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Volumn 36, Issue 4, 1996, Pages 356-360

Effects of atorvastatin, an HMG-CoA reductase inhibitor, on hepatic oxidative metabolism of antipyrine

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYPHENAZONE; ATORVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NORPHENAZONE; PHENAZONE;

EID: 0029995258     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1552-4604.1996.tb04212.x     Document Type: Article
Times cited : (18)

References (18)
  • 1
    • 0022549920 scopus 로고
    • A receptor-mediated pathway for cholesterol homeostasis
    • Brown MS, Goldstein JL: A receptor-mediated pathway for cholesterol homeostasis. Science 1986;232:34-47.
    • (1986) Science , vol.232 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 2
    • 0029043903 scopus 로고
    • Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor
    • Nawrocki JW, Weiss SR, Davidson MH, Sprecher DL, Schwartz SL, Lupien P-J, et al: Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor. Arterioscler Thromb Vasc Biol 1995;15:678-682.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 678-682
    • Nawrocki, J.W.1    Weiss, S.R.2    Davidson, M.H.3    Sprecher, D.L.4    Schwartz, S.L.5    Lupien, P.-J.6
  • 3
    • 0026567257 scopus 로고
    • Hepatic and nonhepatic sterol synthesis and tissue distribution following administration of a liver selective HMG-CoA reductase inhibitor, CI-981: Comparison with selective HMG-CoA reductase inhibitors
    • Bocan TMA, Ferguson E, McNally W, Uhlendorf PD, Mueller SB, Dehart P, et al: Hepatic and nonhepatic sterol synthesis and tissue distribution following administration of a liver selective HMG-CoA reductase inhibitor, CI-981: comparison with selective HMG-CoA reductase inhibitors. Biochim Biophys Acta 1992;1123: 133-144.
    • (1992) Biochim Biophys Acta , vol.1123 , pp. 133-144
    • Bocan, T.M.A.1    Ferguson, E.2    McNally, W.3    Uhlendorf, P.D.4    Mueller, S.B.5    Dehart, P.6
  • 4
    • 0018575509 scopus 로고
    • The antipyrine test in clinical pharmacology: Conceptions and misconceptions
    • Vesell ES: The antipyrine test in clinical pharmacology: Conceptions and misconceptions. Clin Pharmacol Ther 1979;26:275-286.
    • (1979) Clin Pharmacol Ther , vol.26 , pp. 275-286
    • Vesell, E.S.1
  • 5
    • 0023892496 scopus 로고
    • Antipyrine as a model drug to study hepatic drug-metabolizing capacity
    • Poulsen HE, Loft S: Antipyrine as a model drug to study hepatic drug-metabolizing capacity. J Hepatol 1988;6:374-382.
    • (1988) J Hepatol , vol.6 , pp. 374-382
    • Poulsen, H.E.1    Loft, S.2
  • 6
    • 0026094695 scopus 로고
    • Drugs and the liver. II. The role of the antipyrine test in drug metabolism studies
    • Hartleb M: Drugs and the liver. II. The role of the antipyrine test in drug metabolism studies. Biopharm Drug Dispos 1991;12: 559-570.
    • (1991) Biopharm Drug Dispos , vol.12 , pp. 559-570
    • Hartleb, M.1
  • 7
    • 0023876839 scopus 로고
    • HMG-CoA reductase inhibitors for treatment of hypercholesterolemia
    • Grundy SM: HMG-CoA reductase inhibitors for treatment of hypercholesterolemia. N Engl J Med 1988;319:24-33.
    • (1988) N Engl J Med , vol.319 , pp. 24-33
    • Grundy, S.M.1
  • 8
    • 0026719974 scopus 로고
    • Pravastatin: A new drug for the treatment of hypercholesterolemia
    • Jungnickel PW, Cantral KA, Maloley PA: Pravastatin: a new drug for the treatment of hypercholesterolemia. Clin Pharm 1992;11:677-689.
