Hypoxia enhances β-amyloid-induced apoptosis in rat cultured hippocampal neurons

Japanese Journal of Pharmacology

Volumn 90, Issue 4, 2002, Pages 321-327

  Egashira, Nobuaki ^a   Iwasaki, Katsunori ^a   Ishibashi, Motoki ^a   Hatip Al Khatib, Izzetin ^a   Wolozin, Benjamin ^a,b   Mishima, Kenichi ^a   Irie, Keiichi ^a   Fujiwara, Michihiro ^a  

^a FUKUOKA UNIVERSITY   (Japan)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Apoptosis; CNQX; Hypoxia; MK 801; amyloid

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR ANTAGONIST; AMYLOID BETA PROTEIN; CARBOBENZOXY ASPARTYL [(2,6 DICHLOROBENZOYL)OXY]METHANE; DIZOCILPINE; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CELL COUNT; CELL HYPOXIA; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; DRUG EFFECT; EMBRYO; ENZYME INHIBITION; HIPPOCAMPUS; NERVE CELL CULTURE; NICK END LABELING; NONHUMAN; RAT; RAT STRAIN; SYMPTOM;

EID: 0036956436     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.90.321     Document Type: Article

References (42)

1. Kokmen E, Whisnant JP, O'Fallon WM, Chu CP and Beard CM: Dementia after ischemic stroke: A population-based study in Rochester, Minnesota (1960-1984). Neurology 46, 154-159 (1996)
2. Skoog I, Lernfelt B, Landahl S, Palmertz B, Andreasson L-A, Nilsson L, Persson G, Oden A and Svanborg A: 15-Year longitudinal study of blood pressure and dementia. Lancet 347, 1141 - 1145 (1996)
3. Snowdon DA, Greiner LH, Mortimer JA, Riley KP, Greiner PA and Markesbery WR: Brain infarction and the clinical expression fo Alzheimer disease. The Nun Study. JAMA 277, 813-817 (1997)
4. Kalariai RN and Harik SI: Reduced glucose transporter at the blood-brain barrier and in cerebral cortex in Alzheimer disease. J Neurochem 53, 1083 - 1088 (1989)
5. Simpson IA, Chundu KR, Davies-Hill T, Honer WG and Davies P: Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease. Ann Neurol 35, 546-551 (1994)
6. Swerdlow R, Marcus DL, Landman J, Kooby D, Frey W and Freedman ML: Brain glucose metabolism in Alzheimer's disease. Am J Med Sci 308, 141-144 (1993)
7. de la Torre JC and Mussivand T: Can disturbed brain microcirculation cause Alzheimer's disease? Neurol Res 15, 146-153 (1993)
8. de la Torre JC: Impaired cerebromicrovascular perfusion. Summary of evidence in support of its causality in Alzheimer's disease. Ann NY Acad Sci 924, 136 - 152 (2000)
9. de la Torre JC Stefano GB: Evidence that Alzheimer's disease is a microvascular disorder: The role of constitutive nitric oxide. Brain Res Rev 34, 119 - 136 (2000)
10. Selkoe DJ: Biochemistry of altered brain proteins in Alzheimer's disease. Annu Rev Neurosci 12, 463 - 490 (1989)
11. Selkoe DJ: Deciphering Alzheimer's disease: The amyloid precursor protein yields new clues. Science 248, 1058-1060 (1990)
12. Honig LS and Rosenberg RN: Apoptosis and neurologic disease. Am J Med 108, 317 - 330 (2000)
13. Offen D, Elkon H and Melamed E: Apoptosis as a general cell death pathway in neurodegenerative disease. J Neural Trans Suppl 58, 153 - 166 (2000)
14. Shimohama S: Apoptosi in Alzheimer's disease - An update. Apoptosis 5, 9 - 16 (2000)
15. Pike CJ, Walencewicz AJ, Glabe CG and Cotman CW: In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res 563, 311 - 314 (1991)
16. Behl C, Davis J, Cole GM and Schubert D: Vitamin E protects nerve cells from amyloid beta protein toxicity. Biochem Biophys Res Commun 186, 944 - 950 (1992)
17. Mattson MP: Cellular actions of β-amyloid precursor protein and its soluble and fibrillogenic derivatives. Physiol Rev 77, 1081 - 1132 (1997)
18. Loo DT, Copani A, Pike CJ, Whittemore ER, Walencewicz AJ and Cotman CW: Apoptosis is induced by β-amyloid in cultured centra nervous system neurons. Proc Natl. Acad Sci USA 90, 7951 - 7955 (1993)
