Apoptosis in Yeasts

IUBMB Life

Volumn 55, Issue 8, 2003, Pages 467-472

  Weinberger, Martin ^a   Ramachandran, Lakshmi ^a   Burhans, William C ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Apoptosis; DNA damage; Metacaspase; S. cerevisiae; S. pombe; Yeast

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE INHIBITOR; CELL CYCLE PROTEIN; DNA FRAGMENT; HIGH MOBILITY GROUP B1 PROTEIN; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN CDC48; PROTEIN CDC48P; PROTEIN P53; UNCLASSIFIED DRUG;

APOPTOSIS; CANCER THERAPY; CELL CYCLE; DNA DAMAGE; ENZYME ACTIVITY; FUNGAL GENETICS; GENE OVEREXPRESSION; MITOSIS; MOLECULAR MODEL; NONHUMAN; PROTEIN FAMILY; REVIEW; RNA STABILITY; YEAST;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL CYCLE; DNA DAMAGE; GENES, FUNGAL; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; YEASTS;

METAZOA;

EID: 0142213317     PISSN: 15216543     EISSN: None     Source Type: Journal    
DOI: 10.1080/15216540310001612336     Document Type: Review

References (53)

1. Madeo, F., Herker, E., Maldener, C., Wissing, S., Lachelt, S., Herlan, M., Fehr, M., Lauber, K., Sigrist, S. J., Wesselborg, S., et al. (2002) A caspase-related protease regulates apoptosis in yeast. Mol. Cell 9, 1-120.
2. Uren, A. G., O'Rourke, K., Aravind, L. A., Pisabarro, M. T., Seshagiri, S., Koonin, E. V., and Dixit, V. M. (2000) Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma. Mol. Cell 6, 961-967.
3. Szallies, A., Kubata, B. K., and Duszenko, M. (2002) A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiae. FEBS Lett. 517, 144-150.
4. Jin, C., and Reed, J. C. (2002) Yeast and apoptosis. Nat. Rev. Mol. Cell Biol. 3, 453-459.
5. Matsuyama, S., Nouraini, S., and Reed, J. C. (1999) Yeast as a tool for apoptosis research. Curr. Opin. Microbiol. 2, 618-623.
6. Ligr, M., Madeo, F., Frohlich, E., Hilt, W., Frohlich, K. U., and Wolf, D. H. (1998) Mammalian Bax triggers apoptotic changes in yeast. FEBS Lett. 438, 61-65.
7. Ink, B., Zornig, M., Baum, B., Hajibagheri, N., James, C., Chittenden, T., and Evan, G. (1997) Human Bak induces cell death in Schizosaccharomyces pombe with morphological changes similar to those with apoptosis in mammalian cells. Mol. Cell Biol. 17, 2468-2474.
8. Madeo, F., Frohlich, E., Ligr, M., Grey, M., Sigrist, S. J., Wolf, D. H., and Frohlich, K. U. (1999) Oxygen stress: a regulator of apoptosis in yeast. J. Cell Biol. 145, 757-767.
9. Madeo, F., Frohlich, E., and Frohlich, K. U. (1997) A yeast mutant showing diagnostic markers of early and late apoptosis. J. Cell Biol. 139, 729-734.
10. Mazzoni, C., Mancini, P., Verdone, L., Madeo, F., Serafini, A., Herker, E., and Falcone, C. (2003) A truncated form of KILsm4p and the absence of factors involved in mRNA decapping trigger apoptosis in yeast. Mol. Biol. Cell 14, 721-729.
11. Shirogane, T., Fukada, T., Muller, J. M., Shima, D. T., Hibi, M., and Hirano, T. (1999) Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis. Immunity 11, 709-719.
12. Xiang, J., Chao, D. T., and Korsmeyer, S. J. (1996) BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases. Proc. Natl. Acad. Sci. USA 93, 14559-14563.
13. Camougrand, N., Grelaud-Coq, A., Marza, E., Priault, M., Bessoule, J. J., and Manon, S. (2003) The product of the UTH1 gene, required for Bax-induced cell death in yeast, is involved in the response to rapamycin. Mol. Microbiol. 47, 495-506.
14. Ludovico, P., Sousa, M. J., Silva, M. T., Leao, C., and Corte-Real, M. (2001) Saccharomyces cerevisiae commits to a programmed cell death process in response to acetic acid. Microbiology, 147, 2409-2415.
15. Severin, F. F., and Hyman, A. A. (2002) Pheromone induces programmed cell death in S. cerevisiae. Curr. Biol. 12, R233-235.
