-
1
-
-
0026776299
-
Anthracene-9,10-diones as potential anticancer agents -synthesis, DNA-binding and biological studies on a series of 2,6-disubstituted derivatives
-
Agbandje M, Jenkins TC, McKenna R, Reszka AP, Niedle S. 1992. Anthracene-9,10-diones as potential anticancer agents -synthesis, DNA-binding and biological studies on a series of 2,6-disubstituted derivatives. J. Med. Chem. 35: 1418-1429.
-
(1992)
J. Med. Chem.
, vol.35
, pp. 1418-1429
-
-
Agbandje, M.1
Jenkins, T.C.2
McKenna, R.3
Reszka, A.P.4
Niedle, S.5
-
4
-
-
0025731583
-
Structure and function of telomeres
-
Blackburn EH. 1991. Structure and function of telomeres. Nature, 350: 569-573.
-
(1991)
Nature
, vol.350
, pp. 569-573
-
-
Blackburn, E.H.1
-
5
-
-
0039721586
-
Molecular recognition between a new pentacyclic acridinium salt and DNA sequences investigated by optical spectroscopic techniques, proton NMR spectroscopy and molecular modelling
-
Bostock-Smith CE, Gimenez-Arnau E, Missailidis S, Laughton CA, Stevens MFG, Searle MS. 1999. Molecular recognition between a new pentacyclic acridinium salt and DNA sequences investigated by optical spectroscopic techniques, proton NMR spectroscopy and molecular modelling. Biochemistry 38: 6723-6731.
-
(1999)
Biochemistry
, vol.38
, pp. 6723-6731
-
-
Bostock-Smith, C.E.1
Gimenez-Arnau, E.2
Missailidis, S.3
Laughton, C.A.4
Stevens, M.F.G.5
Searle, M.S.6
-
6
-
-
0030465221
-
Dissecting the free energy of drug binding to DNA
-
Chaires JB. 1996. Dissecting the free energy of drug binding to DNA. Anti Cancer Drug Des. 11: 569-580.
-
(1996)
Anti Cancer Drug Des.
, vol.11
, pp. 569-580
-
-
Chaires, J.B.1
-
7
-
-
4143080522
-
Energetics of DNA drug interactions
-
Chaires JB. 1998a. Energetics of DNA drug interactions. Biopolymers 44: 201-215.
-
(1998)
Biopolymers
, vol.44
, pp. 201-215
-
-
Chaires, J.B.1
-
9
-
-
0031045487
-
Structure-based design of a new bisintercalating anthracycline antibiotic
-
Chaires JB, Leng F, Przewloka T, Fokt I, Ling YH, Perez-Soler R, Priebe W. 1997. Structure-based design of a new bisintercalating anthracycline antibiotic. J. Med. Chem. 40: 261-266.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 261-266
-
-
Chaires, J.B.1
Leng, F.2
Przewloka, T.3
Fokt, I.4
Ling, Y.H.5
Perez-Soler, R.6
Priebe, W.7
-
10
-
-
0028402160
-
Binding of two distamycin molecules in the minor-groove of an alternating B-DNA duplex
-
Chen X, Ramakrishnan B, Rao ST, Sundaralingam M. 1994. Binding of two distamycin molecules in the minor-groove of an alternating B-DNA duplex. Nat. Struct. Biol. 1: 169-175.
-
(1994)
Nat. Struct. Biol.
, vol.1
, pp. 169-175
-
-
Chen, X.1
Ramakrishnan, B.2
Rao, S.T.3
Sundaralingam, M.4
-
11
-
-
0029978893
-
Spectroscopic recognition of guanine dimeric hairpin quadraplexes by a carbocyanine dye
-
Chen Q, Kuntz ID, Shafer RH. 1996. Spectroscopic recognition of guanine dimeric hairpin quadraplexes by a carbocyanine dye. Proc. Natl Acad. Sci. USA, 93: 2635-2639.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 2635-2639
-
-
Chen, Q.1
Kuntz, I.D.2
Shafer, R.H.3
-
12
-
-
0025059659
-
Kinetics of the binding of mitoxantrone, ametantrone and analogs to DNA - Relationships with binding mode and antitumour activity
-
Denny WA, Wakelin LPG. 1990. Kinetics of the binding of mitoxantrone, ametantrone and analogs to DNA - relationships with binding mode and antitumour activity. Anti Cancer Drug Des. 5: 189-200.
-
(1990)
Anti Cancer Drug Des.
