메뉴 건너뛰기




Volumn 24, Issue 4 I, 1996, Pages 796-801

Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; RIFAMPICIN; VERAPAMIL;

EID: 0029786432     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.1996.v24.pm0008855178     Document Type: Article
Times cited : (275)

References (47)
  • 1
    • 0023588109 scopus 로고
    • Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man
    • Watkins PB, Wrighton SA, Schuetz EG, Molowa DT, Guzelian PS. Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man. J Clin Invest 1987;80:1029-1036.
    • (1987) J Clin Invest , vol.80 , pp. 1029-1036
    • Watkins, P.B.1    Wrighton, S.A.2    Schuetz, E.G.3    Molowa, D.T.4    Guzelian, P.S.5
  • 2
    • 0026464616 scopus 로고
    • Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
    • Kolars JC, Schmiedlin-Ren P, Schuetz JD, Fang C, Watkins PB. Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. J Clin Invest 1992;90:1871-1878.
    • (1992) J Clin Invest , vol.90 , pp. 1871-1878
    • Kolars, J.C.1    Schmiedlin-Ren, P.2    Schuetz, J.D.3    Fang, C.4    Watkins, P.B.5
  • 5
    • 0025344378 scopus 로고
    • Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues
    • De Waziers I, Cugnenc PH, Yang CS, Leroux J-P, Beaune PH. Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues. J Pharmacol Exp Ther 1990; 253:387-394.
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 387-394
    • De Waziers, I.1    Cugnenc, P.H.2    Yang, C.S.3    Leroux, J.-P.4    Beaune, P.H.5
  • 6
    • 0028054999 scopus 로고
    • Extrahepatic metabolism of drugs in humans
    • Krishna DR, Klotz U. Extrahepatic metabolism of drugs in humans. Clin Pharmacokinet 1994;26:144-160.
    • (1994) Clin Pharmacokinet , vol.26 , pp. 144-160
    • Krishna, D.R.1    Klotz, U.2
  • 7
  • 8
    • 0026457407 scopus 로고
    • Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction
    • Hebert MF, Roberts JP, Prueksaritanont T, Benet LZ. Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction. Clin Pharmacol Ther 1992; 52:453-457.
    • (1992) Clin Pharmacol Ther , vol.52 , pp. 453-457
    • Hebert, M.F.1    Roberts, J.P.2    Prueksaritanont, T.3    Benet, L.Z.4
  • 10
    • 0019378948 scopus 로고
    • Superiority of stable isotope techniques in the assessment of the bioavailability of drugs undergoing extensive first pass elimination
    • Eichelbaum M, Dengler HJ, Somogyi A, von Unruh GE. Superiority of stable isotope techniques in the assessment of the bioavailability of drugs undergoing extensive first pass elimination. Eur J Clin Pharmacol 1981; 19:127-131.
    • (1981) Eur J Clin Pharmacol , vol.19 , pp. 127-131
    • Eichelbaum, M.1    Dengler, H.J.2    Somogyi, A.3    Von Unruh, G.E.4
  • 11
    • 0026778218 scopus 로고
    • Predictability of the in vivo metabolism of verapamil from in vitro data: Contribution of individual metabolic pathways and stereoselective aspects
    • Kroemer HK, Echizen H, Heidemann H, Eichelbaum M. Predictability of the in vivo metabolism of verapamil from in vitro data: contribution of individual metabolic pathways and stereoselective aspects. J Pharmacol Exp Ther 1992;260:1052-1057.
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 1052-1057
    • Kroemer, H.K.1    Echizen, H.2    Heidemann, H.3    Eichelbaum, M.4
  • 13
    • 0029591169 scopus 로고
    • Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demethylation of verapamil in humans
    • Busse D, Cosme J, Beaune P, Kroemer HK, Eichelbaum M. Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demethylation of verapamil in humans. Naunyn Schmiedebergs Arch Pharmacol 1995;353:116-121.
