Lymphocyte traffic control by chemokines

Nature Immunology

Volumn 2, Issue 2, 2001, Pages 123-128

  Moser, Bernhard ^a   Loetscher, Pius ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR;

ANIMAL; HEMATOPOIESIS; HUMAN; IMMUNOLOGY; INFLAMMATION; LYMPHOCYTE; LYMPHOID TISSUE; METABOLISM; NEUTROPHIL CHEMOTAXIS; REVIEW; T LYMPHOCYTE;

ANIMALS; ANTIGENS; CHEMOKINES; CHEMOTAXIS, LEUKOCYTE; HEMATOPOIESIS; HUMANS; INFLAMMATION; LYMPHOCYTES; LYMPHOID TISSUE; RECEPTORS, CHEMOKINE; T-LYMPHOCYTES;

EID: 0035257205     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/84219     Document Type: Review

References (85)

1. Loetscher, P., Moser, B. & Baggiolini, M. Chemokines and their receptors in lymphocyte traffic and HIV infection. Adv. Immunol. 74, 127-180 (2000).
2. Zlotnik, A. & Yoshie, O. Chemokines: a new classification system and their role in Immunity. Immunity. 12, 121-127 (2000).
3. Murphy, P. M. et ol. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev. 52, 145-176 (2000).
4. Sallusto, F., Mackay, C. R. & Lanzavecchia, A.The role of chemokine receptors in primary, effector, and memory immune responses. Annu. Rev. Immunol. 18, 593-620 (2000).
5. von Andrian, U. H. & Mackay. C. R.T-cell function and migration.Two sides of the same coin. N. Engl. J. Med. 343, 1020-1034 (2000).
6. Cyster, J. G. Chemokines and cell migration in secondary lymphoid organs. Science 286, 2093-2102 (1999).
7. Campbell, J. J. & Butcher, E. C. Chemokines in tissue-specific and microenvironment-specific lymphocyte homing. Curr. Opin. Immunol. 12, 336-341 (2000).
8. Luther, S. A. & Cyster.J. G. Chemokines as regulators ofT cell differentiation. Nature Immunol. 2, 102-107 (2001).
9. Sanchez-Madrid, F. & del Pozo, M.A. Leukocyte polarization in cell migration and immune interactions. EMBO J. 18, 501-511 (1999).
10. Butcher, E. C.,Williams, M.,Youngman, K., Rott, L & Briskin, M. Lymphocyte trafficking and regional immunity. Adv. Immunol. 72, 209-253 (1999).
11. Murphy, P. M. Viral exploitation and subversion of the immune system through chemokine mimicry. Nature Immunol. 2, 116-122 (2001).
12. Rothenberg, M. E., MacLean, J. A., Pearlman, E., Luster,A. D. & Leder, P.Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia.J. Exp. Med. 185, 785-790 (1997).
13. Sherry, B., Horii, Y., Manogue, K. R.,Widmer, U. & Cerami,A. in Interleukin-8 (NAP-1) and Related Chemotoctic Cytokines Vol. 4. (eds Baggiolini, M. & Sorg, C.) 117-130 (Karger, Basel, 1992).
14. Nagasawa,T., Kikutani, H. & Kishimoto,T. Molecular cloning and structure of a pre-B-cell growth-stimulating factor. Proc. Natl Acad. Sci. USA 91, 2305-2309 (1994).
15. Kim, C. H. & Broxmeyer, H. E. Chemokines: signal lamps for trafficking of T and B cells for development and effector function. J. Leukoc. Biol. 65, 6-15 (1999).
16. Nagasawa, T. et al. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1.Nature 382, 635-638 (1996).
17. Zou,Y. R., Kottmann,A. H., Kuroda, M., Taniuchi, I. & Littman, D. R. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development Nature 393, 595-599 (1998).
18. Ma, Q. et at. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in C. Proc. Natl Acad. Sci. USA 95, 9448-9453 (1998).
19. Tachibana, K. et al. The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature 393, 591-594 (1998).
20. Nagasawa, T., Tachibana, K. & Kawabata, K.A CXC chemokine SDF-1/PBSF:a ligand for a HIV coreceptor. CXCR4. Adv. Immunol. 71, 211-228 (1999).
21. Peled, A. et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science 283, 845-848 (1999).
22. Ma, Q., Jones, D. & Springer, T.A. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. Immunity 10, 463-471 (1999).
23. Agace,W.W. et al. Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation. Curr. Biol. 10, 325-328 (2000).
24. Pablos, J. L. et al. Stromal-cell derived factor is expressed by dendritic cells and endothelium in human skin. Am. J. Pathol. 155, 1577-1586 (1999).
25. Chvatchko, Y. et at A key role for CC chemokine receptor 4 in lipopotysaccharide-induced endotoxic shock. J. Exp. Med. 191, 1755-1764 (2000).
