie W, Balmain A. The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted. Curr Biol 1998; 8: 516-524.
-
(1998)
Curr Biol
, vol.8
, pp. 516-524
-
-
Brown, K.1
Strathdee, D.2
Bryson, S.3
Lambie, W.4
Balmain, A.5
-
37
-
-
0026349058
-
Loss of heterozygosity and mutational alterations of the p53 gene in skin tumors of interspecific hybrid mice
-
Burns PA, Kemp CJ, Gannon JV, Lane DP, Bremner R, Balmain A. Loss of heterozygosity and mutational alterations of the p53 gene in skin tumors of interspecific hybrid mice. Oncogene 1991; 6: 2363-2369.
-
(1991)
Oncogene
, vol.6
, pp. 2363-2369
-
-
Burns, P.A.1
Kemp, C.J.2
Gannon, J.V.3
Lane, D.P.4
Bremner, R.5
Balmain, A.6
-
38
-
-
0027500049
-
Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene
-
Ruggeri B, DiRado M, Zhang SY, Bauer B, Goodrow T, Klein-Szanto AJ. Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene. Proc Natl Acad Sci USA 1993; 90: 1013-1017.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1013-1017
-
-
Ruggeri, B.1
DiRado, M.2
Zhang, S.Y.3
Bauer, B.4
Goodrow, T.5
Klein-Szanto, A.J.6
-
39
-
-
0028673459
-
Transgenic approaches to the analysis of ras and p53 function in multistage carcinogenesis
-
Kemp CJ, Burns PA, Brown K, Nagase H, Balmain A. Transgenic approaches to the analysis of ras and p53 function in multistage carcinogenesis. Cold Spring Harbor Symp Quant Biol 1994; 59: 427-434.
-
(1994)
Cold Spring Harbor Symp Quant Biol
, vol.59
, pp. 427-434
-
-
Kemp, C.J.1
Burns, P.A.2
Brown, K.3
Nagase, H.4
Balmain, A.5
-
40
-
-
0027166864
-
Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers
-
Ziegler A, Leffell DJ, Kunala S, et al. Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers. Proc Natl Acad Sci USA 1993; 90: 4216-4220.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4216-4220
-
-
Ziegler, A.1
Leffell, D.J.2
Kunala, S.3
-
41
-
-
0029836835
-
Signature p53 mutation at DNA cross-linking sites in 8-methoxypsoralen and ultraviolet A (PUVA)-induced murine skin cancers
-
Nataraj AJ, Black HS, Ananthaswamy HN. Signature p53 mutation at DNA cross-linking sites in 8-methoxypsoralen and ultraviolet A (PUVA)-induced murine skin cancers. Proc Natl Acad Sci USA 1996; 93: 7961-7965.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7961-7965
-
-
Nataraj, A.J.1
Black, H.S.2
Ananthaswamy, H.N.3
-
42
-
-
0027203921
-
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors
-
Kemp CJ, Donehower LA, Bradley A, Balmain A. Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors. Cell 1993; 74: 813-822.
-
(1993)
Cell
, vol.74
, pp. 813-822
-
-
Kemp, C.J.1
Donehower, L.A.2
Bradley, A.3
Balmain, A.4
-
43
-
-
0029782220
-
Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha
-
Greenhalgh DA, Wang XJ, Donehower LA, Roop DR. Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha. Cancer Res 1996; 56: 4413-4423
-
(1996)
Cancer Res
, vol.56
, pp. 4413-4423
-
-
Greenhalgh, D.A.1
Wang, X.J.2
Donehower, L.A.3
Roop, D.R.4
-
44
-
-
0030460978
-
The p53 response to ionising radiation in adult and developing murine tissues
-
MacCallum DE, Hupp TR, Midgley CA, et al. The p53 response to ionising radiation in adult and developing murine tissues. Oncogene 1996; 13: 2575-2587.
-
(1996)
Oncogene
, vol.13
, pp. 2575-2587
-
-
MacCallum, D.E.1
Hupp, T.R.2
Midgley, C.A.3
-
45
-
-
0031852337
-
Cloning and functional analysis of human p51, which structurally and functionally resembles p53
-
Osada M, Ohba M, Kawahara C, et al. Cloning and functional analysis of human p51, which structurally and functionally resembles p53. Nature Med 1998; 4: 839-843.
-
(1998)
Nature Med
, vol.4
, pp. 839-843
-
-
Osada, M.1
Ohba, M.2
Kawahara, C.3
-
46
-
-
0025765115
-
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells
-
Frixen UH, Behrens J, Sachs M, et al. E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 1991; 113: 173-185.
-
(1991)
J Cell Biol
, vol.113
, pp. 173-185
-
-
Frixen, U.H.1
Behrens, J.2
Sachs, M.3
-
47
-
-
0027550662
-
Urokinase and urokinase receptor: A paracrine/autocrine system regulating cell migration and invasiveness
-
Blasi F. Urokinase and urokinase receptor: a paracrine/autocrine system regulating cell migration and invasiveness. BioEssays 1993; 15: 105-111.
-
(1993)
BioEssays
, vol.15
, pp. 105-111
-
-
Blasi, F.1
-
48
-
-
0031902286
-
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization
-
Bajou K, Noel A, Gerard RD, et al. Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization. Nature Med 1998; 4: 923-928.
-
(1998)
Nature Med
, vol.4
, pp. 923-928
-
-
Bajou, K.1
Noel, A.2
Gerard, R.D.3
-
49
-
-
0027742907
-
Epithelioid sarcoma: A clinicopathologic and prognostic study of 26 cases
-
Evans HL, Baer SC. Epithelioid sarcoma: a clinicopathologic and prognostic study of 26 cases. Semin Diagn Pathol 1993; 10: 286-291.