, vol.5
, pp. 189-200
-
-
Denny, W.A.1
Wakelin, L.P.G.2
-
13
-
-
0344641913
-
Sequence-specific DNA recognition by polyamides
-
Dervan PB, Bürli RW. 1999. Sequence-specific DNA recognition by polyamides. Curr. Opin. Chem. Biol. 3: 688-693.
-
(1999)
Curr. Opin. Chem. Biol.
, vol.3
, pp. 688-693
-
-
Dervan, P.B.1
Bürli, R.W.2
-
14
-
-
0032573224
-
Inhibition of RNA polymerase II transcription in human cells by synthetic DNA binding ligands
-
Dickerson LA, Gulizia RJ, Trauger JW, Baird EE, Mosier DE, Gottersfeld JM, Dervan PB. 1998. Inhibition of RNA polymerase II transcription in human cells by synthetic DNA binding ligands. Proc. Natl Acad. Sci. USA, 95: 12890-12895.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 12890-12895
-
-
Dickerson, L.A.1
Gulizia, R.J.2
Trauger, J.W.3
Baird, E.E.4
Mosier, D.E.5
Gottersfeld, J.M.6
Dervan, P.B.7
-
15
-
-
0032526638
-
Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: Crystal structures of the WP401-TGGCCG and WP401-CGG[BR5C]CG complexes
-
Dutta R, Gao Y-G, Priebe W, Wang H-J. 1998. Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[BR5C]CG complexes. Nucleic Acids Res. 26: 3001-3005.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 3001-3005
-
-
Dutta, R.1
Gao, Y.-G.2
Priebe, W.3
Wang, H.-J.4
-
16
-
-
0028855306
-
Selective stabilisation of DNA triple helices by benzopyridoindole derivatives
-
Escudé C, Nguyen CH, Mergny JL, Sun JS, Bisagni E, Garestier T, Hélène C. 1995. Selective stabilisation of DNA triple helices by benzopyridoindole derivatives. J. Am. Chem. Soc. 117: 10212-10219.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 10212-10219
-
-
Escudé, C.1
Nguyen, C.H.2
Mergny, J.L.3
Sun, J.S.4
Bisagni, E.5
Garestier, T.6
Hélène, C.7
-
17
-
-
13144266674
-
Rational design of a triple helix-specific intercalating ligand
-
Escudé C, Nguyen CH, Kukreti S, Janin Y, Sun JS, Bisagni E, Garestier T, Hélène C. 1998. Rational design of a triple helix-specific intercalating ligand. Proc. Natl Acad. Sci. USA 95: 3591-3596.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 3591-3596
-
-
Escudé, C.1
Nguyen, C.H.2
Kukreti, S.3
Janin, Y.4
Sun, J.S.5
Bisagni, E.6
Garestier, T.7
Hélène, C.8
-
18
-
-
0032497405
-
NMR-based model of a telomerase-inhibiting compound bound to G-quadraplex DNA
-
Fedoroff OY, Salazar M, Han H, Chemeris VV, Kerwin SM, Hurley LH. 1998. NMR-based model of a telomerase-inhibiting compound bound to G-quadraplex DNA. Biochemistry 37: 12367-12374.
-
(1998)
Biochemistry
, vol.37
, pp. 12367-12374
-
-
Fedoroff, O.Y.1
Salazar, M.2
Han, H.3
Chemeris, V.V.4
Kerwin, S.M.5
Hurley, L.H.6
-
19
-
-
0034084567
-
Targeting DNA with triplexes
-
Fox KR. 2000. Targeting DNA with triplexes. Curr. Med. Chem. 7: 17-37.
-
(2000)
Curr. Med. Chem.
, vol.7
, pp. 17-37
-
-
Fox, K.R.1
-
21
-
-
0030601206
-
A novel series of DNA triple-helix binding ligands
-
Fox KR, Thurston DE, Jenkins TC, Varvaresou A, Tsotinis A, Siatra-Papastaikoudi T. 1996. A novel series of DNA triple-helix binding ligands. Biochem. Biophys. Res. Commun. 224: 717-720.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.224
, pp. 717-720
-
-
Fox, K.R.1
Thurston, D.E.2
Jenkins, T.C.3
Varvaresou, A.4
Tsotinis, A.5
Siatra-Papastaikoudi, T.6
-
22
-
-
0027280323
-
NMR characterization of a heterocomplex formed by distamycin and its analog 2-IMD with d(CGCAAGTTGGC)-d(GCCAACTTGCG) - Preferences for the 1:1:1 2-IMD-DST-DNA complex over the 2:1 2-IMD-DNA and the 2:1 DST-DNA complexes
-
Geierstanger BH, Dwyer TJ, Bathini Y, Lown JW, Wemmer DE. 1993. NMR characterization of a heterocomplex formed by distamycin and its analog 2-IMD with d(CGCAAGTTGGC)-d(GCCAACTTGCG) - preferences for the 1:1:1 2-IMD-DST-DNA complex over the 2:1 2-IMD-DNA and the 2:1 DST-DNA complexes. J. Am. Chem. Soc. 115: 4474-4482.
