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Volumn 9, Issue 3, 1999, Pages 305-314

Multistranded DNA structures

Author keywords

[No Author keywords available]

Indexed keywords

CATION; DNA; DOUBLE STRANDED DNA;

EID: 0033150944     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-440X(99)80041-4     Document Type: Article
Times cited : (272)

References (61)
  • 2
    • 0026848846 scopus 로고
    • Human therapeutics based on triple helix technology
    • Chubb JM, Hogan ME: Human therapeutics based on triple helix technology. Trends Biotechnol 1992, 10:132-136.
    • (1992) Trends Biotechnol , vol.10 , pp. 132-136
    • Chubb, J.M.1    Hogan, M.E.2
  • 3
    • 0027080505 scopus 로고
    • Structure and applications of intermolecular DNA triplexes
    • Gee JE, Miller DM: Structure and applications of intermolecular DNA triplexes. Am J Med Sci 1992, 304:366-372.
    • (1992) Am J Med Sci , vol.304 , pp. 366-372
    • Gee, J.E.1    Miller, D.M.2
  • 4
    • 0026349087 scopus 로고
    • The anti-gene strategy: Control of gene expression by triplex-forming-oligonucleotides
    • Hélène C: The anti-gene strategy: Control of gene expression by triplex-forming-oligonucleotides. Anticancer Drug Des 1991, 6:569-584.
    • (1991) Anticancer Drug Des , vol.6 , pp. 569-584
    • Hélène, C.1
  • 7
    • 0000402707 scopus 로고    scopus 로고
    • Structures of nucleic acid triplexes
    • Edited by Neidle S. New York: Oxford University Press
    • Wang E, Feigon J: Structures of nucleic acid triplexes. In Oxford Handbook of Nucleic Acid Structures. Edited by Neidle S. New York: Oxford University Press; 1999:355-388.
    • (1999) Oxford Handbook of Nucleic Acid Structures , pp. 355-388
    • Wang, E.1    Feigon, J.2
  • 8
    • 0017107511 scopus 로고
    • Models of triple-stranded polynucleotides with optimized stereochemistry
    • Arnott S, Bond PJ, Selsing E, Smith PJC: Models of triple-stranded polynucleotides with optimized stereochemistry. Nucleic Acids Res 1976, 3:2459-2470.
    • (1976) Nucleic Acids Res , vol.3 , pp. 2459-2470
    • Arnott, S.1    Bond, P.J.2    Selsing, E.3    Smith, P.J.C.4
  • 12
    • 0001605673 scopus 로고
    • Sugar conformations in intramolecular DNA triplexes determined by coupling constants obtained by automated simulation of P.COSY cross-peaks
    • Macaya RF, Schultze P, Feigon J: Sugar conformations in intramolecular DNA triplexes determined by coupling constants obtained by automated simulation of P.COSY cross-peaks. J Am Chem Soc 1992, 114:781-783.
    • (1992) J Am Chem Soc , vol.114 , pp. 781-783
    • Macaya, R.F.1    Schultze, P.2    Feigon, J.3
  • 16
    • 0032488878 scopus 로고    scopus 로고
    • The contribution of cytosine protonation to the stability of parallel DNA triple helices
    • ;+;•G•C triplets are adjacent or are separated by one or more base pairs, in contrast with previous reports. The position within the helix, rather than the identity of the neighboring base, has the greatest effect on stability.
    • (1998) J Mol Biol , vol.275 , pp. 811-822
    • Asensio, J.L.1    Lane, A.N.2    Dhesi, J.3    Bergqvist, S.4    Brown, T.5
  • 17
    • 0032573199 scopus 로고    scopus 로고
    • Thermodynamic, kinetic, and conformational properties of a parallel intermolecular DNA triplex containing 5′ and 3′ junctions
    • Asensio JL, Dosanjh HS, Jenkins TC, Lane AN: Thermodynamic, kinetic, and conformational properties of a parallel intermolecular DNA triplex containing 5′ and 3′ junctions. Biochemistry 1998, 37:15188-15198. The thermodynamics of a three-stranded DNA triplex containing regions of duplex and triplex are presented. Thermodynamic and kinetic parameters measured by surface plasmon resonance were greatly underestimated when compared to those measured by CS, UV melts and NMR. The structure of the three-stranded molecule is very similar to the structure of the intramolecular triplex formed by a similar sequence.