    • (1995) Naunyn Schmiedebergs Arch Pharmacol , vol.353 , pp. 116-121
    • Busse, D.1    Cosme, J.2    Beaune, P.3    Kroemer, H.K.4    Eichelbaum, M.5
  • 14
    • 0022196456 scopus 로고
    • The effect of dextro-, levo-, and racemic verapamil on atrioventricular conduction in humans
    • Echizen H, Brecht T, Niedergesäss S, Vogelgesang B, Eichelbaum M. The effect of dextro-, levo-, and racemic verapamil on atrioventricular conduction in humans. Am Heart J 1985;109:210-217.
    • (1985) Am Heart J , vol.109 , pp. 210-217
    • Echizen, H.1    Brecht, T.2    Niedergesäss, S.3    Vogelgesang, B.4    Eichelbaum, M.5
  • 15
    • 0021994845 scopus 로고
    • Effects of d,l-verapamil on atrioventricular conduction in relation to its stereoselective first-pass metabolism
    • Echizen H, Vogelgesang B, Eichelbaum M. Effects of d,l-verapamil on atrioventricular conduction in relation to its stereoselective first-pass metabolism. Clin Pharmacol Ther 1985;38:71-76.
    • (1985) Clin Pharmacol Ther , vol.38 , pp. 71-76
    • Echizen, H.1    Vogelgesang, B.2    Eichelbaum, M.3
  • 18
    • 0021943524 scopus 로고
    • Reduction of bioavailability of verapamil by rifampin
    • Rahn KH, Mooy J, Böhm R, Von de Vet A. Reduction of bioavailability of verapamil by rifampin. N Engl J Med 1985;312:920-921.
    • (1985) N Engl J Med , vol.312 , pp. 920-921
    • Rahn, K.H.1    Mooy, J.2    Böhm, R.3    Von De Vet, A.4
  • 19
    • 0021848458 scopus 로고
    • Verapamil-rifampin interaction
    • Barbarash RA. Verapamil-rifampin interaction. Drug Intell Clin Pharm 1985;19:559-560.
    • (1985) Drug Intell Clin Pharm , vol.19 , pp. 559-560
    • Barbarash, R.A.1
  • 21
    • 0027256704 scopus 로고
    • Simultaneous assessment of the intravenous and oral disposition of the enantiomers of racemic nimodipine by chiral stationary-phase high-performance liquid chromatography and gas chromatography/mass spectroscopy combined with a stable isotope technique
    • Fischer C, Schönberger F, Muck W, Heuck K, Eichelbaum M. Simultaneous assessment of the intravenous and oral disposition of the enantiomers of racemic nimodipine by chiral stationary-phase high-performance liquid chromatography and gas chromatography/mass spectroscopy combined with a stable isotope technique. J Pharm Sci 1993;82:244-250.
    • (1993) J Pharm Sci , vol.82 , pp. 244-250
    • Fischer, C.1    Schönberger, F.2    Muck, W.3    Heuck, K.4    Eichelbaum, M.5
  • 22
    • 0025280062 scopus 로고
    • Interaction of verapamil and cimetidine: Stereochemical aspects of drug metabolism, drug disposition and drug action
    • Mikus G, Eichelbaum M, Fischer C, Gumulka S, Klotz U, Kroemer HK. Interaction of verapamil and cimetidine: stereochemical aspects of drug metabolism, drug disposition and drug action. J Pharmacol Exp Ther 1990; 253:1042-1048.
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 1042-1048
    • Mikus, G.1    Eichelbaum, M.2    Fischer, C.3    Gumulka, S.4    Klotz, U.5    Kroemer, H.K.6
  • 26
    • 0019507408 scopus 로고
    • Pharmacokinetics, bioavailability and ECG response of verapamil in patients with liver cirrhosis
    • Somogyi A, Albrecht M, Kliems G, Schäfer K, Eichelbaum M. Pharmacokinetics, bioavailability and ECG response of verapamil in patients with liver cirrhosis. Br J Clin Pharmacol 1981;12:51-60.
