-
1
-
-
0029043903
-
Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-Coa reductase inhibitor
-
Nawrocki JW, Weiss SR, Davidson MH, Sprecher DL, Schwartz SL, Lupien P-J, et al: Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor. Arterioscler Thromb Vasc Biol 1995;15:678-682.
-
(1995)
Arterioscler Thromb Vasc Biol
, vol.15
, pp. 678-682
-
-
Nawrocki, J.W.1
Weiss, S.R.2
Davidson, M.H.3
Sprecher, D.L.4
Schwartz, S.L.5
Lupien, P.-J.6
-
2
-
-
0002410513
-
In vitro and in vivo metabolism of atorvastatin (CI-981)
-
Bethesda, MD: International Society for the Study of Xenobiotics
-
Michniewicz BM, Black AE, Sinz MW, Woolf TF: In vitro and in vivo metabolism of atorvastatin (CI-981) (abstract). In, Proceedings of the Sixth North American ISSX Meeting, Raleigh, NC, October 23-27, 1994. Bethesda, MD: International Society for the Study of Xenobiotics, 1994;93.
-
(1994)
Proceedings of the Sixth North American ISSX Meeting, Raleigh, NC, October 23-27, 1994
, pp. 93
-
-
Michniewicz, B.M.1
Black, A.E.2
Sinz, M.W.3
Woolf, T.F.4
-
3
-
-
0027168405
-
Oxidation of the antihistaminic drug terfenadine in human liver microsomes: Roles of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation
-
Yun C-H, Okerholm RA, Guengerich FP: Oxidation of the antihistaminic drug terfenadine in human liver microsomes: roles of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation. Drug Metab Dispos 1993;21:403-409.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 403-409
-
-
Yun, C.-H.1
Okerholm, R.A.2
Guengerich, F.P.3
-
6
-
-
0027468346
-
Terfenadine-ketoconazole interaction: Pharmacokinetic and electrocardiographic consequences
-
Honig PK, Wortham DC, Zamani K, Conner DP, Mulin JC, Cantilena LR: Terfenadine-ketoconazole interaction: pharmacokinetic and electrocardiographic consequences. JAMA 1993;269: 1513-1518.
-
(1993)
JAMA
, vol.269
, pp. 1513-1518
-
-
Honig, P.K.1
Wortham, D.C.2
Zamani, K.3
Conner, D.P.4
Mulin, J.C.5
Cantilena, L.R.6
-
7
-
-
0000637446
-
Pharmacokinetic interaction between terfenadine and ketoconazole
-
Eller MG, Okerholm RA: Pharmacokinetic interaction between terfenadine and ketoconazole (abstract). Clin Pharmacol Ther 1991;49:130.
-
(1991)
Clin Pharmacol Ther
, vol.49
, pp. 130
-
-
Eller, M.G.1
Okerholm, R.A.2
-
8
-
-
0027768575
-
Itraconazole affects single-dose terfenadine pharmacokinetics and cardiac repolarization pharmacodynamics
-
Honig PK, Wortham DC, Hull R, Zamani K, Smith JE, Cantilena LR: Itraconazole affects single-dose terfenadine pharmacokinetics and cardiac repolarization pharmacodynamics. J Clin Pharmacol 1993;33:1201-1206.
-
(1993)
J Clin Pharmacol
, vol.33
, pp. 1201-1206
-
-
Honig, P.K.1
Wortham, D.C.2
Hull, R.3
Zamani, K.4
Smith, J.E.5
Cantilena, L.R.6
-
9
-
-
0026671408
-
Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin
-
Honig PK, Woosley RL, Zamani K, Conner DP, Cantilena LR: Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin. Clin Pharmacol Ther 1992;52:231-238.
-
(1992)
Clin Pharmacol Ther
, vol.52
, pp. 231-238
-
-
Honig, P.K.1
Woosley, R.L.2
Zamani, K.3
Conner, D.P.4
Cantilena, L.R.5
-
10
-
-
0029879317
-
Grapefruit juice alters the systemic bioavailability and cardiac repolarization of terfenadine in poor metabolizers of terfenadine
-
Honig PK, Wortham DC, Lazarev A, Cantilena LR: Grapefruit juice alters the systemic bioavailability and cardiac repolarization of terfenadine in poor metabolizers of terfenadine. J Clin Pharmacol 1996;36:345-351.
-
(1996)
J Clin Pharmacol
, vol.36
, pp. 345-351
-
-
Honig, P.K.1
Wortham, D.C.2
Lazarev, A.3
Cantilena, L.R.4
-
11
-
-
0030012246
-
Grapefruit juice alters terfenadine pharmacokinetics, resulting in prolongation of repolarization on the electrocardiogram
-
Benton RE, Honig PK, Zamani K, Cantilena LR, Woosley RL: Grapefruit juice alters terfenadine pharmacokinetics, resulting in prolongation of repolarization on the electrocardiogram. Clin Pharmacol Ther 1996;59:383-388.
-
(1996)
Clin Pharmacol Ther
, vol.59
, pp. 383-388
-
-
Benton, R.E.1
Honig, P.K.2
Zamani, K.3
Cantilena, L.R.4
Woosley, R.L.5
-
12
-
-
0027231225
-
The effect of fluconazole on the steady-state pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine in humans
-
Honig PK, Wortham DC, Zamani K, Mullin JC, Conner DP, Cantilena LR: The effect of fluconazole on the steady-state pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine in humans. Clin Pharmacol Ther 1993;53:630-636.
-
(1993)
Clin Pharmacol Ther
, vol.53
, pp. 630-636
-
-
Honig, P.K.1
Wortham, D.C.2
Zamani, K.3
Mullin, J.C.4
Conner, D.P.5
Cantilena, L.R.6
-
13
-
-
0028568568
-
In vitro prediction of the terfenadine-ketoconazole pharmacokinetic interaction
-
von Moltke LL, Greenblatt DJ, Duan SX, Harmatz JS, Shader RI: In vitro prediction of the terfenadine-ketoconazole pharmacokinetic interaction. J Clin Pharmacol 1994;34:1222-1227.
-
(1994)
J Clin Pharmacol
, vol.34
, pp. 1222-1227
-
-
Von Moltke, L.L.1
Greenblatt, D.J.2
Duan, S.X.3
Harmatz, J.S.4
Shader, R.I.5
-
14
-
-
0029028792
-
Overlapping substrate specificities and tissue distribution of Cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
-
Wacher VJ, Wu C-Y, Benet LZ: Overlapping substrate specificities and tissue distribution of Cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy. Mol Carcinogenesis 1995;13:129-134.
-
(1995)
Mol Carcinogenesis
, vol.13
, pp. 129-134
-
-
Wacher, V.J.1
Wu, C.-Y.2
Benet, L.Z.3
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