    • (1998) Biochemistry , vol.37 , pp. 15188-15198
    • Asensio, J.L.1    Dosanjh, H.S.2    Jenkins, T.C.3    Lane, A.N.4
  • 18
    • 0030670937 scopus 로고    scopus 로고
    • Solution conformation of an intramolecular DNA triplex containing a non-nucleotide linker: Comparison with the DNA duplex
    • Bartley JP, Brown T, Lane AN: Solution conformation of an intramolecular DNA triplex containing a non-nucleotide linker: Comparison with the DNA duplex. Biochemistry 1997, 36:14502-14511. This paper describes the solution structure of the parallel YRY triplex formed by the sequence GAGAGA-linker-TCTCTC-linker-CTCTCT and compares the structure to the intramolecular duplex formed by the first two 'strands'. The authors conclude that the structure of the duplex does not change significantly upon binding the third strand, consistent with previous structural studies of DNA triplexes.
    • (1997) Biochemistry , vol.36 , pp. 14502-14511
    • Bartley, J.P.1    Brown, T.2    Lane, A.N.3
  • 19
    • 0032513704 scopus 로고    scopus 로고
    • Solution structure of an intramolecular pyrimidine-purine-pyrimidine triplex containing an RNA third strand
    • Gotfredsen CH, Schultze P, Feigon J: Solution structure of an intramolecular pyrimidine-purine-pyrimidine triplex containing an RNA third strand. J Am Chem Soc 1998, 120:4281-4289. The structure of an intramolecular triplex with an RNA third strand is presented. The structure shows that a triplex with an RNA third strand does not differ significantly from the all-DNA triplex, except for a narrower minor groove. A surprising result is that the RNA sugars are not completely C3′ endo.
    • (1998) J Am Chem Soc , vol.120 , pp. 4281-4289
    • Gotfredsen, C.H.1    Schultze, P.2    Feigon, J.3
  • 20
    • 0032574686 scopus 로고    scopus 로고
    • Solution structure of an intramolecular DNA triplex containing 5-(1-propynyl)-2′-deoxyuridine residues in the third strand
    • Phipps AK, Tarköy M, Schultze P, Feigon J: Solution structure of an intramolecular DNA triplex containing 5-(1-propynyl)-2′-deoxyuridine residues in the third strand. Biochemistry 1998, 37:5820-5830. The authors describe the solution structure of an intramolecular triplex in which the thymines of the third strand are replaced by 5-(1-propynyl)-2′- deoxyuridine. The presence of the modified bases in the third strand changes the triplex structure and explains the increased stability of triplexes with this modification.
    • (1998) Biochemistry , vol.37 , pp. 5820-5830
    • Phipps, A.K.1    Tarköy, M.2    Schultze, P.3    Feigon, J.4
  • 21
    • 0032574794 scopus 로고    scopus 로고
    • Solution structure of an intramolecular DNA triplex linked by hexakis(ethylene glycol) units: d(AGAGAGAA-(EG)6-TTCTCTCT-(EG)6-TCTCTCTT)
    • Tarköy M, Phipps AK, Schultze P, Feigon J: Solution structure of an intramolecular DNA triplex linked by hexakis(ethylene glycol) units: d(AGAGAGAA-(EG)6-TTCTCTCT-(EG)6-TCTCTCTT). Biochemistry 1998, 37:5810-5819. This paper presents the solution structure of an intramolecular DNA triplex with the purine strand sequence AGAGAGAA. The triplex forms an under-wound B-DNA-like helix, with an X displacement intermediate between canonical A- and B-DNA and mostly S-type sugars. It is the basis for a comparison of the modified third-strand structures reported in subsequent papers.
    • (1998) Biochemistry , vol.37 , pp. 5810-5819
    • Tarköy, M.1    Phipps, A.K.2    Schultze, P.3    Feigon, J.4
  • 22
    • 0033555950 scopus 로고    scopus 로고
    • Solution conformation of a parallel DNA triple helix with 5′ and 3′ triplex-duplex junctions
    • Asensio JL, Brown T, Lane AN: Solution conformation of a parallel DNA triple helix with 5′ and 3′ triplex-duplex junctions. Structure 1998, 7:1-11. This paper presents structures of two triplexes containing a 5′ or 3′ duplex-triplex junction. The authors found that the structure of the triplex is unaffected by the position of the junction. Small conformational differences between the duplexes at the 5′ junction versus the 3′ junction are observed.
