Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1

EMBO Journal

Volumn 22, Issue 3, 2003, Pages 704-712

  Clay Farrace, Lorena ^a,b,c   Pelizon, Cristina ^a,b,c   Santamaria, David ^a,c   Pines, Jonathon ^b,c   Laskey, Ronald A ^a,b,c  

^a HUTCHISON MRC RESEARCH CENTRE   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Cdc6; Cell cycle; Checkpoint pathway; G2 phase; HuCdc6

Indexed keywords

7 HYDROXYSTAUROSPORINE; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 6; CHECKPOINT KINASE 1; PHOSPHOTRANSFERASE; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G2 PHASE; DNA REPLICATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; HUMAN; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN FUNCTION;

ALKALOIDS; CELL CYCLE PROTEINS; DNA DAMAGE; DNA REPLICATION; ENZYME INHIBITORS; HELA CELLS; HUMANS; MICROINJECTIONS; MITOSIS; MUTATION; NUCLEAR PROTEINS; PROTEIN KINASES; RECOMBINANT FUSION PROTEINS; STAUROSPORINE;

METAZOA;

EID: 0037415724     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg046     Document Type: Article

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