-
(1993)
J. Am. Chem. Soc.
, vol.115
, pp. 4474-4482
-
-
Geierstanger, B.H.1
Dwyer, T.J.2
Bathini, Y.3
Lown, J.W.4
Wemmer, D.E.5
-
25
-
-
0030951207
-
Regulation of gene expression by small molecules
-
Gottersfeld JM, Neely L, Trauger JW, Baird EE, Dervan PB. 1997. Regulation of gene expression by small molecules. Nature 387: 202-205.
-
(1997)
Nature
, vol.387
, pp. 202-205
-
-
Gottersfeld, J.M.1
Neely, L.2
Trauger, J.W.3
Baird, E.E.4
Dervan, P.B.5
-
26
-
-
0022402513
-
Identification of specific telomere terminal transferase activity in Tetrehymena extracts
-
Greider CW, Blackburn EH. 1985. Identification of specific telomere terminal transferase activity in Tetrehymena extracts. Cell 43: 405-413.
-
(1985)
Cell
, vol.43
, pp. 405-413
-
-
Greider, C.W.1
Blackburn, E.H.2
-
27
-
-
0026608237
-
Intercalation of the dye ethidium bromide with DNA containing guanine repeats
-
Guo Q, Lu M, Marky LA, Kallenbach NR. 1992. Intercalation of the dye ethidium bromide with DNA containing guanine repeats. Biochemistry 31: 2451-2455.
-
(1992)
Biochemistry
, vol.31
, pp. 2451-2455
-
-
Guo, Q.1
Lu, M.2
Marky, L.A.3
Kallenbach, N.R.4
-
28
-
-
0342938344
-
Isothermal titration calorimetry in the study of DNA-drug interactions
-
Chowdhry BZ, Ladbury JE. Eds. Wiley, Chichester
-
Haq I. 1998. Isothermal titration calorimetry in the study of DNA-drug interactions. In Biocalorimetry: Applications of Calorimetry in the Biological Sciences. (Chowdhry BZ, Ladbury JE. Eds). Wiley, Chichester.
-
(1998)
Biocalorimetry: Applications of Calorimetry in the Biological Sciences
-
-
Haq, I.1
-
29
-
-
0029821295
-
Molecular anchoring of duplex and triplex DNA by disubstituted anthracene-9,10-diones: Calorimetric, UV melting and competition dialysis studies
-
Haq I, Ladbury JE, Chowdhry BZ, Jenkins TC. 1996. Molecular anchoring of duplex and triplex DNA by disubstituted anthracene-9,10-diones: calorimetric, UV melting and competition dialysis studies. J. Am. Chem. Soc. 118: 10693-10701.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 10693-10701
-
-
Haq, I.1
Ladbury, J.E.2
Chowdhry, B.Z.3
Jenkins, T.C.4
-
31
-
-
0033541133
-
Intercalative G-tetraplex stabilization of telomeric DNA by a cationic porphyrin
-
Haq I, Trent JO, Chowdhry BZ, Jenkins TC. 1999. Intercalative G-tetraplex stabilization of telomeric DNA by a cationic porphyrin. J. Am. Chem. Soc. 121: 1768-1779.
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 1768-1779
-
-
Haq, I.1
Trent, J.O.2
Chowdhry, B.Z.3
Jenkins, T.C.4
-
32
-
-
0034581523
-
Parsing the free energy of drug-DNA interactions
-
Haq I, Jenkins TC, Chowdhry BZ, Ren J, Chaires JB. 2000. Parsing the free energy of drug-DNA interactions. Meth. Enzymol. 323: 373-405.
-
(2000)
Meth. Enzymol.
, vol.323
, pp. 373-405
-
-
Haq, I.1
Jenkins, T.C.2
Chowdhry, B.Z.3
Ren, J.4
Chaires, J.B.5
-
33
-
-
0030958485
-
Structure of a DNA-bisdaunomycin complex
-
Hu GG, Shui X, Leng F, Priebe W, Chaires JB, Williams LD. 1997. Structure of a DNA-bisdaunomycin complex. Biochemistry 36: 5940-5946.
