Structure-based design of a new bisintercalating anthracycline antibiotic

Journal of Medicinal Chemistry

Volumn 40, Issue 3, 1997, Pages 261-266

  Chaires, Jonathan B ^a   Leng, Fenfei ^a   Przewloka, Teresa ^b   Fokt, Izabela ^b   Ling, Yi He ^b   Perez Soler, Roman ^b   Priebe, Waldemar ^b  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE ANTIBIOTIC AGENT; DOXORUBICIN; INTERCALATING AGENT; UNCLASSIFIED DRUG; WP 631;

ARTICLE; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG DNA BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

ANTIBIOTICS, ANTINEOPLASTIC; CALORIMETRY, DIFFERENTIAL SCANNING; DAUNORUBICIN; DNA; DRUG DESIGN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INTERCALATING AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; NUCLEIC ACID DENATURATION; TEMPERATURE; THERMODYNAMICS; TUMOR CELLS, CULTURED; VISCOSITY;

EID: 0031045487     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9607414     Document Type: Article

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