Phosphorylation-dependent localization of microtubule-associated protein MAP2c to the actin cytoskeleton

Molecular Biology of the Cell

Volumn 11, Issue 10, 2000, Pages 3573-3587

  Ozer, R S ^a   Halpain, S ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; FORSKOLIN; MICROTUBULE ASSOCIATED PROTEIN 2; RECOMBINANT PROTEIN;

ARTICLE; CYTOSKELETON; ENZYME ACTIVITY; HELA CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MASS SPECTROMETRY; MICROTUBULE; PLASMID; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS;

EID: 0033786279     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.11.10.3573     Document Type: Article

References (50)

1. Positive and negative regulatory mechanisms that mediate long-term memory storage
2. Stimulation of tubulin polymerization by MAP-2
3. Ontogenetic changes in the cyclic adenosine 3',5'-monophosphate-stimulatable phosphorylation of cat visual cortex proteins, particularly of microtubule-associated protein 2 (MAP2): Effects of normal and dark rearing and of the exposure to light
4. Identification of posttranslational modification sites by site-directed mutagenesis
5. Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding
6. The development of cell processes induced by tau protein requires phosphorylation of serine 262 and 356 in the repeat domain and is inhibited by phosphorylation in the proline-rich domains
7. Tau-mediated process outgrowth is differentially altered by the expression of MAP2b and MAP2c in Sf9 cells
8. Bundling of microtubules in transfected cells does not involve an autonomous dimerization site on the MAP2 molecule
9. The multiple phosphorylation of the microtubule-associated protein MAP2 controls the MAP2:tubulin interaction
10. Suppression of MAP2 in cultured cerebellar macroneurons inhibits minor neurite formation
11. Expression of various microtubule-associated protein 2 forms in the developing mouse brain and in cultured neurons and astrocytes
12. The tubulin-binding sequence of brain microtubule-associated proteins, tau and MAP-2, is also involved in actin binding
13. Microtubule-associated protein 2c reorganizes both microtubules and microfilaments into distinct cytological structures in an actin-binding protein-280-deficient melanoma cell line
14. Dissection of memory formation: From behavioral pharmacology to molecular genetics
15. An isoform of microtubule-associated protein 2 (MAP2) containing four repeats of tubulin-binding motif
16. Actin depolymerization induces process formation on MAP2-transfected non-neuronal cells
17. Complete sequence of rat MAP2d, a novel MAP2 isoform
18. Recombinant microtubule-associated protein 2c reduces the dynamic instability of individual microtubules
19. Activation of NMDA receptors induces rapid dephosphorylation of the cytoskeletal protein MAP2
20. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1
21. Protein-kinase-C-catalyzed phosphorylation of the microtubule-binding domain of microtubule-associated protein 2 inhibits its ability to induce tubulin polymerization
22. Mitogen-activated-protein-kinase-catalyzed phosphorylation of microtubule-associated proteins, microtubule-associated protein 2 and microtubule-associated protein 4, induces an alteration in their function
23. Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110(mark)
24. Cytoskeletal plasticity in cells expressing neuronal microtubule-associated proteins
25. Genomic structure of human microtubule-associated protein 2 (MAP-2) and characterization of additional MAP-2 isoforms
26. Juvenile and mature MAP2 isoforms induce distinct patterns of process outgrowth
27. Microtubule-associated protein MAP2 shares a microtubule binding motif with tau protein
28. Regulated association of microtubule-associated protein MAP2 with Src and Grb2: Evidence for MAP2 as a scaffolding protein
29. Intracellular messengers in the generation and degeneration of hippocampal neuroarchitecture
30. Resistance to antimitotic drugs in Chinese hamster ovary cells correlates with changes in the levels of polymerized tubulin
31. N-Methyl-D-aspartate stimulates the dephosphorylation of the microtubule-associated protein 2 and potentiates excitatory synaptic pathways in the rat hippocampus
32. Distribution of MAP2 in dendritic spines and its colocalization with actin
33. Phosphorylation of microtubule-associated proteins (MAPs) and pH of the medium control interactions between MAPs and actin filaments
34. The RII subunit of cAMP-dependent protein kinase binds to a common amino-terminal domain in microtubule-associated proteins 2A, 2B and 2C
35. Experience-dependent modifications in MAP2 phosphorylation in rat olfactory bulb
36. Postsynaptic mechanisms for bidirectional control of MAP2 phosphorylation by glutamate receptors
37. Differential expression of distinct microtubule-associated proteins during brain development
38. Localization and characterization of the binding site for the regulatory subunit of type II cAMP-dependent protein kinase on MAP2
39. Interaction of microtubule-associated protein 2 with actin filaments
40. Phosphorylation of microtubule-associated proteins regulates their interaction with actin filaments
41. Cyclic nucleotide- and Ca2+-independent phosphorylation of tubulin and microtubule-associated protein-2 by glycogen synthase (casein) kinase-1
42. Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein
43. Extensive cAMP-dependent and cAMP-independent phosphorylation of microtubule-associated protein 2
44. Microtubule rearrangement and bending during assembly of large curved microtubule bundles in mouse cochlear epithelial cells
45. Structure and phosphorylation of microtubule-associated protein 2 (MAP2)
46. A protein kinase bound to the projection portion of MAP2 (microtubule-associated protein 2)
47. Reorganisation of the microtubular cytoskeleton by embryonic microtubule-associated protein 2 (MAP2c)
48. Disassembly of microtubules by the actions of calmodulin-dependent protein kinase (kinase II) which occurs only in the brain tissues
49. Regulation of the interaction of actin filaments with microtubule-associated protein 2 by calmodulin-dependent protein kinase II
50. Cyclic GMP/cyclic GMP-dependent protein kinase system prevents excitotoxicity in an immortalized oligodendroglial cell line