-
(1997)
Biochemistry
, vol.36
, pp. 5940-5946
-
-
Hu, G.G.1
Shui, X.2
Leng, F.3
Priebe, W.4
Chaires, J.B.5
Williams, L.D.6
-
35
-
-
0033083378
-
Effects of cationic porphyrins as G-quadraplex interactive agents in human tumour cells
-
Izbicka E, Wheelhouse RT, Raymond E, Davidson KK, Lawrence RA, Sun D, Windle BE, Hurley LH, Von Hoff DD. 1999. Effects of cationic porphyrins as G-quadraplex interactive agents in human tumour cells. Cancer Res. 59: 639-644.
-
(1999)
Cancer Res.
, vol.59
, pp. 639-644
-
-
Izbicka, E.1
Wheelhouse, R.T.2
Raymond, E.3
Davidson, K.K.4
Lawrence, R.A.5
Sun, D.6
Windle, B.E.7
Hurley, L.H.8
Von Hoff, D.D.9
-
36
-
-
0032901515
-
Isothermal titration calorimetry and differential scanning calorimetry as complementary tools to investigate the energetics of biomolecular recognition
-
Jelesarov I, Bosshard HR. 1999. Isothermal titration calorimetry and differential scanning calorimetry as complementary tools to investigate the energetics of biomolecular recognition. J. Mol. Recogn. 12: 3-18.
-
(1999)
J. Mol. Recogn.
, vol.12
, pp. 3-18
-
-
Jelesarov, I.1
Bosshard, H.R.2
-
37
-
-
0034123587
-
Targeting multi-stranded DNA structures
-
Jenkins TC. 2000. Targeting multi-stranded DNA structures. Curr. Med. Chem. 7: 99-115.
-
(2000)
Curr. Med. Chem.
, vol.7
, pp. 99-115
-
-
Jenkins, T.C.1
-
39
-
-
0026591751
-
Crystal structure of four-stranded Oxytricha telomeric DNA
-
Kang C, Zhang X, Ratliff R, Moyzis R, Rich A. 1992. Crystal structure of four-stranded Oxytricha telomeric DNA. Nature 356: 126-131.
-
(1992)
Nature
, vol.356
, pp. 126-131
-
-
Kang, C.1
Zhang, X.2
Ratliff, R.3
Moyzis, R.4
Rich, A.5
-
40
-
-
0032475994
-
A structural basis for recognition of AT and T-A base pairs in the minor groove of B-DNA
-
Kielkopf CL, White SE, Szewczyk JW, Turner JM, Baird EE, Dervan PB, Rees DC. 1998a. A structural basis for recognition of AT and T-A base pairs in the minor groove of B-DNA. Science 282: 111-115.
-
(1998)
Science
, vol.282
, pp. 111-115
-
-
Kielkopf, C.L.1
White, S.E.2
Szewczyk, J.W.3
Turner, J.M.4
Baird, E.E.5
Dervan, P.B.6
Rees, D.C.7
-
42
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PLC, Coviello GM, Wright WE, Weinrich SL, Shay JW. 1994. Specific association of human telomerase activity with immortal cells and cancer. Science 266: 2011-2015.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.C.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
43
-
-
0031195250
-
Binding geometries of triple helix selective of benzopyrido[4,3-b]indole ligands complexed with double- and triple-helical polynucleotides
-
Kim SK, Sun JS, Garestier T, Hélène C, Nguyen CH, Bisagni E, Rodger A, Norden B. 1997. Binding geometries of triple helix selective of benzopyrido[4,3-b]indole ligands complexed with double- and triple-helical polynucleotides. Biopolymers 42: 101-111.
-
(1997)
Biopolymers
, vol.42
, pp. 101-111
-
-
Kim, S.K.1
Sun, J.S.2
Garestier, T.3
Hélène, C.4
Nguyen, C.H.5
Bisagni, E.6
Rodger, A.7
Norden, B.8
-
45
-
-
0021959842
-
The molecular origin of DNA drug specificity in netropsin and distamycin
-
Kopka ML, Yoon C, Goodsell D, Pjura P, Dickerson RE. 1985b. The molecular origin of DNA drug specificity in netropsin and distamycin. Proc. Natl Acad. Sci. USA 82: 1376-1380.
-
(1985)
Proc. Natl Acad. Sci. USA
, vol.82
, pp. 1376-1380
-
-
Kopka, M.L.1
Yoon, C.2
Goodsell, D.3
Pjura, P.4
Dickerson, R.E.5
-
46
-
-
0029645119
-
Counting the calories to stay in the groove
-
Ladbury JE. 1995. Counting the calories to stay in the groove. Structure 3: 635-639.