    • (1998) Structure , vol.7 , pp. 1-11
    • Asensio, J.L.1    Brown, T.2    Lane, A.N.3
  • 24
    • 0028019410 scopus 로고
    • Gene inhibition using antisense oligodeoxynucleotides
    • Wagner RW: Gene inhibition using antisense oligodeoxynucleotides. Nature 1994, 372:333-335.
    • (1994) Nature , vol.372 , pp. 333-335
    • Wagner, R.W.1
  • 25
    • 0027089978 scopus 로고
    • Stability and properties of double and triple helices: Dramatic effects of RNA or DNA backbone composition
    • Roberts RW, Crothers DM: Stability and properties of double and triple helices: Dramatic effects of RNA or DNA backbone composition. Science 1992, 258:1463-1466.
    • (1992) Science , vol.258 , pp. 1463-1466
    • Roberts, R.W.1    Crothers, D.M.2
  • 26
    • 0027168393 scopus 로고
    • Sequence-specific recognition of double helical RNA and RNA-DNA by triple helix formation
    • Han HY, Dervan PB: Sequence-specific recognition of double helical RNA and RNA-DNA by triple helix formation. Proc Natl Acad Sci USA 1993, 90:3806-3810.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3806-3810
    • Han, H.Y.1    Dervan, P.B.2
  • 27
    • 0000058364 scopus 로고
    • Thermodynamics of oligodeoxyribonucleotide-directed triple helix formation: An analysis using quantitative affinity cleavage titration
    • Singleton SF, Dervan PB: Thermodynamics of oligodeoxyribonucleotide-directed triple helix formation: An analysis using quantitative affinity cleavage titration. J Am Chem Soc 1992, 114:6957-6965.
    • (1992) J Am Chem Soc , vol.114 , pp. 6957-6965
    • Singleton, S.F.1    Dervan, P.B.2
  • 28
    • 0028908157 scopus 로고
    • Relative stabilities of triple helices composed of combinations of DNA, RNA and 2′-o-methyl-RNA backbones: Chimeric circular oligonucleotides as probes
    • Wang S, Kool ET: Relative stabilities of triple helices composed of combinations of DNA, RNA and 2′-o-methyl-RNA backbones: Chimeric circular oligonucleotides as probes. Nucleic Acids Res 1995, 23:1157-1164.
    • (1995) Nucleic Acids Res , vol.23 , pp. 1157-1164
    • Wang, S.1    Kool, E.T.2
  • 30
    • 0027093126 scopus 로고
    • Stable triple helices are formed upon binding of RNA oligonucleotides and their 2′-O-methyl derivatives to double-helical DNA
    • Escudé C, Sun JS, Rougée M, Garestier T, Hélène C: Stable triple helices are formed upon binding of RNA oligonucleotides and their 2′-O-methyl derivatives to double-helical DNA. C R Acad Sci III 1992, 315:521-525.
    • (1992) C R Acad Sci III , vol.315 , pp. 521-525
    • Escudé, C.1    Sun, J.S.2    Rougée, M.3    Garestier, T.4    Hélène, C.5
  • 31
    • 0026344866 scopus 로고
    • Triple helical polynucleotidic structures: Sugar conformations determined by FTIR spectroscopy
    • Liquier J, Coffinier P, Firon M, Taillandier E: Triple helical polynucleotidic structures: Sugar conformations determined by FTIR spectroscopy. J Biomol Struct Dyn 1991, 9:437-445.
    • (1991) J Biomol Struct Dyn , vol.9 , pp. 437-445
    • Liquier, J.1    Coffinier, P.2    Firon, M.3    Taillandier, E.4
  • 32
    • 0025649498 scopus 로고
    • Four-stranded nucleic acid structures 25 years later: From guanosine gels to telomere DNA
    • Guschlbauer W, Chantot J-F, Thiele D: Four-stranded nucleic acid structures 25 years later: From guanosine gels to telomere DNA. J Biomol Struct Dyn 1990, 8:491-511.