-
(1993)
Semin Diagn Pathol
, vol.10
, pp. 286-291
-
-
Evans, H.L.1
Baer, S.C.2
-
50
-
-
0018828154
-
Spindle cell squamous carcinomas and sarcoma-like tumors of the skin: A comparative study of 38 cases
-
Evans HL, Smith JL. Spindle cell squamous carcinomas and sarcoma-like tumors of the skin: a comparative study of 38 cases. Cancer 1980; 45: 2687-2697.
-
(1980)
Cancer
, vol.45
, pp. 2687-2697
-
-
Evans, H.L.1
Smith, J.L.2
-
51
-
-
0017178366
-
Spindle cell carcinoma: Ultrastructural evidence of squamous origin and collagen production by the tumor cells
-
Battifora H. Spindle cell carcinoma: ultrastructural evidence of squamous origin and collagen production by the tumor cells. Cancer 1976; 37: 2275-2282.
-
(1976)
Cancer
, vol.37
, pp. 2275-2282
-
-
Battifora, H.1
-
52
-
-
0031304272
-
Met-HGF/SF: Tumorigenesis, invasion and metastasis
-
Vande Woude G, Jeffers M, Cortner J, Alvord G, Tsarfaty I, Resau J. Met-HGF/SF: tumorigenesis, invasion and metastasis. Ciba Found Symp 1997; 212: 119-130.
-
(1997)
Ciba Found Symp
, vol.212
, pp. 119-130
-
-
Vande Woude, G.1
Jeffers, M.2
Cortner, J.3
Alvord, G.4
Tsarfaty, I.5
Resau, J.6
-
53
-
-
0027269685
-
Exon skipping in the E-cadherin gene transcript in metastatic human gastric carcinomas
-
Becker KF, Atkinson MJ, Reich U, Huang HH, Siewart JR, Hofler H. Exon skipping in the E-cadherin gene transcript in metastatic human gastric carcinomas. Hum Mol Genet 1993; 2: 803-804.
-
(1993)
Hum Mol Genet
, vol.2
, pp. 803-804
-
-
Becker, K.F.1
Atkinson, M.J.2
Reich, U.3
Huang, H.H.4
Siewart, J.R.5
Hofler, H.6
-
54
-
-
0027977943
-
E-cadherin gene mutations provide clues to diffuse type gastric carcinomas
-
Becker KF, Atkinson MJ, Reich U, et al. E-cadherin gene mutations provide clues to diffuse type gastric carcinomas. Cancer Res 1994; 54: 3845-3852.
-
(1994)
Cancer Res
, vol.54
, pp. 3845-3852
-
-
Becker, K.F.1
Atkinson, M.J.2
Reich, U.3
-
55
-
-
0028208313
-
E-cadherin gene mutations in human gastric carcinoma cell lines
-
Oda T, Kanai Y, Oyama T, et al. E-cadherin gene mutations in human gastric carcinoma cell lines. Proc Natl Acad Sci USA 1994; 91: 1858-1862.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1858-1862
-
-
Oda, T.1
Kanai, Y.2
Oyama, T.3
-
56
-
-
0028100547
-
Mutations of the E-cadherin gene in human gynecologic cancers
-
Risinger J, Berchuck A, Kohler M, Boyd J. Mutations of the E-cadherin gene in human gynecologic cancers. Nature Genet 1994; 7: 98-102.
-
(1994)
Nature Genet
, vol.7
, pp. 98-102
-
-
Risinger, J.1
Berchuck, A.2
Kohler, M.3
Boyd, J.4
-
57
-
-
0027507028
-
Loss of epithelial differentiation and gain of invasiveness correlate with tyrosine phosphorylation of the E-cadherin/β-catenin complex in cells transformed with a temperature-sensitive v-SRC gene
-
Behrens J, Vakaet L, Friis R, et al. Loss of epithelial differentiation and gain of invasiveness correlate with tyrosine phosphorylation of the E-cadherin/β-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J Cell Biol 1993; 120: 757-766.
-
(1993)
J Cell Biol
, vol.120
, pp. 757-766
-
-
Behrens, J.1
Vakaet, L.2
Friis, R.3
-
58
-
-
0027459346
-
p60 causes tyrosine phosphorylation and inactivation of the N-cadherin catenin cell adhesion system
-
Hamaguchi M, Matsuyoshi N, Ohnishi Y, Goloh B, Takeichi M, Nagai Y. p60 causes tyrosine phosphorylation and inactivation of the N-cadherin catenin cell adhesion system. EMBO J 1993; 12: 307-314.
-
(1993)
EMBO J
, vol.12
, pp. 307-314
-
-
Hamaguchi, M.1
Matsuyoshi, N.2
Ohnishi, Y.3
Goloh, B.4
Takeichi, M.5
Nagai, Y.6
-
59
-
-
0012148048
-
Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases
-
Hirst RA, Horwitz A, Buck C, Rohrschneider L. Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases. Proc Natl Acad Sci USA 1986; 83: 6470-6474.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 6470-6474
-
-
Hirst, R.A.1
Horwitz, A.2
Buck, C.3
Rohrschneider, L.4
-
60
-
-
0028808131
-
Deletion and altered regulation of p16INK4a and p15INK4b in undifferentiated mouse skin tumors
-
Emardopoulos S, Street AJ, Quelle DE, et al. Deletion and altered regulation of p16INK4a and p15INK4b in undifferentiated mouse skin tumors. Cancer Res 1995; 55: 5168-5172.
-
(1995)
Cancer Res
, vol.55
, pp. 5168-5172
-
-
Emardopoulos, S.1
Street, A.J.2
Quelle, D.E.3
-
61
-
-
0026385870
-
Progression of squamous carcinoma cells to spindle carcinoma of the mouse skin is associated with an imbalance of H-ras alleles on chromosome 7
-
Buchmann A, Ruggeri B, Klein-Szanto AJP, Balmain A. Progression of squamous carcinoma cells to spindle carcinoma of the mouse skin is associated with an imbalance of H-ras alleles on chromosome 7. Cancer Res 1991; 51: 4097-4101.