-
(1995)
Structure
, vol.3
, pp. 635-639
-
-
Ladbury, J.E.1
-
47
-
-
0028024737
-
The high resolution crystal structure of a parallel stranded guanine tetraplex
-
Laughlan G, Murchie AIH, Norman DG, Moore MH, Moody PCE, Lilley DMJ, Luisi B. 1994. The high resolution crystal structure of a parallel stranded guanine tetraplex. Science 265: 520-524.
-
(1994)
Science
, vol.265
, pp. 520-524
-
-
Laughlan, G.1
Murchie, A.I.H.2
Norman, D.G.3
Moore, M.H.4
Moody, P.C.E.5
Lilley, D.M.J.6
Luisi, B.7
-
48
-
-
0032539641
-
Ultralight DNA binding of a new bisintercalating anthracycline antibiotic
-
Leng F, Priebe W, Chaires JB. 1998. Ultralight DNA binding of a new bisintercalating anthracycline antibiotic. Biochemistry 37: 1743-1753.
-
(1998)
Biochemistry
, vol.37
, pp. 1743-1753
-
-
Leng, F.1
Priebe, W.2
Chaires, J.B.3
-
49
-
-
85048645035
-
Structural considerations in the interaction of DNA and acridines
-
Lerman LS. 1961. Structural considerations in the interaction of DNA and acridines. J. Mol. Biol. 3: 18-30.
-
(1961)
J. Mol. Biol.
, vol.3
, pp. 18-30
-
-
Lerman, L.S.1
-
50
-
-
0001877793
-
The structure of the DNA-acridine complex
-
Lerman LS. 1963. The structure of the DNA-acridine complex. Proc. Natl Acad. Sci. USA 49: 94-102.
-
(1963)
Proc. Natl Acad. Sci. USA
, vol.49
, pp. 94-102
-
-
Lerman, L.S.1
-
51
-
-
0022858456
-
Molecular recognition between oligo-peptides and nucleic acids: Novel imidazole containing oligopeptides related to netropsin that exhibit altered DNA sequence specificity
-
Lown JW, Krowicki K, Bhat UG, Skorobogaty A, Ward B, Dabrowiak JC. 1986. Molecular recognition between oligo-peptides and nucleic acids: novel imidazole containing oligopeptides related to netropsin that exhibit altered DNA sequence specificity. Biochemistry 25: 7408-7416.
-
(1986)
Biochemistry
, vol.25
, pp. 7408-7416
-
-
Lown, J.W.1
Krowicki, K.2
Bhat, U.G.3
Skorobogaty, A.4
Ward, B.5
Dabrowiak, J.C.6
-
52
-
-
0031000884
-
Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
-
Makarov VL, Hirose Y, Langmore JP. 1997. Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell 88: 657-666.
-
(1997)
Cell
, vol.88
, pp. 657-666
-
-
Makarov, V.L.1
Hirose, Y.2
Langmore, J.P.3
-
53
-
-
0002767352
-
Calorimetric studies of drug-DNA interactions
-
(Hurley L. H. and Chaires J. B. Eds.) JAI Press, Greenwich, CT
-
Marky LA, Alessi K, Rentzeperis D. 1996. Calorimetric studies of drug-DNA interactions. In Advances in DNA Sequence Specific Agents, Vol 2 (Hurley L. H. and Chaires J. B. Eds.) JAI Press, Greenwich, CT.
-
(1996)
Advances in DNA Sequence Specific Agents
, vol.2
-
-
Marky, L.A.1
Alessi, K.2
Rentzeperis, D.3
-
54
-
-
0026696129
-
Triple helix-specific ligands
-
Mergny JL, Duval-Valentin G, Nguyen CH, Perrouault L, Faucon B, Rougée M, Montenay-Garestier T, Bisagni E, Hélène C. 1992. Triple helix-specific ligands. Science 256: 1681-1684.
-
(1992)
Science
, vol.256
, pp. 1681-1684
-
-
Mergny, J.L.1
Duval-Valentin, G.2
Nguyen, C.H.3
Perrouault, L.4
Faucon, B.5
Rougée, M.6
Montenay-Garestier, T.7
Bisagni, E.8
Hélène, C.9
-
55
-
-
0032718247
-
The development of telomerase inhibitors: The G-quartet approach
-
Mergny J-L, Mailliet P, Lavelle F, Riou J-F, Laoui A, Hélène C. 1999. The development of telomerase inhibitors: the G-quartet approach. Anti Cancer Drug Des. 14: 327-339.
-
(1999)
Anti Cancer Drug Des.
