-
2
-
-
0027237665
-
A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae
-
Baudin A., Ozier-Kalogeropoulos O., Denouel A., Lacroute F., Cullin C. A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae. Nucleic Acids Res. 21:1993;3329-3330.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 3329-3330
-
-
Baudin, A.1
Ozier-Kalogeropoulos, O.2
Denouel, A.3
Lacroute, F.4
Cullin, C.5
-
3
-
-
0035966394
-
Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40
-
Sonoda E., Morrison C., Yamashita Y.M., Takata M., Takeda S. Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 356:2001;111-117.
-
(2001)
Philos. Trans. R. Soc. Lond. B. Biol. Sci.
, vol.356
, pp. 111-117
-
-
Sonoda, E.1
Morrison, C.2
Yamashita, Y.M.3
Takata, M.4
Takeda, S.5
-
4
-
-
0036086941
-
The DT40 web site: Sampling and connecting the genes of a B cell line
-
Buerstedde J.M., Arakawa H., Watahiki A., Carninci P.P., Hayashizaki Y.Y., Korn B.et al. The DT40 web site: sampling and connecting the genes of a B cell line. Nucleic Acids Res. 30:2002;230-231.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 230-231
-
-
Buerstedde, J.M.1
Arakawa, H.2
Watahiki, A.3
Carninci, P.P.4
Hayashizaki, Y.Y.5
Korn, B.6
-
5
-
-
0033671090
-
Embryonic stem cells and gene targeting
-
Ledermann B. Embryonic stem cells and gene targeting. Exp. Physiol. 85:2000;603-613.
-
(2000)
Exp. Physiol.
, vol.85
, pp. 603-613
-
-
Ledermann, B.1
-
7
-
-
0033947611
-
Hammerhead ribozymes: Biochemical and chemical considerations
-
Goodchild J. Hammerhead ribozymes: biochemical and chemical considerations. Curr. Opin. Mol. Ther. 2:2000;272-281.
-
(2000)
Curr. Opin. Mol. Ther.
, vol.2
, pp. 272-281
-
-
Goodchild, J.1
-
8
-
-
0033741679
-
Antisense cancer therapy: The state of the science
-
Kushner D.M., Silverman R.H. Antisense cancer therapy: the state of the science. Curr. Oncol. Rep. 2:2000;23-30.
-
(2000)
Curr. Oncol. Rep.
, vol.2
, pp. 23-30
-
-
Kushner, D.M.1
Silverman, R.H.2
-
9
-
-
0037062951
-
RNA interference
-
Hannon G.J. RNA interference. Nature. 418:2002;244-251.
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
10
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., Mello C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 391:1998;806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
11
-
-
0034676448
-
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
-
Gonczy P., Echeverri C., Oegema K., Coulson A., Jones S.J., Copley R.R. et al. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature. 408:2000;331-336.
-
(2000)
Nature
, vol.408
, pp. 331-336
-
-
Gonczy, P.1
Echeverri, C.2
Oegema, K.3
Coulson, A.4
Jones, S.J.5
Copley, R.R.6
-
12
-
-
0034676457
-
Functional genomic analysis of C. elegans chromosome I by systematic RNA interference
-
Fraser A.G., Kamath R.S., Zipperlen P., Martinez-Campos M., Sohrmann M., Ahringer J. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature. 408:2000;325-330.
-
(2000)
Nature
, vol.408
, pp. 325-330
-
-
Fraser, A.G.1
Kamath, R.S.2
Zipperlen, P.3
Martinez-Campos, M.4
Sohrmann, M.5
Ahringer, J.6
-
13
-
-
0037448540
-
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
-
Kamath R.S., Fraser A.G., Dong Y., Poulin G., Durbin R., Gotta M.et al. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature. 421:2003;231-237.