-
(1991)
Cancer Res
, vol.51
, pp. 4097-4101
-
-
Buchmann, A.1
Ruggeri, B.2
Klein-Szanto, A.J.P.3
Balmain, A.4
-
62
-
-
0028168242
-
INK4B is a potential effector of TGF-β-induced cell cycle arrest
-
INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 1994; 371: 257-261.
-
(1994)
Nature
, vol.371
, pp. 257-261
-
-
Hannon, G.J.1
Beach, D.2
-
64
-
-
0031817391
-
Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: Implications for tumor invasion
-
Portella G, Cumming SA, Liddell J, et al. Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion. Cell Growth Differ 1998; 9: 393-404.
-
(1998)
Cell Growth Differ
, vol.9
, pp. 393-404
-
-
Portella, G.1
Cumming, S.A.2
Liddell, J.3
-
65
-
-
0029662049
-
TGF-β1 and Ha-ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
-
Oft M, Peli J, Rudaz C, Schwarz H, Beug H, Reichmann E. TGF-β1 and Ha-ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev 1996; 10: 2462-2477.
-
(1996)
Genes Dev
, vol.10
, pp. 2462-2477
-
-
Oft, M.1
Peli, J.2
Rudaz, C.3
Schwarz, H.4
Beug, H.5
Reichmann, E.6
-
66
-
-
0028603343
-
TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors
-
Miettinen PJ, Ebner R, Lopez AR, Derynck R. TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors. J Cell Biol 1994; 127: 2021-2036.
-
(1994)
J Cell Biol
, vol.127
, pp. 2021-2036
-
-
Miettinen, P.J.1
Ebner, R.2
Lopez, A.R.3
Derynck, R.4
-
67
-
-
0029101527
-
Chronic exposure of cultured transfected mouse epidermal cells to TGFβ1 induces an epithelial mesenchymal transdiffcrentiation and a spindle tumoral phenotype
-
Caulin C, Scholl SG, Frontelo P, GamalloC, Quintanilla M. Chronic exposure of cultured transfected mouse epidermal cells to TGFβ1 induces an epithelial mesenchymal transdiffcrentiation and a spindle tumoral phenotype. Cell Growth Differ 1995; 6: 1027-1035.
-
(1995)
Cell Growth Differ
, vol.6
, pp. 1027-1035
-
-
Caulin, C.1
Scholl, S.G.2
Frontelo, P.3
Quintanilla, M.4
-
68
-
-
0022373618
-
Human transforming growth factor-beta cDNA sequence and expression in tumor cell lines
-
Derynck R, Jarrett JA, Chen EY, et al. Human transforming growth factor-beta cDNA sequence and expression in tumor cell lines. Nature 1985; 316: 701-705.
-
(1985)
Nature
, vol.316
, pp. 701-705
-
-
Derynck, R.1
Jarrett, J.A.2
Chen, E.Y.3
-
69
-
-
0028142208
-
Transforming growth factor beta 1 expression in benign and malignant prostatic tumors
-
Glynne-Jones E, Harper ME, Goddard L, Eaton CL, Matthews PN, Griffiths K. Transforming growth factor beta 1 expression in benign and malignant prostatic tumors. Prastate 1994; 25: 210-218.
-
(1994)
Prastate
, vol.25
, pp. 210-218
-
-
Glynne-Jones, E.1
Harper, M.E.2
Goddard, L.3
Eaton, C.L.4
Matthews, P.N.5
Griffiths, K.6
-
70
-
-
0027232566
-
Autocrine production of TGF-alpha and TGF-beta during tumour progression of rat oral keratinocytes
-
Donnelly MJ, Patel V, Yeudall WA, Game SM, Scully C, Prime SS. Autocrine production of TGF-alpha and TGF-beta during tumour progression of rat oral keratinocytes. Carcinogenesis 1993; 14: 981-985.
-
(1993)
Carcinogenesis
, vol.14
, pp. 981-985
-
-
Donnelly, M.J.1
Patel, V.2
Yeudall, W.A.3
Game, S.M.4
Scully, C.5
Prime, S.S.6
-
71
-
-
0025848971
-
TGF-beta 1 and skin carcinogenesis: Antiproliferative effect in vitro and TGF-beta 1 mRNA expression during epidermal hyperproliferation and multistage tumorigenesis
-
Krieg P, Schnapke R, Furstenberger G, Vogt I, Marks F. TGF-beta 1 and skin carcinogenesis: antiproliferative effect in vitro and TGF-beta 1 mRNA expression during epidermal hyperproliferation and multistage tumorigenesis. Mol Carcinog 1991; 4: 129-137.
-
(1991)
Mol Carcinog
, vol.4
, pp. 129-137
-
-
Krieg, P.1
Schnapke, R.2
Furstenberger, G.3
Vogt, I.4
Marks, F.5
-
72
-
-
0026656525
-
Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor βl
-
Arrick BA, Lopez AR, Elfman F, Ebner R, Damsky CH, Derynck R. Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor βl. J Cell Biol 1992; 118: 715-726.
-
(1992)
J Cell Biol
, vol.118
, pp. 715-726
-
-
Arrick, B.A.1
Lopez, A.R.2
Elfman, F.3
Ebner, R.4
Damsky, C.H.5
Derynck, R.6
-
73
-
-
0028251039
-
The tumor-promoting effect of wounding: A possible role for TGF-beta-induced stromal alterations
-
Sieweke MH, Bissell MJ. The tumor-promoting effect of wounding: a possible role for TGF-beta-induced stromal alterations. Crit Rev Oncog 1994; 5: 297-311.
