A structural basis for recognition of A·T and T·A base pairs in the minor groove of B-DNA

Science

Volumn 282, Issue 5386, 1998, Pages 111-115

  Kielkopf, Clara L ^a   White, Sarah ^b   Szewczyk, Jason W ^b   Turner, James M ^b   Baird, Eldon E ^b   Dervan, Peter B ^b   Rees, Douglas C ^b  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b California Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; IMIDAZOLE; POLYAMIDE; PYRROLE;

ARTICLE; BASE PAIRING; CRYSTAL STRUCTURE; DNA BINDING; HYDROGEN BOND; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN BINDING; STRUCTURE ANALYSIS;

ADENINE; BASE COMPOSITION; DIMERIZATION; DNA; HYDROGEN BONDING; LIGANDS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; NYLONS; OLIGODEOXYRIBONUCLEOTIDES; THYMINE;

EID: 0032475994     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.282.5386.111     Document Type: Article

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42. We are grateful to the NIH for research support, to the NSF for a predoctoral fellowship to C.L.K., to J. Edward Richter for an undergraduate fellowship to J.M.T., and to the Howard Hughes Medical Institute for a predoctoral fellowship to E.E.B. We thank J. E. Wedekind, C. L. Drennan, T. M. Iverson, and M. Williamson for assistance with data collection and S. Horvath for oligonucleotide synthesis. The rotation camera facility at SSRL is supported by the U.S. Department of Energy and NIH. Coordinates have been deposited in the Nucleic Acid Database with accession numbers BDD002 (ImHpPyPy) and BDD003 (ImPyPyPy).