-
(2003)
Nature
, vol.421
, pp. 231-237
-
-
Kamath, R.S.1
Fraser, A.G.2
Dong, Y.3
Poulin, G.4
Durbin, R.5
Gotta, M.6
-
14
-
-
0032538391
-
RNAi in C. elegans: Soaking in the genome sequence
-
Tabara H., Grishok A., Mello C.C. RNAi in C. elegans: soaking in the genome sequence. Science. 282:1998;430-431.
-
(1998)
Science
, vol.282
, pp. 430-431
-
-
Tabara, H.1
Grishok, A.2
Mello, C.C.3
-
15
-
-
0034789243
-
Post-transcriptional gene silencing in plants
-
Vaucheret H., Beclin C., Fagard M. Post-transcriptional gene silencing in plants. J. Cell Sci. 114:2001;3083-3091.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 3083-3091
-
-
Vaucheret, H.1
Beclin, C.2
Fagard, M.3
-
16
-
-
0034612276
-
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
-
Clemens J.C., Worby C.A., Simonson-Leff N., Muda M., Maehama T., Hemmings B.A.et al. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc. Natl. Acad. Sci. U.S.A. 97:2000;6499-6503.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 6499-6503
-
-
Clemens, J.C.1
Worby, C.A.2
Simonson-Leff, N.3
Muda, M.4
Maehama, T.5
Hemmings, B.A.6
-
17
-
-
0036591878
-
The many faces of histone lysine methylation
-
Lachner M., Jenuwein T. The many faces of histone lysine methylation. Curr. Opin. Cell Biol. 14:2002;286-298.
-
(2002)
Curr. Opin. Cell Biol.
, vol.14
, pp. 286-298
-
-
Lachner, M.1
Jenuwein, T.2
-
18
-
-
0036788304
-
Gene silencing in mammals by small interfering RNAs
-
McManus M.T., Sharp P.A. Gene silencing in mammals by small interfering RNAs. Nat. Rev. Genet. 3:2002;737-747.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 737-747
-
-
McManus, M.T.1
Sharp, P.A.2
-
19
-
-
0033230617
-
PKR; A sentinel kinase for cellular stress
-
Williams B.R. PKR; a sentinel kinase for cellular stress. Oncogene. 18:1999;6112-6120.
-
(1999)
Oncogene
, vol.18
, pp. 6112-6120
-
-
Williams, B.R.1
-
20
-
-
0031657551
-
How cells respond to interferons
-
Stark G.R., Kerr I.M., Williams B.R., Silverman R.H., Schreiber R.D. How cells respond to interferons. Annu. Rev. Biochem. 67:1998;227-264.
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.3
Silverman, R.H.4
Schreiber, R.D.5
-
21
-
-
0034737298
-
RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
-
Zamore P.D., Tuschl T., Sharp P.A., Bartel D.P. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell. 101:2000;25-33.
-
(2000)
Cell
, vol.101
, pp. 25-33
-
-
Zamore, P.D.1
Tuschl, T.2
Sharp, P.A.3
Bartel, D.P.4
-
22
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
-
Hammond S.M., Bernstein E., Beach D., Hannon G.J. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature. 404:2000;293-296.
-
(2000)
Nature
, vol.404
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
23
-
-
0034609759
-
Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos
-
Yang D., Lu H., Erickson J.W. Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos. Curr. Biol. 10:2000;1191-1200.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1191-1200
-
-
Yang, D.1
Lu, H.2
Erickson, J.W.3
-
24
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E., Caudy A.A., Hammond S.M., Hannon G.J. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature. 409:2001;363-366.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
25
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
Elbashir S.M., Lendeckel W., Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15:2001;188-200.
-
(2001)
Genes Dev.
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
27
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir S.M., Harborth J., Lendeckel W., Yalcin A., Weber K., Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 411:2001;494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
28
-
-
0035803583
-
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
-
Elbashir S.M., Martinez J., Patkaniowska A., Lendeckel W., Tuschl T. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20:2001;6877-6888.
-
(2001)
EMBO J.