-
(1994)
Crit Rev Oncog
, vol.5
, pp. 297-311
-
-
Sieweke, M.H.1
Bissell, M.J.2
-
75
-
-
0022471924
-
Transforming growth factor type beta: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro
-
Roberts AB, Sporn MB, Assoian RK, et al. Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA 1986; 83: 4167-4171.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 4167-4171
-
-
Roberts, A.B.1
Sporn, M.B.2
Assoian, R.K.3
-
76
-
-
11944255353
-
Transforming growth factor β stimulates mammary adenocarcinoma cell invasion and metastatic potential
-
Welch DR, Fabra A, Nakajima M. Transforming growth factor β stimulates mammary adenocarcinoma cell invasion and metastatic potential. Proc Natl Acal Sci USA 1990; 87: 7678-7682.
-
(1990)
Proc Natl Acal Sci USA
, vol.87
, pp. 7678-7682
-
-
Welch, D.R.1
Fabra, A.2
Nakajima, M.3
-
77
-
-
0027137485
-
Anti-transforming growth factor (TGF)-β antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer activity
-
Arteaga C, Hurd SD, Winnier AR, Johnson MD, Fendly BM, Forbes JT. Anti-transforming growth factor (TGF)-β antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer activity. J Clin Invest 1993; 92: 2569-2576.
-
(1993)
J Clin Invest
, vol.92
, pp. 2569-2576
-
-
Arteaga, C.1
Hurd, S.D.2
Winnier, A.R.3
Johnson, M.D.4
Fendly, B.M.5
Forbes, J.T.6
-
78
-
-
0000201238
-
Growth factors from murine sarcoma virus-transformed cells
-
De Larco JE, Todaro GJ. Growth factors from murine sarcoma virus-transformed cells. Proc Natl Acad Sci USA 1978; 75: 4001-4005.
-
(1978)
Proc Natl Acad Sci USA
, vol.75
, pp. 4001-4005
-
-
De Larco, J.E.1
Todaro, G.J.2
-
79
-
-
0020472387
-
Isolation from murine sarcoma cells of novel transforming growth factors potentiated by EGF
-
Roberts AB, Anzano MA, Lamb LC, et al. Isolation from murine sarcoma cells of novel transforming growth factors potentiated by EGF. Nature 1982; 295: 417-419.
-
(1982)
Nature
, vol.295
, pp. 417-419
-
-
Roberts, A.B.1
Anzano, M.A.2
Lamb, L.C.3
-
80
-
-
0023874730
-
Localized production of TGF-beta mRNA in tumour promoter-stimulated mouse epidermis
-
Akhurst RJ, Fee F, Balmain A. Localized production of TGF-beta mRNA in tumour promoter-stimulated mouse epidermis. Nature 1988; 331: 363-365.
-
(1988)
Nature
, vol.331
, pp. 363-365
-
-
Akhurst, R.J.1
Fee, F.2
Balmain, A.3
-
81
-
-
0028986244
-
Concerted action of TGFβ1 and its type II receptor in control of epidermal homeostasis in transgenic mice
-
Cui W, Fowlis DJ, Cousins FM, et al. Concerted action of TGFβ1 and its type II receptor in control of epidermal homeostasis in transgenic mice. Genes Dev 1995; 9: 945-955
-
(1995)
Genes Dev
, vol.9
, pp. 945-955
-
-
Cui, W.1
Fowlis, D.J.2
Cousins, F.M.3
-
82
-
-
0029153609
-
Kip/Cip and Ink4 cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β
-
Reynisdottir I, Polyak K, Iavarone A, Massagué J. Kip/Cip and Ink4 cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev 1995; 9: 1831-1845.
-
(1995)
Genes Dev
, vol.9
, pp. 1831-1845
-
-
Reynisdottir, I.1
Polyak, K.2
Iavarone, A.3
Massagué, J.4
-
83
-
-
0030614715
-
The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2
-
Reynisdottir I, Massague J. The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2. Genes Der 1997; 11: 492-503.
-
(1997)
Genes Der
, vol.11
, pp. 492-503
-
-
Reynisdottir, I.1
Massague, J.2
-
84
-
-
0030257584
-
p53-dependent repression of cdk4 synthesis in transforming growth factor-beta-induced G1 cell cycle arrest
-
Ewen ME. p53-dependent repression of cdk4 synthesis in transforming growth factor-beta-induced G1 cell cycle arrest. J Lab Clin Med 1996; 128: 355-360.
-
(1996)
J Lab Clin Med
, vol.128
, pp. 355-360
-
-
Ewen, M.E.1
-
85
-
-
0028981277
-
p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest
-
Ewen ME, Oliver CJ, Sluss HK, Miller SJ, Peeper DS. p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest. Genes Dev 1995; 9: 204-217.
-
(1995)
Genes Dev
, vol.9
, pp. 204-217
-
-
Ewen, M.E.1
Oliver, C.J.2
Sluss, H.K.3
Miller, S.J.4
Peeper, D.S.5
-
86
-
-
0027374766
-
TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest
-
Ewen ME, Sluss HK, Whitehouse LL, Livingston DM. TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell 1993; 74: 1009-1020.
-
(1993)
Cell
, vol.74
, pp. 1009-1020
-
-
Ewen, M.E.1
Sluss, H.K.2
Whitehouse, L.L.3
Livingston, D.M.4
-
87
-
-
0027288908
-
Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4
-
Kato J, Matsushime H, Hiebert SW, Ewen ME, Sherr CJ. Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev 1993; 7: 331-342.
-
(1993)
Genes Dev
, vol.7
, pp. 331-342
-
-
Kato, J.1
Matsushime, H.2
Hiebert, S.W.3
Ewen, M.E.4
Sherr, C.J.5
-
88
-
-
0030978315
-
Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15
-
Iavarone A, Massague J. Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15. Nature 1997; 387: 417-422.