16. Ludovico, P., Rodrigues, F., Almeida, A., Silva, M. T., Barrientos, A., and Corte-Real, M. (2002) Cytochrome c release and mitochondria involvement in programmed cell death induced by acetic acid in Saccharomyces cerevisiae. Mol. Biol. Cell 13, 2598-2606.
17. Yamaki, M., Umehara, T., Chimura, T., and Horikoshi, M. (2001) Cell death with predominant apoptotic features in Saccharomyces cerevisiae mediated by deletion of the histone chaperone ASF1/CIA1. Genes Cells 6, 1043-1054.
18. Sekiguchi, T., Nakashima, T., Hayashida, T., Kuraoka, A., Hashimoto, S., Tsuchida, N., Shibata, Y., Hunter, T., and Nishimoto, T. (1995) Apoptosis is induced in BHK cells by the tsBN462/13 mutation in the CCG1/TAFII250 subunit of the TFIID basal transcription factor. Exp. Cell Res. 218, 490-498.
19. Del Carratore, R., Della Croce, C., Simili, M., Taccini, E., Scavuzzo, M., and Sbrana, S. (2002) Cell cycle and morphological alterations as indicative of apoptosis promoted by UV irradiation in S. cerevisiae. Mutat. Res. 513, 183-191.
20. Blanchard, F., Rusiniak, M. E., Sharma, K., Sun, X., Todorov, I., Castellano, M. M., Gutierrez, C., Baumann, H., and Burhans, W. C. (2002) Targeted destruction of DNA replication protein cdc6 by cell death pathways in mammals and yeast. Mol. Biol. Cell 13, 1536-1549.
21. Jesenberger, V., and Jentsch, S. (2002) Deadly encounter: ubiquitin meets apoptosis. Nat. Rev. Mol. Cell Biol. 3, 112-121.
22. Qi, H., Li, T. K., Kuo, D., Nur, E. K. A., and Liu, L. F. (2003) Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast. J. Biol. Chem. 278, 15136-15141.
23. Madeo, F., Engelhardt, S., Herker, E., Lehmann, N., Maldener, C., Proksch, A., Wissing, S., and Frohlich, K. U. (2002) Apoptosis in yeast: a new model system with applications in cell biology and medicine. Curr. Genet. 41, 208-216.
24. Hirao, A., Cheung, A., Duncan, G., Girard, P. M., Ella, A. J., Wakeham, A., Okada, H., Sarkissian, T., Wong, J. A., Sakai, T., et al. (2002) Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Mol. Cell Biol. 22, 6521-6532.
25. Raj, K., Ogston, P., and Beard, P. (2001) Virus-mediated killing of cells that lack p53 activity. Nature 412, 914-917.
26. Nur, E. K. A., Li, T. K., Zhang, A., Qi, H., Hars, E. S., and Liu, L. F. (2003) Single-stranded DNA induces Ataxia Telangiectasia Mutant (ATM)/p53-dependent DNA damage and apoptotic signals. J. Biol. Chem. 278, 12475-12481.
27. Ha, L., Ceryak, S., and Patierno, S. R. (2003) Chromium (VI) activates Ataxia Telangiectasia Mutated (ATM) protein. Requirement of ATM for both apoptosis and recovery from terminal growth arrest. J. Biol. Chem. 278, 17885-17894.
28. Lin, W. C., Lin, F. T., and Nevins, J. R. (2001) Selective induction of E2FI in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev. 15, 1833-1844.
29. Takai, H., Naka, K., Okada, Y., Watanabe, M., Harada, N., Saito, S., Anderson, C. W., Appella, E., Nakanishi, M., Suzuki, H., et al. (2002) Chk2-deficient mice exhibit radioresistance and defective p53-mediated ranscription. EMBO J. 21, 5195-5205.
30. Xu, J., Xin, S., and Du, W. (2001) Drosophila Chk2 is required for DNA damage-mediated cell cycle arrest and apoptosis. FEBS Lett. 508, 394-398.
31. Yang, S., Kuo, C., Bisi, J. E., and Kim, M. K. (2002) PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2. Nat. Cell Biol. 4, 865-870.
32. Stevens, C., Smith, L., and La Thangue, N. B. (2003) Chk2 activates E2F-1 in response to DNA damage. Nat. Cell Biol. 5, 401-409.
33. Yoshida, K., Wang, H. G., Miki, Y., and Kufe, D. (2003) Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9. EMBO J. 22, 1431-1441.
34. Komatsu, K., Hopkins, K. M., Lieberman, H. B., and Wang, H. (2000) Schizosaccharomyces pombe Rad9 contains a BH3-like region and interacts with the anti-apoptotic protein Bcl-2. FEBS Lett. 481, 122-126.