, vol.20
, pp. 6877-6888
-
-
Elbashir, S.M.1
Martinez, J.2
Patkaniowska, A.3
Lendeckel, W.4
Tuschl, T.5
-
29
-
-
0037162522
-
Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
-
Yang D., Buchholz F., Huang Z., Goga A., Chen C.Y., Brodsky F.M.et al. Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 99:2002;9942-9947.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 9942-9947
-
-
Yang, D.1
Buchholz, F.2
Huang, Z.3
Goga, A.4
Chen, C.Y.5
Brodsky, F.M.6
-
30
-
-
0037038389
-
Gene centre chips in with better route to microarrays
-
Abbott A. Gene centre chips in with better route to microarrays. Nature. 420:2002;3.
-
(2002)
Nature
, vol.420
, pp. 3
-
-
Abbott, A.1
-
31
-
-
0035859929
-
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
-
Caplen N.J., Parrish S., Imani F., Fire A., Morgan R.A. Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc. Natl. Acad. Sci. U.S.A. 98:2001;9742-9747.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 9742-9747
-
-
Caplen, N.J.1
Parrish, S.2
Imani, F.3
Fire, A.4
Morgan, R.A.5
-
32
-
-
0037173610
-
Modulation of HIV-1 replication by RNA interference
-
Jacque J.M., Triques K., Stevenson M. Modulation of HIV-1 replication by RNA interference. Nature. 418:2002;435-438.
-
(2002)
Nature
, vol.418
, pp. 435-438
-
-
Jacque, J.M.1
Triques, K.2
Stevenson, M.3
-
33
-
-
0037111232
-
Small interfering RNA-mediated gene silencing in T lymphocytes
-
McManus M.T., Haines B.B., Dillon C.P., Whitehurst C.E., van Parijs L., Chen J.et al. Small interfering RNA-mediated gene silencing in T lymphocytes. J. Immunol. 169:2002;5754-5760.
-
(2002)
J. Immunol.
, vol.169
, pp. 5754-5760
-
-
McManus, M.T.1
Haines, B.B.2
Dillon, C.P.3
Whitehurst, C.E.4
Van Parijs, L.5
Chen, J.6
-
34
-
-
0037069417
-
Retroviral delivery of small interfering RNA into primary cells
-
Barton G.M., Medzhitov R. Retroviral delivery of small interfering RNA into primary cells. Proc. Natl. Acad. Sci. U.S.A. 99:2002;14943-14945.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 14943-14945
-
-
Barton, G.M.1
Medzhitov, R.2
-
35
-
-
0037112178
-
Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence
-
Zou X., Ray D., Aziyu A., Christov K., Boiko A.D., Gudkov A.V.et al. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence. Genes Dev. 16:2002;2923-2934.
-
(2002)
Genes Dev.
, vol.16
, pp. 2923-2934
-
-
Zou, X.1
Ray, D.2
Aziyu, A.3
Christov, K.4
Boiko, A.D.5
Gudkov, A.V.6
-
37
-
-
18644382388
-
The polycomb group protein EZH2 is involved in progression of prostate cancer
-
Varambally S., Dhanasekaran S.M., Zhou M., Barrette T.R., Kumar-Sinha C., Sanda M.G.et al. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature. 419:2002;624-629.
-
(2002)
Nature
, vol.419
, pp. 624-629
-
-
Varambally, S.1
Dhanasekaran, S.M.2
Zhou, M.3
Barrette, T.R.4
Kumar-Sinha, C.5
Sanda, M.G.6
-
38
-
-
0036358853
-
RNAi (Nematodes: Caenorhabditis elegans)
-
Grishok A., Mello C.C. RNAi (Nematodes: Caenorhabditis elegans). Adv. Genet. 46:2002;339-360.
-
(2002)
Adv. Genet.
, vol.46
, pp. 339-360
-
-
Grishok, A.1
Mello, C.C.2
-
39
-
-
0037192490
-
Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1
-
Winston W.M., Molodowitch C., Hunter C.P. Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1. Science. 295:2002;2456-2459.