-
(1997)
Nature
, vol.387
, pp. 417-422
-
-
Iavarone, A.1
Massague, J.2
-
89
-
-
0031438047
-
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
-
Heldin CH, Miyazono K, ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 1997; 390: 465-471.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Dijke, P.3
-
90
-
-
0031863899
-
TGF-beta signaling, Smads, and tumor suppressors
-
Padgett RW, Das P, Krishna S. TGF-beta signaling, Smads, and tumor suppressors. BioEssays 1998; 20: 382-390.
-
(1998)
BioEssays
, vol.20
, pp. 382-390
-
-
Padgett, R.W.1
Das, P.2
Krishna, S.3
-
91
-
-
0031911356
-
SMADs: Mediators and regulators of TGF-beta signaling
-
Kretzschmar M, Massague J. SMADs: mediators and regulators of TGF-beta signaling. Curr Opin Genet Dev 1998; 8: 103-111.
-
(1998)
Curr Opin Genet Dev
, vol.8
, pp. 103-111
-
-
Kretzschmar, M.1
Massague, J.2
-
92
-
-
0032110707
-
Characterization of human FAST-1, a TGF beta and activin signal transducer
-
Zhou S, Zawel L, Lengauer C, Kinzler KW, Vogelstein B. Characterization of human FAST-1, a TGF beta and activin signal transducer. Mol Cell 1998; 2: 121-127.
-
(1998)
Mol Cell
, vol.2
, pp. 121-127
-
-
Zhou, S.1
Zawel, L.2
Lengauer, C.3
Kinzler, K.W.4
Vogelstein, B.5
-
93
-
-
0032110463
-
Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2
-
Labbe E, Silvestri C, Hoodless PA, Wrana JL, Attisano L. Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2. Mol Cell 1998; 2: 109-120.
-
(1998)
Mol Cell
, vol.2
, pp. 109-120
-
-
Labbe, E.1
Silvestri, C.2
Hoodless, P.A.3
Wrana, J.L.4
Attisano, L.5
-
94
-
-
0028826107
-
Mutations of the transforming growth factor-beta type II receptor gene and genomic instability in hereditary nonpolyposis colorectal cancer
-
Lu SL, Akiyama Y, Nagasaki H, Saitoh K, Yuasa Y. Mutations of the transforming growth factor-beta type II receptor gene and genomic instability in hereditary nonpolyposis colorectal cancer. Biochem Biophys Res Commun 1995; 216: 452-457.
-
(1995)
Biochem Biophys Res Commun
, vol.216
, pp. 452-457
-
-
Lu, S.L.1
Akiyama, Y.2
Nagasaki, H.3
Saitoh, K.4
Yuasa, Y.5
-
95
-
-
0029066689
-
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
-
Markowitz S, Wang J, Myeroff L, et al. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science 1995; 268: 1336-1338.
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
Wang, J.2
Myeroff, L.3
-
96
-
-
0031976330
-
Mutation of the transforming growth factor-beta type II receptor gene is a rare event in human sporadic gastric carcinomas
-
Shitara Y, Yokozaki H, Yasui W, Takenoshita S, Nagamachi Y, Tahara E. Mutation of the transforming growth factor-beta type II receptor gene is a rare event in human sporadic gastric carcinomas. Int J Oncol 1998; 12: 1061-1065.
-
(1998)
Int J Oncol
, vol.12
, pp. 1061-1065
-
-
Shitara, Y.1
Yokozaki, H.2
Yasui, W.3
Takenoshita, S.4
Nagamachi, Y.5
Tahara, E.6
-
97
-
-
16044369574
-
MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
-
Eppert K, Scherer SW, Ozcelik H, et al. MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 1996; 86: 543-552.
-
(1996)
Cell
, vol.86
, pp. 543-552
-
-
Eppert, K.1
Scherer, S.W.2
Ozcelik, H.3
-
98
-
-
0030593038
-
DPC4, a candidate tumour suppressor gene at human chromosome 18q21.1
-
Hahn SA, Schutte M, Shamsul Hoque ATM, et al. DPC4, a candidate tumour suppressor gene at human chromosome 18q21.1. Science 1996; 271: 350-353.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Shamsul Hoque, A.T.M.3
-
99
-
-
0030848192
-
Frequency of Smad gene mutations in human cancers
-
Riggins GJ. Frequency of Smad gene mutations in human cancers. Cancer Res 1997; 57: 2578-2580.
-
(1997)
Cancer Res
, vol.57
, pp. 2578-2580
-
-
Riggins, G.J.1
-
100
-
-
9344223357
-
DPC4 gene in various tumor types
-
Schutte M. DPC4 gene in various tumor types. Cancer Res 1996; 56: 2527-2530.
-
(1996)
Cancer Res
, vol.56
, pp. 2527-2530
-
-
Schutte, M.1
-
101
-
-
0032498328
-
Genomic structure of the human Smad3 gene and its infrequent alterations in colorectal cancers
-
Arai T, Akiyama Y, Okabe S, Ando M, Endo M, Yuasa Y. Genomic structure of the human Smad3 gene and its infrequent alterations in colorectal cancers. Cancer Lett 1998; 122: 157-163.
-
(1998)
Cancer Lett
, vol.122
, pp. 157-163
-
-
Arai, T.1
Akiyama, Y.2
Okabe, S.3
Ando, M.4
Endo, M.5
Yuasa, Y.6
-
102
-
-
0032545944
-
hSmad5 gene, a human hsmad family member: Its full length cDNA, genomic structure, promoter region and mutation analysis in human tumors
-
Gemma A, Hagiwara K, Vincent F, et al. hSmad5 gene, a human hSmad family member: its full length cDNA, genomic structure, promoter region and mutation analysis in human tumors. Oncogene 1998; 16: 951-956.