    • (1990) J Biomol Struct Dyn , vol.8 , pp. 491-511
    • Guschlbauer, W.1    Chantot, J.-F.2    Thiele, D.3
  • 33
    • 0015940022 scopus 로고
    • The structures of polyinosinic acid
    • Thiele D, Guschlbauer W: The structures of polyinosinic acid. Biophysik 1973, 9:261-277.
    • (1973) Biophysik , vol.9 , pp. 261-277
    • Thiele, D.1    Guschlbauer, W.2
  • 34
    • 0016610425 scopus 로고
    • X-ray fiber diffraction and model-building study of polyguanylic acid and polyinosinic acid
    • Zimmerman SB, Cohen GH, Davies DR: X-ray fiber diffraction and model-building study of polyguanylic acid and polyinosinic acid. J Mol Biol 1975, 92:181-192.
    • (1975) J Mol Biol , vol.92 , pp. 181-192
    • Zimmerman, S.B.1    Cohen, G.H.2    Davies, D.R.3
  • 35
    • 0024787884 scopus 로고
    • Monovalent cation-induced structure of telomeric DNA: The G-quartet model
    • Williamson JR, Raghuraman MK, Cech TR: Monovalent cation-induced structure of telomeric DNA: The G-quartet model. Cell 1989, 59:871-880.
    • (1989) Cell , vol.59 , pp. 871-880
    • Williamson, J.R.1    Raghuraman, M.K.2    Cech, T.R.3
  • 37
    • 0002303192 scopus 로고    scopus 로고
    • Quadruplex DNA: Anticancer knot
    • Borman S: Quadruplex DNA: Anticancer knot. Chem Eng News 1998, 76:42-46.
    • (1998) Chem Eng News , vol.76 , pp. 42-46
    • Borman, S.1
  • 39
    • 0025905795 scopus 로고
    • Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome
    • Verkerk AJ, Pieretti M, Sutcliffe JS, Fu YH, Kuhl DP, Pizzuti A, Reiner O, Richards S, Victoria MF, Zhang FP et al.: Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell 1991, 65:905-914.
    • (1991) Cell , vol.65 , pp. 905-914
    • Verkerk, A.J.1    Pieretti, M.2    Sutcliffe, J.S.3    Fu, Y.H.4    Kuhl, D.P.5    Pizzuti, A.6    Reiner, O.7    Richards, S.8    Victoria, M.F.9    Zhang, F.P.10
  • 40
    • 0027467617 scopus 로고
    • Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution
    • Macaya RF, Schultze P, Smith FW, Roe JA, Feigon J: Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution. Proc Natl Acad Sci USA 1993, 90:3745-3749.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3745-3749
    • Macaya, R.F.1    Schultze, P.2    Smith, F.W.3    Roe, J.A.4    Feigon, J.5
  • 41
    • 0032567432 scopus 로고    scopus 로고
    • Structure-activity of tetrad-forming oligonucleotides as a potent anti-HIV therapeutic drug
    • Jing NJ, Hogan ME: Structure-activity of tetrad-forming oligonucleotides as a potent anti-HIV therapeutic drug. J Biol Chem 1998, 273:34992-34999. This paper reports the ion dependence of the structure of an intramolecular G-quadruplex that inhibits HIV integrase. The monovalent cation present in solution changes the structure of the quadruplex. The changes in structure are correlated with a dramatic change in function, highlighting the importance of cations in DNA structure and function.
    • (1998) J Biol Chem , vol.273 , pp. 34992-34999
    • Jing, N.J.1    Hogan, M.E.2
  • 42
    • 0026591751 scopus 로고
    • Crystal structure of four-stranded Oxytricha telomeric DNA
    • Kang C, Zhang X, Ratliff R, Moyzis R, Rich A: Crystal structure of four-stranded Oxytricha telomeric DNA. Nature 1992, 356:126-131.
    • (1992) Nature , vol.356 , pp. 126-131
    • Kang, C.1    Zhang, X.2    Ratliff, R.3    Moyzis, R.4    Rich, A.5
  • 43
    • 0026554887 scopus 로고
    • Quadruplex structure of telomeric DNA oligonucleotides
    • Smith FW, Feigon J: Quadruplex structure of telomeric DNA oligonucleotides. Nature 1992, 356:164-168.