-
(2002)
Science
, vol.295
, pp. 2456-2459
-
-
Winston, W.M.1
Molodowitch, C.2
Hunter, C.P.3
-
40
-
-
0037150729
-
Recent advances in cancer research: Mouse models of tumorigenesis
-
Herzig M., Christofori G. Recent advances in cancer research: mouse models of tumorigenesis. Biochim. Biophys. Acta. 1602:2002;97-113.
-
(2002)
Biochim. Biophys. Acta
, vol.1602
, pp. 97-113
-
-
Herzig, M.1
Christofori, G.2
-
41
-
-
0031021132
-
Mouse models of human disease. Part I. Techniques and resources for genetic analysis in mice
-
Bedell M.A., Jenkins N.A., Copeland N.G. Mouse models of human disease. Part I. Techniques and resources for genetic analysis in mice. Genes Dev. 11:1997;1-10.
-
(1997)
Genes Dev.
, vol.11
, pp. 1-10
-
-
Bedell, M.A.1
Jenkins, N.A.2
Copeland, N.G.3
-
42
-
-
0031028759
-
Mouse models of human disease. Part II. Recent progress and future directions
-
Bedell M.A., Largaespada D.A., Jenkins N.A., Copeland N.G. Mouse models of human disease. Part II. Recent progress and future directions. Genes Dev. 11:1997;11-43.
-
(1997)
Genes Dev.
, vol.11
, pp. 11-43
-
-
Bedell, M.A.1
Largaespada, D.A.2
Jenkins, N.A.3
Copeland, N.G.4
-
43
-
-
0036727416
-
Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
-
Lewis D.L., Hagstrom J.E., Loomis A.G., Wolff J.A., Herweijer H. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 32:2002;107-108.
-
(2002)
Nat. Genet.
, vol.32
, pp. 107-108
-
-
Lewis, D.L.1
Hagstrom, J.E.2
Loomis, A.G.3
Wolff, J.A.4
Herweijer, H.5
-
44
-
-
0037019339
-
RNA interference in adult mice
-
McCaffrey A.P., Meuse L., Pham T.T., Conklin D.S., Hannon G.J., Kay M.A. RNA interference in adult mice. Nature. 418:2002;38-39.
-
(2002)
Nature
, vol.418
, pp. 38-39
-
-
McCaffrey, A.P.1
Meuse, L.2
Pham, T.T.3
Conklin, D.S.4
Hannon, G.J.5
Kay, M.A.6
-
45
-
-
0033166561
-
High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA
-
Zhang G., Budker V., Wolff J.A. High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA. Hum. Gene Ther. 10:1999;1735-1737.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 1735-1737
-
-
Zhang, G.1
Budker, V.2
Wolff, J.A.3
-
46
-
-
0032805251
-
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
-
Liu F., Song Y., Liu D. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther. 6:1999;1258-1266.
-
(1999)
Gene Ther.
, vol.6
, pp. 1258-1266
-
-
Liu, F.1
Song, Y.2
Liu, D.3
-
48
-
-
0037021437
-
Small interfering RNA and gene silencing in transgenic mice and rats
-
Hasuwa H., Kaseda K., Einarsdottir T., Okabe M. Small interfering RNA and gene silencing in transgenic mice and rats. FEBS Lett. 532:2002;227-230.
-
(2002)
FEBS Lett.
, vol.532
, pp. 227-230
-
-
Hasuwa, H.1
Kaseda, K.2
Einarsdottir, T.3
Okabe, M.4
-
49
-
-
0036385852
-
Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo
-
Bertrand J.R., Pottier M., Vekris A., Opolon P., Maksimenko A., Malvy C. Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo. Biochem. Biophys. Res. Commun. 296:2002;1000-1004.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.296
, pp. 1000-1004
-
-
Bertrand, J.R.1
Pottier, M.2
Vekris, A.3
Opolon, P.4
Maksimenko, A.5
Malvy, C.6
-
50
-
-
0033789992
-
Specific interference with gene function by double-stranded RNA in early mouse development
-
Wianny F., Zernicka-Goetz M. Specific interference with gene function by double-stranded RNA in early mouse development. Nat. Cell Biol. 2:2000;70-75.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 70-75
-
-
Wianny, F.1
Zernicka-Goetz, M.2
-
51
-
-
0033766888
-
Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference
-
Svoboda P., Stein P., Hayashi H., Schultz R.M. Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference. Development. 127:2000;4147-4156.
