A phosphatidylinositol 3-kinase inhibitor wortmannin induces radioresistant DNA synthesis and sensitizes cells to bleomycin and ionizing radiation

International Journal of Cancer

Volumn 78, Issue 5, 1998, Pages 642-647

  Hosoi, Yoshio ^a   Miyachi, Hideo ^a   Matsumoto, Yoshihisa ^b   Ikehata, Hironobu ^a   Komura, Jun Ichiro ^a   Ishii, Keiichiro ^a   Zhao, Heng Jiang ^a   Yoshida, Masayuki ^a   Takai, Yoshihiro ^a   Yamada, Shougo ^a   Suzuki, Norio ^b   Ono, Tetsuya ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN;

ARTICLE; ATAXIA TELANGIECTASIA; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RISK; DNA SYNTHESIS; DRUG USE; GLIOBLASTOMA; HUMAN; HUMAN CELL; IONIZING RADIATION; PRIORITY JOURNAL; RADIOSENSITIVITY; SEQUENCE HOMOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; CELL CYCLE PROTEINS; DNA; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; ENZYME INHIBITORS; HUMANS; MICE; MICE, SCID; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RADIATION-SENSITIZING AGENTS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0031765340     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19981123)78:5<642::AID-IJC19>3.0.CO;2-3     Document Type: Article

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