-
(1998)
Oncogene
, vol.16
, pp. 951-956
-
-
Gemma, A.1
Hagiwara, K.2
Vincent, F.3
-
103
-
-
0032489508
-
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
-
Takaku K, Oshima M, Miyoshi H, Matsui M, Seldin MF, Taketo MM. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell 1998; 92: 645-656.
-
(1998)
Cell
, vol.92
, pp. 645-656
-
-
Takaku, K.1
Oshima, M.2
Miyoshi, H.3
Matsui, M.4
Seldin, M.F.5
Taketo, M.M.6
-
104
-
-
0032524069
-
Mutations in the SMAD4/DPC4 gene in juvenile polyposis
-
Howe JR, Roth S, Ringold JC, et al. Mutations in the SMAD4/DPC4 gene in juvenile polyposis. Science 1998; 280: 1086-1088.
-
(1998)
Science
, vol.280
, pp. 1086-1088
-
-
Howe, J.R.1
Roth, S.2
Ringold, J.C.3
-
105
-
-
0032500010
-
Expression of a dominant negative type II TGF-beta receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development
-
Amendt C, Schirmacher P, Weber H, Blessing M. Expression of a dominant negative type II TGF-beta receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development. Oncogene 1998; 17: 25-34.
-
(1998)
Oncogene
, vol.17
, pp. 25-34
-
-
Amendt, C.1
Schirmacher, P.2
Weber, H.3
Blessing, M.4
-
106
-
-
0031441041
-
Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene
-
Bottinger EP, Jakubczak JL, Haines DC, Bagnall K, Wakefield LM. Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene. Cancer Res 1997; 57: 5564-5570.
-
(1997)
Cancer Res
, vol.57
, pp. 5564-5570
-
-
Bottinger, E.P.1
Jakubczak, J.L.2
Haines, D.C.3
Bagnall, K.4
Wakefield, L.M.5
-
107
-
-
0030598681
-
TGFβ1 inhibits the formation of benign skin tumours but enhances progression to invasive spindle cell carcinomas in transgenic mice
-
Cui W, Fowlis DJ, Bryson S. et al. TGFβ1 inhibits the formation of benign skin tumours but enhances progression to invasive spindle cell carcinomas in transgenic mice. Cell 1996; 86: 531-542.
-
(1996)
Cell
, vol.86
, pp. 531-542
-
-
Cui, W.1
Fowlis, D.J.2
Bryson, S.3
-
108
-
-
2642614530
-
Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency
-
Tang B, Bottinger EP, Jakowlew SB, et al. Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency. Nature Med 1998; 4: 802-807.
-
(1998)
Nature Med
, vol.4
, pp. 802-807
-
-
Tang, B.1
Bottinger, E.P.2
Jakowlew, S.B.3
-
109
-
-
0029802491
-
Altered epidermal growth control in vivo in transgenic mice expressing TGFbeta1 from an inducible keratin gene promoter
-
Fowlis DJ, Cui W, Johnson SA, Balmain A, Akhurst RJ. Altered epidermal growth control in vivo in transgenic mice expressing TGFbeta1 from an inducible keratin gene promoter. Cell Growth Diff 1996; 7: 679-687.
-
(1996)
Cell Growth Diff
, vol.7
, pp. 679-687
-
-
Fowlis, D.J.1
Cui, W.2
Johnson, S.A.3
Balmain, A.4
Akhurst, R.J.5
-
110
-
-
0030953639
-
Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition
-
Wang XJ, Greenhalgh DA, Bickenbach JR, et al. Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition. Proc Natl Acad Sci USA 1997; 94: 2386-2391.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2386-2391
-
-
Wang, X.J.1
Greenhalgh, D.A.2
Bickenbach, J.R.3
-
111
-
-
85101729959
-
Smad3 mutant mice develop metastatic colorectal cancer
-
Zhu Y, Richardson JA, Parada LF, Fraff JM. Smad3 mutant mice develop metastatic colorectal cancer. Cell 1998; 94: 1-20.
-
(1998)
Cell
, vol.94
, pp. 1-20
-
-
Zhu, Y.1
Richardson, J.A.2
Parada, L.F.3
Fraff, J.M.4
-
112
-
-
0027217314
-
Loss of expression of transforming growth factor β in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion
-
Glick AB, Kulkarni AB, Tennenbaum T, et al. Loss of expression of transforming growth factor β in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion. Proc Natl Acad Sci USA 1993; 90: 6076-6080.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6076-6080
-
-
Glick, A.B.1
Kulkarni, A.B.2
Tennenbaum, T.3
-
113
-
-
0025914188
-
Loss of growth control by tGFβ occurs at a late stage of mouse carcinogenesis and is independent of ras gene activation
-
Haddow S, Fowlis DJ, Parkinson K, Akhurst RJ, Balmain A. Loss of growth control by TGFβ occurs at a late stage of mouse carcinogenesis and is independent of ras gene activation. Oncogene 1991; 6: 1465-1470.
-
(1991)
Oncogene
, vol.6
, pp. 1465-1470
-
-
Haddow, S.1
Fowlis, D.J.2
Parkinson, K.3
Akhurst, R.J.4
Balmain, A.5
-
114
-
-
0027538329
-
Growth inhibition of human pancreatic carcinoma cells by transforming growth factor beta-1
-
Baldwin RL, Korc M. Growth inhibition of human pancreatic carcinoma cells by transforming growth factor beta-1. Growth Factors 1993; 8: 23-34.