    • (1981) Br J Clin Pharmacol , vol.12 , pp. 51-60
    • Somogyi, A.1    Albrecht, M.2    Kliems, G.3    Schäfer, K.4    Eichelbaum, M.5
  • 27
    • 0024204468 scopus 로고
    • Stereoselective protein binding of verapamil enantiomers
    • Gross AS, Heuer B, Eichelbaum M. Stereoselective protein binding of verapamil enantiomers. Biochem Pharmacol 1988;37:4623-4627.
    • (1988) Biochem Pharmacol , vol.37 , pp. 4623-4627
    • Gross, A.S.1    Heuer, B.2    Eichelbaum, M.3
  • 29
  • 30
    • 0022466745 scopus 로고
    • Changes in antipyrine and indocyanine green kinetics during nifedipine, verapamil, and diltiazem therapy
    • Bauer LA, Stenwall M, Horn JR, Davis R, Opheim K, Greene L. Changes in antipyrine and indocyanine green kinetics during nifedipine, verapamil, and diltiazem therapy. Clin Pharmacol Ther 1986;40:239-242.
    • (1986) Clin Pharmacol Ther , vol.40 , pp. 239-242
    • Bauer, L.A.1    Stenwall, M.2    Horn, J.R.3    Davis, R.4    Opheim, K.5    Greene, L.6
  • 32
    • 0025272882 scopus 로고
    • The value of Doppler US in the study of hepatic hemodynamics. Consensus conference
    • Bolondi L. The value of Doppler US in the study of hepatic hemodynamics. Consensus conference. J Hepatol 1990;10:353-355.
    • (1990) J Hepatol , vol.10 , pp. 353-355
    • Bolondi, L.1
  • 34
    • 0026782943 scopus 로고
    • Induction of cytochrome P450IA genes (CYP1A) by omeprazole in the human alimentary tract
    • McDonnell WM, Scheiman JM, Traber PG. Induction of cytochrome P450IA genes (CYP1A) by omeprazole in the human alimentary tract. Gastroenterology 1992;103:1509-1516.
    • (1992) Gastroenterology , vol.103 , pp. 1509-1516
    • McDonnell, W.M.1    Scheiman, J.M.2    Traber, P.G.3
  • 36
    • 0028590127 scopus 로고
    • Biochemistry and molecular biology of the human CYP2C subfamily
    • Goldstein JA, de Morais SMF. Biochemistry and molecular biology of the human CYP2C subfamily. Pharmacogenetics 1994;4:285-299.
    • (1994) Pharmacogenetics , vol.4 , pp. 285-299
    • Goldstein, J.A.1    De Morais, S.M.F.2
  • 37
    • 0022347031 scopus 로고
    • Pharmacokinetics of oral and intravenous rifampicin during chronic administration
    • Loos U, Musch E, Jensen JC, Mikus G, Schwabe HK, Eichelbaum M. Pharmacokinetics of oral and intravenous rifampicin during chronic administration. Klin Wschr 1985;63:1205-1211.
    • (1985) Klin Wschr , vol.63 , pp. 1205-1211
    • Loos, U.1    Musch, E.2    Jensen, J.C.3    Mikus, G.4    Schwabe, H.K.5    Eichelbaum, M.6
  • 38
    • 0029055363 scopus 로고
    • Disposition of intravenous and oral cyclosporine after administration with grapefruit juice
    • Ducharme MP, Warbasse LH, Edwards DJ. Disposition of intravenous and oral cyclosporine after administration with grapefruit juice. Clin Pharmacol Ther 1995;57:485-491.
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 485-491
    • Ducharme, M.P.1    Warbasse, L.H.2    Edwards, D.J.3
  • 40
    • 0019381325 scopus 로고
    • Simultaneous determination of the intravenous and oral pharmacokinetic parameters of D,L-verapamil using stable isotope-labelled verapamil
    • Eichelbaum M, Somogyi A, Unruh GEv, Dengler HJ. Simultaneous determination of the intravenous and oral pharmacokinetic parameters of D,L-verapamil using stable isotope-labelled verapamil. Eur J Clin Pharmacol 1981;19:133-137.
