Role of the actin bundling protein fascin in growth cone morphogenesis: Localization in filopodia and lamellipodia

Cell Motility and the Cytoskeleton

Volumn 48, Issue 2, 2001, Pages 109-120

  Cohan, Christopher S ^a   Welnhofer, Elizabeth A ^a,b   Zhao, Lin ^a,b   Matsumura, Fumio ^a,b   Yamashiro, Shigeko ^a,b  

^a UNIVERSITY AT BUFFALO   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Actin bundles; Actin cytoskeleton; Growth cone formation; Neurons

Indexed keywords

ACTIN BINDING PROTEIN; FASCIN; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR PROMOTER; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; BINDING AFFINITY; CELL MATURATION; CELL MOTILITY; CONTROLLED STUDY; CYTOSKELETON; GROWTH CONE; MORPHOGENESIS; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SNAIL;

ACTINS; ANIMALS; CARCINOGENS; CARRIER PROTEINS; GREEN FLUORESCENT PROTEINS; GROWTH CONES; HELIX (SNAILS); IMAGE PROCESSING, COMPUTER-ASSISTED; INDICATORS AND REAGENTS; LUMINESCENT PROTEINS; MICROFILAMENT PROTEINS; MICROSCOPY, VIDEO; PSEUDOPODIA; STAINING AND LABELING; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS;

GASTROPODA; HELISOMA;

EID: 0035140487     PISSN: 08861544     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0169(200102)48:2<109::AID-CM1002>3.0.CO;2-G     Document Type: Article

References (26)

1. Parallel actin bundles and their multiple actin-bundling proteins
2. Drosophila singed, a fascin homolog, is required for actin bundle formation during oogenesis and bristle extension
3. Structure of F-actin needles from extracts of sea urchin oocytes
4. cDNA cloning and expression of the human homology of the sea urchin fascin and Drosophila singed genes which encodes an actin-binding protein
5. Fascins, a family of actin bundling proteins
6. Cloning and expression of a murine fascin homolog from mouse brain
7. Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone
8. A vertebrate homolog of the actin bundling protein fascin
9. Drebrin, a development-associated brain protein from rat embryo, causes the dissociation of tropomyosin from actin filaments
10. Preparation and purification of polymerized actin from sea urchin egg extracts
11. Regulated actin cytoskeleton assembly at filopodium tips controls their extension and retraction
12. Epstein-Barr virus induces expression in B lymphocytes of a novel gene encoding an evolutionarily conserved 55-kilodalton actin-bundling protein
13. Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin
14. The incorporation of actin and fascin into the cytoskeleton of filopodial sea urchin coelomocytes
15. Inhibition by drebrin of the actin-bundling activity of brain fascin, a protein localized in filopodia of growth cones
16. a-actinins, calspectin (brain spectrin or fodrin), and actin participate in adhesion and movement of growth cones
17. F actin bundles in Drosophila bristles. I. Two filament cross-links are involved in bundling
18. Why are two different cross-linkers necessary for actin bundle formation in vivo and what does each cross-link contribute?
19. Actin dynamics and organization during growth cone morphogenesis in Helisoma neurons
20. Calcium influx alters actin bundle dynamics and retrograde flow in Helisoma growth cones
21. The role of conditioning factors in the formation of growth cones and neurites from the axon stump after axotomy
22. Changes in the F-actin cytoskeleton during neurosensory bristle development in Drosophila: The role of singed and forked proteins
23. Phosphorylation of human fascin inhibits its actin binding and bundling activities
24. Fascin, a actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells
25. Purification and characterization of an f-actin-bundling 55-kilodalton protein from HeLa cells
26. Intracellular localization of the 55-kD actin-bundling protein in cultured cells: Spatial relationships with actin, alpha-actin, tropomyosin, and fimbrin