Focal loss of actin bundles causes microtubule redistribution and growth cone turning

Journal of Cell Biology

Volumn 157, Issue 5, 2002, Pages 839-849

  Zhou, Feng Quan ^a   Waterman Storer, Clare M ^b   Cohan, Christopher S ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Actin bundles; Axon guidance; Cytoskeleton; Microtubules; Pathfinding

Indexed keywords

ACTIN;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; GROWTH CONE; MICROTUBULE; MOLECULAR DYNAMICS; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION;

ANIMALS; CELLS, CULTURED; GROWTH CONES; MICROFILAMENTS; MICROSCOPY, VIDEO; MICROTUBULES; NEURONS; PSEUDOPODIA; SNAILS;

ANIMALIA;

EID: 0037182576     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200112014     Document Type: Article

References (55)

1. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
2. NI-35/250/nogo-a: A neurite growth inhibitor restricting structural plasticity and regeneration of nerve fibers in the adult vertebrate CNS
3. Cyroskeletal events in growth cone steering
4. Regulating axon branch stability: The role of p190 RhoGAP in repressing a retraction signaling pathway
5. The organization of myosin and actin in rapid frozen nerve growth cones
6. Myosin IIB is required for growth cone motility
7. Actin filament bundles are required for microtubule reorientation during growth cone turning to avoid an inhibitory guidance cue
8. Dynamic microtubule ends are required for growth cone turning to avoid an inhibitory guidance cue
9. Navigational errors made by growth cones without filopodia in the embryonic Xenopus brain
10. Electrically and chemically mediated increases in intracellular calcium in neuronal growth cones
11. Role of actin bundling protein fascin in growth cone morphogenesis: Localization in filapodia and lamellipodia
12. A sensory role for neuronal growth cone filopodia
13. The adenomatous polyposis coli protein: In the limelight out at the edge
14. Localized collapsing cues can steer growth cones without inducing their full collapse
15. The organization of F-actin and microtubules in growth cones exposed to a brain-derived collapsing factor
16. Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone
17. Bridging cytoskeletal intersections
18. Neurotrophins and the dynamic regulation of the neuronal cytoskeleton
19. Inhibition of formation of filopodia after axotomy by inhibitors of protein tyrosine kinases
20. The cytoskeletons of isolated, neuronal growth cones
21. Evidence for microtubule capture by filopodial actin filaments in growth cones
22. Modulation of actin filament behavior by GAP-43 (neuromodulin) is dependent on the phosphorylation status of serine 41, the protein kinase C site
23. Calcium signalling in the guidance of nerve growth by netrin-1
24. Filopodial adhesion does not predict growth cone steering events in vivo
25. Microtubule targeting of substrate contacts promotes their relaxation and dissociation
26. Functional implications of neurotransmitter expression during axonal regeneration: Serotonin, but not peptides, auto-regulate axon growth of an identified central neuron
27. Mena is required for neutulation and commissure formation
28. Differences in the organization of actin in the growth cones compared with the neurites of cultured neurons from chick embryos
29. Myosin drives retrograde F-actin flow in neuronal growth cones
30. Cytoskeletal remodeling during growth conetarget interactions
31. Dopamine and serotonin inhibition of neurite elongation of different identified neurons
32. cAMP-dependent growth cone guidance by netrin-1
33. Phosphorylation-dependent localizable of microtubule-associated protein MAP2c to the actin cytoskeleton
34. Newt lung epithelial cells: Cultivation, use, and advantages for biochemical research
35. Phosphorylation of microtubule-associated proteins regulates their interaction with actin filaments
36. Tara, a novel F-actin binding protein, associates with the Trio guanine nucleotide exchange factor and regulates actin cytoskeletal organization
37. Cytoskeleton crosstalk during cell motility
38. Signal transduction underlying growth cone guidance by diffusible factors
39. cAMP-induced switching in turning direction of nerve growth cones
40. Transmitter-receptor interactions between growth cones of identified lymnaea neurons determine target cell selection in vitro
41. An emerging link between cytoskeletal dynamics and cell adhesion molecules in growth cone guidance
42. Substrate-cytoskeletal coupling as a mechanism for the regulation of growth cone motility, and guidance
43. The Ig superfamily cell adhesion molecule, apCAM, mediates growth cone steering by substrate-cytoskeletal coupling
44. Making the connection: Cytoskeletal rearrangements during growth cone guidance
45. The molecular biology of axon guidance
46. Novel features of the light chain of microtubule-associated protein MAP1B: Microtubule stabilization, self interaction, actin filament binding, and regulation by the heavy chain
47. Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cells
48. Actomyosin-based retrograde flow of microtubules in the lamella of migrating epithelial cells influences microtubule dynamic instability and turnover and is associated with microtubule breakage and treadmilling
49. Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts
50. Actin dynamics and organization during growth cone morphogenesis in Helisoma neurons
51. Microtubule reorganization is obligatory for growth cone turning
52. The tyrosine kinase Ab1 and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidance
53. Phosphorylation of human fascin inhibits its actin binding and bundling activities
54. Turning of nerve growth cones induced by localized increases in intracellular calcium ions
55. Growth cone collapse through coincident loss of actin bundles and leading edge actin without actin depolymerization J