, vol.14
, pp. 327-339
-
-
Mergny, J.-L.1
Mailliet, P.2
Lavelle, F.3
Riou, J.-F.4
Laoui, A.5
Hélène, C.6
-
56
-
-
0026661689
-
Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin
-
Mrksich M, Wade WS, Dwyer TJ, Geierstanger BH, Wemmer DE, Dervan PB. 1992. Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin. Proc. Nat. Acad. Sci. USA 89: 7586-7590.
-
(1992)
Proc. Nat. Acad. Sci. USA
, vol.89
, pp. 7586-7590
-
-
Mrksich, M.1
Wade, W.S.2
Dwyer, T.J.3
Geierstanger, B.H.4
Wemmer, D.E.5
Dervan, P.B.6
-
57
-
-
0027970146
-
Hairpin peptide motif: A new class of oligopeptides for sequence-specific recognition in the minor groove of double helical DNA
-
Mrksich M, Parks ME, Dervan PB. 1994. Hairpin peptide motif: a new class of oligopeptides for sequence-specific recognition in the minor groove of double helical DNA. J. Am. Chem. Soc. 1165: 7983-7988.
-
(1994)
J. Am. Chem. Soc.
, vol.1165
, pp. 7983-7988
-
-
Mrksich, M.1
Parks, M.E.2
Dervan, P.B.3
-
58
-
-
0001641412
-
Synthesis of 13H-benzo[6,7]- and 13H-benzo[4,5]indolo[3,2-c]-quinoline: A new series of potent specific ligands for triplex DNA
-
Nguyen CH, Marchand C, Delage S, Sun JS, Garestier T, Hélène C, Bisagni E. 1998. Synthesis of 13H-benzo[6,7]- and 13H-benzo[4,5]indolo[3,2-c]-quinoline: a new series of potent specific ligands for triplex DNA. J. Am. Chem. Soc. 120: 2501-2507.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 2501-2507
-
-
Nguyen, C.H.1
Marchand, C.2
Delage, S.3
Sun, J.S.4
Garestier, T.5
Hélène, C.6
Bisagni, E.7
-
59
-
-
0026337344
-
Molecular modelling to study DNA intercalation by antitumour drugs
-
Niedle S, Jenkins TC. 1991. Molecular modelling to study DNA intercalation by antitumour drugs. Meth. Enzymol. 203: 433-458.
-
(1991)
Meth. Enzymol.
, vol.203
, pp. 433-458
-
-
Niedle, S.1
Jenkins, T.C.2
-
60
-
-
0032739776
-
Recent advances in the development of telomerase inhibitors for the treatment of cancer
-
Perry PJ, Jenkins TC. 1999. Recent advances in the development of telomerase inhibitors for the treatment of cancer. Expert Opin. Invest. Drugs 8: 1981-2008.
-
(1999)
Expert Opin. Invest. Drugs
, vol.8
, pp. 1981-2008
-
-
Perry, P.J.1
Jenkins, T.C.2
-
61
-
-
0031760366
-
Telomeres and telomerase: Targets for cancer chemotherapy?
-
Perry PJ, Kelland LR. 1998. Telomeres and telomerase: targets for cancer chemotherapy? Expert Opin. Ther. Patents 8: 1567-1586.
-
(1998)
Expert Opin. Ther. Patents
, vol.8
, pp. 1567-1586
-
-
Perry, P.J.1
Kelland, L.R.2
-
62
-
-
7844223625
-
Human telomerase inhibition by regioisomeric disubstituted amidoanthracene-9,10-diones
-
Perry PJ, Reszka AP, Wood AA, Read MA, Gowan SM, Dosanjh HS, Trent JO, Jenkins TC, Kelland LR, Niedle S. 1998a. Human telomerase inhibition by regioisomeric disubstituted amidoanthracene-9,10-diones. J. Med. Chem. 41: 4873-4884.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 4873-4884
-
-
Perry, P.J.1
Reszka, A.P.2
Wood, A.A.3
Read, M.A.4
Gowan, S.M.5
Dosanjh, H.S.6
Trent, J.O.7
Jenkins, T.C.8
Kelland, L.R.9
Niedle, S.10
-
63
-
-
0032514479
-
1,4- and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase
-
Perry PJ, Gowan SM, Reszka AP, Polucci P, Jenkins TC, Kelland LR, Niedle S. 1998b. 1,4- and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase. J. Med. Chem. 41: 3253-3260.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 3253-3260
-
-
Perry, P.J.1
Gowan, S.M.2
Reszka, A.P.3
Polucci, P.4
Jenkins, T.C.5
Kelland, L.R.6
Niedle, S.7
-
64
-
-
0029776688
-
Binding of a hairpin polyamide in the minor groove of DNA: Sequence-specific enthalpic discrimination
-
Pilch DS, Poklar N, Gelfand CA, Law SM, Breslauer KJ, Baird EE, Deravn PB. 1996. Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discrimination. Proc. Natl Acad. Sci. USA 93: 8306-8311.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 8306-8311
-
-
Pilch, D.S.1
Poklar, N.2
Gelfand, C.A.3
Law, S.M.4
Breslauer, K.J.5
Baird, E.E.6
Deravn, P.B.7
-
65
-
-
0033573863
-
The thermodynamics of polyamide-DNA recognition: Hairpin polyamide binding in the minor groove of duplex DNA
-
Pilch DS, Poklar N, Baird EE, Dervan PB, Breslauer KJ. 1999. The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA. Biochemistry 38: 2143-2151.