    • (1992) Clin Pharm , vol.11 , pp. 677-689
    • Jungnickel, P.W.1    Cantral, K.A.2    Maloley, P.A.3
  • 10
    • 0023615056 scopus 로고
    • A comparison of the two one-sided tests procedure and the power approach for assessing the equivalency of average bioavailability
    • Schuirmann DJ: A comparison of the two one-sided tests procedure and the power approach for assessing the equivalency of average bioavailability. J Pharmacokinet Biopharm 1987;15:657-680.
    • (1987) J Pharmacokinet Biopharm , vol.15 , pp. 657-680
    • Schuirmann, D.J.1
  • 11
    • 0019454038 scopus 로고
    • Influence of the genetically controlled deficiency in debrisoquine hydroxylation on antipyrine metabolite formation
    • Danhof M, Idle JR, Teunissen MWE, Sloan TP, Breimer DD, Smith RL: Influence of the genetically controlled deficiency in debrisoquine hydroxylation on antipyrine metabolite formation. Pharmacology 1981;22:349-358.
    • (1981) Pharmacology , vol.22 , pp. 349-358
    • Danhof, M.1    Idle, J.R.2    Teunissen, M.W.E.3    Sloan, T.P.4    Breimer, D.D.5    Smith, R.L.6
  • 14
    • 0022377740 scopus 로고
    • Antipyrine metabolite kinetics in healthy human volunteers during multiple dosing of phenytoin and carbamazepine
    • Shaw PN, Houston JB, Rowland M, Hopkins K, Thiercelin JF, Morselli PL: Antipyrine metabolite kinetics in healthy human volunteers during multiple dosing of phenytoin and carbamazepine. Br J Clin Pharmacol 1985;20:611-618.
    • (1985) Br J Clin Pharmacol , vol.20 , pp. 611-618
    • Shaw, P.N.1    Houston, J.B.2    Rowland, M.3    Hopkins, K.4    Thiercelin, J.F.5    Morselli, P.L.6
  • 15
    • 0022256401 scopus 로고
    • Correlation between antipyrine metabolite formation and theophylline metabolism in humans after simultaneous single-dose administration and at steady state
    • Teunissen MWE, De Leede LGJ, Boeijinga JK, Breimer DD: Correlation between antipyrine metabolite formation and theophylline metabolism in humans after simultaneous single-dose administration and at steady state. J Pharmacol Exp Ther 1985;233: 770-775.
    • (1985) J Pharmacol Exp Ther , vol.233 , pp. 770-775
    • Teunissen, M.W.E.1    De Leede, L.G.J.2    Boeijinga, J.K.3    Breimer, D.D.4
  • 16
    • 0010219641 scopus 로고
    • Identification of cytochrome P450 enzymes involved in the metabolism of antipyrine: Potential and limitations of different in vitro techniques
    • Engel G, Hofmann U, Heidemann H, Eichelbaum M. Identification of cytochrome P450 enzymes involved in the metabolism of antipyrine: potential and limitations of different in vitro techniques (abstract). Naunyn Schmiedebergs Arch Pharmacol 1994;349(suppl):R133.
    • (1994) Naunyn Schmiedebergs Arch Pharmacol , vol.349 , Issue.SUPPL.
    • Engel, G.1    Hofmann, U.2    Heidemann, H.3    Eichelbaum, M.4
  • 17
    • 85035159572 scopus 로고    scopus 로고
    • Antipyrine as a probe for human oxidative drug metabolism: Identification of the cytochrome p450 enzymes catalyzing 4-hydroxy-3-hydroxymethyl- and norantipyrine formation
    • in press
    • Engel G, Hofmann U, Heidemann H, Cosme J, Eichelbaum M: Antipyrine as a probe for human oxidative drug metabolism: identification of the cytochrome p450 enzymes catalyzing 4-hydroxy-3-hydroxymethyl- and norantipyrine formation. Clin Pharmacol Ther (in press)
    • Clin Pharmacol Ther
    • Engel, G.1    Hofmann, U.2    Heidemann, H.3    Cosme, J.4    Eichelbaum, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.