Energetics of drug-DNA interactions

Biopolymers

Volumn 44, Issue 3, 1997, Pages 201-215

  Chaires, Jonathan B ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Calorimetry; DNA; Drugs; Free energy; Groove binders; Intercalators; Polyelectrolyte effect; Solvent accessible surface area; Thermodynamics

Indexed keywords

BINDING ENERGY; CALORIMETRY; CHEMICAL BONDS; COMPOSITION EFFECTS; CONFORMATIONS; DNA; DRUG PRODUCTS; ESTIMATION; FREE ENERGY; MOLECULAR DYNAMICS; POLYELECTROLYTES; THERMODYNAMICS;

DRUG DNA INTERACTIONS; GROOVE BINDERS; SOLVENT ACCESSIBLE SURFACE AREA;

DRUG INTERACTIONS;

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CONGOCIDINE; DACTINOMYCIN; DAUNORUBICIN; DISTAMYCIN A; DNA; DOXORUBICIN; DRUG; ETHIDIUM BROMIDE; INTERCALATING AGENT; POLYELECTROLYTE; PROPIDIUM IODIDE;

CONFORMATIONAL TRANSITION; DNA DRUG COMPLEX; DRUG CONFORMATION; DRUG DESIGN; DRUG DNA BINDING; DRUG DNA INTERACTION; ENTROPY; GENE TARGETING; HYDROPHOBICITY; LIGAND BINDING; MICROCALORIMETRY; MOLECULAR INTERACTION; REVIEW; THERMODYNAMICS;

BASE SEQUENCE; BINDING SITES; BISBENZIMIDE; DNA; ELECTROLYTES; INTERCALATING AGENTS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PHARMACEUTICAL PREPARATIONS; THERMODYNAMICS;

EID: 4143080522     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0282(1997)44:3<201::AID-BIP2>3.0.CO;2-Z     Document Type: Article

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