26. Förster, R, et al. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99, 23-33 (1999).
27. Campbell, J. J., Pan, J. L. & Butcher, E. C. Developmental switches in chemokine responses during T cell maturation. J. Immunol. 163, 2353-2357 (1999).
28. Kim, C. H., Pelus, L. M., White, J. R. & Broxmeyer, H. E. Differential chemotactic behavior of developing T cells in response to thymic chemokines. Blood 91, 4434-4443 (1998).
29. Sallusto, F., Lenig, D., Förster, R., Lipp, M. & Lanzavecchia, A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401, 708-712 (1999).
30. H2 cell localization and delivery of B cell help in vivo. Science 286, 2159-2162 (1999).
31. +T cells provide help for B cell clonal expansion and antibody synthesis in a similar manner in vivo. J. Immunol 165, 3136-3144 (2000).
32. Gunn, M. D. et al. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J. Exp. Med. 189, 451-460 (1999).
33. Ngo,V. N. et al. Lymphotoxin α/β and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J. Exp. Med. 189, 403-412 (1999).
34. Legler, D. F. et al. B cell-attracting chemokine I, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLRI/CXCRS. J. Exp. Med. 187, 655-660 (1998).
35. Gunn, M. D. et al. A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. Nature 391.799-803 (1998).
36. Brandes, M., Legler, D. F., Sporri, B., Schaerli, P. & Moser, B.Activation-dependent modulation of B lymphocyte migration to chemokines. Int. Immunol. 12, 1285-1292 (2000).
37. Förster, R. et al. A putative chemokine receptor, BLRI, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87, 1037-1047 (1996).
38. Ansel, K. M. et al. A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 406, 309-314 (2000).
39. Schaerli, P. et all. CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function. J. Exp. Med. 192, 1553-1562 (2000).
40. Breitfeld, D. et at. Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles and support immunoglobulin production. J. Exp. Med. 192, 1545-1552 (2000).
41. Hutloff, A. et al. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature 397,263-266 (1999).
42. Swallow, M. M., Wallin, J. J. & Sha, W. C. B7h, a novel costimulatory homolog of B7. 1 and B7. 2, is induced by TNFα. Immunity. 11, 423-432 (1999).
43. Yoshinaga, S. K. et al. T-cell co-stimulation through B7RP-1 and ICOS. Nature 402, 827-532 (1999).
44. Mackay, C R. Follicular B-helper T cells and the Th1/Th2 paradigm. J. Exp. Med. 192, 31-34 (2000).
45. Warnock, R. A. et at The role of chemokines in the microenvironmental control of T versus B cell arrest in Peyer's patch high endothelial venules. J. Exp. Med. 191, 77-88 (2000).
46. Stein, J.V. et al. The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial venules. J. Exp. Med. 191, 61-76 (2000).
47. Campbell, J. J. et of. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science 279, 381-384 (1998).
48. Willimann, K. et al. The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activatedT cells via CCR7. Eur. J. Immunol. 28, 2025-2034 (1998).
49. Nagira, M. et al. A lymphocyte-specific CC chemokine, secondary lymphoid tissue chemokine (SLC), is a highly efficient chemoattractant for B cells and activated T cells. Eur. J. Immunol. 28, 1516-1523 (1998).
50. Cook, D. N. et al. CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue. Immunity. 12, 495-503 (2000).
51. Dieu, M. C. et al. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J. Exp. Med. 188, 373-386 (1998).
52. Liao, F. et al. CC-chemokine receptor 6 is expressed on diverse memory subsets of T cells and determines responsiveness to macrophage inflammatory protein 3α. J. Immunol. 162, 186-194 (1999).
53. Homey, B. et al. Cutting edge: the orphan chemokine receptor G protein-coupled receptor- 2 (GPR-2. CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC). J. Immunol. 164, 3465-3470 (2000).
54. Tang, H. L & Cyster,J. G. Chemokine up-regulation and activated T cell attraction by maturing dendritic cells. Science 284, 819-822 (1999).