-
(1999)
Biochemistry
, vol.38
, pp. 2143-2151
-
-
Pilch, D.S.1
Poklar, N.2
Baird, E.E.3
Dervan, P.B.4
Breslauer, K.J.5
-
66
-
-
0001635854
-
Thermodynamics of olgonucleotide triple helices
-
Plum GE. 1998. Thermodynamics of olgonucleotide triple helices. Bioploymers 44: 241-256.
-
(1998)
Bioploymers
, vol.44
, pp. 241-256
-
-
Plum, G.E.1
-
67
-
-
0032750623
-
Triple helix formation and the antigene strategy for sequence-specific control of gene expression
-
Praseuth D, Guieysse AL, Hélène C. 1999. Triple helix formation and the antigene strategy for sequence-specific control of gene expression. Biochim. Biophys. Acta 1489: 181-206.
-
(1999)
Biochim. Biophys. Acta
, vol.1489
, pp. 181-206
-
-
Praseuth, D.1
Guieysse, A.L.2
Hélène, C.3
-
68
-
-
0011166658
-
Anthracycline antibiotics: New analogues, methods of delivery and mechanisms of action
-
Americal Chemical Society, Washington, DC
-
Priebe W. 1995. Anthracycline Antibiotics: New Analogues, Methods of Delivery and Mechanisms of Action. ACS Symposium Series 574, Americal Chemical Society, Washington, DC.
-
(1995)
ACS Symposium Series 574
-
-
Priebe, W.1
-
69
-
-
0033958577
-
Preferential binding of 3,3-diethyloxa-dicarbocyanine to triplex DNA
-
Ren J, Chaires JB. 2000. Preferential binding of 3,3-Diethyloxa-dicarbocyanine to triplex DNA. J. Am. Chem. Soc. 122: 424-425.
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 424-425
-
-
Ren, J.1
Chaires, J.B.2
-
70
-
-
0030840016
-
Binding of two novel bisdaunorubicins to DNA studies by NMR spectroscopy
-
Robinson H, Priebe W, Chaires JB, Wang AH. 1997. Binding of two novel bisdaunorubicins to DNA studies by NMR spectroscopy. Biochemistry 36: 8663-8670.
-
(1997)
Biochemistry
, vol.36
, pp. 8663-8670
-
-
Robinson, H.1
Priebe, W.2
Chaires, J.B.3
Wang, A.H.4
-
71
-
-
0031605324
-
Stability and structure of model DNA triplexes and quadraplexes and their interactions with small ligands
-
Shafer RH. 1998. Stability and structure of model DNA triplexes and quadraplexes and their interactions with small ligands. Prog. Nuceic Acid Res. Mol. Biol. 59: 55-94.
-
(1998)
Prog. Nuceic Acid Res. Mol. Biol.
, vol.59
, pp. 55-94
-
-
Shafer, R.H.1
-
72
-
-
0029996279
-
Drug binding to higher-order DNA structures: Ethidium bromide complexation with parallel quadruple-stranded DNA
-
Shida T, Ikeda N, Sekiguchi J. 1996. Drug binding to higher-order DNA structures: ethidium bromide complexation with parallel quadruple-stranded DNA. Nucleosides Nucleotides 15: 599-605.
-
(1996)
Nucleosides Nucleotides
, vol.15
, pp. 599-605
-
-
Shida, T.1
Ikeda, N.2
Sekiguchi, J.3
-
73
-
-
0029026601
-
Criteria for the mode of binding of DNA binding agents
-
Suh D, Chaires JB. 1995. Criteria for the mode of binding of DNA binding agents. Bioorg. Med. Chem. 3: 723-728.