    • (1992) Nature , vol.356 , pp. 164-168
    • Smith, F.W.1    Feigon, J.2
  • 44
    • 0028773155 scopus 로고
    • Refined solution structure of the dimeric quadruplex formed from the Oxytricha telomeric oligonucleotide d(GGGGTTTTGGGG)
    • Schultze P, Smith FW, Feigon J: Refined solution structure of the dimeric quadruplex formed from the Oxytricha telomeric oligonucleotide d(GGGGTTTTGGGG). Structure 1994, 2:221-233.
    • (1994) Structure , vol.2 , pp. 221-233
    • Schultze, P.1    Smith, F.W.2    Feigon, J.3
  • 45
    • 0028850113 scopus 로고
    • 1H NMR spectroscopy of DNA triplexes and quadruplexes
    • Edited by James TL. San Diego: Academic Press
    • 1H NMR spectroscopy of DNA triplexes and quadruplexes. In Methods in Enzymology. Edited by James TL. San Diego: Academic Press; 1995:225-255.
    • (1995) Methods in Enzymology , pp. 225-255
    • Feigon, J.1    Koshlap, K.M.2    Smith, F.W.3
  • 46
    • 0009699185 scopus 로고    scopus 로고
    • DNA triplexes, quadruplexes, and aptamers
    • Edited by Grant DM, Harris RK. West Sussex, England: John Wiley & Sons Ltd.
    • Feigon J: DNA triplexes, quadruplexes, and aptamers. In Encyclopedia of Nuclear Magnetic Resonance. Edited by Grant DM, Harris RK. West Sussex, England: John Wiley & Sons Ltd.; 1996:1726-1731.
    • (1996) Encyclopedia of Nuclear Magnetic Resonance , pp. 1726-1731
    • Feigon, J.1
  • 47
    • 0032566709 scopus 로고    scopus 로고
    • A K cation-induced conformational switch within a loop spanning segment of a DNA quadruplex containing G-G-G-C repeats
    • + form. Significant differences in the structures of the top C•G•C•G quartet and the loops are observed in the presence of the different counterions.
    • (1998) J Mol Biol , vol.282 , pp. 637-652
    • Bouaziz, S.1    Kettani, A.2    Patel, D.J.3
  • 48
    • 0032566629 scopus 로고    scopus 로고
    • Solution structure of a Na cation stabilized DNA quadruplex containing G·G·G·G and G·C·G·C tetrads formed by G-G-G-C repeats observed in adeno-associated viral DNA
    • + counterions. A dimeric quadruplex with two G-quartets and two G•C•G•C quartets connected by T4 loops is formed.
    • (1998) J Mol Biol , vol.282 , pp. 619-636
    • Kettani, A.1    Bouaziz, S.2    Gorin, A.3    Zhao, H.4    Jones, R.A.5    Patel, D.J.6
  • 49
    • 0032126691 scopus 로고    scopus 로고
    • Ammonium ion as an NMR probe for monovalent cation coordination sites of DNA quadruplexes
    • Hud NV, Schultze P, Feigon J: Ammonium ion as an NMR probe for monovalent cation coordination sites of DNA quadruplexes. J Am Chem Soc 1998, 120:6403-6404.
    • (1998) J Am Chem Soc , vol.120 , pp. 6403-6404
    • Hud, N.V.1    Schultze, P.2    Feigon, J.3
  • 50
    • 0033534681 scopus 로고    scopus 로고
    • Binding sites and dynamics of ammonium ions in a telomere repeat DNA quadruplex
    • Hud NV, Schultze P, Sklenar V, Feigon J: Binding sites and dynamics of ammonium ions in a telomere repeat DNA quadruplex. J Mol 1999, 285:233-243. This paper reports the first direct localization of monovalent cations on a nucleic acid in solution, using the ammonium ion. Three ammonium cations are centered between the planes of the four G-quartets. Movement of the ammonium between the G-quartets and into solution was monitored by NMR spectroscopy.