-
(2000)
Development
, vol.127
, pp. 4147-4156
-
-
Svoboda, P.1
Stein, P.2
Hayashi, H.3
Schultz, R.M.4
-
52
-
-
0036389623
-
Successful inactivation of endogenous Oct-3/4 and c-mos genes in mouse preimplantation embryos and oocytes using short interfering RNAs
-
Kim M.H., Yuan X., Okumura S., Ishikawa F. Successful inactivation of endogenous Oct-3/4 and c-mos genes in mouse preimplantation embryos and oocytes using short interfering RNAs. Biochem. Biophys. Res. Commun. 296:2002;1372-1377.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.296
, pp. 1372-1377
-
-
Kim, M.H.1
Yuan, X.2
Okumura, S.3
Ishikawa, F.4
-
53
-
-
0037195064
-
Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA
-
Calegari F., Haubensak W., Yang D., Huttner W.B., Buchholz F. Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA. Proc. Natl. Acad. Sci. U.S.A. 99:2002;14236-14240.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 14236-14240
-
-
Calegari, F.1
Haubensak, W.2
Yang, D.3
Huttner, W.B.4
Buchholz, F.5
-
55
-
-
0034854565
-
Gene transfer into cultured mammalian embryos by electroporation
-
Osumi N., Inoue T. Gene transfer into cultured mammalian embryos by electroporation. Methods. 24:2001;35-42.
-
(2001)
Methods
, vol.24
, pp. 35-42
-
-
Osumi, N.1
Inoue, T.2
-
56
-
-
0036595981
-
Manipulating gene expressions by electroporation in the developing brain of mammalian embryos
-
Takahashi M., Sato K., Nomura T., Osumi N. Manipulating gene expressions by electroporation in the developing brain of mammalian embryos. Differentiation. 70:2002;155-162.
-
(2002)
Differentiation
, vol.70
, pp. 155-162
-
-
Takahashi, M.1
Sato, K.2
Nomura, T.3
Osumi, N.4
-
58
-
-
0037449534
-
Gene therapy. Second child in French trial is found to have leukemia
-
Marshall E. Gene therapy. Second child in French trial is found to have leukemia. Science. 299:2003;320.
-
(2003)
Science
, vol.299
, pp. 320
-
-
Marshall, E.1
-
59
-
-
0037007828
-
Small interfering RNAs and their chemical synthesis
-
Micura R. Small interfering RNAs and their chemical synthesis. Angew Chem. Int. Ed. Engl. 41:2002;2265-2269.
-
(2002)
Angew Chem. Int. Ed. Engl.
, vol.41
, pp. 2265-2269
-
-
Micura, R.1
-
60
-
-
0037197914
-
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
-
Yu J.Y., DeRuiter S.L., Turner D.L. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 99:2002;6047-6052.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 6047-6052
-
-
Yu, J.Y.1
Deruiter, S.L.2
Turner, D.L.3
-
61
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
Paddison P.J., Caudy A.A., Bernstein E., Hannon G.J., Conklin D.S. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16:2002;948-958.
-
(2002)
Genes Dev.