-
(1993)
Growth Factors
, vol.8
, pp. 23-34
-
-
Baldwin, R.L.1
Korc, M.2
-
115
-
-
0024346237
-
Lack of correlation between sensitivity to growth inhibition and receptor number of transforming growth factor beta in human squamous carcinoma cell lines
-
Hebert CD, Birnbaum LS. Lack of correlation between sensitivity to growth inhibition and receptor number of transforming growth factor beta in human squamous carcinoma cell lines. Cancer Res 1989; 49: 3196-3202.
-
(1989)
Cancer Res
, vol.49
, pp. 3196-3202
-
-
Hebert, C.D.1
Birnbaum, L.S.2
-
116
-
-
0028171315
-
Transforming growth factor-beta 1 induces growth inhibition of a human medullary thyroid carcinoma cell line despite an increase in steady state c-myc messenger ribonucleic acid levels
-
Khosla S, Oursler MJ, Schroeder MJ, Eberhardt NL. Transforming growth factor-beta 1 induces growth inhibition of a human medullary thyroid carcinoma cell line despite an increase in steady state c-myc messenger ribonucleic acid levels. Endocrinology 1994; 135: 1887-1893.
-
(1994)
Endocrinology
, vol.135
, pp. 1887-1893
-
-
Khosla, S.1
Oursler, M.J.2
Schroeder, M.J.3
Eberhardt, N.L.4
-
117
-
-
10244232854
-
Sensitivity to transforming growth factor beta 1-induced growth arrest is common in human squamous cell carcinoma cell lines: C-MYC down-regulation and p21wafl induction are important early events
-
Malliri A, Yeudall WA, Nikolic M, Crouch DH, Parkinson EK, Ozanne B. Sensitivity to transforming growth factor beta 1-induced growth arrest is common in human squamous cell carcinoma cell lines: c-MYC down-regulation and p21wafl induction are important early events. Cell Growth Differ 1996; 7: 1291-1304.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 1291-1304
-
-
Malliri, A.1
Yeudall, W.A.2
Nikolic, M.3
Crouch, D.H.4
Parkinson, E.K.5
Ozanne, B.6
-
118
-
-
0028871322
-
Effects of transforming growth factor beta-1 on growth-regulatory genes in tumour-derived human oral keratinocytes
-
Paterson IC, Patel V, Sandy JR, Prime SS, Yeudall WA. Effects of transforming growth factor beta-1 on growth-regulatory genes in tumour-derived human oral keratinocytes. Br J Cancer 1995; 72: 922-927.
-
(1995)
Br J Cancer
, vol.72
, pp. 922-927
-
-
Paterson, I.C.1
Patel, V.2
Sandy, J.R.3
Prime, S.S.4
Yeudall, W.A.5
-
119
-
-
0028988230
-
Effects of TGF-beta 1 (transforming growth factor-beta 1) on the cell cycle regulation of human breast adenocarcinoma (MCF-7) cells
-
Mazars P, Barboule N, Baldin V, Vidal S, Ducommun B, Valette A. Effects of TGF-beta 1 (transforming growth factor-beta 1) on the cell cycle regulation of human breast adenocarcinoma (MCF-7) cells. FEBS Lett 1995; 362: 295-300.
-
(1995)
FEBS Lett
, vol.362
, pp. 295-300
-
-
Mazars, P.1
Barboule, N.2
Baldin, V.3
Vidal, S.4
Ducommun, B.5
Valette, A.6
-
120
-
-
0026785290
-
Inhibition of growth by transforming growth factor-β following fusion of two non-responsive human carcinoma cell lines
-
Geiser AG, Burmester JK, Webbink R, Roberts AB, Sporn MB. Inhibition of growth by transforming growth factor-β following fusion of two non-responsive human carcinoma cell lines. J Biol Chem 1992; 267: 2588-2593.
-
(1992)
J Biol Chem
, vol.267
, pp. 2588-2593
-
-
Geiser, A.G.1
Burmester, J.K.2
Webbink, R.3
Roberts, A.B.4
Sporn, M.B.5
-
121
-
-
0029033910
-
Independent changes in type 1 and type II receptors for transforming growth factor β induced by bone morphogenetic protein 2 parallel expression of the osteoblast phenotype
-
Centrella M, Casinghino S, Kim J, et al. Independent changes in type 1 and type II receptors for transforming growth factor β induced by bone morphogenetic protein 2 parallel expression of the osteoblast phenotype. Mol Cell Biol 1995; 15: 3273-3281.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3273-3281
-
-
Centrella, M.1
Casinghino, S.2
Kim, J.3
-
122
-
-
0032524323
-
The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors
-
Dyson S, Gurdon JB. The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors. Cell 1998; 93: 557-568.
-
(1998)
Cell
, vol.93
, pp. 557-568
-
-
Dyson, S.1
Gurdon, J.B.2
-
123
-
-
0029991682
-
Microsatellite instability and the role of hMSH2 in sporadic colorectal cancer
-
Bubb VJ, Curtis LJ, Cunningham C, et al. Microsatellite instability and the role of hMSH2 in sporadic colorectal cancer. Oncogene 1996; 12: 2641-2649.
-
(1996)
Oncogene
, vol.12
, pp. 2641-2649
-
-
Bubb, V.J.1
Curtis, L.J.2
Cunningham, C.3
-
124
-
-
2642605344
-
Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases
-
de Caestecker MP, Parks WT, Frank CJ, et al. Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases. Genes Dev 1998; 12: 1587-1592.
-
(1998)
Genes Dev
, vol.12
, pp. 1587-1592
-
-
De Caestecker, M.P.1
Parks, W.T.2
Frank, C.J.3
-
125
-
-
0026612306
-
Activation of p21-ras by transforming growth factor beta in epithelial cells
-
Mulder KM, Morris SL. Activation of p21-ras by transforming growth factor beta in epithelial cells. J Biol Chem 1992; 267: 5029-5011.