-
(1995)
Bioorg. Med. Chem.
, vol.3
, pp. 723-728
-
-
Suh, D.1
Chaires, J.B.2
-
74
-
-
0030786928
-
Inhibition of human telomerase by a G-quadraplex-interactive compound
-
Sun D, Thompson B, Gathers BE, Salazar M, Kerwin SM,Trent JO, Jenkins TC, Niedle S, Hurley LH. 1997. Inhibition of human telomerase by a G-quadraplex-interactive compound. J. Med. Chem. 40: 2113-2116.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 2113-2116
-
-
Sun, D.1
Thompson, B.2
Gathers, B.E.3
Salazar, M.4
Kerwin, S.M.5
Trent, J.O.6
Jenkins, T.C.7
Niedle, S.8
Hurley, L.H.9
-
75
-
-
0026465344
-
Substituent position dictates the intercalative DNA-binding mode for anthracene-9,10-dione antitumour drugs
-
Tanious FA, Jenkins TC, Niedle S, Wilson WD. 1992. Substituent position dictates the intercalative DNA-binding mode for anthracene-9,10-dione antitumour drugs. Biochemistry 31: 11632-11640.
-
(1992)
Biochemistry
, vol.31
, pp. 11632-11640
-
-
Tanious, F.A.1
Jenkins, T.C.2
Niedle, S.3
Wilson, W.D.4
-
76
-
-
0032505178
-
Anthracene-9,10-dionesas potential anticancer agents: Bacterial mutation studies of amido-substituted derivatives reveals an unexpected lack of mutagenicity
-
Venitt S, Crofton-Sleigh C, Agbandje M, Jenkins TC, Niedls S. 1998. Anthracene-9,10-dionesas potential anticancer agents: bacterial mutation studies of amido-substituted derivatives reveals an unexpected lack of mutagenicity. J. Med. Chem. 41: 3748-3752.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 3748-3752
-
-
Venitt, S.1
Crofton-Sleigh, C.2
Agbandje, M.3
Jenkins, T.C.4
Niedls, S.5
-
77
-
-
0342987251
-
Design of peptides that bind in the minor groove of DNA at 5′-(A,T)G(A,T)C(A,T)-3′ sequences by a dimeric side-by-side motif
-
Wade WS, Mrksich M, Dervan PB. 1992. Design of peptides that bind in the minor groove of DNA at 5′-(A,T)G(A,T)C(A,T)-3′ sequences by a dimeric side-by-side motif. J. Am. Chem. Soc. 114: 8783-8794.
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 8783-8794
-
-
Wade, W.S.1
Mrksich, M.2
Dervan, P.B.3
-
79
-
-
0031215078
-
On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides
-
White S, Baird EE, Dervan PB. 1997 On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides. Chem. Biol. 4: 569-578.
-
(1997)
Chem. Biol.
, vol.4
, pp. 569-578
-
-
White, S.1
Baird, E.E.2
Dervan, P.B.3
-
80
-
-
0032576722
-
Recognition of four Watson-Crick base pairs in the minor groove by synthetic ligands
-
White S, Szewczyk JW, Turner JM, Baird EE, Dervan PB. 1998. Recognition of four Watson-Crick base pairs in the minor groove by synthetic ligands. Nature 391: 468-471.
-
(1998)
Nature
, vol.391
, pp. 468-471
-
-
White, S.1
Szewczyk, J.W.2
Turner, J.M.3
Baird, E.E.4
Dervan, P.B.5
-
81
-
-
0024787884
-
Monovalent cation-induced structure of telomeric DNA: The G-quartet model
-
Williamson JR, Raghuraman MK, Cech TR. 1989. Monovalent cation-induced structure of telomeric DNA: the G-quartet model. Cell 59: 871-880.
-
(1989)
Cell
, vol.59
, pp. 871-880
-
-
Williamson, J.R.1
Raghuraman, M.K.2
Cech, T.R.3
-
82
-
-
0027451316
-
DNA triple-helix specific intercalators as antigene enhancers - Unfused aromatic cations
-
Wilson WD, Tanious FA, Mizan S, Yao S, Kiselyov AS, Zon G, Strekowski LB. 1993. DNA triple-helix specific intercalators as antigene enhancers - unfused aromatic cations. Biochemistry 32: 10614-10621.
-
(1993)
Biochemistry
, vol.32
, pp. 10614-10621
-
-
Wilson, W.D.1
Tanious, F.A.2
Mizan, S.3
Yao, S.4
Kiselyov, A.S.5
Zon, G.6
Strekowski, L.B.7
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