, vol.16
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
Hannon, G.J.4
Conklin, D.S.5
-
62
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp T.R., Bernards R., Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science. 296:2002;550-553.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
64
-
-
0036245628
-
U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
-
Miyagishi M., Taira K. U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat. Biotechnol. 20:2002;497-500.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 497-500
-
-
Miyagishi, M.1
Taira, K.2
-
65
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
Sui G., Soohoo C., Affar el B., Gay F., Shi Y., Forrester W.C. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 99:2002;5515-5520.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 5515-5520
-
-
Sui, G.1
Soohoo, C.2
El, A.B.3
Gay, F.4
Shi, Y.5
Forrester, W.C.6
-
66
-
-
0037224722
-
DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells
-
Robert M.F., Morin S., Beaulieu N., Gauthier F., Chute I.C., Barsalou A.et al. DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. Nat. Genet. 33:2003;61-65.
-
(2003)
Nat. Genet.
, vol.33
, pp. 61-65
-
-
Robert, M.F.1
Morin, S.2
Beaulieu, N.3
Gauthier, F.4
Chute, I.C.5
Barsalou, A.6
-
67
-
-
0037151042
-
Methyl-CpG binding domain protein 2 represses transcription from hypermethylated pi-class glutathione-S-transferase gene promoters in hepatocellular carcinoma cells
-
Bakker J., Lin X., Nelson W.G. Methyl-CpG binding domain protein 2 represses transcription from hypermethylated pi-class glutathione-S-transferase gene promoters in hepatocellular carcinoma cells. J. Biol. Chem. 277:2002;22573-22580.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 22573-22580
-
-
Bakker, J.1
Lin, X.2
Nelson, W.G.3
-
68
-
-
0036902410
-
53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer
-
DiTullio R.A. Jr., Mochan T.A., Venere M., Bartkova J., Sehested M., Bartek J.et al. 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer. Nat. Cell Biol. 4:2002;998-1002.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 998-1002
-
-
Ditullio, R.A.Jr.1
Mochan, T.A.2
Venere, M.3
Bartkova, J.4
Sehested, M.5
Bartek, J.6
-
69
-
-
0037112212
-
53BP1, a mediator of the DNA damage checkpoint
-
Wang B., Matsuoka S., Carpenter P.B., Elledge S.J. 53BP1, a mediator of the DNA damage checkpoint. Science. 298:2002;1435-1438.
-
(2002)
Science
, vol.298
, pp. 1435-1438
-
-
Wang, B.1
Matsuoka, S.2
Carpenter, P.B.3
Elledge, S.J.4
-
70
-
-
0037119943
-
DEDD regulates degradation of intermediate filaments during apoptosis
-
Lee J.C., Schickling O., Stegh A.H., Oshima R.G., Dinsdale D., Cohen G.M.et al. DEDD regulates degradation of intermediate filaments during apoptosis. J. Cell Biol. 158:2002;1051-1066.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 1051-1066
-
-
Lee, J.C.1
Schickling, O.2
Stegh, A.H.3
Oshima, R.G.4
Dinsdale, D.5
Cohen, G.M.6
-
71
-
-
0037162833
-
Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization
-
Lassus P., Opitz-Araya X., Lazebnik Y. Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science. 297:2002;1352-1354.
-
(2002)
Science
, vol.297
, pp. 1352-1354
-
-
Lassus, P.1
Opitz-Araya, X.2
Lazebnik, Y.3
-
72
-
-
0037130473
-
P53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop
-
Kartasheva N.N., Contente A., Lenz-Stoppler C., Roth J., Dobbelstein M. p53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop. Oncogene. 21:2002;4715-4727.
-
(2002)
Oncogene
, vol.21
, pp. 4715-4727
-
-
Kartasheva, N.N.1
Contente, A.2
Lenz-Stoppler, C.3
Roth, J.4
Dobbelstein, M.5
-
73
-
-
0037020234
-
Physical and functional interaction between myeloid cell leukemia 1 protein (MCL1) and Fortilin. The potential role of MCL1 as a fortilin chaperone
-
Zhang D., Li F., Weidner D., Mnjoyan Z.H., Fujise K. Physical and functional interaction between myeloid cell leukemia 1 protein (MCL1) and Fortilin. The potential role of MCL1 as a fortilin chaperone. J. Biol. Chem. 277:2002;37430-37438.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37430-37438
-
-
Zhang, D.1
Li, F.2
Weidner, D.3
Mnjoyan, Z.H.4
Fujise, K.5
-
74
-
-
0037462796
-
Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage
-
Yoon H.S., Chen X., Yang V.W. Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage. J. Biol. Chem. 278:2003;2101-2105.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2101-2105
-
-
Yoon, H.S.1
Chen, X.2
Yang, V.W.3
-
75
-
-
0036745763
-
CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells
-
Chen Z., Indjeian V.B., McManus M., Wang L., Dynlacht B.D. CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells. Dev. Cell. 3:2002;339-350.
