Dynamic microtubule ends are required for growth cone turning to avoid an inhibitory guidance cue

Journal of Neuroscience

Volumn 17, Issue 9, 1997, Pages 3085-3095

  Challacombe, Jean F ^a   Snow, Diane M ^a,b   Letourneau, Paul C ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

actin filament; chondroitin sulfate proteoglycan; dynamic instability; growth cone; microtubule; turning

Indexed keywords

ACTIN; ALPHA TUBULIN; FIBRONECTIN; PACLITAXEL; PROTEOCHONDROITIN SULFATE; TYROSINE; VINBLASTINE;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CHICK EMBRYO; CONTROLLED STUDY; CYTOSKELETON; GROWTH CONE; MICROTUBULE ASSEMBLY; NERVE FIBER GROWTH; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; SPINAL GANGLION;

EID: 0030898065     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-09-03085.1997     Document Type: Article

References (18)

1. Arregui C, Busciglio A, Caceres A, Barra HS (1991) Tyrosinated and detyrosinated microtubules in axonal processes of cerebellar macroneurons grown in culture. J Neurosci Res 28:171-181.
2. Avila J, Dominguez J, Diaz-Nido J (1994) Regulation of microtubule dynamics by microtubule-associated protein expression and phosphorylation during neuronal development. Int J Dev Biol 38:13-25.
3. Baas PW, Black MM (1990) Individual microtubules in the axon consist of domains that differ in both composition and stability. J Cell Biol 111:495-509.
4. Baas PW, Ahmad FJ, Pienkowski TP, Brown A, Black MM (1993) Sites of microtubule stabilization for the axon. J Neurosci 13:2177-2185.
5. Bentley D, O'Connor TP (1994) Cytoskeletal events in growth cone steering. Curr Opin Neurobiol 4:43-48.
6. Bershadsky AD, Vaisberg EA, Vasiliev JM (1991) Pseudopodial activity at the active edge of migrating fibroblasts is decreased after drug-induced microtubule depolymerization. Cell Motil Cytoskeleton 19:152-158.
7. Black MM (1987) Taxol interferes with the interaction of microtubule-associated proteins with microtubules in cultured neurons. J Neurosci 7:3695-3702.
8. Brelje TC, Wessendorf MW, Sorenson RL (1993) Multicolor laser scanning confocal immunofluorescence microscopy: practical applications and limitations. Methods Cell Biol 38:97-181.
9. Brown A, Li Y, Slaughter T, Black MM (1993) Composite microtubules of the axon: quantitative analysis of tyrosinated and acetylated tubulin along individual axons. J Cell Sci 104:339-352.
10. Bulinski JC, Gundersen GG (1991) Stabilization and post-translational modification of microtubules during cellular morphogenesis. BioEssays 13:285-292.
11. Carrino DA, Kaplan AI (1985) Isolation and characterization of proteoglycans synthesized in ovo by embryonic chick cartilage and new bone. J Biol Chem 260:122-127.
12. Challacombe JF, Snow DM, Letourneau PC (1996) Actin filament bundles are required for microtubule reorientation during growth cone turning to avoid an inhibitory guidance cue. J Cell Sci 109:2031-2040.
13. Chapin SJ, Bulinski JC (1992) Microtubule stabilization by assembly-promoting microtubule-associated proteins: a repeat performance. Cell Motil Cytoskeleton 23:236-243.
14. Chapin SJ, Bulinski JC, Gundersen GG (1991) Microtubule bundling in cells. Nature 349:24.
15. Conover WJ (1980) Practical nonparametric statistics, 2nd Ed. New York: Wiley.
16. Davis A, Sage CR, Dougherty CA, Farrell KW (1994) Microtubule dynamics modulated by guanosine triphosphate hydrolysis activity of β-tubulin. Science 264:839-841.
17. Yu W, Baas PW (1995) The growth of the axon is not dependent upon net microtubule assembly at its distal tip. J Neurosci 15:6827-6833.
18. Zheng J, Buxbaum RE, Heidemann SR (1993) Investigation of microtubule assembly and organization accompanying tension-induced neurite initiation. J Cell Sci 104:1239-1250.