19. Cotman CW, Whittemore ER, Watt JA, Anderson AJ and Loo DT: Possible role of apoptosis in Alzheimer's diesease. Ann NY Acad Sci 747, 36 - 49 (1994)
20. Iwasaki K, Sunderland T, Kusiak JW and Wolozin B: Changes in gene transcription during aβ-mediated cell death. Mol Psychiatry 1, 65 - 71 (1996)
21. Estus S, Tucker HM, Van Rooyen C, Wright S, Brigham EF, Wogulis M and Rydel RE: Aggregated amyloid-β protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction. J Neurosci 17, 7736 - 7745 (1997)
22. Jordan J, Galino MF and Miller RJ: Role of calpain- and interleukin-1 beta converting enzyme-like proteases in the beta-amyloid-induced death of rat hippocampal neurons in culture. J Neurochem 68, 1612 - 1621 (1997)
23. Mattson MP, Partin J and Begley JG: Amyloid β-peptide induces apoptosis-related events in synapses and dendrities. Brain Res 807, 167 - 176 (1998)
24. Chan SL, Griffin WST and Mattson MP: Evidence for caspase-mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease. J Neurosci Res 57, 315 - 323 (1999)
25. Harada J and Sugimoto M: Activation of caspase-3 in β-amyloid-induced apoptosis of cultured rat cortical neurons. Brain Res 842, 311 - 323 (1999)
26. Koh JY, Yang LL and Cotman CW: Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res 533, 315 - 320 (1990)
27. Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I, and Rydel RE: β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 12, 376 - 389 (1992)
28. Yokota M, Saido TC, Tani E, Yamaura I and Minami N: Cytotoxic fragment of amyloid precursor protein accumulates in hippocampus after global forebrain ischemia. J Cereb Blood Flow Metab 16, 1219 - 1223 (1996)
29. Jendroska K, Hoffmann OM and Patt S: Amyloid β peptide and precursor protein (APP) in mild and severe brain ischemia. Ann NY Acad Sci 826, 401 - 405 (1997)
30. Lin B, Schmidt-Kastner R, Busto R and Ginsberg MD: Progressive parenchymal deposition of β-amyloid precursor protein in rat brain following global cerebral ischemia. Acta Neuropathol 97, 359 - 368 (1999)
31. Banasiak KJ, Xia Y and Haddad GG: Mechanisms underlying hypoxia-induced neuronal apoptosis. Prog Neurobiol 62, 215 - 249 (2000)
32. 2+ concentration changes in cultured postnatal rat hippocampal neurons. Neuroscience 93, 1003 - 1016 (1999)
33. Iwasaki K, Isaacs KR and Jacobowitz DM: Brain-derived neurotrophic factor stimulates neurite outgrowth in a calretinin-enriched neuronal culture system. Int J Dev Neurosci 16, 135 - 145 (1998)
34. Kirino T: Delayed neuronal death. Neuropathology Suppl 20, S95 - S97 (2000)
35. Rogers DC and Hunter AJ: Dissociation of effects of glutamate receptor antagonists on excitotoxic and hypoxic neuronal cell death in a novel rat cortical culture system. Brain Res Bull 44, 131 - 139 (1997)
36. 2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS. Neuron 15, 193 - 204 (1995)
37. 2+-permeable AMPA receptors in neurological disorders. Trends Neurosci 20, 464 - 470 (1997)
38. Sheardown MJ, Suzdak PD and Nordholm L: AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h. Eur J Pharmacol 236, 347 - 353 (1993)
39. 2+ ionophore-induced apoptosis on cultured embryonic rat cortical neurons. Brain Res 652, 65 - 70 (1994)
40. Oguro K, Oguro N, Kojima T, Grooms SY, Calderone A, Zheng X, Bennett MVL and Zukin RS: Knockdown of AMPA receptor GluR2 expression causes delayed neurodegeneration and increases damage by sublethal ischemia in hippocampal CA1 and CA3 neurons. J Neurosci 19, 9218 - 9227 (1999)
41. Busciglio J, Yeh J and Yankner BA: Beta;-Amyloid neurotoxicity in human cortical culture is not mediated by excitotoxins. J Neurochem 61, 1565 - 1568 (1993)
42. Bossenmeyer-Pourie C, Koziel V and Daval JL: Involvement of caspase-1 proteases in hypoxic brain injury. Effects of their inhibitors in developing neurons. Neuroscience 95, 1157 - 1165 (2000)