35. Chen, M. J., Lin, Y. T., Lieberman, H. B., Chen, G., and Lee, E. Y. (2001) ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation. J. Biol. Chem. 276, 16580-16586.
36. Baskaran, R., Wood, L. D., Whitaker, L. L., Canman, C. E., Morgan, S. E., Xu, Y., Barlow, C., Baltimore, D., Wynshaw-Boris, A., Kastan, M. B., et al. (1997) Ataxia telangiectasia mutant protein activates c-Ab1 tyrosine kinase in response to ionizing radiation [see comments]. Nature 387, 516-519.
37. Shafman, T., Khanna, K. K., Kedar, P., Spring, K., Kozlov, S., Yen, T., Hobson, K., Gatei, M., Zhang, N., Watters, D., et al. (1997) Interaction between ATM protein and c-Abl in response to DNA damage [see comments]. Nature 387, 520-523.
38. Komatsu, K., Miyashita, T., Hang, H., Hopkins, K. M., Zheng, W., Cuddeback, S., Yamada, M., Lieberman, H. B., and Wang, H. G. (2000) Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosis. Nat. Cell Biol. 2, 1-6.
39. Watanabe, K., Morishita, J., Umezu, K., Shirahige, K., and Maki, H. (2002) Involvement of RAD9-dependent damage checkpoint control in arrest of cell cycle, induction of cell death, and chromosome instability caused by defects in origin recognition complex in Saccharomyces cerevisiae. Eukaryot. Cell 1, 200-212.
40. Sears, R. C., and Nevins, J. R. (2002) Signaling networks that link cell proliferation and cell fate. J. Biol. Chem. 277, 11617-11620.
41. Seoane, J., Le, H. V., and Massague, J. (2002) Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature 419, 729-734.
42. Gartel, A. L., and Tyner, A. L. (2002) The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol. Cancer Ther. 1, 639-649.
43. Jin, Y. H., Yoo, K. J., Lee, Y. H., and Lee, S. K. (2000) Caspase 3-mediated cleavage of p21WAF1/CIP1 associated with the cyclin A-cyclin-dependent kinase 2 complex is a prerequisite for apoptosis in SK-HEP-1 cells. J. Biol. Chem. 275, 30256-30263.
44. King, K. L., and Cidlowski, J. A. (1995) Cell cycle and apoptosis: common pathways to life and death. J. Cell Biochem. 58, 175-180.
45. Marchetti, P., Hirsch, T., Zamzami, N., Castedo, M., Decaudin, D., Susin, S. A., Masse, B., and Kroemer, G. (1996) Mitochondrial permeability transition triggers lymphocyte apoptosis. J. Immunol. 157, 4830-4836.
46. Pelizon, C., d'Adda di Fagagna, F., Farrace, L., and Laskey, R. A. (2002) Human replication protein Cdc6 is selectively cleaved by caspase 3 during apoptosis. EMBO Rep. 3, 780-784.
47. Hekmat-Nejad, M., You, Z., Yee, M. C., Newport, J. W., and Cimprich, K. A. (2000) Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint. Curr. Biol. 10, 1565-1573.
48. Weinreich, M., Liang, C., Chen, H. H., and Stillman, B. (2001) Inaugural Article: Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle. Proc. Natl. Acad. Sci. USA 98, 11211-11217.
49. Clay-Farrace, L., Pelizon, C., Santamaria, D., Pines, J., and Laskey, R. A. (2003) Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1. EMBO J. 22, 704-712.
50. Xu, Q., and Reed, J. C. (1998) Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast. Mol. Cell 1, 337-346.
51. Zhang, H., Xu, Q., Krajewski, S., Krajewska, M., Xie, Z., Fuess, S., Kitada, S., Pawlowski, K., Godzik, A., and Reed, J. C. (2000) BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins. Proc. Natl. Acad. Sci. USA 97, 2597-2602.
52. Sawada, M., Sun, W., Hayes, P., Leskov, K., Boothman, D. A., and Matsuyama, S. (2003) Ku70 suppresses the apoptotic translocation of Bax to mitochondria. Nat. Cell Biol. 5, 320-329.
53. Brezniceanu, M. L., Volp, K., Bosser, S., Solbach, C., Lichter, P., Joos, S., and Zornig, M. (2003) HMGB1 inhibits cell death in yeast and mammalian cells and is abundantly expressed in human breast carcinoma. Faseb J. 17, 1295-1297.