-
(2002)
Dev. Cell
, vol.3
, pp. 339-350
-
-
Chen, Z.1
Indjeian, V.B.2
McManus, M.3
Wang, L.4
Dynlacht, B.D.5
-
76
-
-
0037193461
-
Human speedy: A novel cell cycle regulator that enhances proliferation through activation of Cdk2
-
Porter L.A., Dellinger R.W., Tynan J.A., Barnes E.A., Kong M., Leromand J.L.et al. Human speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2. J. Cell Biol. 157:2002;357-366.
-
(2002)
J. Cell Biol.
, vol.157
, pp. 357-366
-
-
Porter, L.A.1
Dellinger, R.W.2
Tynan, J.A.3
Barnes, E.A.4
Kong, M.5
Leromand, J.L.6
-
77
-
-
0037108955
-
P300 mediates androgen-independent transactivation of the androgen receptor by interleukin 6
-
Debes J.D., Schmidt L.J., Huang H., Tindall D.J. P300 mediates androgen-independent transactivation of the androgen receptor by interleukin 6. Cancer Res. 62:2002;5632-5636.
-
(2002)
Cancer Res.
, vol.62
, pp. 5632-5636
-
-
Debes, J.D.1
Schmidt, L.J.2
Huang, H.3
Tindall, D.J.4
-
78
-
-
0036841720
-
Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases
-
Shu X., Wu W., Mosteller R.D., Broek D. Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases. Mol. Cell. Biol. 22:2002;7758-7768.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7758-7768
-
-
Shu, X.1
Wu, W.2
Mosteller, R.D.3
Broek, D.4
-
79
-
-
0037135578
-
Mediation of the DCC apoptotic signal by DIP13 alpha
-
Liu J., Yao F., Wu R., Morgan M., Thorburn A., Finley R.L. Jr.et al. Mediation of the DCC apoptotic signal by DIP13 alpha. J. Biol. Chem. 277:2002;26281-26285.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 26281-26285
-
-
Liu, J.1
Yao, F.2
Wu, R.3
Morgan, M.4
Thorburn, A.5
Finley Jr. et al., R.L.6
-
80
-
-
0037026601
-
Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference
-
Jiang M., Milner J. Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference. Oncogene. 21:2002;6041-6048.
-
(2002)
Oncogene
, vol.21
, pp. 6041-6048
-
-
Jiang, M.1
Milner, J.2
-
81
-
-
0038047685
-
AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells
-
Heidenreich O., Krauter J., Riehle H., Hadwiger P., John M., Heil G.et al. AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells. Blood. 101:2003;3157-3163.
-
(2003)
Blood
, vol.101
, pp. 3157-3163
-
-
Heidenreich, O.1
Krauter, J.2
Riehle, H.3
Hadwiger, P.4
John, M.5
Heil, G.6
-
82
-
-
0037441756
-
Specific inhibition of bcr-abl gene expression by small interfering RNA
-
Scherr M., Battmer K., Winkler T., Heidenreich O., Ganser A., Eder M. Specific inhibition of bcr-abl gene expression by small interfering RNA. Blood. 101:2003;1566-1599.
-
(2003)
Blood
, vol.101
, pp. 1566-1599
-
-
Scherr, M.1
Battmer, K.2
Winkler, T.3
Heidenreich, O.4
Ganser, A.5
Eder, M.6
|