-
(1992)
J Biol Chem
, vol.267
, pp. 5029-15011
-
-
Mulder, K.M.1
Morris, S.L.2
-
126
-
-
0029788015
-
Altered transforming growth factor signaling in epithelial cells when ras activation is blocked
-
Hartsough MT, Frey RS, Zipfel PA, et al. Altered transforming growth factor signaling in epithelial cells when ras activation is blocked. J Biol Chem 1996; 271: 22368-22375.
-
(1996)
J Biol Chem
, vol.271
, pp. 22368-22375
-
-
Hartsough, M.T.1
Frey, R.S.2
Zipfel, P.A.3
-
127
-
-
0032499802
-
Blockade of TGFbeta3 up-regulation of p27Kip1 and p21Cip1 by expression of RasN17 in epithelial cells
-
Yue J, Buard A, Mulder KM. Blockade of TGFbeta3 up-regulation of p27Kip1 and p21Cip1 by expression of RasN17 in epithelial cells. Oncogene 1998; 17: 47-55.
-
(1998)
Oncogene
, vol.17
, pp. 47-55
-
-
Yue, J.1
Buard, A.2
Mulder, K.M.3
-
128
-
-
0029551805
-
Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction
-
Yamaguchi K, Shirakabe K, Shibuya H, et al. Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science 1995; 270: 2008-2011.
-
(1995)
Science
, vol.270
, pp. 2008-2011
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuya, H.3
-
129
-
-
0029940355
-
TAB1: An activator of the TAK1 MAPKKK in TGF-beta signal transduction
-
Shibuya H, Yamaguchi K, Shirakabe K, et al. TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. Science 1996; 272: 1179-1182.
-
(1996)
Science
, vol.272
, pp. 1179-1182
-
-
Shibuya, H.1
Yamaguchi, K.2
Shirakabe, K.3
-
130
-
-
0032498499
-
Molecular cloning of human TAK1 and its mutational analysis in human lung cancer
-
Kondo M, Osada H, Uchida K, et al. Molecular cloning of human TAK1 and its mutational analysis in human lung cancer. Int J Cancer 1998; 75: 559-563.
-
(1998)
Int J Cancer
, vol.75
, pp. 559-563
-
-
Kondo, M.1
Osada, H.2
Uchida, K.3
-
131
-
-
0032572723
-
Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription
-
Zhang Y, Feng XH, Derynck R. Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription. Nature 1998; 394: 909-913.
-
(1998)
Nature
, vol.394
, pp. 909-913
-
-
Zhang, Y.1
Feng, X.H.2
Derynck, R.3
-
132
-
-
0031053311
-
AP-1-mediated invasion requires increased expression of the hyaluronan receptor CD44
-
Lamb RF, Hennigan RF, Turnbull K, et al. AP-1-mediated invasion requires increased expression of the hyaluronan receptor CD44. Mol Cell Biol 1997; 17: 963-976.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 963-976
-
-
Lamb, R.F.1
Hennigan, R.F.2
Turnbull, K.3
-
133
-
-
0030390037
-
Oncogene-initiated aberrant signaling engenders the metastatic phenotype: Synergistic transcription factor interactions are targets for cancer therapy
-
Denhardt DT. Oncogene-initiated aberrant signaling engenders the metastatic phenotype: synergistic transcription factor interactions are targets for cancer therapy. Crit Rev Oncog 1996; 7: 261-291.
-
(1996)
Crit Rev Oncog
, vol.7
, pp. 261-291
-
-
Denhardt, D.T.1
-
134
-
-
0031970570
-
Activation of tissue-factor gene expression in breast carcinoma cells by stimulation of the RAF-ERK signaling pathway
-
Zhou JN, Ljungdahl S, Shoshan MC, Swedenborg J, Linder S. Activation of tissue-factor gene expression in breast carcinoma cells by stimulation of the RAF-ERK signaling pathway. Mol Carcinog 1998; 21: 234-243.
-
(1998)
Mol Carcinog
, vol.21
, pp. 234-243
-
-
Zhou, J.N.1
Ljungdahl, S.2
Shoshan, M.C.3
Swedenborg, J.4
Linder, S.5
-
135
-
-
0032528236
-
The tumor suppressor Smad4/DPC4 and transcnptional adaptor CBP/p300 are coactivators for Smad3 in TGF-beta-induced transcriptional activation
-
Feng XH, Zhang Y, Wu RY, Derynck R. The tumor suppressor Smad4/DPC4 and transcnptional adaptor CBP/p300 are coactivators for Smad3 in TGF-beta-induced transcriptional activation. Genes Dev 1998; 12: 2153-2163.
-
(1998)
Genes Dev
, vol.12
, pp. 2153-2163
-
-
Feng, X.H.1
Zhang, Y.2
Wu, R.Y.3
Derynck, R.4
-
136
-
-
0032483493
-
Physical and functional interaction of SMADs and p300/CBP
-
Pouponnot C, Jayaraman L, Massague J. Physical and functional interaction of SMADs and p300/CBP. J Biol Chem 1998; 273: 22865-22868.
-
(1998)
J Biol Chem
, vol.273
, pp. 22865-22868
-
-
Pouponnot, C.1
Jayaraman, L.2
Massague, J.3
-
137
-
-
0032527756
-
TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300
-
Janknecht R, Wells NJ, Hunter T. TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300. Genes Der 1998; 12: 2114-2119.
-
(1998)
Genes Der
, vol.12
, pp. 2114-2119
-
-
Janknecht, R.1
Wells, N.J.2
Hunter, T.3
-
138
-
-
0242587820
-
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
-
Kamei Y, Xu L, Heinzel T, et al. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 1996; 85: 403-414.
-
(1996)
Cell
, vol.85
, pp. 403-414
-
-
Kamei, Y.1
Xu, L.2
Heinzel, T.3
|