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Volumn 27, Issue 8, 1999, Pages 916-923

Metabolism and excretion of atorvastatin in rats and dogs

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ATORVASTATIN;

EID: 0032791745     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (86)

References (18)
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    • (1998) Drug Metab Dispos , vol.26 , pp. 755-763
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    • Hepatic and nonhepatic sterol synthesis and tissue distribution following administration of a liver selective HMG-CoA reductase inhibitor. CI-981: Comparison with selected HMG-CoA reductase inhibitors
    • Bocan TMA, Ferguson E, McNally W, Uhlendorf PD, Bak Mueller S, DeHart P, Sliskovic DR, Roth BD, Krause BR and Newton RS (1992) Hepatic and nonhepatic sterol synthesis and tissue distribution following administration of a liver selective HMG-CoA reductase inhibitor. CI-981: Comparison with selected HMG-CoA reductase inhibitors. Biochim Biophys Acta 1123:133-144.
    • (1992) Biochim Biophys Acta , vol.1123 , pp. 133-144
    • Bocan, T.M.A.1    Ferguson, E.2    McNally, W.3    Uhlendorf, P.D.4    Bak Mueller, S.5    DeHart, P.6    Sliskovic, D.R.7    Roth, B.D.8    Krause, B.R.9    Newton, R.S.10
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    • 0029957678 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors
    • Desager J-P and Horsmans Y (1996) Clinical pharmacokinetics of 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors. Clin Phamacokinet 5:348-371.
    • (1996) Clin Phamacokinet , vol.5 , pp. 348-371
    • Desager, J.-P.1    Horsmans, Y.2
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    • 0024994209 scopus 로고
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    • Biotransformation of lovastatin V: Species differences in in vivo metabolite profiles in mouse, rat, dog, and human
    • Halpin RA, Ulm EH, Till AE, Kari PH, Vyas LP, Hunninghake DB and Duggan DE (1993) Biotransformation of lovastatin V: Species differences in in vivo metabolite profiles in mouse, rat, dog, and human. Drug Metab Dispos 21:1003-1011.
    • (1993) Drug Metab Dispos , vol.21 , pp. 1003-1011
    • Halpin, R.A.1    Ulm, E.H.2    Till, A.E.3    Kari, P.H.4    Vyas, L.P.5    Hunninghake, D.B.6    Duggan, D.E.7
  • 9
    • 0345586995 scopus 로고
    • Identification of metabolites of CI-981 atorvastatin in rat bile using tandem mass spectrometry and a stable isotope tracer
    • May 29-Jun 3, Chicago, IL. Elsevier Science Inc.
    • Hayes RN, Black A, Hicks JL and Woolf TF (1994) Identification of metabolites of CI-981 atorvastatin) in rat bile using tandem mass spectrometry and a stable isotope tracer (Abstract). 42nd ASMS Conference on Mass Spectroscopy and Allied Topics; 1994 May 29-Jun 3, Chicago, IL. Elsevier Science Inc. 53.
    • (1994) 42nd ASMS Conference on Mass Spectroscopy and Allied Topics , vol.1994 , pp. 53
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    • Roth BD, Blankley CJ, Chucholowski AW, Ferguson E, Hoefle ML, Ortwine DL, Newton RS, Sekerke CS, Sliskovic DR, Stratton CD and Wilson MW (1991) Inhibitors of cholesterol biosynthesis. 3. Tetrahydro-4-hydroxy-6-[(1H-pyrrol-1-y1)ethyl)-2H-pyran-2-one inhibitors of HMC-CoA reductase. 2. Effects of introducing substituents as positions three and four of the pyrrole nucleus. J Med Chem 34:357-366.
    • (1991) J Med Chem , vol.34 , pp. 357-366
    • Roth, B.D.1    Blankley, C.J.2    Chucholowski, A.W.3    Ferguson, E.4    Hoefle, M.L.5    Ortwine, D.L.6    Newton, R.S.7    Sekerke, C.S.8    Sliskovic, D.R.9    Stratton, C.D.10    Wilson, M.W.11
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.