Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: Role of matrix metalloproteinase-9 in early blood-brain barrier disruption?

Journal of Neuroscience

Volumn 23, Issue 25, 2003, Pages 8733-8742

  Kim, Gyung W ^a,b   Gasche, Yvan ^a,c   Grzeschik, Susanna ^a   Copin, Jean Christophe ^a,c   Maier, Carolina M ^a   Chan, Pak H ^a,d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Yonsei University College of Medicine   (South Korea)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^d STANFORD UNIVERSITY   (United States)

Author keywords

3 nitropropionic acid; Blood brain barrier; Evans blue extravasation; Matrix metalloproteinase; Oxidative stress; Striatum

Indexed keywords

3 NITROPROPIONIC ACID; COPPER ZINC SUPEROXIDE DISMUTASE; FREE RADICAL; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE; PROTEINASE; REACTIVE OXYGEN METABOLITE;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN INJURY; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVATION; ENZYME INHIBITION; GENE OVEREXPRESSION; IMMUNOREACTIVITY; MALE; MOUSE; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; ZYMOGRAPHY;

EID: 0141869839     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-25-08733.2003     Document Type: Article

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