55. Melchers, F., Rolink, A. G. & Schaniel, C.The role of chemokines in regulating cell migration during humoral immune responses. Cell 99, 351-354 (1999).
56. Sallusto, F., Lenig, D., Mackay, C. R. & Lanzavecchia, A. Flexible programs of chemokine receptor expression on human polarized T helper I and 2 lymphocytes. J. Exp. Med. 187, 875-583 (1998).
57. Bonecchi, R. et al. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (This) and Th2s. J. Exp. Med. 187, 129-134 (1998).
58. D'Ambrosio, D. et al. Selective up-regulation of chemokine receptors CCR4 and CCR8 upon activation of polarized human type 2Th cells. J. Immunol. 161, 5111-5115 (1998).
59. Bleul, C. C., Schultze, J. L. & Springer,T.A. B lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement. J. Exp. Med. 187, 753-762 (1998).
60. Adema, G. J. et al. A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. Nature 387, 713-717 (1997).
61. Baggiolini, M., Dewald, B. & Moser, B. Human chemokines: An update. Annu. Rev. Immunol. 15, 675-705 (1997).
62. Luster,A. D. Chemokines - Chemotactic cytokines that mediate inflammation. N. Engl. J. Med. 338, 436-445 (1998).
63. Mackay, C. R. Immunological memory. Adv. Immunol. 53, 217-265 (1993).
64. Morales, J. el al. CTACK, a skin-associated chemokine that preferentially attracts skin- homing memory T cells. Proc. Notl Acad. Sci. USA 96, 14470-14475 (1999).
65. Pan, J. et al. A novel chemokine ligand for CCR10 and CCR3 expressed by epithelial cells in mucosal tissues. J. Immunol. 165, 2943-2949 (2000).
66. Wang, W. et al. Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2). J. Biol. Chem. 275, 22313-22323 (2000).
67. Campbell, J. J. et al. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells. Nature 400, 776-780 (1999).
68. Zabel, B.A. et al. Human G protein-coupled receptor GPR-9-G/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis. J. Exp. Med. 190, 1241-1255 (1999).
69. Kunkel, E. J. et al. Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity. J. Exp. Med. 192,761-768 (2000).
70. Loetscher, R, Seitz, M., Baggiolini, M. & Moser, B. Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. J. Exp. Med. 184, 569-577 (1996).
71. Abbas,A. K., Murphy, K. M. & Sher,A. Functional diversity of helper T lymphocytes. Nature 383, 787-793 (1996).
72. Gutierrez-Ramos, J. C., Lloyd, C. & Gonzalo, J.A. Eotaxin: from an eosinophilic chemokine to a major regulator of allergic reactions. Immunol. Today 20, 500-504 (1999).
73. Sallusto, F., Mackay, C. R. &. Lanzavecchia, A. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 277, 2005-2007 (1997).
74. Gerber, B. O. et al. Functional expression of the eotaxin receptor CCR3 in T lymphocytes co- localizing with eosinophils. Curr. Biol. 7, 836-643 (1997).
75. Gutierrez-Ramos, J. C., Lloyd, C. & Gonzalo, J. A. Eotaxin: from an eosinophilic chemokine to a major regulator of allergic reactions. Immunol. Today 20, 500-504 (1999).
76. Loetscher, P. et al. CCR5 is characteristic of Th1 lymphocytes. Nature 391, 344-345 (1998).
77. Qin, S. X. et of. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J. Clin. Invest. 101, 746-754 (1998).
78. Mach, F. et al. Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells. J. Clin. Invest. 104, 1041-1050 (1999).
79. Sorensen, T. L. et al. Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J. Clin. Invest. 103, 807-815 (1999).
80. Pan, Y. et al. Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation. Nature 387, 611-617 (1997).
81. 3C motif. Nature 385, 640-644 (1997).
82. Matloubian, M., David,A., Engel, S., Ryan,J. E. & Cyster,J. G.A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nature Immunol. 1,298-304 (2000).
83. 3CR1, which mediates both leukocyte migration and adhesion. Cell 91, 521-530 (1997).
84. 3CR1 mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow. J. Exp. Med. 188, 1413-1419 (1998).
85. Loetscher, M. et of. TYMSTR, a putative chemokine receptor selectively expressed in activated T cells, exhibits HIV-1 coreceptor function. Curr. Biol. 7, 652-660 (1997).