    • (1999) J Mol , vol.285 , pp. 233-243
    • Hud, N.V.1    Schultze, P.2    Sklenar, V.3    Feigon, J.4
  • 51
    • 0029908928 scopus 로고    scopus 로고
    • + in DNA quadruplexes is dominated by relative free energies of hydration - A thermodynamic analysis by H-1 NMR
    • + in DNA quadruplexes is dominated by relative free energies of hydration - A thermodynamic analysis by H-1 NMR. Biochemistry 1996, 35:15383-15390.
    • (1996) Biochemistry , vol.35 , pp. 15383-15390
    • Hud, N.V.1    Smith, F.W.2    Anet, F.A.L.3    Feigon, J.4
  • 53
    • 0031576353 scopus 로고    scopus 로고
    • The crystal structure of a parallel-stranded guanine tetraplex at 0.95 angstrom resolution
    • Phillips K, Dauter Z, Murchie AIH, Lilley DMJ, Luisi B: The crystal structure of a parallel-stranded guanine tetraplex at 0.95 angstrom resolution. J Mol Biol 1997, 273:171-182.
    • (1997) J Mol Biol , vol.273 , pp. 171-182
    • Phillips, K.1    Dauter, Z.2    Murchie, A.I.H.3    Lilley, D.M.J.4    Luisi, B.5
  • 55
    • 0001404315 scopus 로고
    • Molecular structure of helical polycytidylic acid
    • Langridge R, Rich A: Molecular structure of helical polycytidylic acid. Nature 1963, 198:725-728.
    • (1963) Nature , vol.198 , pp. 725-728
    • Langridge, R.1    Rich, A.2
  • 56
    • 0027278767 scopus 로고
    • A tetrameric DNA structure with protonated cytosine.cytosine base pairs
    • Gehring K, Leroy JL, Gueron M: A tetrameric DNA structure with protonated cytosine.cytosine base pairs. Nature 1993, 363:561-565.
    • (1993) Nature , vol.363 , pp. 561-565
    • Gehring, K.1    Leroy, J.L.2    Gueron, M.3
  • 57
    • 0009711974 scopus 로고
    • A new DNA quadruplex
    • Feigon J: A new DNA quadruplex. Curr Biol 1993, 3:611-613.
    • (1993) Curr Biol , vol.3 , pp. 611-613
    • Feigon, J.1
  • 58
    • 0032531972 scopus 로고    scopus 로고
    • Intercalated cytosine motif and novel adenine clusters in the crystal structure of the Tetrahymena telomere
    • +•C base pair. The 5′ adenines form a myriad of A•A base pairs with interesting geometries. The quadruplexes are arranged in a grid pattern in the crystal.
    • (1998) Nucleic Acids Res , vol.26 , pp. 4696-4705
    • Cai, L.1    Chen, L.Q.2    Raghavan, S.3    Ratliff, R.4    Moyzis, R.5    Rich, A.6
  • 60
    • 0031558792 scopus 로고    scopus 로고
    • Centromeric pyrimidine strands fold into an intercalated motif by forming a double hairpin with a novel T·G·G·T tetrad: Solution structure of the d(TCCCGTTTCCA) dimer
    • Gallego J, Chou SH, Reid BR: Centromeric pyrimidine strands fold into an intercalated motif by forming a double hairpin with a novel T·G·G·T tetrad: Solution structure of the d(TCCCGTTTCCA) dimer. J Mol Biol 1997, 273:840-856. This paper shows another interesting variation of the l-motif. Two cytosine-rich hairpins dimerize to form the quadruplex. The 5′ guanine and 3′ thymine in the loops of each hairpin form a novel TGGT tetrad.
    • (1997) J Mol Biol , vol.273 , pp. 840-856
    • Gallego, J.1    Chou, S.H.2    Reid, B.R.3
  • 61
    • 0032557634 scopus 로고    scopus 로고
    • An intramolecular l-motif: The solution structure and base-pair opening kinetics of d(5mCCT(3)CCT(3ACCT(3)CC)
    • Han XG, Leroy JL, Gueron M: An intramolecular l-motif: The solution structure and base-pair opening kinetics of d(5mCCT(3)CCT(3)ACCT(3)CC). J Mol Biol 1998, 278:949-965. The structure of this intramolecular l-motif illustrates the effect of linker sequences on the folding topology and stability of l-motif structures.
    • (1998) J Mol Biol , vol.278 , pp. 949-965
    • Han, X.G.1    Leroy, J.L.2    Gueron, M.3


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