    • (1981) Eur J Clin Pharmacol , vol.19 , pp. 133-137
    • Eichelbaum, M.1    Somogyi, A.2    Unruh, G.Ev.3    Dengler, H.J.4
  • 41
    • 0019418012 scopus 로고
    • Direct determination of hepatic extraction of verapamil in cardiac patients
    • Woodcock BG, Schulz W, Kober G, Rietbrock N. Direct determination of hepatic extraction of verapamil in cardiac patients. Clin Pharmacol Ther 1981;30:52-56.
    • (1981) Clin Pharmacol Ther , vol.30 , pp. 52-56
    • Woodcock, B.G.1    Schulz, W.2    Kober, G.3    Rietbrock, N.4
  • 42
    • 0019085745 scopus 로고
    • Influence of mesocaval shunt surgery on verapamil kinetics, bioavailability and response
    • Eichelbaum M, Albrecht M, Kliems G, Schäfer K, Somogyi A. Influence of mesocaval shunt surgery on verapamil kinetics, bioavailability and response. Brit J Clin Pharmacol 1980;10:527-530.
    • (1980) Brit J Clin Pharmacol , vol.10 , pp. 527-530
    • Eichelbaum, M.1    Albrecht, M.2    Kliems, G.3    Schäfer, K.4    Somogyi, A.5
  • 43
    • 0027523333 scopus 로고
    • Nonchiral, homochiral and composite chiral drugs
    • Ariens EJ. Nonchiral, homochiral and composite chiral drugs. Trends Pharmacol Sci 1993;14:68-75.
    • (1993) Trends Pharmacol Sci , vol.14 , pp. 68-75
    • Ariens, E.J.1
  • 44
    • 0028295436 scopus 로고
    • An enantiomer-enantiomer interaction of (S)- and (R)-propafenone modifies the effect of racemic drug therapy
    • Kroemer HK, Fromm MF, Bühl K, Terefe H, Blaschke G, Eichelbaum M. An enantiomer-enantiomer interaction of (S)- and (R)-propafenone modifies the effect of racemic drug therapy. Circulation 1994;89:2396-2400.
    • (1994) Circulation , vol.89 , pp. 2396-2400
    • Kroemer, H.K.1    Fromm, M.F.2    Bühl, K.3    Terefe, H.4    Blaschke, G.5    Eichelbaum, M.6
  • 45
    • 0025786589 scopus 로고
    • Age-dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampicin
    • Smith DA, Chandler MHH, Shedlofsky SI, Wedlund PJ, Blouin RA. Age-dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampicin. Br J Clin Pharmacol 1991;32:735-739.
    • (1991) Br J Clin Pharmacol , vol.32 , pp. 735-739
    • Smith, D.A.1    Chandler, M.H.H.2    Shedlofsky, S.I.3    Wedlund, P.J.4    Blouin, R.A.5
  • 46
    • 0024535104 scopus 로고
    • Urinary excretion of 6β-hydroxycortisol and the time course measurement of enzyme induction in man
    • Ohnhaus EE, Breckenridge AM, Park BK. Urinary excretion of 6β-hydroxycortisol and the time course measurement of enzyme induction in man. Eur J Clin Pharmacol 1989;36:39-46.
    • (1989) Eur J Clin Pharmacol , vol.36 , pp. 39-46
    • Ohnhaus, E.E.1    Breckenridge, A.M.2    Park, B.K.3
  • 47
    • 0027050416 scopus 로고
    • Effect of corticosteroids on the expression of cytochromes P450 and on cyclosporin A oxidase activity in primary cultures of human hepatocytes
    • Pichard L, Fabre I, Daujat M, Domergue J, Joyeux H, Maurel P. Effect of corticosteroids on the expression of cytochromes P450 and on cyclosporin A oxidase activity in primary cultures of human hepatocytes. Mol Pharmacol 1992;41:1047-1055.
    • (1992) Mol Pharmacol , vol.41 , pp. 1047-1055
    • Pichard, L.1    Fabre, I.2    Daujat, M.3    Domergue, J.4    Joyeux, H.5    Maurel, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.